DK0386668T3 - Lyofiliseret dihydrochlorid af 7-[alfa-(2-aminothiazol-4-yl)-alfa-(Z)-methoxyiminoacetamido]-3-[(1-methyl-1-pyrrolidinium)m - Google Patents

Lyofiliseret dihydrochlorid af 7-[alfa-(2-aminothiazol-4-yl)-alfa-(Z)-methoxyiminoacetamido]-3-[(1-methyl-1-pyrrolidinium)m

Info

Publication number
DK0386668T3
DK0386668T3 DK90104182T DK90104182T DK0386668T3 DK 0386668 T3 DK0386668 T3 DK 0386668T3 DK 90104182 T DK90104182 T DK 90104182T DK 90104182 T DK90104182 T DK 90104182T DK 0386668 T3 DK0386668 T3 DK 0386668T3
Authority
DK
Denmark
Prior art keywords
alpha
methyl
lyophilized
methoxyiminoacetamido
aminothiazol
Prior art date
Application number
DK90104182T
Other languages
English (en)
Inventor
Murray A Kaplan
Munir N Nassar
Original Assignee
Bristol Myers Squibb Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Squibb Co filed Critical Bristol Myers Squibb Co
Application granted granted Critical
Publication of DK0386668T3 publication Critical patent/DK0386668T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
    • C07D501/38—Methylene radicals, substituted by nitrogen atoms; Lactams thereof with the 2-carboxyl group; Methylene radicals substituted by nitrogen-containing hetero rings attached by the ring nitrogen atom; Quaternary compounds thereof
    • C07D501/46—Methylene radicals, substituted by nitrogen atoms; Lactams thereof with the 2-carboxyl group; Methylene radicals substituted by nitrogen-containing hetero rings attached by the ring nitrogen atom; Quaternary compounds thereof with the 7-amino radical acylated by carboxylic acids containing hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
DK90104182T 1989-03-06 1990-03-05 Lyofiliseret dihydrochlorid af 7-[alfa-(2-aminothiazol-4-yl)-alfa-(Z)-methoxyiminoacetamido]-3-[(1-methyl-1-pyrrolidinium)m DK0386668T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US31898589A 1989-03-06 1989-03-06

Publications (1)

Publication Number Publication Date
DK0386668T3 true DK0386668T3 (da) 1999-07-19

Family

ID=23240400

Family Applications (1)

Application Number Title Priority Date Filing Date
DK90104182T DK0386668T3 (da) 1989-03-06 1990-03-05 Lyofiliseret dihydrochlorid af 7-[alfa-(2-aminothiazol-4-yl)-alfa-(Z)-methoxyiminoacetamido]-3-[(1-methyl-1-pyrrolidinium)m

Country Status (8)

Country Link
US (1) US5095011A (da)
EP (1) EP0386668B1 (da)
JP (1) JP2958567B2 (da)
AT (1) ATE172977T1 (da)
CA (1) CA2011116C (da)
DE (1) DE69032733T2 (da)
DK (1) DK0386668T3 (da)
ES (1) ES2125218T3 (da)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2329244T3 (es) * 2003-03-27 2009-11-24 Basilea Pharmaceutica Ag Cefalosporina en forma cristalina.
WO2006109324A2 (en) * 2005-04-13 2006-10-19 Lupin Limited Processes for preparation of amorphous cefepime acid addition salts
US20080108664A1 (en) 2005-12-23 2008-05-08 Liu Belle B Solid-state form of AMG 706 and pharmaceutical compositions thereof
CN104119294B (zh) * 2006-03-29 2018-10-30 维斯塔实验室有限公司 3,7-二氨基-10h-吩噻嗪化合物的制备方法
EP2015755A4 (en) * 2006-04-28 2010-02-24 Wockhardt Ltd ENHANCED TREATMENT FOR TREATING BACTERIAL RESISTANT INFECTIONS
SI2673266T1 (sl) 2011-02-11 2016-11-30 Wista Laboratories Ltd. Fenotiazin diaminijeve soli in njihova uporaba
CN103304580B (zh) * 2013-06-09 2014-07-09 四川省惠达药业有限公司 一种盐酸头孢吡肟化合物、其制备方法及其药物组合物
CN114042048B (zh) * 2021-10-29 2023-02-28 海南海灵化学制药有限公司 一种注射用盐酸头孢吡肟的制备工艺

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1213882A (en) * 1982-03-04 1986-11-12 Jun Okumura Cephalosporins
US4406899A (en) * 1982-03-04 1983-09-27 Bristol-Myers Company Cephalosporins
FR2585705B1 (fr) * 1985-08-05 1989-01-13 Bristol Myers Co Sels de cephalosporine et compositions injectables
US4910301A (en) * 1985-08-05 1990-03-20 Bristol-Myers Company Cefepime cephalosporin salts
US4808617A (en) * 1985-12-18 1989-02-28 Bristol-Myers Company Lyophilized or precipitated cephalosporin zwitterion and salt combination

Also Published As

Publication number Publication date
US5095011A (en) 1992-03-10
EP0386668A3 (en) 1992-01-08
CA2011116C (en) 1999-11-16
EP0386668A2 (en) 1990-09-12
EP0386668B1 (en) 1998-11-04
JP2958567B2 (ja) 1999-10-06
DE69032733T2 (de) 1999-07-08
DE69032733D1 (de) 1998-12-10
ES2125218T3 (es) 1999-03-01
CA2011116A1 (en) 1990-09-06
ATE172977T1 (de) 1998-11-15
JPH02273684A (ja) 1990-11-08

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