DK0529279T3 - Fremgangsmåde til fremstilling af 5-(2,4-difluorphenyl)salicylsyre i ren form II - Google Patents

Fremgangsmåde til fremstilling af 5-(2,4-difluorphenyl)salicylsyre i ren form II

Info

Publication number
DK0529279T3
DK0529279T3 DK92112205.7T DK92112205T DK0529279T3 DK 0529279 T3 DK0529279 T3 DK 0529279T3 DK 92112205 T DK92112205 T DK 92112205T DK 0529279 T3 DK0529279 T3 DK 0529279T3
Authority
DK
Denmark
Prior art keywords
salicylic acid
difluorophenyl
preparation
pure form
diflurophenyl
Prior art date
Application number
DK92112205.7T
Other languages
English (en)
Inventor
Maurizio Paiocchi
Claudio Giordano
Original Assignee
Zambon Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Zambon Spa filed Critical Zambon Spa
Application granted granted Critical
Publication of DK0529279T3 publication Critical patent/DK0529279T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/42—Separation; Purification; Stabilisation; Use of additives
    • C07C51/43—Separation; Purification; Stabilisation; Use of additives by change of the physical state, e.g. crystallisation

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DK92112205.7T 1991-08-01 1992-08-01 Fremgangsmåde til fremstilling af 5-(2,4-difluorphenyl)salicylsyre i ren form II DK0529279T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ITMI912152A IT1250736B (it) 1991-08-01 1991-08-01 Processo per la preparazione dell'acido 5-(2',4'-difluorofenil) salicilico in forma ii pura

Publications (1)

Publication Number Publication Date
DK0529279T3 true DK0529279T3 (da) 1996-07-29

Family

ID=11360489

Family Applications (1)

Application Number Title Priority Date Filing Date
DK92112205.7T DK0529279T3 (da) 1991-08-01 1992-08-01 Fremgangsmåde til fremstilling af 5-(2,4-difluorphenyl)salicylsyre i ren form II

Country Status (9)

Country Link
US (1) US5183935A (da)
EP (1) EP0529279B1 (da)
JP (1) JPH07179395A (da)
AT (1) ATE139763T1 (da)
DE (1) DE69211788T2 (da)
DK (1) DK0529279T3 (da)
ES (1) ES2089305T3 (da)
GR (1) GR3020799T3 (da)
IT (1) IT1250736B (da)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL100353A (en) * 1991-01-08 1997-06-10 Zambon Spa Preparation of 5-(2, 4-difluorophenyl)-salicylic acid and novel 2,4-difluorophenyl-boronic acid derivatives being intermediates therefor

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1175212A (en) * 1967-03-09 1969-12-23 Merck & Co Inc Halo-Substituted 5-Phenylbenzoic Acids and their Derivatives
US4131618A (en) * 1977-12-29 1978-12-26 Merck & Co., Inc. Preparation of salicylic acid and derivatives
US4225730A (en) * 1978-05-11 1980-09-30 Merck & Co., Inc. Process for preparing 4-(2,4-difluorophenyl)-salicyclic acid
US4237315A (en) * 1979-11-02 1980-12-02 Merck & Co., Inc. Preparation of 5(halophenyl)salicylic acid compounds
IT1190926B (it) * 1982-07-22 1988-02-24 Zambon Spa Procedimento per preparare l'acido 2',4'-difluoro-4-idrossi-(1,1'-difenil)-3-carbossilico
IT1196485B (it) * 1986-07-14 1988-11-16 Zambon Spa Derivati dell'acido tiazolidin-4-carbossilico ad attivita' farmaceutica
US4847442A (en) * 1988-07-18 1989-07-11 Allied-Signal Inc. Process for the preparation of difluorobenzenes
US4996047A (en) * 1988-11-02 1991-02-26 Richardson-Vicks, Inc. Sustained release drug-resin complexes
JPH0768234B2 (ja) * 1989-12-14 1995-07-26 久光製薬株式会社 コウジ酸エステル誘導体

Also Published As

Publication number Publication date
IT1250736B (it) 1995-04-21
JPH07179395A (ja) 1995-07-18
DE69211788T2 (de) 1996-10-31
EP0529279A1 (en) 1993-03-03
EP0529279B1 (en) 1996-06-26
ES2089305T3 (es) 1996-10-01
GR3020799T3 (en) 1996-11-30
ITMI912152A1 (it) 1993-02-02
ATE139763T1 (de) 1996-07-15
US5183935A (en) 1993-02-02
ITMI912152A0 (it) 1991-08-01
DE69211788D1 (de) 1996-08-01

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