DK0512066T3 - CO2-uafhængigt vækstmedium til opretholdelse og opformering af celler - Google Patents
CO2-uafhængigt vækstmedium til opretholdelse og opformering af cellerInfo
- Publication number
- DK0512066T3 DK0512066T3 DK91904443.8T DK91904443T DK0512066T3 DK 0512066 T3 DK0512066 T3 DK 0512066T3 DK 91904443 T DK91904443 T DK 91904443T DK 0512066 T3 DK0512066 T3 DK 0512066T3
- Authority
- DK
- Denmark
- Prior art keywords
- maintaining
- growth medium
- medium
- independent growth
- cells
- Prior art date
Links
- 239000001963 growth medium Substances 0.000 title abstract 2
- 230000001902 propagating effect Effects 0.000 title 1
- YBJHBAHKTGYVGT-ZKWXMUAHSA-N (+)-Biotin Chemical compound N1C(=O)N[C@@H]2[C@H](CCCCC(=O)O)SC[C@@H]21 YBJHBAHKTGYVGT-ZKWXMUAHSA-N 0.000 abstract 2
- DHCLVCXQIBBOPH-UHFFFAOYSA-N Glycerol 2-phosphate Chemical compound OCC(CO)OP(O)(O)=O DHCLVCXQIBBOPH-UHFFFAOYSA-N 0.000 abstract 2
- HNDVDQJCIGZPNO-YFKPBYRVSA-N L-histidine Chemical compound OC(=O)[C@@H](N)CC1=CN=CN1 HNDVDQJCIGZPNO-YFKPBYRVSA-N 0.000 abstract 2
- KDXKERNSBIXSRK-YFKPBYRVSA-N L-lysine Chemical compound NCCCC[C@H](N)C(O)=O KDXKERNSBIXSRK-YFKPBYRVSA-N 0.000 abstract 2
- OUYCCCASQSFEME-QMMMGPOBSA-N L-tyrosine Chemical compound OC(=O)[C@@H](N)CC1=CC=C(O)C=C1 OUYCCCASQSFEME-QMMMGPOBSA-N 0.000 abstract 2
- UIIMBOGNXHQVGW-UHFFFAOYSA-M Sodium bicarbonate Chemical compound [Na+].OC([O-])=O UIIMBOGNXHQVGW-UHFFFAOYSA-M 0.000 abstract 2
- 239000002609 medium Substances 0.000 abstract 2
- PWKSKIMOESPYIA-UHFFFAOYSA-N 2-acetamido-3-sulfanylpropanoic acid Chemical compound CC(=O)NC(CS)C(O)=O PWKSKIMOESPYIA-UHFFFAOYSA-N 0.000 abstract 1
- DCXYFEDJOCDNAF-UHFFFAOYSA-N Asparagine Natural products OC(=O)C(N)CC(N)=O DCXYFEDJOCDNAF-UHFFFAOYSA-N 0.000 abstract 1
- 235000019766 L-Lysine Nutrition 0.000 abstract 1
- ODKSFYDXXFIFQN-BYPYZUCNSA-N L-arginine Chemical compound OC(=O)[C@@H](N)CCCN=C(N)N ODKSFYDXXFIFQN-BYPYZUCNSA-N 0.000 abstract 1
- 229930064664 L-arginine Natural products 0.000 abstract 1
- 235000014852 L-arginine Nutrition 0.000 abstract 1
- DCXYFEDJOCDNAF-REOHCLBHSA-N L-asparagine Chemical compound OC(=O)[C@@H](N)CC(N)=O DCXYFEDJOCDNAF-REOHCLBHSA-N 0.000 abstract 1
- 239000004472 Lysine Substances 0.000 abstract 1
- LCTONWCANYUPML-UHFFFAOYSA-M Pyruvate Chemical compound CC(=O)C([O-])=O LCTONWCANYUPML-UHFFFAOYSA-M 0.000 abstract 1
- 239000012080 ambient air Substances 0.000 abstract 1
- 230000000259 anti-tumor effect Effects 0.000 abstract 1
- 229960001230 asparagine Drugs 0.000 abstract 1
- 235000009582 asparagine Nutrition 0.000 abstract 1
- 229960002685 biotin Drugs 0.000 abstract 1
- 235000020958 biotin Nutrition 0.000 abstract 1
- 239000011616 biotin Substances 0.000 abstract 1
- 210000004027 cell Anatomy 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 235000014113 dietary fatty acids Nutrition 0.000 abstract 1
- 229930195729 fatty acid Natural products 0.000 abstract 1
- 239000000194 fatty acid Substances 0.000 abstract 1
- 150000004665 fatty acids Chemical class 0.000 abstract 1
- 239000012458 free base Substances 0.000 abstract 1
- 229960002885 histidine Drugs 0.000 abstract 1
- 238000000338 in vitro Methods 0.000 abstract 1
- 229960003646 lysine Drugs 0.000 abstract 1
- 238000012423 maintenance Methods 0.000 abstract 1
- 229910000030 sodium bicarbonate Inorganic materials 0.000 abstract 1
- 235000017557 sodium bicarbonate Nutrition 0.000 abstract 1
- 210000004881 tumor cell Anatomy 0.000 abstract 1
- 229960004441 tyrosine Drugs 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/0018—Culture media for cell or tissue culture
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2500/00—Specific components of cell culture medium
- C12N2500/05—Inorganic components
- C12N2500/10—Metals; Metal chelators
- C12N2500/12—Light metals, i.e. alkali, alkaline earth, Be, Al, Mg
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2500/00—Specific components of cell culture medium
- C12N2500/05—Inorganic components
- C12N2500/10—Metals; Metal chelators
- C12N2500/20—Transition metals
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2500/00—Specific components of cell culture medium
- C12N2500/30—Organic components
- C12N2500/32—Amino acids
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2500/00—Specific components of cell culture medium
- C12N2500/30—Organic components
- C12N2500/38—Vitamins
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2500/00—Specific components of cell culture medium
- C12N2500/30—Organic components
- C12N2500/40—Nucleotides, nucleosides or bases
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2500/00—Specific components of cell culture medium
- C12N2500/30—Organic components
- C12N2500/42—Organic phosphate, e.g. beta glycerophosphate
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Biotechnology (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Genetics & Genomics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Cell Biology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
- Carbon And Carbon Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US46793990A | 1990-01-22 | 1990-01-22 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK0512066T3 true DK0512066T3 (da) | 1996-12-02 |
Family
ID=23857771
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK91904443.8T DK0512066T3 (da) | 1990-01-22 | 1991-01-22 | CO2-uafhængigt vækstmedium til opretholdelse og opformering af celler |
Country Status (8)
| Country | Link |
|---|---|
| EP (1) | EP0512066B1 (da) |
| JP (1) | JPH0789954B2 (da) |
| AT (1) | ATE145235T1 (da) |
| AU (1) | AU653927B2 (da) |
| CA (1) | CA2074363C (da) |
| DE (1) | DE69123140T2 (da) |
| DK (1) | DK0512066T3 (da) |
| WO (1) | WO1991010726A1 (da) |
Families Citing this family (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6475725B1 (en) | 1997-06-20 | 2002-11-05 | Baxter Aktiengesellschaft | Recombinant cell clones having increased stability and methods of making and using the same |
| WO1998059035A2 (en) * | 1997-06-25 | 1998-12-30 | The Goverment Of The United States Of America, Represented By The Secretary, Dept. Of Health And Human Services, National Institutes Of Health | Serum-free cell growth medium |
| AT409379B (de) | 1999-06-02 | 2002-07-25 | Baxter Ag | Medium zur protein- und serumfreien kultivierung von zellen |
| JP2001131009A (ja) * | 1999-10-29 | 2001-05-15 | Ajinomoto Co Inc | イネ科植物の枯死防止及び速効的栄養補給剤。 |
| JP4502098B2 (ja) | 2000-11-27 | 2010-07-14 | 味の素株式会社 | 植物用分けつ促進剤および植物の分けつ促進方法 |
| DK1520008T3 (da) | 2002-07-09 | 2012-10-15 | Baxter Int | Medium frit for dyreprotein til dyrkning af celler |
| AU2004212250B2 (en) * | 2003-02-14 | 2009-05-07 | Mars Incorporated | Skin composition |
| US20060094104A1 (en) | 2004-10-29 | 2006-05-04 | Leopold Grillberger | Animal protein-free media for cultivation of cells |
| RU2486236C2 (ru) | 2006-01-04 | 2013-06-27 | Бакстер Интернэшнл Инк. | Способ экспрессии белка |
| RU2017138926A (ru) | 2009-08-11 | 2019-02-11 | Дженентек, Инк. | Получение белков в культуральных средах без глутамина |
| SG181805A1 (en) * | 2009-12-18 | 2012-07-30 | Boehringer Ingelheim Int | Method for optimizing a biopharmaceutical production process |
| CA2827590C (en) | 2011-02-18 | 2020-09-01 | Stemcyte, Inc. | Stem cells packaging and shipping |
| SG11201403722RA (en) * | 2011-12-31 | 2014-10-30 | Agency Science Tech & Res | A method or device for identifying inhibitor of epithelial mesenchymal transition |
| WO2013143822A1 (en) | 2012-03-26 | 2013-10-03 | Imax Discovery Gmbh | Adenosine as sweetness enhancer for certain sugars |
| US20140170748A1 (en) * | 2012-12-14 | 2014-06-19 | DePuy Synthes Products, LLC | Nutrient Enriched Media for hUTC Growth |
| AU2014229281B2 (en) * | 2013-03-15 | 2017-05-11 | Glaxosmithkline Intellectual Property (No.2) Limited | Use of tricarboxylic acid (TCA) intermediates to control ammonia generation in cell culture |
| BR112018014238A2 (pt) | 2016-01-14 | 2018-12-11 | Depuy Synthes Products Inc | composição e métodos para criopreservação de hutc |
| JP2018113907A (ja) * | 2017-01-18 | 2018-07-26 | 株式会社Ｒｅｇｅｎｅ Ｐｈａｒｍ | 動物細胞の培養方法 |
| JP2020184972A (ja) * | 2019-05-17 | 2020-11-19 | 株式会社Ｒｅｇｅｎｅ Ｐｈａｒｍ | 新規培地 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3883393A (en) * | 1972-05-18 | 1975-05-13 | Us Health Education & Welfare | Cell culture on semi-permeable tubular membranes |
| US4411990A (en) * | 1979-06-13 | 1983-10-25 | University Patents, Inc. | Primary bioassay of human tumor stem cells |
| JPS57194787A (en) * | 1981-05-28 | 1982-11-30 | Ajinomoto Co Inc | Culture medium for animal cell |
| JPS6318465A (ja) * | 1986-07-10 | 1988-01-26 | Fujitsu Ltd | 移動最小二乗関数回帰回路 |
-
1991
- 1991-01-22 AT AT91904443T patent/ATE145235T1/de not_active IP Right Cessation
- 1991-01-22 DK DK91904443.8T patent/DK0512066T3/da active
- 1991-01-22 EP EP91904443A patent/EP0512066B1/en not_active Expired - Lifetime
- 1991-01-22 AU AU73001/91A patent/AU653927B2/en not_active Ceased
- 1991-01-22 DE DE69123140T patent/DE69123140T2/de not_active Expired - Fee Related
- 1991-01-22 WO PCT/US1991/000451 patent/WO1991010726A1/en active IP Right Grant
- 1991-01-22 JP JP3504839A patent/JPH0789954B2/ja not_active Expired - Lifetime
- 1991-01-22 CA CA002074363A patent/CA2074363C/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| DE69123140D1 (de) | 1996-12-19 |
| JPH05502379A (ja) | 1993-04-28 |
| WO1991010726A1 (en) | 1991-07-25 |
| CA2074363C (en) | 2004-11-09 |
| EP0512066A1 (en) | 1992-11-11 |
| DE69123140T2 (de) | 1997-04-03 |
| EP0512066A4 (en) | 1993-04-28 |
| JPH0789954B2 (ja) | 1995-10-04 |
| ATE145235T1 (de) | 1996-11-15 |
| CA2074363A1 (en) | 1991-07-23 |
| AU7300191A (en) | 1991-08-05 |
| EP0512066B1 (en) | 1996-11-13 |
| AU653927B2 (en) | 1994-10-20 |
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