DK0459381T3 - Fremgangsmåde til fremstilling af 10-(2-propynyl)-østr-4-en-3,17-dion - Google Patents

Fremgangsmåde til fremstilling af 10-(2-propynyl)-østr-4-en-3,17-dion

Info

Publication number
DK0459381T3
DK0459381T3 DK91108664.3T DK91108664T DK0459381T3 DK 0459381 T3 DK0459381 T3 DK 0459381T3 DK 91108664 T DK91108664 T DK 91108664T DK 0459381 T3 DK0459381 T3 DK 0459381T3
Authority
DK
Denmark
Prior art keywords
dione
ene
propynyl
preparation
ester
Prior art date
Application number
DK91108664.3T
Other languages
English (en)
Inventor
Jeffrey P Whitten
Harvey D Benson
Cynthia L Rand
Original Assignee
Merrell Pharma Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merrell Pharma Inc filed Critical Merrell Pharma Inc
Application granted granted Critical
Publication of DK0459381T3 publication Critical patent/DK0459381T3/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J1/00Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
    • C07J1/0051Estrane derivatives
    • C07J1/0059Estrane derivatives substituted in position 17 by a keto group
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J21/00Normal steroids containing carbon, hydrogen, halogen or oxygen having an oxygen-containing hetero ring spiro-condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • C07J21/005Ketals
    • C07J21/008Ketals at position 17
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J51/00Normal steroids with unmodified cyclopenta(a)hydrophenanthrene skeleton not provided for in groups C07J1/00 - C07J43/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J71/00Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
    • C07J71/0005Oxygen-containing hetero ring
    • C07J71/001Oxiranes

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Steroid Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DK91108664.3T 1990-05-30 1991-05-28 Fremgangsmåde til fremstilling af 10-(2-propynyl)-østr-4-en-3,17-dion DK0459381T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US53067490A 1990-05-30 1990-05-30

Publications (1)

Publication Number Publication Date
DK0459381T3 true DK0459381T3 (da) 1997-04-07

Family

ID=24114524

Family Applications (1)

Application Number Title Priority Date Filing Date
DK91108664.3T DK0459381T3 (da) 1990-05-30 1991-05-28 Fremgangsmåde til fremstilling af 10-(2-propynyl)-østr-4-en-3,17-dion

Country Status (13)

Country Link
EP (1) EP0459381B1 (da)
JP (1) JP2989935B2 (da)
KR (1) KR0171410B1 (da)
AT (1) ATE150465T1 (da)
AU (1) AU649251B2 (da)
DE (1) DE69125207T2 (da)
DK (1) DK0459381T3 (da)
ES (1) ES2101702T3 (da)
GR (1) GR3023380T3 (da)
HU (1) HU212575B (da)
IE (1) IE911834A1 (da)
IL (1) IL98384A (da)
ZA (1) ZA913963B (da)

Also Published As

Publication number Publication date
JP2989935B2 (ja) 1999-12-13
ZA913963B (en) 1992-04-29
IE911834A1 (en) 1991-12-04
HU212575B (en) 1996-08-29
KR0171410B1 (ko) 1999-02-01
EP0459381A3 (en) 1992-06-10
ATE150465T1 (de) 1997-04-15
JPH04235997A (ja) 1992-08-25
HUT57791A (en) 1991-12-30
GR3023380T3 (en) 1997-08-29
AU649251B2 (en) 1994-05-19
DE69125207D1 (de) 1997-04-24
IL98384A (en) 1995-03-30
KR910020028A (ko) 1991-12-19
ES2101702T3 (es) 1997-07-16
AU7729091A (en) 1991-12-05
EP0459381B1 (en) 1997-03-19
EP0459381A2 (en) 1991-12-04
DE69125207T2 (de) 1997-06-26

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