AU8100291A - Pancreas-elastasis-1-specific antibody, a process for obtaining it and a test kit containing such antibodies - Google Patents

Pancreas-elastasis-1-specific antibody, a process for obtaining it and a test kit containing such antibodies

Info

Publication number
AU8100291A
AU8100291A AU81002/91A AU8100291A AU8100291A AU 8100291 A AU8100291 A AU 8100291A AU 81002/91 A AU81002/91 A AU 81002/91A AU 8100291 A AU8100291 A AU 8100291A AU 8100291 A AU8100291 A AU 8100291A
Authority
AU
Australia
Prior art keywords
elastasis
antibodies
obtaining
test kit
pancreas
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
AU81002/91A
Other versions
AU646476B2 (en
Inventor
Hans Scheefers
Ursula Scheefers-Borchel
Andreas Sziegoleit
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
ScheBo Tech Medizinisch-Biologische Forschungsgesellschaft mbH
Original Assignee
ScheBo Tech Medizinisch-Biologische Forschungsgesellschaft mbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ScheBo Tech Medizinisch-Biologische Forschungsgesellschaft mbH filed Critical ScheBo Tech Medizinisch-Biologische Forschungsgesellschaft mbH
Publication of AU8100291A publication Critical patent/AU8100291A/en
Application granted granted Critical
Publication of AU646476B2 publication Critical patent/AU646476B2/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6424—Serine endopeptidases (3.4.21)
    • C12N9/6448—Elastases, e.g. pancreatic elastase (3.4.21.36); leukocyte elastase (3.4.31.37)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/40—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against enzymes

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Wood Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Immunology (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • External Artificial Organs (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Abstract

The description relates to a process for obtaining a highly specific pancreas-elastasis-1-antibody which reacts with both bodily fluids and stools. Such an antibody is obtainable by immunisation with an antigen which has the amino acid sequence Thr-Met-Val-Ala-Gly-Asp-Ile-Arg or immunologically active partial peptides thereof. A test kit containing such antibodies is suitable for the diagnosis and monitoring of chronic and acute pancreatitis and mucoviscidosis in bodily fluids and/or stools.
AU81002/91A 1990-07-28 1991-07-28 Pancreas-elastasis-1-specific antibody, a process for obtaining it and a test kit containing such antibodies Ceased AU646476B2 (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
DE4023972 1990-07-28
DE4023972 1990-07-28
DE4107765 1991-03-11
DE4107765A DE4107765A1 (en) 1990-07-28 1991-03-11 PANCREAS ELASTASE-1 SPECIFIC ANTIBODY, A METHOD FOR ITS OBTAINMENT AND A TEST KIT CONTAINING SUCH ANTIBODIES

Publications (2)

Publication Number Publication Date
AU8100291A true AU8100291A (en) 1992-03-02
AU646476B2 AU646476B2 (en) 1994-02-24

Family

ID=25895430

Family Applications (1)

Application Number Title Priority Date Filing Date
AU81002/91A Ceased AU646476B2 (en) 1990-07-28 1991-07-28 Pancreas-elastasis-1-specific antibody, a process for obtaining it and a test kit containing such antibodies

Country Status (10)

Country Link
EP (1) EP0547059B1 (en)
JP (2) JPH05508770A (en)
AT (1) ATE128734T1 (en)
AU (1) AU646476B2 (en)
CA (1) CA2088354C (en)
DE (2) DE4107765A1 (en)
DK (1) DK0547059T3 (en)
ES (1) ES2080955T3 (en)
GR (1) GR3018483T3 (en)
WO (1) WO1992002630A1 (en)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA919299B (en) * 1990-11-26 1992-08-26 Akzo Nv Method for the production of antibodies
EP0958833A1 (en) * 1998-05-20 1999-11-24 Erasmus Universiteit Rotterdam Methods and means for preventing or treating inflammation
DE19923892A1 (en) 1998-09-08 2000-03-09 Privates Inst Bioserv Gmbh Diagnostic procedure for the detection of pancreatic dysfunction
ATE332504T1 (en) * 1998-09-08 2006-07-15 Bioserv Analytik Und Medizinpr DIAGNOSTIC METHOD FOR DETECTING A PANCREATIC FUNCTION DISORDER
GB9908458D0 (en) * 1999-04-13 1999-06-09 Queen Mary & Westfield College Enzyme
DE10157336B4 (en) * 2000-11-24 2007-07-19 Bioserv Analytik Und Medizinprodukte Gmbh Method for producing a test system and diagnostic method for detecting pancreatic function disorders
DE10101792B4 (en) * 2001-01-17 2004-03-18 Vivotec Biomedical Technologies Gmbh Procedure for the detection of pancreatic carcinoma or chronic pancreatitis and use of antibodies
JP2006226795A (en) * 2005-02-16 2006-08-31 Tokyo Univ Of Science Diagnostic marker of acute pancreatitis
CN111044723A (en) 2018-10-12 2020-04-21 谢鲍生物科技股份公司 Novel test kit containing trypsin-1-specific antibodies and sample preparation device
WO2023100910A1 (en) * 2021-11-30 2023-06-08 株式会社Ｌｓｉメディエンス Method for measuring elastase 1 in feces

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5925183B2 (en) * 1978-07-05 1984-06-15 ダイナボット株式会社 Method for measuring elastase-1
JP2617299B2 (en) * 1986-09-17 1997-06-04 ダイナボット 株式会社 Immunoassay method for elastase 1

Also Published As

Publication number Publication date
JPH1080272A (en) 1998-03-31
EP0547059A1 (en) 1993-06-23
DE4107765A1 (en) 1992-01-30
DK0547059T3 (en) 1996-02-19
ATE128734T1 (en) 1995-10-15
CA2088354A1 (en) 1992-01-29
GR3018483T3 (en) 1996-03-31
DE59106634D1 (en) 1995-11-09
EP0547059B1 (en) 1995-10-04
JPH05508770A (en) 1993-12-09
AU646476B2 (en) 1994-02-24
ES2080955T3 (en) 1996-02-16
WO1992002630A1 (en) 1992-02-20
CA2088354C (en) 1999-09-28

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Legal Events

Date Code Title Description
MK14 Patent ceased section 143(a) (annual fees not paid) or expired