DK0536235T3 - Under tryk stående aerosolpræparater - Google Patents

Under tryk stående aerosolpræparater

Info

Publication number
DK0536235T3
DK0536235T3 DK91912173.1T DK91912173T DK0536235T3 DK 0536235 T3 DK0536235 T3 DK 0536235T3 DK 91912173 T DK91912173 T DK 91912173T DK 0536235 T3 DK0536235 T3 DK 0536235T3
Authority
DK
Denmark
Prior art keywords
surfactant
propellant
pressurized aerosol
aerosol preparations
medicament
Prior art date
Application number
DK91912173.1T
Other languages
English (en)
Inventor
Asit Somani
Clive Booles
Original Assignee
Fisons Plc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB909014527A external-priority patent/GB9014527D0/en
Priority claimed from GB909014526A external-priority patent/GB9014526D0/en
Priority claimed from GB909023953A external-priority patent/GB9023953D0/en
Application filed by Fisons Plc filed Critical Fisons Plc
Application granted granted Critical
Publication of DK0536235T3 publication Critical patent/DK0536235T3/da

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/007Pulmonary tract; Aromatherapy
    • A61K9/0073Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/008Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy comprising drug dissolved or suspended in liquid propellant for inhalation via a pressurized metered dose inhaler [MDI]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/10Dispersions; Emulsions
    • A61K9/12Aerosols; Foams
    • A61K9/124Aerosols; Foams characterised by the propellant

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Dispersion Chemistry (AREA)
  • Otolaryngology (AREA)
  • Pulmonology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Medicinal Preparation (AREA)
  • Cosmetics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Containers And Packaging Bodies Having A Special Means To Remove Contents (AREA)
  • Fertilizers (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
DK91912173.1T 1990-06-29 1991-06-25 Under tryk stående aerosolpræparater DK0536235T3 (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB909014527A GB9014527D0 (en) 1990-06-29 1990-06-29 Aerosol formulation
GB909014526A GB9014526D0 (en) 1990-06-29 1990-06-29 Aerosol formulation
GB909023953A GB9023953D0 (en) 1990-11-03 1990-11-03 Pharmaceutical composition

Publications (1)

Publication Number Publication Date
DK0536235T3 true DK0536235T3 (da) 1997-04-14

Family

ID=27265168

Family Applications (1)

Application Number Title Priority Date Filing Date
DK91912173.1T DK0536235T3 (da) 1990-06-29 1991-06-25 Under tryk stående aerosolpræparater

Country Status (21)

Country Link
US (1) US5846521A (da)
EP (1) EP0536235B1 (da)
JP (1) JP2854974B2 (da)
AT (1) ATE147973T1 (da)
AU (1) AU8055691A (da)
BR (1) BR9106595A (da)
CA (1) CA2085884C (da)
CZ (1) CZ392592A3 (da)
DE (1) DE69124374T2 (da)
DK (1) DK0536235T3 (da)
ES (1) ES2096653T3 (da)
FI (1) FI925852A (da)
GR (1) GR3023065T3 (da)
HU (1) HUT63554A (da)
IE (1) IE912220A1 (da)
MX (1) MX9100008A (da)
NO (1) NO924954L (da)
NZ (1) NZ238746A (da)
PT (1) PT98133A (da)
SK (1) SK392592A3 (da)
WO (1) WO1992000061A1 (da)

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US5776434A (en) * 1988-12-06 1998-07-07 Riker Laboratories, Inc. Medicinal aerosol formulations
US5785952A (en) * 1990-11-09 1998-07-28 Glaxo Group Limited Aerosol medicament formulation having a surface coating of surfactant
US5474759A (en) * 1991-06-10 1995-12-12 Schering Corporation Non-chlorofluorocarbon aerosol formulations
ATE203900T1 (de) * 1991-06-10 2001-08-15 Schering Corp Fluorchlorkohlenwasserstofffreie aerosolformulierungen
IL104068A (en) * 1991-12-12 1998-10-30 Glaxo Group Ltd Pharmaceutical preparations in a spray without surfactant containing 1, 1, 1, 2 tetrafluoroethane or 1,1,2,3,3 petafluor N propane as propellant
US5916540A (en) 1994-10-24 1999-06-29 Glaxo Group Limited Aerosol formulations containing P134A and/or P227 and particulate medicament
DE69227257T2 (de) 1991-12-12 1999-03-25 Glaxo Group Ltd Arzneimittel
US7101534B1 (en) 1991-12-18 2006-09-05 3M Innovative Properties Company Suspension aerosol formulations
US5376359A (en) * 1992-07-07 1994-12-27 Glaxo, Inc. Method of stabilizing aerosol formulations
MX9304585A (es) * 1992-07-31 1994-03-31 Glaxo Group Ltd Formulacion farmaceutica en aerosol, lata adecuada para liberar la formulacion e inhalador de dosis dosificada que comprende la lata.
EP0689424B1 (en) * 1993-03-17 1998-10-14 Minnesota Mining And Manufacturing Company Aerosol formulation containing an ester-, amide-, or mercaptoester-derived dispersing aid
JPH08507792A (ja) * 1993-03-17 1996-08-20 ミネソタ マイニング アンド マニュファクチャリング カンパニー ジオール−二酸から誘導される分散助剤を含むエーロゾル配合物
US5593661A (en) * 1993-03-29 1997-01-14 Henry; Richard A. Lidocaine aerosol anaesthetic
PT731688E (pt) * 1993-12-02 2003-07-31 Abbott Lab Formulacoes de farmacos em aerossol para utilizacao com propulsores sem cfc
US5502076A (en) * 1994-03-08 1996-03-26 Hoffmann-La Roche Inc. Dispersing agents for use with hydrofluoroalkane propellants
US5635159A (en) * 1994-08-26 1997-06-03 Abbott Laboratories Aerosol drug formulations containing polyglycolyzed glycerides
US5635161A (en) * 1995-06-07 1997-06-03 Abbott Laboratories Aerosol drug formulations containing vegetable oils
US6652837B1 (en) 1996-05-24 2003-11-25 Massachusetts Institute Of Technology Preparation of novel particles for inhalation
US5874064A (en) 1996-05-24 1999-02-23 Massachusetts Institute Of Technology Aerodynamically light particles for pulmonary drug delivery
GB9616237D0 (en) 1996-08-01 1996-09-11 Norton Healthcare Ltd Aerosol formulations
US6461591B1 (en) 1997-02-05 2002-10-08 Jago Research Ag Medical aerosol formulations
US6433040B1 (en) 1997-09-29 2002-08-13 Inhale Therapeutic Systems, Inc. Stabilized bioactive preparations and methods of use
US20060165606A1 (en) 1997-09-29 2006-07-27 Nektar Therapeutics Pulmonary delivery particles comprising water insoluble or crystalline active agents
US6565885B1 (en) 1997-09-29 2003-05-20 Inhale Therapeutic Systems, Inc. Methods of spray drying pharmaceutical compositions
US6309623B1 (en) 1997-09-29 2001-10-30 Inhale Therapeutic Systems, Inc. Stabilized preparations for use in metered dose inhalers
GB9805938D0 (en) 1998-03-19 1998-05-13 Glaxo Group Ltd Valve for aerosol container
GB9807232D0 (en) 1998-04-03 1998-06-03 Univ Cardiff Aerosol composition
US6451285B2 (en) 1998-06-19 2002-09-17 Baker Norton Pharmaceuticals, Inc. Suspension aerosol formulations containing formoterol fumarate and a fluoroalkane propellant
JP4570251B2 (ja) 1998-07-24 2010-10-27 ヤゴテック アーゲー 医薬用エーロゾル製剤
NZ509489A (en) * 1998-08-04 2002-10-25 Jago Res A Medicinal aerosol formulations comprising cromoglycic acid and/or nedocromil
US6749835B1 (en) 1999-08-25 2004-06-15 Advanced Inhalation Research, Inc. Formulation for spray-drying large porous particles
US7678364B2 (en) 1999-08-25 2010-03-16 Alkermes, Inc. Particles for inhalation having sustained release properties
US7871598B1 (en) 2000-05-10 2011-01-18 Novartis Ag Stable metal ion-lipid powdered pharmaceutical compositions for drug delivery and methods of use
US8404217B2 (en) 2000-05-10 2013-03-26 Novartis Ag Formulation for pulmonary administration of antifungal agents, and associated methods of manufacture and use
US6451287B1 (en) 2000-05-26 2002-09-17 Smithkline Beecham Corporation Fluorinated copolymer surfactants and use thereof in aerosol compositions
JP2004509159A (ja) 2000-09-22 2004-03-25 グラクソ グループ リミテッド 新規なアルカン酸誘導体
EP1345629A2 (en) 2000-12-29 2003-09-24 Advanced Inhalation Research, Inc. Particles for inhalation having sustained release properties
GB0208742D0 (en) 2002-04-17 2002-05-29 Bradford Particle Design Ltd Particulate materials
GB0125127D0 (en) 2001-10-19 2001-12-12 Glaxo Group Ltd Compounds
ATE508735T1 (de) 2001-12-19 2011-05-15 Novartis Ag Pulmonale verabreichung von aminoglykosiden
EP1458357B1 (en) * 2001-12-21 2009-03-04 3M Innovative Properties Company Medicinal aerosol compositions with a functionalized polyethyleneglycol excipient
EP1474376A1 (en) 2002-02-13 2004-11-10 Glaxo Group Limited Carboxylic acid compounds for use as surfactants
GB0205327D0 (en) * 2002-03-06 2002-04-17 Glaxo Group Ltd compounds
EP2275479A1 (en) 2003-08-11 2011-01-19 Glaxo Group Limited Pharmaceutical metered dose inhaler and methods relating thereto
CN1874756B (zh) 2003-08-29 2012-02-29 葛兰素集团有限公司 药用计量剂量吸入器和其相关方法
JP5825757B2 (ja) 2007-02-11 2015-12-02 マップ・ファーマシューティカルズ・インコーポレイテッド 副作用プロファイルを最小限にしながら片頭痛の迅速な緩和を可能にするdheの治療上の投与方法
GB0712454D0 (en) 2007-06-27 2007-08-08 Generics Uk Ltd Pharmaceutical compositions
EP3174522A1 (en) 2014-07-29 2017-06-07 3M Innovative Properties Company Method of preparing a pharmaceutical composition

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL7708731A (nl) * 1976-08-13 1978-02-15 Montedison Spa Werkwijze voor de bereiding van nieuwe drijf- middelsamenstellingen voor aerosolen.
CA1136547A (en) * 1979-03-08 1982-11-30 Song-Ling Lin Aerosol anesthetic compositions
GB8432063D0 (en) * 1984-12-19 1985-01-30 Riker Laboratories Inc Physically modified steroids
EP0309519B1 (en) * 1987-04-09 1992-07-08 FISONS plc Pharmaceutical compositions containing pentamidine
US5225183A (en) * 1988-12-06 1993-07-06 Riker Laboratories, Inc. Medicinal aerosol formulations
GB8828477D0 (en) * 1988-12-06 1989-01-05 Riker Laboratories Inc Medical aerosol formulations
GB8828544D0 (en) * 1988-12-07 1989-01-11 Ici Plc Chemical process
DE3905726A1 (de) * 1989-02-24 1990-08-30 Hoechst Ag Druckgaspackung und treibmittel fuer aerosole
GB8908250D0 (en) * 1989-04-12 1989-05-24 Fisons Plc Formulations
US5653962A (en) * 1991-12-12 1997-08-05 Glaxo Group Limited Aerosol formulations containing P134a and particulate medicaments
US5658549A (en) * 1991-12-12 1997-08-19 Glaxo Group Limited Aerosol formulations containing propellant 134a and fluticasone propionate

Also Published As

Publication number Publication date
NO924954D0 (no) 1992-12-21
ATE147973T1 (de) 1997-02-15
DE69124374D1 (de) 1997-03-06
FI925852A0 (fi) 1992-12-23
ES2096653T3 (es) 1997-03-16
PT98133A (pt) 1992-04-30
CA2085884C (en) 2001-12-04
FI925852A (fi) 1992-12-23
GR3023065T3 (en) 1997-07-30
EP0536235A1 (en) 1993-04-14
NZ238746A (en) 1992-10-28
NO924954L (no) 1992-12-21
HUT63554A (en) 1993-09-28
MX9100008A (es) 1992-02-03
DE69124374T2 (de) 1997-06-19
JPH05507712A (ja) 1993-11-04
WO1992000061A1 (en) 1992-01-09
IE912220A1 (en) 1992-01-01
EP0536235B1 (en) 1997-01-22
HU9204098D0 (en) 1993-03-29
US5846521A (en) 1998-12-08
BR9106595A (pt) 1993-04-20
CZ392592A3 (en) 1993-05-12
JP2854974B2 (ja) 1999-02-10
SK392592A3 (en) 1994-07-06
CA2085884A1 (en) 1991-12-30
AU8055691A (en) 1992-01-23

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