JPS5735551A - Preparation of undecapeptide - Google Patents

Preparation of undecapeptide

Info

Publication number
JPS5735551A
JPS5735551A JP10890080A JP10890080A JPS5735551A JP S5735551 A JPS5735551 A JP S5735551A JP 10890080 A JP10890080 A JP 10890080A JP 10890080 A JP10890080 A JP 10890080A JP S5735551 A JPS5735551 A JP S5735551A
Authority
JP
Japan
Prior art keywords
undecapeptide
give
reacted
hydrazide
asparaginyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP10890080A
Other languages
Japanese (ja)
Inventor
Noboru Yanaihara
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Fujifilm RI Pharma Co Ltd
Original Assignee
Fujifilm RI Pharma Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Fujifilm RI Pharma Co Ltd filed Critical Fujifilm RI Pharma Co Ltd
Priority to JP10890080A priority Critical patent/JPS5735551A/en
Publication of JPS5735551A publication Critical patent/JPS5735551A/en
Pending legal-status Critical Current

Links

Classifications

    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Peptides Or Proteins (AREA)

Abstract

PURPOSE: To obtain undecapeptide suitable for preparing a specific antibody useful for measuring the concentration of pancreas glucagon in blood, by condensing a hydrazide compound with heptapeptide by azide method.
CONSTITUTION: Benzyloxycarbonyl-alanyl-glutaminyl-asparaginyl-phenylalanine hydrazide is reacted with isoamyl nitrite in the presence of hydrochloric acid to give an azide, which is reacted with a heptapeptide obtained by reacting tertiary butyloxycarbonyl-valyl-glutaminyl-tryptophyl-leucine hydrazide with methionyl- asparaginyl-threonine by azide method, to give an undecapeptide having a protecting group. The undecapeptide is reacted with sodium in liquid ammonia and the protecting group is removed to give the desired undecapeptide. This undecapiptide is condensed with bovine serum albumin, etc. to give an antigen, from which an antibody having high specificity can be obtained.
COPYRIGHT: (C)1982,JPO&Japio
JP10890080A 1980-08-08 1980-08-08 Preparation of undecapeptide Pending JPS5735551A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP10890080A JPS5735551A (en) 1980-08-08 1980-08-08 Preparation of undecapeptide

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP10890080A JPS5735551A (en) 1980-08-08 1980-08-08 Preparation of undecapeptide

Publications (1)

Publication Number Publication Date
JPS5735551A true JPS5735551A (en) 1982-02-26

Family

ID=14496464

Family Applications (1)

Application Number Title Priority Date Filing Date
JP10890080A Pending JPS5735551A (en) 1980-08-08 1980-08-08 Preparation of undecapeptide

Country Status (1)

Country Link
JP (1) JPS5735551A (en)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6231995A (en) * 1985-07-31 1987-02-10 明治ナシヨナル工業株式会社 Discharge lamp dual bright point lighting apparatus
JPH06223988A (en) * 1992-12-22 1994-08-12 Edwin Meabeek Ronald Apparatus and method for operation of electric lamp
US7534189B2 (en) 2005-11-17 2009-05-19 Aisin Aw Co., Ltd. Planetary gear train and driving unit having the same

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5399320A (en) * 1977-02-10 1978-08-30 Otsuka Pharmaceut Co Ltd Method for preparing aintigens
JPS5446776A (en) * 1977-09-21 1979-04-12 Takeda Chem Ind Ltd Novel peptide

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5399320A (en) * 1977-02-10 1978-08-30 Otsuka Pharmaceut Co Ltd Method for preparing aintigens
JPS5446776A (en) * 1977-09-21 1979-04-12 Takeda Chem Ind Ltd Novel peptide

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6231995A (en) * 1985-07-31 1987-02-10 明治ナシヨナル工業株式会社 Discharge lamp dual bright point lighting apparatus
JPH06223988A (en) * 1992-12-22 1994-08-12 Edwin Meabeek Ronald Apparatus and method for operation of electric lamp
US7534189B2 (en) 2005-11-17 2009-05-19 Aisin Aw Co., Ltd. Planetary gear train and driving unit having the same

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