DK0511917T3 - Glycosylerede prodrugs, fremgangsmåde til fremstilling deraf og anvendelse deraf - Google Patents

Glycosylerede prodrugs, fremgangsmåde til fremstilling deraf og anvendelse deraf

Info

Publication number
DK0511917T3
DK0511917T3 DK92401218.0T DK92401218T DK0511917T3 DK 0511917 T3 DK0511917 T3 DK 0511917T3 DK 92401218 T DK92401218 T DK 92401218T DK 0511917 T3 DK0511917 T3 DK 0511917T3
Authority
DK
Denmark
Prior art keywords
processes
preparation
glycosylated prodrugs
prodrugs
glycosylated
Prior art date
Application number
DK92401218.0T
Other languages
Danish (da)
English (en)
Inventor
Jean-Claude Florent
Jean-Claude Jacquesy
Claude Monneret
Gilbert Gaudel
J Czech
Jean-Pierre Gesson
Martine Mondon
Brigitte Renoux
Michel Koch
Francois Tillequin
Hans Harald Sedlacek
Manfred Gerken
Cenek Kolar
Klaus Bosslet
Dieter Hoffman
Gerhard Seeman
Hans-Ulrich Schorlemmer
Gerhard Dickneite
Original Assignee
Hoechst Sa Lab
Behringwerke Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Sa Lab, Behringwerke Ag filed Critical Hoechst Sa Lab
Application granted granted Critical
Publication of DK0511917T3 publication Critical patent/DK0511917T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20—Carbocyclic rings
    • C07H15/203—Monocyclic carbocyclic rings other than cyclohexane rings; Bicyclic carbocyclic ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
    • C07F7/02—Silicon compounds
    • C07F7/08—Compounds having one or more C—Si linkages
    • C07F7/18—Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
    • C07F7/1804—Compounds having Si-O-C linkages
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20—Carbocyclic rings
    • C07H15/24—Condensed ring systems having three or more rings
    • C07H15/252—Naphthacene radicals, e.g. daunomycins, adriamycins
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/26—Acyclic or carbocyclic radicals, substituted by hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Steroid Compounds (AREA)
DK92401218.0T 1991-04-30 1992-04-29 Glycosylerede prodrugs, fremgangsmåde til fremstilling deraf og anvendelse deraf DK0511917T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9105326A FR2676058B1 (fr) 1991-04-30 1991-04-30 Prodrogues glycosylees, leur procede de preparation et leur utilisation dans le traitement des cancers.

Publications (1)

Publication Number Publication Date
DK0511917T3 true DK0511917T3 (da) 1997-04-01

Family

ID=9412404

Family Applications (1)

Application Number Title Priority Date Filing Date
DK92401218.0T DK0511917T3 (da) 1991-04-30 1992-04-29 Glycosylerede prodrugs, fremgangsmåde til fremstilling deraf og anvendelse deraf

Country Status (16)

Country Link
US (1) US5561119A (uk)
EP (1) EP0511917B1 (uk)
JP (1) JP3053646B2 (uk)
KR (1) KR100254113B1 (uk)
AT (1) ATE144523T1 (uk)
AU (1) AU673138B2 (uk)
CA (1) CA2109304C (uk)
DE (1) DE69214712T2 (uk)
DK (1) DK0511917T3 (uk)
ES (1) ES2096735T3 (uk)
FR (1) FR2676058B1 (uk)
GR (1) GR3022344T3 (uk)
HK (1) HK1008020A1 (uk)
IE (1) IE921369A1 (uk)
UA (1) UA56981C2 (uk)
WO (1) WO1992019639A1 (uk)

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Also Published As

Publication number Publication date
FR2676058A1 (fr) 1992-11-06
IE921369A1 (en) 1992-11-04
JP3053646B2 (ja) 2000-06-19
KR100254113B1 (ko) 2000-04-15
ES2096735T3 (es) 1997-03-16
GR3022344T3 (en) 1997-04-30
ATE144523T1 (de) 1996-11-15
UA56981C2 (uk) 2003-06-16
AU1778892A (en) 1992-12-21
DE69214712T2 (de) 1997-05-07
EP0511917B1 (fr) 1996-10-23
JPH06506687A (ja) 1994-07-28
FR2676058B1 (fr) 1994-02-25
HK1008020A1 (en) 1999-04-30
AU673138B2 (en) 1996-10-31
CA2109304C (en) 2002-01-15
WO1992019639A1 (fr) 1992-11-12
US5561119A (en) 1996-10-01
EP0511917A1 (fr) 1992-11-04
DE69214712D1 (de) 1996-11-28
CA2109304A1 (en) 1992-10-31

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