DK0519469T3 - Klonet glutaminsyre-decarboxylase - Google Patents

Klonet glutaminsyre-decarboxylase

Info

Publication number
DK0519469T3
DK0519469T3 DK92110308T DK92110308T DK0519469T3 DK 0519469 T3 DK0519469 T3 DK 0519469T3 DK 92110308 T DK92110308 T DK 92110308T DK 92110308 T DK92110308 T DK 92110308T DK 0519469 T3 DK0519469 T3 DK 0519469T3
Authority
DK
Denmark
Prior art keywords
glutamic acid
acid decarboxylase
gad65
cloned
cloned glutamic
Prior art date
Application number
DK92110308T
Other languages
Danish (da)
English (en)
Inventor
Allan J Tobin
Mark G Erlander
Daniel L Kaufman
Michael J Clare-Salzler
Original Assignee
Univ California
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ California filed Critical Univ California
Application granted granted Critical
Publication of DK0519469T3 publication Critical patent/DK0519469T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/52—Genes encoding for enzymes or proenzymes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y401/00—Carbon-carbon lyases (4.1)
    • C12Y401/01—Carboxy-lyases (4.1.1)
    • C12Y401/01015—Glutamate decarboxylase (4.1.1.15)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/88—Lyases (4.)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/04—Endocrine or metabolic disorders
    • G01N2800/042—Disorders of carbohydrate metabolism, e.g. diabetes, glucose metabolism

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Biomedical Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biophysics (AREA)
  • Transplantation (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Physics & Mathematics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Plant Pathology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Enzymes And Modification Thereof (AREA)
DK92110308T 1991-06-18 1992-06-17 Klonet glutaminsyre-decarboxylase DK0519469T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US71690991A 1991-06-18 1991-06-18

Publications (1)

Publication Number Publication Date
DK0519469T3 true DK0519469T3 (da) 2001-12-10

Family

ID=24879950

Family Applications (1)

Application Number Title Priority Date Filing Date
DK92110308T DK0519469T3 (da) 1991-06-18 1992-06-17 Klonet glutaminsyre-decarboxylase

Country Status (9)

Country Link
EP (2) EP0519469B1 (ko)
JP (1) JP4072922B2 (ko)
KR (1) KR100262247B1 (ko)
AT (2) ATE207537T1 (ko)
AU (1) AU661684B2 (ko)
CA (1) CA2070004C (ko)
DE (2) DE69233685T2 (ko)
DK (1) DK0519469T3 (ko)
ES (2) ES2281317T3 (ko)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5674978A (en) * 1990-09-21 1997-10-07 The Regents Of The University Of California Peptides derived from glutamic acid decarboxylase
DK88093D0 (da) * 1993-07-28 1993-07-28 Novo Nordisk As Stabilt praeparat
CN1112933A (zh) * 1994-01-20 1995-12-06 伯伦格·曼海姆有限公司 抗原特异性活化t淋巴细胞，其检测和用途
DE19525784A1 (de) * 1995-07-14 1997-01-16 Boehringer Mannheim Gmbh Autoreaktive Peptide aus der humanen Glutamin-Decarboxylase (GAD)
JP2000500120A (ja) * 1995-09-21 2000-01-11 ユニバーシティ・オブ・ユタ・リサーチ・ファウンデーション ポリ（エチレングリコール）と抗グルタミン酸デカルボキシラーゼ抗体の結合体の膵島細胞指向ターゲット化
CA2405265C (en) * 2000-04-17 2008-04-15 Loma Linda University Method of preventing or treating diabetes
GB0105360D0 (en) * 2001-03-03 2001-04-18 Glaxo Group Ltd Chimaeric immunogens
US20030054414A1 (en) * 2001-09-17 2003-03-20 George Jackowski Diagnosis and treatment of early pre-type-1 diabetes utilizing glial fibrillary acidic protein

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5205274A (en) * 1989-09-22 1993-04-27 Patentsmith Ii, Inc. Turntable convection oven
DE69122761T2 (de) * 1990-08-17 1997-03-13 Univ Florida Verfahren und komposition zum frühnachweiss und behandlung insulinabhängiger diabetes
DE69133393T2 (de) * 1990-09-07 2005-06-16 The Regents Of The University Of California, Oakland Verfahren zur diagnose und behandlung von diabetes
DE69233507T2 (de) * 1991-02-22 2009-09-10 The Walter And Eliza Hall Institute Of Medical Research, Parkville Hbgad und higad polypeptide und nukleinsäuren und deren verwendung zur diagnose und behandlung von gad autoantigen assoziierten krankheiten

Also Published As

Publication number Publication date
DE69233685D1 (de) 2007-04-12
DE69233685T2 (de) 2007-12-06
CA2070004A1 (en) 1992-12-19
AU1516392A (en) 1992-12-24
JPH0770182A (ja) 1995-03-14
DE69232147T2 (de) 2002-06-20
KR100262247B1 (ko) 2000-07-15
DE69232147D1 (de) 2001-11-29
JP4072922B2 (ja) 2008-04-09
ES2281317T3 (es) 2007-10-01
ATE207537T1 (de) 2001-11-15
ATE355364T1 (de) 2006-03-15
EP0519469A1 (en) 1992-12-23
EP1026238A3 (en) 2000-09-27
KR930000684A (ko) 1993-01-15
CA2070004C (en) 2007-08-21
EP0519469B1 (en) 2001-10-24
EP1026238A2 (en) 2000-08-09
EP1026238B1 (en) 2007-02-28
AU661684B2 (en) 1995-08-03
ES2165350T3 (es) 2002-03-16

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