DK0547059T3 - Pancreatic elastase-1-specific antibody, method for its extraction and test kits containing antibodies to form - Google Patents

Pancreatic elastase-1-specific antibody, method for its extraction and test kits containing antibodies to form

Info

Publication number
DK0547059T3
DK0547059T3 DK91912932.0T DK91912932T DK0547059T3 DK 0547059 T3 DK0547059 T3 DK 0547059T3 DK 91912932 T DK91912932 T DK 91912932T DK 0547059 T3 DK0547059 T3 DK 0547059T3
Authority
DK
Denmark
Prior art keywords
extraction
specific antibody
test kits
containing antibodies
kits containing
Prior art date
Application number
DK91912932.0T
Other languages
Danish (da)
Inventor
Ursula Scheefers-Borchel
Hans Scheefers
Andreas Sziegoleit
Original Assignee
Schebo Tech Medizinisch Biolog
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schebo Tech Medizinisch Biolog filed Critical Schebo Tech Medizinisch Biolog
Application granted granted Critical
Publication of DK0547059T3 publication Critical patent/DK0547059T3/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6424—Serine endopeptidases (3.4.21)
    • C12N9/6448—Elastases, e.g. pancreatic elastase (3.4.21.36); leukocyte elastase (3.4.31.37)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/40—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against enzymes

Abstract

The description relates to a process for obtaining a highly specific pancreas-elastasis-1-antibody which reacts with both bodily fluids and stools. Such an antibody is obtainable by immunisation with an antigen which has the amino acid sequence Thr-Met-Val-Ala-Gly-Asp-Ile-Arg or immunologically active partial peptides thereof. A test kit containing such antibodies is suitable for the diagnosis and monitoring of chronic and acute pancreatitis and mucoviscidosis in bodily fluids and/or stools.
DK91912932.0T 1990-07-28 1991-07-28 Pancreatic elastase-1-specific antibody, method for its extraction and test kits containing antibodies to form DK0547059T3 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE4023972 1990-07-28
DE4107765A DE4107765A1 (en) 1990-07-28 1991-03-11 PANCREAS ELASTASE-1 SPECIFIC ANTIBODY, A METHOD FOR ITS OBTAINMENT AND A TEST KIT CONTAINING SUCH ANTIBODIES

Publications (1)

Publication Number Publication Date
DK0547059T3 true DK0547059T3 (en) 1996-02-19

Family

ID=25895430

Family Applications (1)

Application Number Title Priority Date Filing Date
DK91912932.0T DK0547059T3 (en) 1990-07-28 1991-07-28 Pancreatic elastase-1-specific antibody, method for its extraction and test kits containing antibodies to form

Country Status (10)

Country Link
EP (1) EP0547059B1 (en)
JP (2) JPH05508770A (en)
AT (1) ATE128734T1 (en)
AU (1) AU646476B2 (en)
CA (1) CA2088354C (en)
DE (2) DE4107765A1 (en)
DK (1) DK0547059T3 (en)
ES (1) ES2080955T3 (en)
GR (1) GR3018483T3 (en)
WO (1) WO1992002630A1 (en)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE153695T1 (en) * 1990-11-26 1997-06-15 Akzo Nobel Nv METHOD FOR PRODUCING ANTIBODIES
EP0958833A1 (en) * 1998-05-20 1999-11-24 Erasmus Universiteit Rotterdam Methods and means for preventing or treating inflammation
DE19923892A1 (en) 1998-09-08 2000-03-09 Privates Inst Bioserv Gmbh Diagnostic procedure for the detection of pancreatic dysfunction
BR9913511A (en) * 1998-09-08 2001-06-05 Privates Inst Bioserv Gmbh Diagnostic process for the recognition of a disorder of pancreas function
GB9908458D0 (en) * 1999-04-13 1999-06-09 Queen Mary & Westfield College Enzyme
DE10157336B4 (en) * 2000-11-24 2007-07-19 Bioserv Analytik Und Medizinprodukte Gmbh Method for producing a test system and diagnostic method for detecting pancreatic function disorders
DE10101792B4 (en) * 2001-01-17 2004-03-18 Vivotec Biomedical Technologies Gmbh Procedure for the detection of pancreatic carcinoma or chronic pancreatitis and use of antibodies
JP2006226795A (en) * 2005-02-16 2006-08-31 Tokyo Univ Of Science Diagnostic marker of acute pancreatitis
CN111044723A (en) * 2018-10-12 2020-04-21 谢鲍生物科技股份公司 Novel test kit containing trypsin-1-specific antibodies and sample preparation device
WO2023100910A1 (en) * 2021-11-30 2023-06-08 株式会社Ｌｓｉメディエンス Method for measuring elastase 1 in feces

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5925183B2 (en) * 1978-07-05 1984-06-15 ダイナボット株式会社 Method for measuring elastase-1
JP2617299B2 (en) * 1986-09-17 1997-06-04 ダイナボット 株式会社 Immunoassay method for elastase 1

Also Published As

Publication number Publication date
EP0547059B1 (en) 1995-10-04
AU8100291A (en) 1992-03-02
ES2080955T3 (en) 1996-02-16
JPH1080272A (en) 1998-03-31
WO1992002630A1 (en) 1992-02-20
ATE128734T1 (en) 1995-10-15
DE4107765A1 (en) 1992-01-30
CA2088354A1 (en) 1992-01-29
CA2088354C (en) 1999-09-28
DE59106634D1 (en) 1995-11-09
AU646476B2 (en) 1994-02-24
EP0547059A1 (en) 1993-06-23
GR3018483T3 (en) 1996-03-31
JPH05508770A (en) 1993-12-09

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