AU2124692A - A process for the purification of factor xiii, monoclonal antibodies against factor xiiia, the preparation and use thereof - Google Patents

A process for the purification of factor xiii, monoclonal antibodies against factor xiiia, the preparation and use thereof

Info

Publication number
AU2124692A
AU2124692A AU21246/92A AU2124692A AU2124692A AU 2124692 A AU2124692 A AU 2124692A AU 21246/92 A AU21246/92 A AU 21246/92A AU 2124692 A AU2124692 A AU 2124692A AU 2124692 A AU2124692 A AU 2124692A
Authority
AU
Australia
Prior art keywords
purification
preparation
monoclonal antibodies
antibodies against
factor
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
AU21246/92A
Other versions
AU649868B2 (en
Inventor
Johann Hock
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
CSL BEHRING GmbH
Original Assignee
CSL BEHRING GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by CSL BEHRING GmbH filed Critical CSL BEHRING GmbH
Publication of AU2124692A publication Critical patent/AU2124692A/en
Application granted granted Critical
Publication of AU649868B2 publication Critical patent/AU649868B2/en
Assigned to CENTEON PHARMA GMBH reassignment CENTEON PHARMA GMBH Alteration of Name(s) in Register under S187 Assignors: BEHRINGWERKE AKTIENGESELLSCHAFT
Assigned to AVENTIS BEHRING GMBH reassignment AVENTIS BEHRING GMBH Request to Amend Deed and Register Assignors: CENTEON PHARMA GMBH
Assigned to ZLB BEHRING GMBH reassignment ZLB BEHRING GMBH Request to Amend Deed and Register Assignors: AVENTIS BEHRING GMBH
Assigned to CSL BEHRING GMBH reassignment CSL BEHRING GMBH Request to Amend Deed and Register Assignors: ZLB BEHRING GMBH
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/1025—Acyltransferases (2.3)
    • C12N9/104—Aminoacyltransferases (2.3.2)
    • C12N9/1044—Protein-glutamine gamma-glutamyltransferase (2.3.2.13), i.e. transglutaminase or factor XIII
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00—Preparation of peptides or proteins
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/40—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against enzymes

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biophysics (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biomedical Technology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Enzymes And Modification Thereof (AREA)

Abstract

A process for the purification of factor XIII or XIII A by immuno-affinity chromatography, monoclonal antibodies against F XIIIA, preparation and use thereof are described.
AU21246/92A 1991-08-22 1992-08-21 A process for the purification of factor XIII, monoclonal antibodies against factor XIIIA, the preparation and use thereof Ceased AU649868B2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE4127841A DE4127841A1 (en) 1991-08-22 1991-08-22 METHOD FOR PURIFYING FACTOR XIII, MONOCLONAL ANTIBODIES AGAINST FACTOR XIIIA, THEIR PRODUCTION AND USE
DE4127841 1991-08-22

Publications (2)

Publication Number Publication Date
AU2124692A true AU2124692A (en) 1993-02-25
AU649868B2 AU649868B2 (en) 1994-06-02

Family

ID=6438873

Family Applications (1)

Application Number Title Priority Date Filing Date
AU21246/92A Ceased AU649868B2 (en) 1991-08-22 1992-08-21 A process for the purification of factor XIII, monoclonal antibodies against factor XIIIA, the preparation and use thereof

Country Status (9)

Country Link
US (1) US5688919A (en)
EP (1) EP0529348B1 (en)
JP (1) JPH05268990A (en)
KR (1) KR100245542B1 (en)
AT (1) ATE226595T1 (en)
AU (1) AU649868B2 (en)
CA (1) CA2076557C (en)
DE (2) DE4127841A1 (en)
ES (1) ES2183803T3 (en)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100389197B1 (en) * 2000-03-17 2003-06-27 유지현 Air ventilation method by automatically escalating speed of fan according to indoor smoke density
US6660486B2 (en) * 2001-05-31 2003-12-09 Bio-Rad Laboratories, Inc. FXIII detection for verifying serum sample and sample size and for detecting dilution
US20070208163A1 (en) * 2003-07-10 2007-09-06 Novo Nordisk A/S Method for treatment of protein precipitates
WO2018111010A1 (en) * 2016-12-14 2018-06-21 (주) 팬젠 Anti-hemocoagulation factor viii antibody and use thereof
KR101989779B1 (en) * 2016-12-14 2019-06-17 (주) 팬젠 Anti-Blood Coagulation Factor VIII Antibody and Uses Thereof

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2121417A (en) * 1982-02-22 1983-12-21 Carlton Med Prod Antigens and antibodies useful in the detection of cancer
JPH01258700A (en) * 1988-04-05 1989-10-16 Green Cross Corp:The Purification of blood coagulation ix factor

Also Published As

Publication number Publication date
DE59209970D1 (en) 2002-11-28
EP0529348A1 (en) 1993-03-03
DE4127841A1 (en) 1993-02-25
EP0529348B1 (en) 2002-10-23
CA2076557C (en) 2007-05-01
AU649868B2 (en) 1994-06-02
JPH05268990A (en) 1993-10-19
ES2183803T3 (en) 2003-04-01
KR100245542B1 (en) 2000-02-15
KR930004476A (en) 1993-03-22
ATE226595T1 (en) 2002-11-15
CA2076557A1 (en) 1993-02-23
US5688919A (en) 1997-11-18

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Legal Events

Date Code Title Description
HB Alteration of name in register

Owner name: AVENTIS BEHRING GMBH

Free format text: FORMER NAME WAS: CENTEON PHARMA GMBH