DK0530447T3 - Fremgangsmåde til rensning af IgG-monoklonale antistoffer - Google Patents

Fremgangsmåde til rensning af IgG-monoklonale antistoffer

Info

Publication number
DK0530447T3
DK0530447T3 DK92108912.4T DK92108912T DK0530447T3 DK 0530447 T3 DK0530447 T3 DK 0530447T3 DK 92108912 T DK92108912 T DK 92108912T DK 0530447 T3 DK0530447 T3 DK 0530447T3
Authority
DK
Denmark
Prior art keywords
monoclonal antibodies
igg monoclonal
purifying igg
purifying
immunotherapy
Prior art date
Application number
DK92108912.4T
Other languages
Danish (da)
English (en)
Inventor
Norbert Dr Kothe
Dieter Dr Rudnick
Ulf Dr Bethke
Michael Dr Kloft
Detlef Dr Rohm
Original Assignee
Biotest Pharma Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biotest Pharma Gmbh filed Critical Biotest Pharma Gmbh
Application granted granted Critical
Publication of DK0530447T3 publication Critical patent/DK0530447T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/06—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies from serum
    • C07K16/065—Purification, fragmentation

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
DK92108912.4T 1991-06-08 1992-05-27 Fremgangsmåde til rensning af IgG-monoklonale antistoffer DK0530447T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE4118912A DE4118912C1 (enExample) 1991-06-08 1991-06-08

Publications (1)

Publication Number Publication Date
DK0530447T3 true DK0530447T3 (da) 1998-01-12

Family

ID=6433511

Family Applications (1)

Application Number Title Priority Date Filing Date
DK92108912.4T DK0530447T3 (da) 1991-06-08 1992-05-27 Fremgangsmåde til rensning af IgG-monoklonale antistoffer

Country Status (7)

Country Link
EP (1) EP0530447B1 (enExample)
JP (1) JP2644946B2 (enExample)
AT (1) ATE159532T1 (enExample)
DE (2) DE4118912C1 (enExample)
DK (1) DK0530447T3 (enExample)
ES (1) ES2108059T3 (enExample)
GR (1) GR3025603T3 (enExample)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2706466B1 (fr) * 1993-06-14 1995-08-25 Aetsrn Concentré d'immunoglobulines G à usage thérapeutique et procédé de production dudit concentré.
IL121900A (en) * 1997-10-07 2001-12-23 Omrix Biopharmaceuticals Ltd A method for the purification of immunoglobulins
ES2421736T3 (es) * 1998-06-09 2013-09-05 Csl Behring Ag Procedimiento para la preparación de inmunoglobulinas para administración intravenosa y otros productos inmunoglobulínicos
TR200100303T2 (tr) 1998-06-09 2001-06-21 Statens Serum Institut Damardan uygulanacak immünoglobülinler üretmek için yöntem ve başka immünoglobülin ürünleri.
SE0001128D0 (sv) * 2000-03-30 2000-03-30 Amersham Pharm Biotech Ab A method of producing IgG
EP1614693A4 (en) * 2003-03-31 2006-07-19 Kirin Brewery Purification of a human monoclonal antibody and human polyclonal antibody
EP1532983A1 (en) 2003-11-18 2005-05-25 ZLB Bioplasma AG Immunoglobulin preparations having increased stability
TWI391399B (zh) 2005-05-25 2013-04-01 Hoffmann La Roche 測定溶離多肽之鹽濃度之方法
KR101226353B1 (ko) 2007-06-01 2013-01-24 에프. 호프만-라 로슈 아게 면역글로불린 정제
AR067536A1 (es) 2007-07-17 2009-10-14 Hoffmann La Roche Metodo para obtener una eritropoyetina mono-pegilada en una forma sustancialmente homogenea
AR067537A1 (es) 2007-07-17 2009-10-14 Hoffmann La Roche Purificacion de polipeptidos pegilados
WO2009058769A1 (en) * 2007-10-30 2009-05-07 Schering Corporation Purification of antibodies containing hydrophobic variants
AU2009331897A1 (en) 2008-12-22 2010-07-01 F. Hoffmann-La Roche Ag Immunoglobulin purification
TR201903403T4 (tr) 2010-02-04 2019-04-22 Csl Behring Ag İmmünoglobulin preparatı.
US20130131318A1 (en) * 2010-02-12 2013-05-23 Diderik Reinder Kremer Single unit antibody purification
EP2361636A1 (en) 2010-02-26 2011-08-31 CSL Behring AG Immunoglobulin preparation and storage system for an immunoglobulin preparation
RU2566267C2 (ru) 2010-09-14 2015-10-20 Ф. Хоффманн-Ля Рош Аг Способ очистки пегилированного эритропоэтина
AU2011325341B2 (en) * 2010-11-01 2015-12-17 Dpx Holdings B.V. Single unit ion exchange chromatography antibody purification
WO2013026803A1 (en) 2011-08-25 2013-02-28 F. Hoffmann-La Roche Ag Cation and anion exchange chromatography method
EP2596812B1 (de) 2011-11-22 2015-06-10 Heraeus Medical GmbH Sterilisation von polymerisierbaren Monomeren
ES2785375T3 (es) 2014-03-11 2020-10-06 Green Cross Holdings Corp Procedimiento de purificación de inmunoglobulina
US12144861B2 (en) 2014-12-03 2024-11-19 Csl Behring Ag Pharmaceutical product with increased stability comprising immunoglobulins
KR102820834B1 (ko) 2016-07-15 2025-06-13 에프. 호프만-라 로슈 아게 Ｐｅｇ화 에리트로포이에틴을 정제하기 위한 방법
MX2021008983A (es) * 2019-01-30 2021-09-08 Amgen Inc Atributos de aflibercept y metodos de caracterizacion y modificacion de los mismos.

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4469630A (en) * 1983-11-25 1984-09-04 J. T. Baker Chemical Co. Purification of monoclonal antibodies
US4743680A (en) * 1985-02-01 1988-05-10 New York University Method for purifying antihemophilic factor
DE3640513A1 (de) * 1986-11-27 1988-06-09 Biotest Pharma Gmbh Verfahren zur herstellung eines virussicheren, lagerstabilen und intravenoes vertraeglichen immunglobulin-g-praeparates
DE3641115A1 (de) * 1986-12-02 1988-06-16 Lentia Gmbh Verfahren zur herstellung eines intravenoes anwendbaren und in fluessiger form stabilen immunglobulins
CA1323567C (en) * 1987-10-05 1993-10-26 Gene R. Nathans Method for purification of antibodies
US5118796A (en) * 1987-12-09 1992-06-02 Centocor, Incorporated Efficient large-scale purification of immunoglobulins and derivatives
CA2005600A1 (en) * 1988-12-20 1990-06-20 Cal-Henrik Heldin Endothelial cell growth factor

Also Published As

Publication number Publication date
EP0530447A3 (en) 1993-08-18
EP0530447A2 (de) 1993-03-10
GR3025603T3 (en) 1998-03-31
JP2644946B2 (ja) 1997-08-25
DE59208982D1 (de) 1997-11-27
EP0530447B1 (de) 1997-10-22
JPH07267997A (ja) 1995-10-17
ATE159532T1 (de) 1997-11-15
ES2108059T3 (es) 1997-12-16
DE4118912C1 (enExample) 1992-07-02

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