DK0472526T3 - 5-aminocarbonyl-5H-dibenzo(a,d)cyclohepten-5,10-iminer til behandling af epilepsi og cocainmisbrug - Google Patents
5-aminocarbonyl-5H-dibenzo(a,d)cyclohepten-5,10-iminer til behandling af epilepsi og cocainmisbrugInfo
- Publication number
- DK0472526T3 DK0472526T3 DK90905307.6T DK90905307T DK0472526T3 DK 0472526 T3 DK0472526 T3 DK 0472526T3 DK 90905307 T DK90905307 T DK 90905307T DK 0472526 T3 DK0472526 T3 DK 0472526T3
- Authority
- DK
- Denmark
- Prior art keywords
- treatment
- epilepsy
- cyclohepten
- dibenzo
- imines
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D451/00—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Life Sciences & Earth Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Pain & Pain Management (AREA)
- Addiction (AREA)
- Psychiatry (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US34918789A | 1989-05-09 | 1989-05-09 |
Publications (1)
Publication Number | Publication Date |
---|---|
DK0472526T3 true DK0472526T3 (da) | 1996-07-29 |
Family
ID=23371261
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK90905307.6T DK0472526T3 (da) | 1989-05-09 | 1990-03-23 | 5-aminocarbonyl-5H-dibenzo(a,d)cyclohepten-5,10-iminer til behandling af epilepsi og cocainmisbrug |
Country Status (9)
Country | Link |
---|---|
EP (1) | EP0472526B1 (da) |
JP (2) | JPH07119224B2 (da) |
AT (1) | ATE137752T1 (da) |
AU (1) | AU637364B2 (da) |
CA (1) | CA2053247C (da) |
DE (1) | DE69026936T2 (da) |
DK (1) | DK0472526T3 (da) |
ES (1) | ES2091820T3 (da) |
WO (1) | WO1990013297A1 (da) |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU4540193A (en) * | 1992-06-17 | 1994-01-04 | United States Of America, Represented By The Secretary, Department Of Health And Human Services, The | Method of treating and protecting against central nervous system ischemia, hypoxia, degeneration, and trauma with a 5-aminocarbonyl-sh-dibenzo{a,d}cyclohepten-5,10-imine |
US5686614A (en) * | 1995-04-11 | 1997-11-11 | Neurogen Corporation | Preparation of chiral 5-aminocarbonyl-5H-dibenzo a,d!cyclohepten-5,10-imines by optical resolution |
US5739337A (en) * | 1996-03-08 | 1998-04-14 | Neurogen Corporation | Process for preparing dibenzo-1-carboxamido-1,4-azabicyclo 3.2.1!octanes |
AU6765598A (en) * | 1997-03-20 | 1998-10-12 | Neurogen Corporation | Process for preparing dibenzo-1-carboxamido-1,4-azabicyclo(3.2.1.) octanes |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
BE794904A (fr) * | 1972-02-04 | 1973-08-02 | Roussel Uclaf | Nouveaux derives du dibenzocycloheptene et leur preparation |
US4399141A (en) * | 1977-09-19 | 1983-08-16 | Merck & Co., Inc. | 5-Alkyl or hydroxyalkyl substituted-10,11-dihydro-5H-dibenzo[a,d]cyclohepten-5,10-imines and anticonvulsant use thereof |
NZ221626A (en) * | 1986-09-08 | 1989-11-28 | Merck & Co Inc | Dibenzo(a,d cycloheptene derivatives and pharmaceutical compositions |
NZ225634A (en) * | 1987-08-10 | 1991-03-26 | Merck & Co Inc | 10,11-dihydro-5h-dibenzo(a,d)cyclohepten-5,10-imine derivatives and pharmaceutical compositions |
-
1990
- 1990-03-23 AT AT90905307T patent/ATE137752T1/de not_active IP Right Cessation
- 1990-03-23 EP EP90905307A patent/EP0472526B1/en not_active Expired - Lifetime
- 1990-03-23 DK DK90905307.6T patent/DK0472526T3/da active
- 1990-03-23 AU AU53396/90A patent/AU637364B2/en not_active Ceased
- 1990-03-23 ES ES90905307T patent/ES2091820T3/es not_active Expired - Lifetime
- 1990-03-23 CA CA002053247A patent/CA2053247C/en not_active Expired - Fee Related
- 1990-03-23 WO PCT/US1990/001502 patent/WO1990013297A1/en active IP Right Grant
- 1990-03-23 JP JP2505273A patent/JPH07119224B2/ja not_active Expired - Lifetime
- 1990-03-23 DE DE69026936T patent/DE69026936T2/de not_active Expired - Fee Related
-
1995
- 1995-06-13 JP JP7146525A patent/JP2798628B2/ja not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
JP2798628B2 (ja) | 1998-09-17 |
CA2053247A1 (en) | 1990-11-10 |
CA2053247C (en) | 1996-01-02 |
AU637364B2 (en) | 1993-05-27 |
DE69026936T2 (de) | 1997-01-16 |
EP0472526A1 (en) | 1992-03-04 |
JPH04503216A (ja) | 1992-06-11 |
WO1990013297A1 (en) | 1990-11-15 |
ATE137752T1 (de) | 1996-05-15 |
EP0472526A4 (en) | 1992-05-20 |
JPH08157474A (ja) | 1996-06-18 |
DE69026936D1 (de) | 1996-06-13 |
JPH07119224B2 (ja) | 1995-12-20 |
AU5339690A (en) | 1990-11-29 |
ES2091820T3 (es) | 1996-11-16 |
EP0472526B1 (en) | 1996-05-08 |
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