GR3025603T3 - Process for purifying IgG monoclonal antibodies - Google Patents

Process for purifying IgG monoclonal antibodies

Info

Publication number
GR3025603T3
GR3025603T3 GR970403248T GR970403248T GR3025603T3 GR 3025603 T3 GR3025603 T3 GR 3025603T3 GR 970403248 T GR970403248 T GR 970403248T GR 970403248 T GR970403248 T GR 970403248T GR 3025603 T3 GR3025603 T3 GR 3025603T3
Authority
GR
Greece
Prior art keywords
monoclonal antibodies
igg monoclonal
purifying igg
purifying
immunotherapy
Prior art date
Application number
GR970403248T
Other languages
English (en)
Inventor
Norbert Dr Kothe
Dieter Dr Rudnick
Detlef Dr Rohm
Ulf Dr Bethke
Michael Dr Kloft
Original Assignee
Biotest Pharma Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biotest Pharma Gmbh filed Critical Biotest Pharma Gmbh
Publication of GR3025603T3 publication Critical patent/GR3025603T3/el

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/06—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies from serum
    • C07K16/065—Purification, fragmentation

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
GR970403248T 1991-06-08 1997-12-05 Process for purifying IgG monoclonal antibodies GR3025603T3 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE4118912A DE4118912C1 (el) 1991-06-08 1991-06-08

Publications (1)

Publication Number Publication Date
GR3025603T3 true GR3025603T3 (en) 1998-03-31

Family

ID=6433511

Family Applications (1)

Application Number Title Priority Date Filing Date
GR970403248T GR3025603T3 (en) 1991-06-08 1997-12-05 Process for purifying IgG monoclonal antibodies

Country Status (7)

Country Link
EP (1) EP0530447B1 (el)
JP (1) JP2644946B2 (el)
AT (1) ATE159532T1 (el)
DE (2) DE4118912C1 (el)
DK (1) DK0530447T3 (el)
ES (1) ES2108059T3 (el)
GR (1) GR3025603T3 (el)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2706466B1 (fr) * 1993-06-14 1995-08-25 Aetsrn Concentré d'immunoglobulines G à usage thérapeutique et procédé de production dudit concentré.
IL121900A (en) * 1997-10-07 2001-12-23 Omrix Biopharmaceuticals Ltd A method for the purification of immunoglobulins
AU753468B2 (en) * 1998-06-09 2002-10-17 Csl Behring Ag Process for producing immunoglobulins for intravenous administration and other immunoglobulin products
DK2270044T3 (en) 1998-06-09 2015-01-26 Csl Behring Ag Liquid immunoglobulin G (IgG) product
SE0001128D0 (sv) * 2000-03-30 2000-03-30 Amersham Pharm Biotech Ab A method of producing IgG
JPWO2004087761A1 (ja) * 2003-03-31 2006-07-27 麒麟麦酒株式会社 ヒトモノクローナル抗体およびヒトポリクローナル抗体の精製
EP1532983A1 (en) 2003-11-18 2005-05-25 ZLB Bioplasma AG Immunoglobulin preparations having increased stability
TWI391399B (zh) 2005-05-25 2013-04-01 Hoffmann La Roche 測定溶離多肽之鹽濃度之方法
JP5064558B2 (ja) 2007-06-01 2012-10-31 エフ．ホフマン−ラ ロシュ アーゲー 免疫グロブリン精製
AR067536A1 (es) 2007-07-17 2009-10-14 Hoffmann La Roche Metodo para obtener una eritropoyetina mono-pegilada en una forma sustancialmente homogenea
CL2008002053A1 (es) 2007-07-17 2009-05-22 Hoffmann La Roche Metodo para la purificacion de una eritropoyetina monopeguilada (epompeg) que consiste en proporcionar una solucion que contiene eritropoyetina mono, poli y no peguilada y hacerla pasar por dos pasos de cromatografia de intercambio cationico y metodo para producir epo mpeg que incluye metodo de purificacion.
WO2009058769A1 (en) * 2007-10-30 2009-05-07 Schering Corporation Purification of antibodies containing hydrophobic variants
JP2012513425A (ja) 2008-12-22 2012-06-14 エフ．ホフマン−ラ ロシュ アーゲー 免疫グロブリンの精製
CA2788863C (en) 2010-02-04 2020-07-07 Reinhard Franz Bolli Immunoglobulin preparation
AU2011214361C1 (en) * 2010-02-12 2016-01-14 Dpx Holdings B.V. Single unit antibody purification
EP2361636A1 (en) 2010-02-26 2011-08-31 CSL Behring AG Immunoglobulin preparation and storage system for an immunoglobulin preparation
RU2566267C2 (ru) 2010-09-14 2015-10-20 Ф. Хоффманн-Ля Рош Аг Способ очистки пегилированного эритропоэтина
CN103189390A (zh) * 2010-11-01 2013-07-03 帝斯曼知识产权资产管理有限公司 单一单元离子交换色谱抗体纯化
BR112014004463A2 (pt) 2011-08-25 2017-03-28 Hoffmann La Roche método de cromatografia de troca de cátion e de ânion
EP2596812B1 (de) 2011-11-22 2015-06-10 Heraeus Medical GmbH Sterilisation von polymerisierbaren Monomeren
CA2941230C (en) 2014-03-11 2020-08-25 Green Cross Holdings Corporation Method for purifying immunoglobulin
CA3027143A1 (en) 2016-07-15 2018-01-18 F. Hoffmann-La Roche Ag Method for purifying pegylated erythropoietin

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4469630A (en) * 1983-11-25 1984-09-04 J. T. Baker Chemical Co. Purification of monoclonal antibodies
US4743680A (en) * 1985-02-01 1988-05-10 New York University Method for purifying antihemophilic factor
DE3640513A1 (de) * 1986-11-27 1988-06-09 Biotest Pharma Gmbh Verfahren zur herstellung eines virussicheren, lagerstabilen und intravenoes vertraeglichen immunglobulin-g-praeparates
DE3641115A1 (de) * 1986-12-02 1988-06-16 Lentia Gmbh Verfahren zur herstellung eines intravenoes anwendbaren und in fluessiger form stabilen immunglobulins
CA1323567C (en) * 1987-10-05 1993-10-26 Gene R. Nathans Method for purification of antibodies
US5118796A (en) * 1987-12-09 1992-06-02 Centocor, Incorporated Efficient large-scale purification of immunoglobulins and derivatives
CA2005600A1 (en) * 1988-12-20 1990-06-20 Cal-Henrik Heldin Endothelial cell growth factor

Also Published As

Publication number Publication date
DE59208982D1 (de) 1997-11-27
ES2108059T3 (es) 1997-12-16
JP2644946B2 (ja) 1997-08-25
EP0530447A3 (en) 1993-08-18
DE4118912C1 (el) 1992-07-02
DK0530447T3 (da) 1998-01-12
EP0530447A2 (de) 1993-03-10
JPH07267997A (ja) 1995-10-17
EP0530447B1 (de) 1997-10-22
ATE159532T1 (de) 1997-11-15

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