DK0535060T3 - Antifungisk polypeptid samt fremgangsmåde til dets fremstilling - Google Patents

Antifungisk polypeptid samt fremgangsmåde til dets fremstilling

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Publication number
DK0535060T3
DK0535060T3 DK91911239.1T DK91911239T DK0535060T3 DK 0535060 T3 DK0535060 T3 DK 0535060T3 DK 91911239 T DK91911239 T DK 91911239T DK 0535060 T3 DK0535060 T3 DK 0535060T3
Authority
DK
Denmark
Prior art keywords
lys
cys
tyr
gly
ala
Prior art date
Application number
DK91911239.1T
Other languages
English (en)
Inventor
Burkhard Sachse
Peter Eckes
Norbert Ulbrich
Rolf Hilgenfeld
Heinz Haenel
Peter Braun
Joachim Wink
Juergen Logemann
Jozef Schell
Original Assignee
Hoechst Schering Agrevo Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Schering Agrevo Gmbh filed Critical Hoechst Schering Agrevo Gmbh
Application granted granted Critical
Publication of DK0535060T3 publication Critical patent/DK0535060T3/da

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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N63/00Biocides, pest repellants or attractants, or plant growth regulators containing microorganisms, viruses, microbial fungi, animals or substances produced by, or obtained from, microorganisms, viruses, microbial fungi or animals, e.g. enzymes or fermentates
    • A01N63/50Isolated enzymes; Isolated proteins
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/37Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from fungi
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8241Phenotypically and genetically modified plants via recombinant DNA technology
    • C12N15/8261Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield
    • C12N15/8271Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield for stress resistance, e.g. heavy metal resistance
    • C12N15/8279Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield for stress resistance, e.g. heavy metal resistance for biotic stress resistance, pathogen resistance, disease resistance
    • C12N15/8282Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield for stress resistance, e.g. heavy metal resistance for biotic stress resistance, pathogen resistance, disease resistance for fungal resistance
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S47/00Plant husbandry
    • Y10S47/01Methods of plant-breeding and including chromosome multiplication
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/82Proteins from microorganisms
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/82Proteins from microorganisms
    • Y10S530/823Lower fungi, e.g. mold

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Zoology (AREA)
  • Organic Chemistry (AREA)
  • Biotechnology (AREA)
  • Wood Science & Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Microbiology (AREA)
  • Plant Pathology (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Pest Control & Pesticides (AREA)
  • Medicinal Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Agronomy & Crop Science (AREA)
  • Mycology (AREA)
  • Virology (AREA)
  • Dentistry (AREA)
  • Environmental Sciences (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DK91911239.1T 1990-06-15 1991-06-12 Antifungisk polypeptid samt fremgangsmåde til dets fremstilling DK0535060T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE4019105 1990-06-15
DE4107140 1991-03-06

Publications (1)

Publication Number Publication Date
DK0535060T3 true DK0535060T3 (da) 1995-07-17

Family

ID=25894160

Family Applications (1)

Application Number Title Priority Date Filing Date
DK91911239.1T DK0535060T3 (da) 1990-06-15 1991-06-12 Antifungisk polypeptid samt fremgangsmåde til dets fremstilling

Country Status (9)

Country Link
US (3) US5421839A (da)
EP (1) EP0535060B1 (da)
JP (1) JP3370090B2 (da)
AT (1) ATE118788T1 (da)
DE (1) DE59104720D1 (da)
DK (1) DK0535060T3 (da)
ES (1) ES2071319T3 (da)
GR (1) GR3015741T3 (da)
WO (1) WO1991019738A1 (da)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5421839A (en) * 1990-06-15 1995-06-06 Hoechst Aktiengesellschaft Antifungal polypeptide and process for its production
JPH04234399A (ja) * 1990-12-28 1992-08-24 Kazuyasu Nakatani 抗真菌活性ペプチド
DK91192D0 (da) * 1992-07-10 1992-07-10 Novo Nordisk As Protein
DE4233337A1 (de) * 1992-10-05 1994-04-07 Bayer Ag Mikrobizide Mittel
USRE39238E1 (en) 1992-10-09 2006-08-15 Max-Planck-Gesellschaft zür Forderung der Wissenschaften e.V. Transgenic pathogen-resistant organism
DE4234131C2 (de) 1992-10-09 1995-08-24 Max Planck Gesellschaft Transgener pathogen-resistenter Organismus
GB9310238D0 (en) * 1993-05-18 1993-07-14 Mini Agriculture & Fisheries Method,agents and kits for detection of organic agents
US6077995A (en) * 1996-03-21 2000-06-20 The United States Of America As Represented By The Secretary Of Agriculture Fungal gene encoding resistance to the phytotoxin cercosporin
US5773696A (en) 1996-03-29 1998-06-30 Monsanto Company Antifungal polypeptide and methods for controlling plant pathogenic fungi
WO1998000166A1 (en) 1996-07-03 1998-01-08 Merial, Inc. Recombinant canine adenovirus (cav) containing exogenous dna
US6121436A (en) * 1996-12-13 2000-09-19 Monsanto Company Antifungal polypeptide and methods for controlling plant pathogenic fungi
FR2766207B1 (fr) * 1997-07-11 2000-12-08 Rhone Poulenc Agrochimie Gene chimere codant pour la drosomycine, vecteur le contenant pour la transformation des cellules vegetales et plantes transformees obtenues resistantes aux maladies
FR2766206A1 (fr) * 1997-07-11 1999-01-22 Rhone Poulenc Agrochimie Gene chimere codant pour la drosomycine, vecteur le contenant pour la transformation des cellules vegetales et plantes transformees obtenues resistantes aux maladies
US6015941A (en) * 1997-10-31 2000-01-18 Pioneer Hi-Bred International, Inc. Peptide derivatives of tachyplesin having antimicrobial activity
AU772335B2 (en) * 1998-10-30 2004-04-22 Interlink Biotechnologies Llc Peptides with enhanced stability to protease degradation
JP2002530274A (ja) * 1998-10-30 2002-09-17 インターリンク・バイオテクノロジーズ・リミテッド・ライアビリティ・カンパニー プロテアーゼ分解に対する安定性の高いペプチド
US6855865B2 (en) * 1999-05-07 2005-02-15 E.I. Du Pont De Nemours And Company Nucleic acids encoding plant defensins and methods of use thereof
EP1191948A2 (en) * 1999-06-11 2002-04-03 Neorx Corporation High dose radionuclide complexes for bone marrow suppression
US7094885B2 (en) * 1999-07-11 2006-08-22 Neorx Corporation Skeletal-targeted radiation to treat bone-associated pathologies
WO2002062398A2 (en) 2001-01-08 2002-08-15 Neorx Corporation Radioactively labelled conjugates of phosphonates
AU2002341503A1 (en) * 2001-05-04 2002-11-18 Novozymes A/S Antimicrobial polypeptide from aspergillus niger
AU2002322388A1 (en) 2001-06-22 2003-01-08 E.I. Du Pont De Nemours And Company Defensin polynucleotides and methods of use
EP1458416A1 (en) 2001-12-13 2004-09-22 Dow Global Technologies Inc. Treatment of osteomyelitis with radiopharmaceuticals
WO2003089455A2 (en) * 2002-04-22 2003-10-30 Dow Global Technologies Inc. Low-cost production of peptides
CN105658663A (zh) 2013-04-30 2016-06-08 唐纳德丹佛斯植物科学中心 抗真菌植物蛋白质、肽和使用方法
WO2024137918A1 (en) 2022-12-21 2024-06-27 Donald Danforth Plant Science Center Antimicrobial peptides and modifications thereof

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3104204A (en) * 1960-07-11 1963-09-17 Michigan State Alpha sarcin
US4394443A (en) * 1980-12-18 1983-07-19 Yale University Method for cloning genes
JPH02502513A (ja) * 1986-07-25 1990-08-16 ザ ボード オブ スーパーバイザーズ オブ ルイジアナ ステート ユニバーシティ アンド アグリカルチュラル アンド メカニカル カレッジ 病気抵抗体及び害虫抵抗体を植物に組み込む方法並びに植物に組み込まれ該抵抗体の暗号に対応する新規な遺伝子
US5049500A (en) * 1987-01-13 1991-09-17 E. I. Du Pont De Nemours Pollen-mediated gene transformation in plants
EP0275069A3 (en) * 1987-01-13 1990-04-25 DNA PLANT TECHNOLOGY CORPORATION (under the laws of the state of Delaware) Pollen-mediated gene transformation in plants
NZ224470A (en) * 1987-05-05 1991-06-25 Sandoz Ltd Method of transforming plant cell material; plant cell material and plants
ES2074999T3 (es) * 1987-05-20 1995-10-01 Ciba Geigy Ag Plantas de zea mays y plantas de zea mays transgenicas regeneradas de protoplastos o celulas derivadas de protoplastos.
EP0675960A1 (en) * 1987-11-02 1995-10-11 Louisiana State University and Agricultural and Mechanical College Plants genetically enhanced for disease resistance
DK604687D0 (da) * 1987-11-17 1987-11-17 Novo Industri As Praeparater
FI890917A (fi) * 1988-03-02 1989-09-03 Eidgenoess Tech Hochschule Foerfarande foer framstaellning av transgena vaexter.
US5421839A (en) * 1990-06-15 1995-06-06 Hoechst Aktiengesellschaft Antifungal polypeptide and process for its production

Also Published As

Publication number Publication date
US5824874A (en) 1998-10-20
GR3015741T3 (en) 1995-07-31
ES2071319T3 (es) 1995-06-16
US5589624A (en) 1996-12-31
WO1991019738A1 (de) 1991-12-26
JPH06500074A (ja) 1994-01-06
EP0535060A1 (de) 1993-04-07
JP3370090B2 (ja) 2003-01-27
EP0535060B1 (de) 1995-02-22
ATE118788T1 (de) 1995-03-15
DE59104720D1 (de) 1995-03-30
US5421839A (en) 1995-06-06

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