DK0550737T3 - - Google Patents

Info

Publication number
DK0550737T3
DK0550737T3 DK92916803.7T DK92916803T DK0550737T3 DK 0550737 T3 DK0550737 T3 DK 0550737T3 DK 92916803 T DK92916803 T DK 92916803T DK 0550737 T3 DK0550737 T3 DK 0550737T3
Authority
DK
Denmark
Prior art keywords
tablets
excipient
mixture
disclosed
controlled release
Prior art date
Application number
DK92916803.7T
Other languages
Danish (da)
English (en)
Inventor
Anand R Baichwal
John N Staniforth
Original Assignee
Mendell Co Inc Edward
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mendell Co Inc Edward filed Critical Mendell Co Inc Edward
Application granted granted Critical
Publication of DK0550737T3 publication Critical patent/DK0550737T3/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/275—Nitriles; Isonitriles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2077—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cardiology (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Biophysics (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Cephalosporin Compounds (AREA)
  • Measuring Pulse, Heart Rate, Blood Pressure Or Blood Flow (AREA)
  • Separation By Low-Temperature Treatments (AREA)
  • External Artificial Organs (AREA)
DK92916803.7T 1991-07-25 1992-07-02 DK0550737T3 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/736,031 US5169639A (en) 1988-09-19 1991-07-25 Controlled release verapamil tablets

Publications (1)

Publication Number Publication Date
DK0550737T3 true DK0550737T3 (fr) 1997-02-17

Family

ID=24958214

Family Applications (1)

Application Number Title Priority Date Filing Date
DK92916803.7T DK0550737T3 (fr) 1991-07-25 1992-07-02

Country Status (17)

Country Link
US (1) US5169639A (fr)
EP (1) EP0550737B1 (fr)
JP (1) JPH0733339B2 (fr)
KR (1) KR0184308B1 (fr)
AT (1) ATE147974T1 (fr)
AU (1) AU649163B2 (fr)
CA (1) CA2092287C (fr)
DE (1) DE69217031T2 (fr)
DK (1) DK0550737T3 (fr)
ES (1) ES2099273T3 (fr)
FI (1) FI107231B (fr)
GR (1) GR3023086T3 (fr)
HU (1) HU218658B (fr)
IE (1) IE922411A1 (fr)
IL (1) IL102614A (fr)
MX (1) MX9204352A (fr)
WO (1) WO1993001803A1 (fr)

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US6726930B1 (en) * 1993-09-09 2004-04-27 Penwest Pharmaceuticals Co. Sustained release heterodisperse hydrogel systems for insoluble drugs
US5773025A (en) 1993-09-09 1998-06-30 Edward Mendell Co., Inc. Sustained release heterodisperse hydrogel systems--amorphous drugs
US6129930A (en) 1993-09-20 2000-10-10 Bova; David J. Methods and sustained release nicotinic acid compositions for treating hyperlipidemia at night
US6818229B1 (en) 1993-09-20 2004-11-16 Kos Pharmaceuticals, Inc. Intermediate release nicotinic acid compositions for treating hyperlipidemia
US6746691B2 (en) 1993-09-20 2004-06-08 Kos Pharmaceuticals, Inc. Intermediate release nicotinic acid compositions for treating hyperlipidemia having unique biopharmaceutical characteristics
US6080428A (en) 1993-09-20 2000-06-27 Bova; David J. Nicotinic acid compositions for treating hyperlipidemia and related methods therefor
US6676967B1 (en) 1993-09-20 2004-01-13 Kos Pharmaceuticals, Inc. Methods for reducing flushing in individuals being treated with nicotinic acid for hyperlipidemia
US5399358A (en) * 1993-11-12 1995-03-21 Edward Mendell Co., Inc. Sustained release formulations for 24 hour release of metroprolol
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US5399362A (en) * 1994-04-25 1995-03-21 Edward Mendell Co., Inc. Once-a-day metoprolol oral dosage form
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AU2068797A (en) * 1996-01-29 1997-08-20 Edward Mendell Co. Inc. Sustained release excipient
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MX9801835A (es) 1996-07-08 1998-08-30 Mendell Co Inc Edward Matriz de liberacion sostenida para medicamentos insolubles de dosis altas.
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US6056977A (en) 1997-10-15 2000-05-02 Edward Mendell Co., Inc. Once-a-day controlled release sulfonylurea formulation
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US6432448B1 (en) 1999-02-08 2002-08-13 Fmc Corporation Edible coating composition
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CN1228043C (zh) * 1999-09-30 2005-11-23 爱德华·孟岱尔股份有限公司 用于高溶解度药物的缓释基质
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JP2005515966A (ja) 2001-07-06 2005-06-02 エンドー ファーマシューティカルズ， インコーポレイティド 鎮痛薬としての使用のための６−ヒドロキシ−オキシモルホンの経口投与
EP1499295A4 (fr) * 2002-04-05 2006-04-05 Penwest Pharmaceuticals Co Formulations de metoprolol a liberation prolongee
US20040005359A1 (en) * 2002-06-27 2004-01-08 Cheng Xiu Xiu Controlled release oral dosage form
JP2005537298A (ja) * 2002-08-02 2005-12-08 ペンウェスト ファーマシューティカルズ カンパニー メトホルミンの徐放性製剤
US8389008B2 (en) 2003-09-19 2013-03-05 Penwest Pharmaceuticals Co. Delayed release dosage forms
CN101578096A (zh) * 2006-10-10 2009-11-11 潘威斯脱药物公司 稳健的缓释制剂
JP5463537B2 (ja) * 2008-02-22 2014-04-09 ＨＯＹＡ Ｔｅｃｈｎｏｓｕｒｇｉｃａｌ株式会社 分離方法
US20100159001A1 (en) * 2008-12-19 2010-06-24 Cardinal John R Extended-Release Pharmaceutical Formulations
US20100160363A1 (en) * 2008-12-19 2010-06-24 Aaipharma Services Corp. Extended-release pharmaceutical formulations

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Also Published As

Publication number Publication date
IE922411A1 (en) 1993-01-27
CA2092287A1 (fr) 1993-01-26
IL102614A (en) 1997-02-18
KR0184308B1 (ko) 1999-05-01
EP0550737B1 (fr) 1997-01-22
AU649163B2 (en) 1994-05-12
GR3023086T3 (en) 1997-07-30
DE69217031T2 (de) 1997-05-07
MX9204352A (es) 1993-04-01
HU218658B (hu) 2000-10-28
EP0550737A1 (fr) 1993-07-14
FI931342L (fi) 1993-03-25
ATE147974T1 (de) 1997-02-15
KR930701983A (ko) 1993-09-08
ES2099273T3 (es) 1997-05-16
DE69217031D1 (de) 1997-03-06
JPH06500576A (ja) 1994-01-20
FI931342A0 (fi) 1993-03-25
CA2092287C (fr) 1997-03-25
EP0550737A4 (en) 1993-12-15
FI107231B (fi) 2001-06-29
IL102614A0 (en) 1993-01-14
JPH0733339B2 (ja) 1995-04-12
US5169639A (en) 1992-12-08
HUT64221A (en) 1993-12-28
HU9300768D0 (en) 1993-06-28
WO1993001803A1 (fr) 1993-02-04
AU2403392A (en) 1993-02-23

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