DK0541594T3 - Cyklopentan-derivater, fremgangsmåde til fremstilling deraf samt farmaceutisk anvendelse af derivaterne - Google Patents

Cyklopentan-derivater, fremgangsmåde til fremstilling deraf samt farmaceutisk anvendelse af derivaterne

Info

Publication number
DK0541594T3
DK0541594T3 DK91912997.3T DK91912997T DK0541594T3 DK 0541594 T3 DK0541594 T3 DK 0541594T3 DK 91912997 T DK91912997 T DK 91912997T DK 0541594 T3 DK0541594 T3 DK 0541594T3
Authority
DK
Denmark
Prior art keywords
derivatives
pharmaceutical use
preparation
cyclopentane
formula
Prior art date
Application number
DK91912997.3T
Other languages
Danish (da)
English (en)
Inventor
Ulrich Dr Klar
Hartmut Dr Rehwinkel
Helmut Prof Vorbrueggen
Karl-Heinz Dr Thierauch
Peter Dr Verhallen
Original Assignee
Schering Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Ag filed Critical Schering Ag
Application granted granted Critical
Publication of DK0541594T3 publication Critical patent/DK0541594T3/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C405/00Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D215/00Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/36Sulfur atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
DK91912997.3T 1990-07-27 1991-07-22 Cyklopentan-derivater, fremgangsmåde til fremstilling deraf samt farmaceutisk anvendelse af derivaterne DK0541594T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE4024347A DE4024347A1 (de) 1990-07-27 1990-07-27 Cyclopentanderivate, verfahren zu ihrer herstellung und ihre pharmazeutische verwendung

Publications (1)

Publication Number Publication Date
DK0541594T3 true DK0541594T3 (da) 1995-10-02

Family

ID=6411402

Family Applications (1)

Application Number Title Priority Date Filing Date
DK91912997.3T DK0541594T3 (da) 1990-07-27 1991-07-22 Cyklopentan-derivater, fremgangsmåde til fremstilling deraf samt farmaceutisk anvendelse af derivaterne

Country Status (13)

Country Link
EP (1) EP0541594B1 (xx)
JP (1) JPH06502390A (xx)
AT (1) ATE122036T1 (xx)
AU (1) AU8221291A (xx)
CA (1) CA2088161A1 (xx)
DE (3) DE4024347A1 (xx)
DK (1) DK0541594T3 (xx)
ES (1) ES2074721T3 (xx)
IE (1) IE67507B1 (xx)
IL (1) IL98970A0 (xx)
PT (1) PT98464B (xx)
WO (1) WO1992002495A1 (xx)
ZA (1) ZA915905B (xx)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4036140A1 (de) * 1990-11-09 1992-05-14 Schering Ag 9-halogen-11ss-hydroxy-prostaglandinderivate, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel
AU687906B2 (en) * 1993-12-15 1998-03-05 Alcon Laboratories, Inc. Use of certain prostaglandin analogues to treat glaucoma and ocular hypertension
DE69824966T2 (de) * 1997-09-09 2005-04-07 Duke University Aromatische c16-c20-substituierte tetrahydro-prostaglandine verwendbar wie fp agoniste
CN1269785A (zh) * 1997-09-09 2000-10-11 普罗克特和甘保尔公司 用作fp激活剂的芳香族c16-c20-取代四氢前列腺素
WO1999012898A1 (en) * 1997-09-09 1999-03-18 The Procter & Gamble Company Aromatic c16-c20-substituted tetrahydro prostaglandins useful as fp agonists
US6242493B1 (en) 1998-03-13 2001-06-05 Merck Frosst Canada & Co. Carboxylic acids and acylsulfonamides, compositions containing such compounds and methods of treatment
EP1071648A2 (en) * 1998-03-13 2001-01-31 Merck Frosst Canada & Co. Carboxylic acids and acylsulfonamides, compositions containing such compounds and methods of treatment
JP4834224B2 (ja) 1999-03-05 2011-12-14 デューク ユニバーシティ C16不飽和fp−選択的プロスタグランジン類縁体
US20020172693A1 (en) 2000-03-31 2002-11-21 Delong Michell Anthony Compositions and methods for treating hair loss using non-naturally occurring prostaglandins
US20020013294A1 (en) 2000-03-31 2002-01-31 Delong Mitchell Anthony Cosmetic and pharmaceutical compositions and methods using 2-decarboxy-2-phosphinico derivatives
US7323591B2 (en) * 2006-01-10 2008-01-29 Allergan, Inc. Substituted cyclopentanes or cyclopentanones as therapeutic agents
EP2291346A2 (en) 2008-05-15 2011-03-09 Allergan, Inc. Therapeutic substituted cyclopentanes
CN102336754B (zh) * 2010-07-15 2017-04-12 浙江奥翔药业股份有限公司 恩替卡韦的合成方法及其中间体化合物

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1431561A (en) * 1973-01-31 1976-04-07 Ici Ltd Cyclopentane derivatives
IT1053781B (it) * 1974-09-25 1981-10-10 Erba C S P A Ora Farmitalia Omega nor cicloalcil 13.14 deidro prostaglandine
FR2349328A1 (fr) * 1976-04-30 1977-11-25 Roussel Uclaf Nouveaux derives de la 11-desoxy prostaglandine f2, leur procede de preparation et leur application comme medicaments
DE3126924A1 (de) * 1981-07-03 1983-01-20 Schering Ag, 1000 Berlin Und 4619 Bergkamen 9-fluor-prostaglandinderivate, verfahren zur herstellung und verwendung als arzneimittel
DE3325175A1 (de) * 1983-07-08 1985-01-17 Schering AG, 1000 Berlin und 4709 Bergkamen 11-halogen-prostanderivate, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel
DE3510978A1 (de) * 1985-03-22 1986-09-25 Schering AG, Berlin und Bergkamen, 1000 Berlin Neue 9-halogenprostaglandine, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel
HU206084B (en) * 1987-07-17 1992-08-28 Schering Ag Process for producing 9-halogen-/z/-prostaglandin derivatives and pharmaceutical compositions comprising such active ingredient
DE3923797A1 (de) * 1989-07-14 1991-01-24 Schering Ag 9-fluor-prostaglandin-derivate, verfahren zu ihrer herstellung und ihre pharmazeutische verwendung

Also Published As

Publication number Publication date
DE4024347A1 (de) 1992-01-30
IL98970A0 (en) 1992-07-15
PT98464B (pt) 1997-10-31
DE4191848D2 (de) 1993-10-07
ZA915905B (en) 1992-04-29
ES2074721T3 (es) 1995-09-16
DE59105400D1 (de) 1995-06-08
ATE122036T1 (de) 1995-05-15
EP0541594A1 (de) 1993-05-19
CA2088161A1 (en) 1992-01-28
JPH06502390A (ja) 1994-03-17
IE912654A1 (en) 1992-01-29
AU8221291A (en) 1992-03-02
PT98464A (pt) 1992-05-29
WO1992002495A1 (de) 1992-02-20
EP0541594B1 (de) 1995-05-03
IE67507B1 (en) 1996-04-03

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