DK0490823T3 - - Google Patents

Info

Publication number
DK0490823T3
DK0490823T3 DK91810954.7T DK91810954T DK0490823T3 DK 0490823 T3 DK0490823 T3 DK 0490823T3 DK 91810954 T DK91810954 T DK 91810954T DK 0490823 T3 DK0490823 T3 DK 0490823T3
Authority
DK
Denmark
Prior art keywords
4alkoxy
acid addition
addition salts
esters
isoquinolines
Prior art date
Application number
DK91810954.7T
Other languages
Danish (da)
English (en)
Inventor
Reto Naef
Original Assignee
Sandoz Ltd
Sandoz Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sandoz Ltd, Sandoz Ag filed Critical Sandoz Ltd
Application granted granted Critical
Publication of DK0490823T3 publication Critical patent/DK0490823T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/02—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with only hydrogen atoms or radicals containing only carbon and hydrogen atoms, directly attached to carbon atoms of the nitrogen-containing ring; Alkylene-bis-isoquinolines
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/12—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring
    • C07D217/14—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring other than aralkyl radicals
    • C07D217/16—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring other than aralkyl radicals substituted by oxygen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/08—Bronchodilators

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Pulmonology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Hydrogenated Pyridines (AREA)
DK91810954.7T 1990-12-13 1991-12-09 DK0490823T3 (zh)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB909027055A GB9027055D0 (en) 1990-12-13 1990-12-13 Organic compounds

Publications (1)

Publication Number Publication Date
DK0490823T3 true DK0490823T3 (zh) 1997-02-17

Family

ID=10686945

Family Applications (1)

Application Number Title Priority Date Filing Date
DK91810954.7T DK0490823T3 (zh) 1990-12-13 1991-12-09

Country Status (25)

Country Link
US (1) US5177085A (zh)
EP (1) EP0490823B1 (zh)
JP (1) JPH0764820B2 (zh)
KR (1) KR920012040A (zh)
AT (1) ATE145201T1 (zh)
AU (1) AU643575B2 (zh)
CA (1) CA2057524A1 (zh)
CZ (1) CZ281669B6 (zh)
DE (1) DE69123124T2 (zh)
DK (1) DK0490823T3 (zh)
ES (1) ES2093694T3 (zh)
FI (1) FI915844A (zh)
GB (1) GB9027055D0 (zh)
GR (1) GR3022034T3 (zh)
HU (1) HUT61729A (zh)
IE (1) IE914325A1 (zh)
IL (1) IL100328A (zh)
MX (1) MX9102502A (zh)
MY (1) MY129941A (zh)
NZ (1) NZ240936A (zh)
PL (1) PL168329B1 (zh)
PT (1) PT99775B (zh)
RU (1) RU2060992C1 (zh)
TW (1) TW201736B (zh)
ZA (1) ZA919858B (zh)

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US5786354A (en) * 1994-06-21 1998-07-28 Celltech Therapeutics, Limited Tri-substituted phenyl derivatives and processes for their preparation
US6245774B1 (en) 1994-06-21 2001-06-12 Celltech Therapeutics Limited Tri-substituted phenyl or pyridine derivatives
GB9412571D0 (en) 1994-06-22 1994-08-10 Celltech Ltd Chemical compounds
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AU2593997A (en) * 1996-03-21 1997-10-10 Trustees Of Columbia University In The City Of New York, The Craf1 (traf-3) isoforms and uses thereof
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GB9608435D0 (en) * 1996-04-24 1996-06-26 Celltech Therapeutics Ltd Chemical compounds
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AU5330698A (en) 1996-12-23 1998-07-17 Celltech Therapeutics Limited Fused polycyclic 2-aminopyrimidine derivatives, their preparation and their use as protein tyrosine kinase inhibitors
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GB9713087D0 (en) * 1997-06-20 1997-08-27 Celltech Therapeutics Ltd Chemical compounds
JP2001510825A (ja) * 1997-07-25 2001-08-07 ビイク グルデン ロンベルク ヒエーミツシエ フアブリーク ゲゼルシヤフト ミツト ベシユレンクテル ハフツング 新規テトラゾール誘導体
WO1999016752A1 (en) * 1997-09-30 1999-04-08 Molecular Designs International, Inc. β3-ADRENORECEPTOR AGONISTS, AGONIST COMPOSITIONS AND METHODS OF USING
IT1296985B1 (it) 1997-12-19 1999-08-03 Zambon Spa Derivati benzazinici inibitori della fosfodiesterasi 4
IT1302677B1 (it) * 1998-10-15 2000-09-29 Zambon Spa Derivati benzazinici inibitori della fosfodiesterasi 4
GB9914258D0 (en) 1999-06-18 1999-08-18 Celltech Therapeutics Ltd Chemical compounds
KR100701904B1 (ko) 1999-08-21 2007-04-02 알타나 파마 아게 Ｐｄｅ 억제제 및 베타 2 아드레날린수용체 작동제의상승적 조합
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WO2001070746A1 (fr) * 2000-03-23 2001-09-27 Takeda Chemical Industries, Ltd. Derives de furoisoquinoleine, leur procede de production et leur utilisation
WO2002040449A1 (en) * 2000-11-14 2002-05-23 Altana Pharma Ag Dihydroisoquinolines as novel phosphodiesterase inhibitors
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MXPA03010810A (es) * 2001-05-29 2004-03-22 Schering Ag Pirimidinas inhibidoras de cdk, su obtencion y su uso como medicamentos.
KR100836547B1 (ko) 2002-01-11 2008-06-10 상꾜 가부시키가이샤 아미노 알코올 유도체 또는 포스폰산 유도체 및 이들을함유하는 의약 조성물
US7745180B2 (en) * 2002-04-24 2010-06-29 Hitachi Chemical Co., Ltd. Device and method for high-throughput quantification of mRNA from whole blood
AU2003253408A1 (en) * 2002-08-17 2004-03-11 Nycomed Gmbh Novel phenanthridines
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JP5546451B2 (ja) 2007-06-04 2014-07-09 シナジー ファーマシューティカルズ インコーポレイテッド 胃腸の障害、炎症、癌および他の障害の処置に有用なグアニル酸シクラーゼのアゴニスト
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Also Published As

Publication number Publication date
DE69123124D1 (de) 1996-12-19
DE69123124T2 (de) 1997-05-15
FI915844A (fi) 1992-06-14
EP0490823A1 (en) 1992-06-17
PT99775B (pt) 1999-05-31
IL100328A0 (en) 1992-09-06
RU2060992C1 (ru) 1996-05-27
EP0490823B1 (en) 1996-11-13
IL100328A (en) 1995-12-08
CA2057524A1 (en) 1992-06-14
JPH0764820B2 (ja) 1995-07-12
GB9027055D0 (en) 1991-02-06
MX9102502A (es) 1992-06-01
GR3022034T3 (en) 1997-03-31
FI915844A0 (fi) 1991-12-11
NZ240936A (en) 1993-09-27
HUT61729A (en) 1993-03-01
MY129941A (en) 2007-05-31
CZ281669B6 (cs) 1996-12-11
AU643575B2 (en) 1993-11-18
CS375791A3 (en) 1992-06-17
HU913760D0 (en) 1992-02-28
ES2093694T3 (es) 1997-01-01
KR920012040A (ko) 1992-07-25
TW201736B (zh) 1993-03-11
ZA919858B (en) 1993-06-14
PL292738A1 (en) 1992-12-14
AU8898591A (en) 1992-06-18
PL168329B1 (pl) 1996-02-29
US5177085A (en) 1993-01-05
PT99775A (pt) 1992-11-30
ATE145201T1 (de) 1996-11-15
JPH04275276A (ja) 1992-09-30
IE914325A1 (en) 1992-06-17

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