DE933708C - Method and machine for processing ampoules or the like. - Google Patents

Description

The ampoule processing takes place today mainly in such a way that the ampoules from Hand cut off one by one, then cleaned and dried in large quantities, then individually filled and melted by a semi or fully automatic machine, then in Sterilized larger quantities, then checked for density and cleaned and finally again individually labeled in a printing machine, whereupon they again to Dry to be stacked and finally packed.

This method of operation has the major disadvantage that each ampoule because of the required multiple intermediate stacks must be handled several times and that despite high Labor and space requirements are relatively low and the reject rate is large.

The main reason for the high committee is the following. The scoring the ampoules are deficient, often at an angle or at different heights, so that after breaking off, which usually also get splinters into the inside of the ampoule, with ampoules of different lengths splintered break edge arise. Through the intermediate stacks and especially through the Cleaning according to the vacuum process and also when centering and inserting the filling needles result there are more splinters at the edges of the break. It cannot be expected that one Melting machine seals such different and splintered ampoules properly.

Cleaning the inside of the ampoule using the vacuum process does not provide a full guarantee for Freedom from splinters and fibers. Sometimes even externally adhering ones get through this process Impurities get into the interior of the ampoules and stick there, which is why often on any Cleaning is dispensed with. In any case, arises

further, often considerable, rejects to be sorted out requires a very time-consuming and therefore costly test.

The numerous intermediate stacks of the ampoules between the individual processing operations. Causes further loss through breakage or damage, plus the dirt and Damage to the fresh print occurs when the ampoules are stacked to dry

ίο touch each other.

In addition to these qualitative defects and the resulting and already general manual work Conditional inefficiency is another very palpable shortcoming that most are known to have Machining devices allow only very little adjustability, so only for limited Ampoule sizes can be used.

To. Establishing the causes of the current deficiencies, the invention has the task of to develop a method for processing ampoules, which is the manual labor and the largely eliminates disadvantageous intermediate stacks and also the others for the committee avoids or eliminates responsible disadvantages. Another purpose of the invention is in the creation of devices for carrying out the process, including ampoules of the most varied Allowing size and shapes to be processed and ultimately in the simplest possible manner Way also as a so-called multiple machine, which at each work station at the same time several to one Series of combined ampoules can be processed, trained, and processed.

Part of the solution to this problem is to first determine the main requirements for which the Must comply with the procedure. The ampoules must be closed individually and, if possible, in series Work through the individual jobs required for treatment, from which at least two require a completely different working position of the ampoule, namely breaking off the skewer with the skewer pointing downwards and filling it with the skewer pointing upwards. judged: spit, while at the other jobs no compelling reason for a particular The working position of the ampoule exists, with the exception of melting and pressing the ampoules, in which a horizontal or upright position of the ampoule would be advantageous. Further the ampoules must be at each work place and expediently during the promotion both be immovably mounted in the lateral as well as in the longitudinal direction and at individual workplaces (melting, Printing and possibly scoring) can be rotated around their longitudinal axis without centrifuging can. The storage must have the space required for labeling the ampoule as possible let freedom free.

The invention takes these aforementioned technical requirements into account in such a way that that the ampoules individually or in groups with constant storage of their skewer on one Sponsors are continuously funded from job to job and so by the sponsor at every work place, avoiding special adjustment measures required correct location.

The constant storage of the skewer can be achieved according to the invention in that the ampoules in contrast to the previous method on one they against lateral or longitudinal shifts securing, but their rotation about their longitudinal axis permitting substrate conveyed lying and a required change in position in each case only experienced at or shortly before the job causing this change of location, whereby processing depending on the requirements of the work process during the standstill or takes place during funding.

For this purpose, the ampoules according to the invention are advantageously in an obliquely upright _v position with their body just above the ground and with their skewer not far below the future melting point in a fork or notch and, with their bottom lying on a retaining wall, conveyed and to the workplaces that require a different position are transferred into this work position by moving the carrier or its support, whereby they are protected against falling out or shifting by a clamping device. Here, ampoules combined in groups can be conveyed to the individual workplaces in the same notches of the same carrier, which holds a certain number of ampoules, remaining with it, after which the carrier is conveyed empty to the exit point. However, the ampoules lying on a frame as a carrier can also be lifted out of the notches of the frame by an expediently also with notches or the like.

For moving the ampoule carriers or for conveying those lying on the racks The invention offers various possibilities for ampoules and their storage on other frame sections. You can for example take place on a circular path, with the transfer of the ampoule carrier or frame sections in the respectively required other working position during the Standstill at the relevant workplaces or beforehand, for example through a curved path, is carried out during the promotion.

The conveyance of the ampoules or their carriers according to the invention has proven to be particularly advantageous on one or more rectilinear paths and the transfer of the ampoules into the relevant Working position or the transition to another path through movable sections of a Guideway.

Through this promotion on straight tracks, the conveyor itself becomes like the Installation and drive of the individual work equipment and finally the adjustability significantly reduced for different ampoule sizes

simple. Above all, however, this method of working results in simultaneous processing several ampoules combined to form a group at each work site, structurally very simple Solutions for high-performance machines.

The new V ^er fa-h ^ren also allows particularly advantageous to carry out all necessary treatment processes of ampoules in detail and allows for different treatments even the

ίο optional application of different working methods to.

For example, the ampoules can be scored by placing them on their carrier lying ampoules by a friction wheel, endless friction belt or the like for the purpose of scratching their Skewer are set in rotation about its longitudinal axis and that the skewer at the same time by a Scoring device is resiliently touched.

This scribing can also be done during the promotion, with the lying on the carrier Ampoules rolling on a stationary elastic friction surface and at the same time with their rotating skewers are slidably guided on a resiliently mounted scoring device.

Deviating from this, especially in the case of ampoules with skewers of small diameter, which can be dispensed with an all-round incised line, can also be proceeded in this way, that the ampoules lying on their carrier are held by a clamping device and expediently brought into the position with the skewer pointing downwards or diagonally downwards whereupon the scoring is done by guiding the ampoules along a scoring device or

Long guide the Ritzeinriclitung is effected on the ampoules.

According to the invention, the incised skewers are broken off after the ampoules have been clamped on their support either while in their position with the skewer pointing downwards their standstill by a hammer or during their pivoting movement on a turning device by bumping the skewer against a fixed stop, so that the penetration splinters into the inside of the ampoule is prevented.

By resilient support of the ampoules close to the break point by means of a movable one Abutment for absorbing the crushing blow can have the possibility of splinters Knocking off can be further reduced.

As a special advantage, the new process offers the possibility for the first time to really Carry out proper internal cleaning by spraying each one with the spit opening downward-pointing ampoule with one introduced through a hollow needle from below Cleaning fluid can be done effectively. Since the previous method no way to Mechanical application of this working method offered, but its application by hand when putting it on of the ampoules via spray nozzles to damage and splintering of the spit cut edges and since the vacuum process often causes contamination instead of cleaning caused the ampoules, cleaning was mostly dispensed with and at a subsequent optical inspection, a separation of at least the ampoules in which Glass fragments or fibers were visible, made while soluble or because of them Smallness undetected impurities remained undetected and often irritation or complications caused after injection of these ampoule contents.

According to the invention, the inside of the ampoules is cleaned in such a way that in the on the carrier lying and held centered in the frame notches by a clamping device, with their skewers downward or obliquely downward pointing ampoules without further preparation Cleaning needles are introduced through which one or more cleaning fluids or the like. are injected, and that through the same or different hollow needles on the same or one later job air or hot air for the purpose of pressing out liquid residues and drying can be initiated.

Steam or hot air can also be introduced using the same procedure, whereby a Sterilization of the empty ampoules is effected.

At the filling point, the procedure is that the ampoules by a clamping device in the Carrier are held and by moving the carrier or its base in the upright filling position be swiveled, in which the filling needles without further preparation in the ampoule interior be introduced, the filling being carried out in a known manner and with back suction of the last drop, so that no wetting of the spit can occur.

In order to avoid liquid loss and machine contamination if the ampoule is missing, sensing devices can be provided, which the filling device only then in Allow activity to take place when there is an ampoule at the work site concerned. That can be done in the new method in a very simple manner that when erecting the ampoules at the filling point by placing the ampoule skewers against the movable buttons of the filling mechanism is brought into connection with its drive, or by the fact that a blocking element for at the filling point through the ampoules the filling needle is pushed into the release position and, after the filling needle has fully sunk, through its Guide rod of the filling mechanism is set in motion.

Because the ampoule skewers are melted shut, the normal incline of the ampoules in the Carrier notches is a particularly favorable working position, the ampoules remain according to the invention at the melting point in their normal inclined upright position, which they assume during conveyance, in the notches of the carrier and are only held by a rotating friction wheel, an endless belt

Od. The like. Set in rotation about its longitudinal axis, while at the same time jet flames spread their skewers and melt.

The inclined position - 5 according to the new process - is also conceivable for printing favorable preconditions for a wide variety of printing processes. The printing of the ampoules is carried out during a conveying step by placing the in the individual carrier notches ίο lying ampoules under a pressure plate or one previously printed in one or more colors Pressure transfer plate rolled off and provided with the lettering.

So that a constant pressure of the ampoules on the pressure medium is guaranteed, Differences in the ampoule diameter are compensated for and even non-round ampoule bodies unroll properly, it is advisable to keep the ampoules on springy while pressing stored forks or notches rest and from the fork to be placed after the skewer instead of on the to support the upper end of the ampoule body.

So that each ampoule only receives the imprint intended for it, the ampoules are during their conveying step for the printing process only over the area of the printing intended for them - brought into rolling contact with the pressure or pressure transfer plate. This can be achieved, for example, in that the ampoules during their conveying step for their printing to be moved on a circular path, which is both the length of the Funding step as well as the rolling position 'is adapted.

In cases where the pressure range is greater than the distance between two ampoules, printing takes place according to the invention in two groups, namely in such a way that initially every second. Ampoule lifted over the other ampoules and taking the carrier with it and the remaining ampoules is rolled under the pressure roller, whereupon the other ampoules in lifted and through in the same way over the group of ampoules printed first Rolling on the printing plate are printed.

Instead of pressing during conveyance, the procedure can also be such that the ampoules lying on a carrier and expediently in resilient forks are printed during the standstill by rolling over a pressure or pressure transfer roller or sliding over a pressure or pressure transfer plate. While the ampoules printed by hand or by machine had to be stacked to dry according to the previous method, whereby the still fresh print would be damaged by and on or with these further conveyed and freely accessible ampoules by heating devices _% such. B. by weak flames touching the Amr pulp body, is dried or burned in before the ampoules leave the system.

The ejection of the ampoules after they have been processed is also carried out in an orderly manner so that that the ampoules by lifting them out of their carrier over a distance if necessary between the ampoules reducing slide in collective transport containers or transport devices or be fed directly into the sales package.

The new process allows for the first time, not just every single one in the ampoule production required treatment in a manner that meets all requirements carry out, but also all necessary individual treatments in a closed, through no intermediate stacking or intermediate handling interrupted work process with very summarize simple technical means. So the above mentioned, the high Defects in the previous working method that cause melt scrap can be avoided by that the ampoules are scratched, opened, individually or in groups in a continuous operation, filled and closed.

Through this closed process, the penetration of glass splinters into the interior of the ampoule is prevented with certainty and thus the otherwise resulting scrap of ampoules containing splinters avoided.

By switching on the internal cleaning, drying and, if necessary, the sterilization of the Empty ampoules before they are filled in the related operation is fully guaranteed for splinter-free and fiber-free ampoules with the elimination of time-consuming subsequent testing given. In addition, soluble impurities, which are often the cause, are also avoided irritation after injections.

Furthermore, the new method allows the simplest means to exclude the risk of confusion Desired activation of the printing and the subsequent drying or burning in the lettering in the related operation.

This in turn leads to intermediate stacking, intermediate handling and damage the ampoules and their labeling avoided. The invention provides for ampoules to be sterilized the possibility of the filled ampoules following the connected Operation by means of the same conveyor device through a sterilization chamber or the like convey or mechanically to another, through a Sterilisier'kammer or a Sterilisierbad leading transport facility.

At the same time, a very reliable leak test of the ampoules is connected to this by the sterilization of the ampoules in the sterilization chamber with permanently or temporarily down directed fusible link is carried out,

because of the increased internal pressure when the temperature rises, even with the smallest leak The contents of the ampoule are squeezed out of the fusible link and leaky ampoules can thus be identified.

Since such a density test the previously used test methods, z. B. Immersion in color solutions, surpasses reliability and also the associated disadvantages of the ίο subsequent drying and polishing of each one Avoiding the ampoule, it is advisable to perform the leak test of the ampoules with the ampoule pointing downwards Melt sealing to be carried out even if it is not necessary to sterilize the ampoules or is not permitted, with lower levels depending on the ampoule content Temperatures are applied.

Thus, for the first time, the invention provides the possibility of all of the ampoule processing from the hut ampoule Individual treatments required until the ampoule is ready for sale, such as scoring, Breaking off the skewers, cleaning the inside, sterilizing, drying, gas pre-filling, filling, preheating or dampening, melting, printing, drying of fonts or burning-in of fonts, Sterilize, check for leaks, pack in a closed operation, avoiding them each intermediate handling or intermediate stacking, so that each ampoule only one once and no longer has to be picked up repeatedly as it used to be. In addition to the very large ones, by saving manual labor and significantly reducing waste achieved economic advantages and the elimination of the initially The above-mentioned levels are the highest guarantee for the perfect condition of all ampoules required.

Of course, it is possible, if necessary, to only process individual processes after the new one Process such as B. the printing to perform, especially since this is already compared to the previous working methods result in significant advantages.

On the other hand, other treatments can easily be carried out in the closed as needed Work step can be incorporated, for example the filling under neutral gas, the gas introduction at a special job to be arranged in front of the actual filling point Help is given to the hollow needles to be introduced almost to the floor, or to the filling point itself which gas and liquid are introduced one after the other through the same hollow needle. It can a concentric double pipe is also used for the simultaneous introduction of gas and liquid will.

The economy can be increased even further by the fact that the new process with a process for the production of the ampoules through direct attachment to this is combined into a coherent process.

If the melt burners are well adjusted, the new process melts the Ampoules flawless. When using very different glass thicknesses and properties Ampoules, the security can be increased according to the invention in that the Melting burner regulated automatically under photoelectric control of the melting process or be pivoted.

The new process can also be carried out in such a way that the ampoules for the operations in which they have to take a position deviating from the normal delivery position, e.g. B. for knocking off the spit, cleaning, drying, if necessary gas pre-filling and filling individually or clamped in groups on a carrier which can be rotated stepwise around a horizontal axis and be brought through this one after the other in the individual working positions.

The new method can advantageously also be carried out in such a way that the ampoules only inserted with its skewer in carrier with clamp mount and closed by their movement the individual workplaces and be brought into the correct working position. Will for each Ampoule uses a rotational body-like carrier and the ampoule is clamped centrally, so it experiences one revolution around its longitudinal axis when it is turned.

In this way it is possible to scratch the ampoule stick while the ampoule is rotating to be carried out with the skewer pointing downwards and also other work processes in this position, such as B. cleaning and drying to connect, whereupon the ampoule by pivoting movement its carrier is brought into the upright position required for filling. That too In this case, the ampoule can be melted shut in a vertical position while rotating be performed.

In the drawings are various embodiments of machines for exercising of the new procedure. It shows

Fig. Ι an ampoule support frame in front view, 2 shows the same frame in a plan view of the three ampoule support rails,

3 shows the same frame in cross section,

Fig. 4 is a schematic plan view of the guide tracks of a plant for processing of the ampoules in the supporting frames according to FIGS. 1 to 3, Fig. S lying between D and E of the installation according to Fig. 4 job for scribing ampoules in side view,

6 guide means for the ampoule skewers on the cutting element, in a front view,

7 shows the same guide means in a plan view, FIG. 8 shows a cross section through the work stations FM of the same system according to FIG. 4 with an indication of some devices in front of and behind them,

9 shows the work station for printing the ampoules between P and Q of the system according to FIG. 4 in a side view,

Fig. Ίο another version of a likewise; Plant working with support frames for processing the ampoules in a schematic perspective Representation omitting the drive mechanism,

Fig. Ii an embodiment of a stationary ampoule support rails and machine equipped with conveyor rails for processing the ampoules in a schematic perspective illustration below ίο omission of the drive mechanism.

Fig. 12 shows details of the machine according to Fig. Ii associated with turning means for knocking off the ampoules skewers with the means for adjusting the supporting elements for different lengths ammonium pulle ¹ S and thicknesses,

13 shows a horizontal rotating body with track sections evenly distributed over its circumference as a carrier for the ampoules, which are processed in various ways at the various switching points are subjected, in side view, Fig. 14 with a rotational body-like carrier an ampoule clamped in it with its skewer, viewed from below,

15 shows the same arrangement in the vertical Middle cut.

In the execution of a system according to FIGS. 1 to 9, the frame-like shown in FIGS. 1 to 3 is used Support frame 1 with the lower longitudinal rail 2 as a support for the ampoule bottoms. One tight Next to the lower longitudinal rail running intermediate rail 3 and the upper longitudinal rail 4 are with ten notches 5 for receiving the ampoule body and ten notches 6 for the Provide ampoule skewers. The end connecting webs 7 of the support frame 1 each have a hole 8. Is a clamping bracket that runs over the entire width of the frame and is provided with a flexible support 10 9 with resilient legs 11 on the support frame 11 pressed open, snap small suppositories 12 seated on the spring legs 11 into the Holes 8 and hold the clamping bracket 9 in place. As a result, the ampoules lying in the support frame 1 become held immovably.

There is also a T-shaped cutout 13 on each of the two connecting webs 7. With these The support frame 1 can slide cutouts 13 on correspondingly shaped guide rails 14 be moved.

Fig. 4 shows a schematic plan view of the arrangement of such guide rails for the ampoule support frames on a system for handling ampoules, which is either equipped with fully automatic drive and control means or - ■ with particular advantage ■ - can be operated semi-automatically.

The guide rails form a closed path, consisting of the path sections aa, bb, cc and dd, which are connected to one another by the transfer devices F, T, M and S. The ampoule racks walk through the entire system on this guideway. At workplaces A, B and C , empty, uncut ampoules are placed on the ampoule support racks located there in an upright position. In a manner to be described in more detail, when the support frames loaded with ampoules move through the system between D and E, the scratching takes place, with F the scratched ampoule skewers are knocked off, with G the interior cleaning, with H drying and, if necessary, sterilization of the empty ones Ampoules, with K the gas pre-filling (if necessary), with L the filling, between M and 0 the melting, between P and Q the printing, with R and ^ the writing on drying or burning and finally with 5 ¹ the expulsion of the ampoules. The positions of the operators required for semi-automatic operation are marked by I to VIII.

FIG. 5 shows a side view of how an ampoule support frame 1 is guided and held by a T-shaped guide rail 14 mounted on a stand by engaging in its cutouts 13 shown in FIG. 3. The inclined upright position of the support frame 1 resulting from FIG. 5 offers a secure hold for the ampoules lying on it. Between D and E of FIG. 4, a rotating friction wheel 15 provided with a resilient support is arranged above the ampoule path, whereby the respective ampoule below it touches and - lying in its support frame notches 5 and 6 - is set in rotation about its longitudinal center line. A diamond 16, resiliently mounted at this point under the path of the ampoule skewers, digs a scratch line 17 running all around in the ampoule skewer during the rotation of the ampoule. The locking screws 18 and 19 are used to hold the diamond set to the desired section length and pressure in position.

In order to push their skewers sideways against the diamond when the ampoules are brought up avoid, a guide piece 20 can be placed on the diamond 16, as in Fig. 6 in Front view and in Fig. 7 is shown in plan view.

In FIG. 8, which shows a cross section through the work stations F and M of FIG. 4 and also indicates some devices in front of and behind, F is a turning device for the carrier frame that has arrived at F on the path aa for transfer to the railway section bb. The turning device consists of a rotatable three-armed frame, on which each arm carries a guide rail 14 adapted to the length of the support frame. 8 shows, denoted by aa , an ampoule support frame 1 that has come from the scoring point in the oblique upright position of the web aa. At this point, a clamp 9 (Fig. 1) is placed on the support frame in order to secure the hold of the ampoule for future treatment. If the turning device is then rotated in the direction of the arrow, the incised ampoule skewers hit the stationary stop rod 21, which is provided with a flexible support. The am-

pullen arrive at the end of the turning step in the position designated bb with the skewer opening pointing downwards and are guided from there on the web bb to the work station G (FIG. 4). Under the ampoule group that has arrived there is a group of hollow needles 23 which is appropriately arranged on a supply pipe 22 and which are inserted into the ampoules well centered in the notches of the support frame by upward movement, whereupon cleaning fluid is injected through the hollow needles, to collect and discharge the Sheet metal channel 24 is provided. After lowering the needles 23 and forwarding the support frame to the drying point H (FIG. 4), hollow needles 25 arranged and moved in the same way are introduced there, through which air or hot air is introduced for the purpose of removing the rinsing liquid and for drying.

The ampoule support frame 1 now reaches the point / (Fig. 4), which consists of a turning device rotatable about the horizontal axis 26 (Fig. 8) and the ampoule support frame 1 is pivoted from the path bb by i8o ° to the path cc on which the Ampoule skewers point upwards. At the following work stations K and L , correspondingly arranged hollow needle groups 27 and 28 are provided above the ampoule groups for any gas pre-filling or filling that may be required.

After they have been inserted into the ampoules that are already in the center, they are filled in a known manner Way.

With the turning device M located at the next work station, the support frames 1 are swiveled out of the path cc into the path dd , where they again assume the oblique position they had at the beginning, in which the ampoules no longer need to be secured by a clamping device. The clamping bracket 9 is therefore removed here and handed over to the opposite work station F for reuse. At N (Fig. 4) the skewers of the ampoules can be preheated or steamed if necessary. Between N and O there is provided a device for melting ampoules, which, as indicated in FIG. 8 by dashed lines, consists of a friction wheel 29 and a burner directed at the spit opening while rotating 30 exists. If the support frame is conveyed step by step from the point M to O (FIG. 4), the filled ampoules lying on the frame are successively set in rotation and melted shut by this device. Instead of the one burner 30, ten such burners can be provided, and instead of the friction wheel 29, a friction belt which sets the entire group of ampoules in rotation can be provided.
On the way from P to Q (FIG. 4), the ampoules are printed by a device which is shown in FIG. A plate 35 is arranged movably up and down on a stand 34 carrying the guide rail 14 with the supporting frame ι guided thereon, on which a support plate 33 is arranged movably in the horizontal direction through prism guide 36 and carries ten pairs of resilient forks 31 and 32. When the plate 35 is lifted, these spring forks lift the ampoules somewhat out of their support frame 1, the spring fork located on the ampoule spike side not carrying the spit, but rather the upper end of the ampoule body. The lifted ampoules come into contact with a pressure or pressure transfer plate 37 which has previously been swiveled out and colored or printed. By moving the support plate 33 on the plate 35, the ampoules are guided along the pressure or pressure transmission plate 37 as far as is necessary for the rolling of the ampoules to receive the labeling intended for each ampoule. The support frame 1 has also been taken along by the tongue 38 seated on the support plate 33, so that when the plate 35 is now lowered, the printed ampoules are placed back in their notches on the support frame 1.

If the pressure range is greater than the distance between two ampoules, the support plate becomes 33 is equipped with five pairs of suspension forks instead of ten, and the printing takes place in the manner described in two groups, the first, third and fifth in the first step etc. ampoule is printed and in the second step the second, fourth, sixth etc. ampoule.

A wide variety of known direct printing processes or transfer printing processes can be used for the printing itself, which can take place not only on the way from P to Q but also during the standstill in P or Q.

Under R (Fig. 4) (and, if necessary, at workplaces that are still to be interposed) and possibly under 6 "are heat sources, e.g. small-flame burners or electrical heating devices, which have the purpose of drying or burning in the fresh lettering .

From R , the support frame 1 with the printed ampoules arrives at the transfer platform S, on which it is guided from the railway line dd back to the railway line aa. There the finished ampoules can be removed from the support frame 1 by hand, or the ejection can be done mechanically in that the ampoules are lifted through a corrugated sheet metal corresponding to their storage over the bottom rail 2 of the support frame 1, whereupon they by their own weight slide down and are passed through a chute, which is expediently also provided with grooves, into a collecting container or a transport device or also directly into the sales package, with the distance between the individual ampoules being reduced to the distance to be taken in the sales package by means of grooves tapering downwards.

The ejection of the ampoules can take place without a special mechanism even during the movement on the transfer table in such a way that a grooved plate protrudes from the path aa in the direction of bb to tongue-like, through which the ampoules lying on the carried frame ι are slipped out and on one . 'Get slide.

The now empty magazine comes from S on ίο the path aa to point A, where .es is loaded with new ampoules and its new cycle begins through the system, which in the illustrated embodiment (Fig. 4) requires fifteen such support frames.

Different sets of such supports can be used for different ampoule sizes or the support frames can be made adjustable. For adjustability to different Length is sufficient to subdivide the connecting webs 7 (Fig. 1) and make them extendible and to set up the intermediate web 3 to be adjustable for different ampoule thicknesses. It is also possible by inclined guidance of the connecting web parts 7 when they are pulled out not only the Abas stood between the rails 2 and 4, but also to change the position of the intermediate web 3 so that it is based on the larger diameter of the longer ampoule and also on the smaller diameter smaller ampoules.

If the support frames are conveyed and the work equipment is not operated mechanically, but by hand, which in the system shown as an embodiment in FIGS. 1 to 9 is expedient and also grants the special advantage that every work process, especially the scribing and melting, can be managed with observation control, 4 eight operators (I to VIII) are required in the system according to FIG Fetching and pushing the ampoule racks only a few steps to operate of the machining facilities.

This work does not require any special skill, and it can vary according to the pace of work the level of skill of the operators. It is useful that the operator, whose work experience shows that the requires most of the time (for ampoules with a large capacity, this is usually the filling point operating person V), the sign for further transport of the support frames by a signal all jobs.

With the system described, the operators can, even in semi-automatic operation achieve about ten times the performance that was possible for them in the previous way of working, because ten ampoules are treated at the same time with each work process in the new system. Even more important, however, is the qualitative improvement of the ampoules achieved by the new process and the substantial reduction in committee.

10 shows a further exemplary embodiment of a machine operating with support frames System. The support frames 51 correspond approximately the support frames shown in Fig. 1 to 3 1. You but do not require a hole 8 or a cutout 13.

The support frames 51 wander through in an uninterrupted manner Circuit the system, which consists essentially of two parallel 'railways 52 and 53 and each one connecting these railways Transfer platform 54 and an endless transport device 55. Both railways, which consist essentially of an angled guide rail, are inclined so that the supporting frames resting on it or sliding along it are necessary for the safe position of the ampoules Have an incline.

"The front rail track has a number of movable track sections that serve to support the Bring support frames from the rest position into the required working position.

The drawing shows such a point in time. The transfer table 54 had a support frame 51 with empty, Uncut ampoules brought into the extension of the front rail track 52, whereupon all supporting frames on this track have been pushed to the next work site. Now is located the transfer platform is empty, i.e. without a support frame on the way back to the rear transfer platform 53.

At the point a! nothing happens to the ampoules that have just been brought in from the transfer table. Any missing ampoules can be added here.

At b ' the ampoule skewers are cut off. The rail track section 56 is mounted pivotably about a shaft 57. On the same shaft, two arms 58 can be pivoted and displaced in the direction of the shaft, and they carry a pressure plate 59 provided with a flexible support; In the rest position, the track section 56 is folded up so that an ampoule support frame can move from af to b ' . The pressure plate 59 is then lifted so far that "the transport of the carrier frame is not hindered. After the transport has taken place, the pressure plate 59 lies firmly against the carrier frame and holds the ampoules immovably. Then the entire" track section 56 "including the carrier frame 51 inclines 59 into the working position shown in the drawing, with the ampoule skewers pointing downwards at an angle.

The further work process at the cutting point b ' is as follows: The pressure plate 59 slides, guided by the arms 58 on the shaft 57, to the right and takes it through the. behind the support frame 51 engaging driver 60 also the support frame 51 with the ampoules. The ampoule skewers slide along the chamfering stone 61 which is mounted behind the ampoule track and which is pressed against the skewers by the spring 62 and scratches them. Behind the spikes the now arrived on the right side of the railway section 56

The stationary stop rod 63 is located in the ampoule group. If the track section 56 moves upwards again into its rest position, the skewers push against the rod 63 and break off at the scratched point. In order to achieve good break points, it is useful to mount the skewers somewhat elastically not far from the score, which can be done by pivoting a rail 64 provided with a flexible support before the upward movement of the track section 56 begins. The broken skewers fall into box 65. Any splinters cannot get into the interior of the ampoule because the ampoule opening points downwards at an angle at the moment of breaking off. As soon as the track section 56 has reached its rest position at the top, the pressure plate 59 moves a little further upwards so that the support frame with the cut ampoules can move unhindered from V to c ' during the following transport frame transport. During the transport of the support frame, the pressure plate 59 slides on the shaft 57 to the left again, in order to then be able to carry out a new work process with the next support frame 51.

As the drawing shows, the support frame 51 which has arrived in c 'has already been pushed further into a cleaning device immediately after its arrival, namely by a slide 67 movable on the fixed rail section 66 Continuation forming plate 68 get, and at the same time the ampoule skewers have pushed over ten hollow needles 69. Then a rubber-padded pressure plate 70 has placed itself on the ampoules and with its holding lugs 71 grips under the support frame, so that the slide 67 is no longer needed for support, but can move back.

In the cleaning drum 72 are several, for example six to twelve plates 68, hollow needle series 69 and pressure plates 70 mounted on a hollow shaft, which around the stationary shaft 73 is rotatable. The contents of the drum rotate after each loading with an ampoule support frame with all supporting frames located in it by one step upwards. Each in the top or the second or third from the top position, i.e. with the opening pointing downwards is sprayed out with hot water or some other rinsing liquid that passes through the connecting piece 73 in a channel of a bearing designed as a stationary cock plug for the hollow shaft and is further fed through the hollow needles located on the hollow shaft. Suitable Collecting sheets within each chamber of the drum ensure that the rinsing liquid is drained off below. With the further downward movement of the ampoule group, the ampoules move steadily with it Blow through a stream of hot air that enters on the other side of the hollow shaft and also is passed through the hollow needles and is used for drying after the rinsing liquid has been squeezed out.

Immediately after each step movement in the drum, i.e. each time a cleaned group of ampoules arrives at the drum exit point, the slide 67 moves up to the support frame 51, and the pressure plate 68 lifts off the support frame, so that with the now following downward movement of the slide 67 the support frame with the cleaned ampoules follows. The immediately following transport of the carrier frame brings the cleaned ampoules from c ' to d' and a new carrier frame from b ' to c' so that the pusher 67 can immediately load the vacant position in the drum with a new carrier frame. .

At the workplaces d ' and e' , the ampoules are pre-filled with a neutral gas and the actual filling is carried out. In order to be able to carry out the filling expediently in the vertical position, a track section 75 which can be pivoted from the vertical rest position to the inclined working position about the shaft 74 extends over both work points d! ', E'. A pressure plate 76 provided with a flexible support is also around the shaft 74 is pivotable and resiliently mounted so that the support frame can be transported unhindered in the rest position, but when the track section 75 is pivoted up, the ampoules are immediately applied and pressed against the pressure plate 76. The ampoules, which are pressed firmly into the support frame notches in this way and are thereby centered, now allow the hollow needle to be inserted properly. While at the gas pre-filling point d ' all hollow needles yy can be stored and inserted together and also have a common supply line, at the actual filling point e' separate supply line from the individual "o not shown metering devices (pump or the like) is required because of the individual metering required here. It is also necessary to avoid loss of liquid and soiling of the machine in the event of missing or faulty ampoules. For this purpose, each filling needle 78 is connected to a guide rod (not shown) that only activates the filling device when it has reached its lowest position There are also ten resilient metal sheets 79 on the pressure plate 76 at e ' , which are pushed back by the ampoule skewers when the ampoules are pressed against the pressure plate 76. If an ampoule is missing (fourth position from the left in the drawing), that remains Spring steel sheet in its position, thus hiding the point where the ampoule spi would otherwise be would be. The filling needle arriving here cannot lower itself any further, and the guide rod does not activate the filling device. The same thing happens if another obstacle, for example too narrow a spike or a too narrow constriction of the ampoule neck, prevents the full penetration of the needle into the ampoule interior.

At work point f , the ampoule skewers can be pretreated for melting by preheating or steaming off.

At the melting point g ^f , the ampoules are rotated around their own by an endless, very pliable (sponge rubber or the like) band 80. Axis set, while flash flames 81 S brush their skewer openings and melt them. At hf , the ampoules are printed, expediently using the transfer printing process, by rolling the ampoules on an elastic transfer printing plate 82 which is previously printed by a printing forme (not shown) and which can be pivoted ^{about the shaft 82 a.}

When the circumference of an ampoule to be printed is larger than the distance between two ampoules from each other, printing takes place in two departments.

For this purpose, a plate 83 is arranged under the rail track and parallel to it, which carries two rows of five forks 85 resiliently mounted in sleeves 84. This device corresponds to that already shown in FIG. After printing in two departments, the ampoules are placed on their support frame at point i '. There, for example, ampoules that have not been found to be satisfactory can be separated out before they reach the sterilization device k ' .

The sterilization device k ' consists of a several meters long, optionally double-walled chamber 86 with an inlet opening 87 and an outlet opening 88 for the ampoule racks, provided with heating devices, thermoregulators and possibly air movement devices and insulated against heat dissipation to the outside. An endless transport device 55 runs in the chamber 86 and carries a number of holding sleeves 89 for the ampoule support frames, which number of holding sleeves 89 is adapted to the hourly output of the system and the required sterilization time.

The holding sleeves 89 are bent from sheet metal in such a way that they encompass the support frame pushed in from i ' on the back and hold the ampoule body just above the bottom and the ampoule necks at the constriction or taper on the front, but without closing the place provided with the fresh imprint touch.

In these holding sleeves 89, the support frames with the ampoules migrate through the sterilization device, namely after the soon-to-be turn at the front end of the chamber 86 initially of the lower track j with the spear pointing downwards. Due to the shape of the described Holding sleeves 89 protect the ampoules from falling out. Due to the heat inside The sterilization chamber is achieved in three ways: firstly, sterilization, secondly, the Scripture, thirdly, density test, because because of the hanging position_ empties as a result of the higher, with the internal pressure resulting from the sterilization of every ampoule, even the finest leak fio has. The squeezed-out liquid can be caught by collecting devices provided for this purpose and, if necessary, reused be derived.

After the ampoules, which are now standing upright, have passed through the upper track, the support frame with the ampoules is pulled or pushed out of the holding sleeve 89 through the outlet opening 88 and guided onto the first section V of the rear rail track. There only the empty ampoules are separated out, because every ampoule that comes out of the sterilization device is to be regarded as perfectly sterilized and leakproof.

That is why packing can follow immediately at mf. A sheet metal 90 which is corrugated in accordance with the ampoule spacing and is mounted parallel under the track section rises through the support frame located there. The ampoules lifted out of the support frame now slide downwards and can, if necessary, be conveyed directly to the box through a chute 91 which narrows the ampoule spacing in the support frame to the ampoule spacing in the shipping box. Any packaging mechanisms that may be required can also be connected directly, for example a device that turns every second ampoule, which can already be done by appropriate design of the sheet 90.

In order to avoid "subsequent addition of incompletely filled boxes, it is advisable to immediately fill the gaps that arise when rejecting empty ampoules at / 'from a stock of flawless ampoules kept ready. For this visibility, it is advisable to have two or better three stations available , So / ', m', n '. The packaging point, which was only placed after ruf for the sake of clarity in the drawing, would come after 0'.

The following locations up to u ' are used to load the empty support racks 51 with new ampoules by hand or by mechanical devices. To make it easier to insert, corrugated metal sheets, similar to sheet metal 90, can be attached under the track sections, which, when the support frames are at a standstill, rise so far that they protrude slightly beyond the notches in the support frames. The support frame that has arrived at u ' begins its new cycle by being pushed onto the transfer table 54. no

Substances such as morphine solutions that are sterilized a second time after an interval have to be, can be expediently slide into collecting containers at the packaging point so that they machine-packed from these collecting containers after the second sterilization that takes place therein can be. ·

If sterilization is not permitted or not necessary, the transport device 55 in the chamber 86, which in this case is little or not heated, can (if the sterilization device k 'is present) run in the opposite direction, so that the support frames on the short distance from 87 directly to 88 arrive, or, if sterilization is never an option, the sterilization or transport device 55 can continue.

can be left, in which case a transfer platform of the type of transfer platform 54 to connect i ' and /' would have to be attached instead. To dry or burn in the writing, a heating device (most expediently open flame) would have to be attached under f and / '.

However, if a sterilization device k ' is connected to the system, it is recommended to use it even if sterilization is not required.

that is or is not permitted, just to check the density. In this case, the temperature is only allowed be so high that the ampoule filling is not adversely affected, in which case it would be sufficient that leaky ampoules are only partially emptied in order to identify them as leaking and to separate them.

Similarly, other parts of the system can also be left unused, be it that the workplaces are idle or that they are put out of operation. For example, when using ampoules that have already been opened, the device V can not be folded down. If the inside of the ampoule does not need to be cleaned (e.g. for ampoule fillings for

* 5 technical purposes), only the slide 6γ is shut down , etc. The system can also be built from the outset without unnecessary equipment.

On the other hand, the new process easily allows the integration of further work processes. For example, the cleaning and drying drum can be made larger or equipped to form an endless belt, or it can, for. B. for serum works in front of the filling device a Sterilisiereinricbtung (similar to k ') can be provided for the empty ampoules.

In the drawing, the system is shown for the sake of simplicity for a specific ampoule size. When processing several ampoule sizes, one becomes the system for the largest ampoule set up and for the other varieties either different support frames or adjustable ones Use support frames.

Fig. 11 shows an embodiment of a Machine equipped with storage and conveyor rails for handling ampoules in a schematic perspective view - omitting the drive mechanism.

On inclined racks 101, 102, 103 are parallel rails 104, 105, 106 arranged, which are used to store ampoules in an inclined position. The bottoms of the ampoules rest on the rail 106; the ampoule body are a few millimeters above the floor in notches of the rail 105 and the skewers about 5 to 10 mm below the future melting point held in notches in the rail 104.

On stored on racks 101 and 103 Crank arms 107 and 108 are another pair of rails through the intermediary of stones 109 and 110 suspended in, 112 swinging, the same Has notches like the pair of rails 104 and 105, but with a slightly smaller gap. If the cranks 107, 108 turn in the direction of the arrow, the pair of rails leads in and 112 a circular motion and detected before reaching the highest position between the Pair of rails 104 and 105 with its notches in the notches of pair of rails 104 and 105 lying ampoules, lifts them out and guides them to the next or (in the drawing Example) the next but one notch of the pair of rails 104 and 105, where they are placed while the Pair of rails in and 112 continues its downward movement. The rail 106 must be so high that the ampoule bottoms even in the highest position of the pair of rails in 112 and 112 are still in contact with it. With each turn of the crank, all of the ampoules lying on the rails 104 and 105 are therefore removed promoted to the next job. In the example shown, each job is for set up two ampoules, but it is also possible to use them for several ampoules or for to provide only one.

. The ampoules are now partly during their storage in the notches of the pair of rails 104 and 105 (or corresponding other rail sections), partly during the further conveyance, i.e. during their storage in the notches of the pair of rails in 112, subjected to the individual operations. In the first conveying step, i.e. on the way to b , the uncut ampoules inserted by hand or by machine at α are passed under the resilient pressure plate 113 mounted on the frame 101, on which they lie in the notches of the pair of rails in 112 , unroll. A hollow rod 114, which runs parallel to the ampoule layer, is attached to the frame 101 and carries a rod 116 which can be locked by means of an adjusting screw 115 and at the ends of which a leaf spring 117 is attached, which in turn carries a carborundum prism 118 or some other scratched glass instrument at the end. The setting screw 115 is used to set this scoring device in such a way that it hits the ampoules rolling under the pressure plate 113 at the desired cut-off point and with the most favorable scoring pressure determined by a few samples for the respective type of ampoule. As a result of the rolling of the ampoules under the pressure plate 113, the ampoules receive a score running around their stick circumference in this way. The job c consists of a turning device for the ampoules in order to be able to knock off the end of the skewer at the scratching point with the skewer pointing downwards or diagonally downwards, so that no glass splinters get into the ampoule opening. A square 120 is rotatably arranged around a shaft 119 mounted in the frames 101 and 102 and is set in the rest position in such a way that one of its surfaces forms the continuation of the rail 106. A rail 121 attached to and close above it and provided with two notches forms the continuation of the rail 105 and another notch attached to the square 120 through the intermediary of the bracket 123 and holder 124

rail 122 the continuation of rail 104. - In the rest position becomes a direct one through this movably mounted rail section 120, 121, 122 Continuation of the fixed rail track 106, 105, 104 is formed. The opposite Side of the square 120 also carries rails 121 and 122, so that each time the ampoule is changed only one rotation of the square 120 by 180 ° is necessary is.

To hold the ampoules in place while they are being turned, the following 120 are provided on both sides of the square Facilities provided: A rod 125 runs through the square 120, which on the one Side a roller 126 (or 126 '), on the other side a hollow support rod 127 carries and through a (invisible) spring is pushed backwards. On the support rod 127 is one in their Longitudinal direction and pressure plate 128 which is displaceable against it and which can be locked by means of an adjusting screw for the ampoule body and a resilient one that can be displaced and locked in the holding rod 127 Print bar. 129 attached, which lies against the ampoule skewers just below the scratch and serves as an elastic abutment when knocking off the end of the spit. Below the rail in a piece of angle rail 130 is attached to this so that it is when the upward movement of the The pair of rails 112, 111 meets the roller 126 and thus the rod 125 together with the clamping devices 128, 129 lifts off the ampoule so that the ampoules can then be transported further can take place unhindered.

Immediately after the new ampoules, which have arrived at c , have been deposited, the angle rail 120, which is lowered again with the pair of rails in 112, releases the rod 125 with the clamping devices 128, 129 again, so that the new ampoules are clamped. If the turning device now rotates around the shaft 119 by 180 °, during this movement the ampoule skewers hit against the stop rod 131, which can be adjusted to the desired break-off length on the frame 101, whereby the ampoule skewers break off at the scoring point and fall into a box (not shown).

At the next turn of the turning device, the cut ampoules come back to their starting position and in the next conveying step they move to d, while new, unabgesdittenen ampoules come from b to c .

The gas pre-filling and filling of the ampoules takes place at work points d and e. These two working positions are combined and mounted with their base support 132 so that they can be pivoted about the shaft 119 from the normal position into the vertical position and back. In its rest position (i.e. in an inclined position), the upper surface of the base support 132 forms the continuation of the rail 106 or the square 120 and the rails 133, 134 the continuation of the rails 105, 106 or the rail sections 121, 122. The rail 134 is attached to the base support 132 through the intermediary of the bracket 135 and the holder 136.

As with c , also with d and e , pressure plates 137, 138 attached to rods 139, 140 with a common roller 141 are used, which are influenced via roller 141 and rods 139, 140 by the above-mentioned angle rail 130 attached to the rail to clamp the ampoules.

Are located at the filling point e on the pressure plate 138 is still serving as a button spring plates 142, τ %% When pressing the pressure plate 138 against the vial body 143 push the push-button panels 142, against the ampoules skewers and bend back (142). If, on the other hand, an ampoule is missing, they cover 143 the notches in the rail 134. Above the work points d and e , a needle holding device 144 is arranged so that it can be raised and lowered. The hollow needles 145, 146 for work point d are connected to a common feed connection 147 through which carbon dioxide, nitrogen or another inert gas can be fed. The hollow needles 148, 149, on the other hand, can slide in the needle holder 144 and are each connected to a guide rod (not shown) and to a metering device (not shown) (pump or the like). When the hollow needle holder 144 is lowered, the hollow needles penetrate through the skewers, which are already centered in the notches, into the inside of the ampoule, and gas is blown in at d and liquid is injected at e through the hollow needle guide rod in its lowest position (for example by engaging a connecting link in the pump drive). If, however, an ampoule is missing, the hollow needle can only lower itself down to the feeler plate 143 at this point, and the needle guide rod, which has now not reached the extreme low position, does not start the metering device. This avoids loss of liquid and contamination of the machine.

After the hollow needles have been lifted by the needle holder 144, the entire device of the work stations d and e located on the base support 132 is swiveled back into the rest position, whereupon a new conveying step takes place in the manner described.

A fixed rail track 104, 105, 106 begins again at /. At this point / can, if necessary, preheating by burners (not shown) the ampoule skewers or by steaming out of fine nozzles the steaming of the Ampoules.

g is the melting point. On the frame 102, a base support 151, which is pulled down by spring force and is lifted up on the rail in the step of conveying the ampoules by an angle rail 150 attached to the rail, is mounted so as to be vertically displaceable Turn the ampoules at g. During this rotation, jet flames from the burners act on the end of the ampoules

9-33 70Ö

154 go out, which are adjustable in height on the frame 102 (Screw 155) and pivotable (screw 156) are arranged.

When passing through the now following job h , the ampoules are printed by rolling (similar to a) under a transfer printing plate 157, which is pivoted in bearings 158 and periodically with each pivoting back (position of Fig. 11) by a printing unit (not shown) is printed in one or more colors. The working setting of this transfer printing plate 157 takes place at such a height above the ampoules that each of the two ampoules only touches the plate 157 a little longer than is necessary to receive the printed text, that is, each of the two ampoules does not roll on the whole Plate 157, but only on the part intended for its imprint. Since differences in diameter of the ampoules would have an unfavorable effect on the printing result, the notches on the pair of rails in, 112, which are used for transport over this distance, are resiliently formed by resilient mountings 159. At the points k and /, weak flames directed at the ampoule body from the burners 160 cause the imprint to dry out or burn in quickly.

After the finished ampoules still have the

Have passed through point m , they get close-Hch at the last conveying step to n, where they are no longer stored in notches, but reach the ends of the rails 104, 105, 106 designed as an inclined plane, from which they are in a collection container or on unroll another facility serving for further processing.

It is not difficult to incorporate any additional processing points that may be required or to connect, for example a device for clamping ampoules can be incorporated be, the ampoules are heated in a known manner on the neck and touched with a cooling ring to through the on the Voltage generated at the point of contact later opening of the. Ampoules for use facilitate. Also for the uninterrupted passage of ampoules through a sterilization device, z. B. sterilization chamber, the method of conveyance described here by means of notch rails to serve. You can simply lengthen the conveyor or, even more appropriately, a conveyor Connect with even smaller gaps, alternating with the pair of conveyor rails in, 112 working, each the last ampoules lying on the rails 104, 105, 106 decreases. Conversely, the machine can also be used with a machine for producing ampoules Glass tubes are connected so that the work process extends from the glass tube to the finished one and printed ampoule extends without intervening.

A machine device according to the invention is particularly suitable for Processing of different sizes of ampoules, since mainly only the storage and Conveyor rails and the clamping devices need to be adjusted. Most of the pretensions requires the turning device. This is shown in Fig. 12 in side view, the same time also shows a side view of the conveyor rails. Here the cranks 107, 108 have with the Pair of conveyor rails in, 112 is the highest Position reached and thereby the ampoules in the conveying step furthest over the bearing rail 104, 105 or here 121, 122 lifted out and the Clamping devices 128, 129 by pushing up the rod 125 provided with roller 126 through the angle rail 150 attached to the rail lifted up.

Each of the two cranks 107, 108 carries one Stone 109, 110 on which the conveyor rails 111, 112 are attached with the aid of the racks 161, 162. The conveyor rail 111 is through the rack 161 for different ampoule strengths, the conveyor rail 112 through the rack 162 for different Adjustable ampoule lengths. The adjustment is carried out by gears 163, 164, which are used to uniform adjustment of the entire rail 111 or 112 by a long one, from stone 109 to Stone 110 running shaft 165 or 166 with each other are connected. The hand screw for shaft 165 is on stone 110, the hand screw 167 for shaft 166 on stone 109.. The adjustment of the bearing rail 121 to different Ampoule strengths are made by direct displacement in square 120. The displacement the rail 122 to different ampoule lengths is done by moving the retaining bracket 123 in the holder 124 and tightening with the clamping nuts 168.

The pressure plates 128 can with their bearings 169 on the holding rods 127 in their longitudinal direction and with the help of the journals 170 going through the bearings 169, they are also displaced against them will. The screws 171 are used for fixing. The pressure strips 129 are with their support arms 172 arranged displaceably on the support rods 127 and lockable by means of screws 173. 13 shows a pentagonal rotating body 180 rotatable about a horizontal shaft 181, each side of which is similarly equipped as each side of the turning device shown in FIG to knock off the ampoule skewers. There are therefore mounting rail sections 121 and 122 of brackets 123 and pressure plates 128 of movable Support rods 127 held.

The ampoules are fed and passed on in the upright position at point U by a pair of conveyor rails in, 112 in the manner already described, during which time the pressure plate 128 is lifted. During the remaining ampoule handling processes on the rotating body 180, the ampoules are held in place by the pressure plate 128.

At the switching points V, W, X, Y , corresponding hollow needle groups are movable in this way with respect to the skewer openings of the ampoule groups

stored so that they can be introduced into the ampoule groups during the standstill.

The ampoules, which have already been scored at U, hit the stationary rod 131 with their skewers during the rotary movement of the rotary body, causing the skewers to break off. At V the ampoules are cleaned by injecting a cleaning liquid through the inserted hollow needles 182 and at W dried through the hollow needles 183. At X, drying can be continued through the hollow needles 184 or a neutral gas can be introduced. At Y , the hollow needles 185 are used to fill the ampoules. With the next step movement, the ampoules come back to point U, from where they are passed on by the conveyor rail pair 1.11, 112 to the melting point, etc.

The rotating body 180 can, for example, be provided in place of the devices at the work stations c, d and e of the system shown in FIG. 11. It not only replaces these facilities, but also allows the ampoules to be cleaned and dried in addition to that system. Such a rotating body 180 can also be equipped with guide rail sections (similar to 14 or 52) for ampoule support frames instead of support rail sections for the storage of ampoules, the feed and forwarding of the support frames also taking place at U by hand or mechanical devices.

The step-by-step switching of the rotating body 180 can, for example, by one on one of its Five-star Maltese cross attached to the side walls and the simultaneous movement of the pressure plates 128, for example, by one provided on the shaft 181 that is stationary in this case Curved path take place.

The entry and exit of all hollow needle groups 182 to 185 can be controlled jointly will.

If such a rotating body 180 is designed for the use of ampoule support frames, it can, for example, replace all work stations from F to M of FIG. 4 in the system shown in FIGS. 1 to 9.

A system according to FIG. 10 could also be simplified in that instead of the scoring and breaking device V shown there, a scoring device without pivoting the guideway is provided and the devices at c, d ' and e' are replaced by the rotating body 180.

For further required treatments, the rotating body 180 can also be used for the attachment of any a larger number of jobs are to be set up.

In Fig. 14 is a view from below and in Fig. 15 shows a rotational body-like carrier 190 in the vertical center section, in which the Ampoule with its skewer inserted centrally and held only by clamping the skewer will. A hole 191 is provided for this purpose, that in an angled or semicircular | shaped, intended to receive the ampoule skewer Stop 192 runs out so that the center of the clamped ampoule is located exactly in the center of the solid of revolution. The entrapment is done by a Pressure body, in the example shown by a leaf spring 193 inserted into the hole 191, the presses against the inserted ampoule skewer. Stop 192 and leaf spring 193 are useful The taper of the ampoule skewer is tapered accordingly and at the top for relief the introduction of the skewer somewhat expanded.

The rotational body-like carriers 190 can be on suitable documents from work to Job, are promoted, for example on angle rails 194 or on U-rails 195. At Use of a pair of U-rails 195 can by pivoting the relevant track section of the carrier 190 and thus the ampoule be brought into any desired position so that the ampoule held in the carrier 190 is well centered is in a job-appropriate position at every job. The ampoule can also be replaced by a the rotating body in rotation device in rotation about its longitudinal center line be brought, both with skewer setting downwards for the purpose of scoring as well as with the skewer position upwards for the purpose of Melting down.

It is expedient to initially only insert the ampoules with their skewers into the carrier 190 a little and they only during their conveyance through a suitable slideway for the ampoule bottoms or push it in during the standstill using a mechanically moved device to let that all ampoules get exactly the same length when scratching.

To use the same carrier 190 for ampoules with very different skewer diameters To be able to, it is useful to set up the stop 192 radially adjustable so that the ampoule skewers after the stop 192 has been set accordingly, it is always centered on the rotating body be pinched.

A system for treating ampoules using such rotational body-like carriers 190, for example, would require two parallel rail tracks at both ends are connected by a turning device that enables rotation by 180 °. on the one The ampoules are inserted with the skewer facing downwards, at the next work place below Rotation of the carrier 190 scored, canceled, at the next two workplaces by by Hollow needles introduced below, lined up and dried, and then opened by the turning device brought the other lane on which it was pre-filled with the skewer opening, filled and then be melted shut with rotation. The ampoules " pushed out downwards, whereupon the empty carrier 190 by the turning device again on the another train is brought.

It is also possible for a plurality of supports 190 in the form of rotational bodies to be combined to form a group be stored a carrier that the system just described in a similar manner as the can go through ampoule racks described earlier.

For ampoules with a small skewer diameter, both when scratching and when melting can be dispensed with rotation, the ampoule skewers can be in strip-like, with Clamping devices for the skewers provided carriers and held in groups from work to Job to be promoted. In this case, the scoring is done with a downward facing Skewer, renouncing rotation, by guiding the carrier along with its group of ampoules a scoring device. For melting the ampoules, use the skewer pointing upwards if there is no rotation, it is advisable to use jet flames acting on the spit openings from two sides used.

The new method for processing ampoules explained by some exemplary embodiments is made possible many other designs and depending on the type of ampoule to be processed or similar containers and varies accordingly depending on the particular treatments required and be expanded. In any case, the new process not only increases the substantial, economical The advantage of saving manual labor and reducing the previously high level Loss of ampoule glass and filling material is achieved, but it is due to the new process for the first time The greatest possible guarantee that the ampoules to be dispensed are free of insoluble ones and soluble ingredients. In addition, there are the advantages of reliable tightness the ampoules tested according to the new procedure and the exclusion of the risk of confusion, by also labeling the ampoules in the same operation.

Claims (63)

Patent claims: 1. A method for processing ampoules od. Like., Characterized in that the ampoules individually or in groups with constant storage of your skewer on a carrier continuously from job to job are promoted and so by the sponsor at every job, avoiding special Adjustment measures get the correct position required for processing. 2. The method according to claim 1, characterized in that that the ampoules on one of them against lateral or longitudinal displacement securing, but their rotation about their longitudinal axis permitting support conveyed lying and any required change of position only on or shortly before this change of position conditional job experience, with processing depending on the requirements of the work process during standstill or while the ampoules are being conveyed he follows. 3. The method of claim 1 or 2, ^DA: characterized by that the vials in an upright position with their bodies inclined close above the bottom and with its spit far below the melting point in the future depending on a fork or notch and with its bottom at conveyed lying on a retaining wall and at which workplaces requiring a different position are transferred into this work position by movement of the carrier or its support, whereby they are protected against falling out or shifting by a clamping device. 4. The method according to claim 1, 2 or 3, characterized in that the grouped together Ampoules remaining in the same notches of the same carrier, which holds a certain number of ampoules this will be promoted to the individual jobs, after which the carrier will be promoted is transported empty to the exit point. 5. The method according to claim 1, 2 or 3, characterized in that the on a frame As a carrier lying ampoules by an expediently also with notches od. The like. Provided Conveyor lifted out of the notches in the frame and after each conveying step be placed in other notches in the frame. • 6 .. Method according to one of claims 1 to 5, characterized in that the movement the ampoule carrier or the promotion of the ampoules lying on the racks and their storage on other frame sections takes place on a circular path and that the transfer the ampoule carrier or frame sections in the respectively required other working position during the standstill the relevant jobs or beforehand, for example through a curved path, during the Promotion is made. 7. The method according to any one of claims 1 to 5, characterized in that the promotion of the ampoules or their carrier on a or several straight paths and that the transfer of the ampoules into the relevant Working position or the transition to another track with the help of movable sections a path is carried out. 8. The method according to any one of claims 1 to 7, characterized in that the on Their carrier lying ampoules by a friction wheel, endless friction belt or the like Purposes of scoring their skewer are set in rotation about their longitudinal axis and that the ampoule skewer is resiliently touched at the same time by a scoring device. 9. The method according to claim 8, characterized in that the scribing of the ampoule 933 70a skewers takes place during the promotion, with the ampoules lying on the carrier at one stationary elastic friction surface rolling off and at the same time with their rotating skewers resiliently mounted scoring device ■ tend to be guided along. 10. The method according to any one of claims 1 to 7, characterized in that the ampoules lying on their carrier are held by a clamping device / and, advantageously brought down or obliquely downward beforehand with a skewer position, are guided along a scoring device for the purpose of scoring or the scoring device is guided along the ampoules.
"11. The method according to any one of claims 1 to 10, characterized in that the breaking off of the scored ampoule skewers after clamping the ampoules on their carrier, expediently with the skewer pointing downwards ■ during the standstill by a hammer or during the pivoting movement of, for example Ampoules stored on a turning device are carried out by pushing the skewer against a stationary stop. 12. The method according to claim 11, characterized in that that the ampoules close to the breaking point to absorb the breaking blow and resiliently supported by a movable abutment to avoid splinters will. 13. The method according to any one of claims 1 to 7, characterized in that for the purpose of internal cleaning in those lying on the carrier and held centered in the frame notches by a clamping device, with ampoules pointing downwards or obliquely downwards without further preparation Cleaning needles are inserted through which one or more cleaning fluids Od. Like. Are injected and that through the same or different hollow needles the same or finer later job air or hot air for the purpose of pushing out liquid residues and drying are initiated. 14. The method according to claim 13, characterized in that that steam or hot air is introduced in the same way for the purpose of sterilization. 15. The method according to any one of claims 1 to 7, characterized in that the ampoules at the filling point by a clamping device are held in the carrier and by moving the carrier or its base be pivoted into the upright filling position, in which the filling needles without further pre ■ preparation into 'the inside of the ampoule. 16. The method according to claim 15, characterized in that that when erecting the ampoules at the filling point by applying the ampoule skewers against moving buttons the filling 'mechanism with its drive in connection is brought. 17. The method according to claim 16, characterized in that that at the filling point by the ampoules a locking member for the filling needle is pushed into the release position and when full 'When the filling needle descends, the filling mechanism is set in motion by its guide rod will. 18. The method according to any one of claims 1 to 7, characterized in that the ampoules in their normal at the melting point Inclined upright position, which they occupy in the promotion, remain in the notches of the carrier and only from a friction wheel, an endless friction belt or the like in rotation about its longitudinal axis offset and melted shut by brushing their skewers with one or more burners will. 19. The method according to claim 18, characterized characterized in that when a melting burner is arranged for a group of ampoules these individually passed the burner will. 20. The method according to any one of claims 1 ■ to 7, characterized in that the printing of the ampoules is carried out during a conveying step by placing the ampoules lying in the carrier notches under a Printing plate or a pressure transfer plate that has been previously printed in one or more colors rolled off and provided with the label. 21. The method according to claim 20, characterized in that that the ampoules during the pressing of spring-loaded forks "or notches and carried by the fork to be placed after the skewer instead of on the skewer the upper end of the ampoule body. 22. The method according to claim 21, characterized in that that the ampoules during their conveying step for the printing process only over the area of the inscription with the Pressure or pressure transfer plate are brought into rolling contact. 23. The method according to claim 22, characterized in that the ampoules during their Funding step for their printing to be moved on a circular path, which both the Length of the conveying step and the rolling length is adapted. 24. The method according to claim 21, characterized in that that in cases where the area to be printed on the circumference of the ampoules is greater than the distance between two ampoules, every second ampoule of an ampoule group lifted over the other ampoules of the same group and rolled under the pressure plate, taking their carrier with them is followed by the other ampoules of the same group in the same way over the first lifted out the printed ampoules and can be printed by rolling on the printing plate. 25. The method according to claim 21, characterized in that that the ampoules lying on a carrier and expediently in resilient forks by rolling over them during the standstill a pressure or pressure transfer roller or sliding over a pressure or pressure transfer plate are printed. ίο 26. The method according to any one of claims 20 to 25, characterized in that the imprint of the lying in the carriers and on or with these further conveyed and freely accessible ampoules through heating devices, such as B. by weak flames touching the ampoule body, dried or burned in before the ampoules Leave the system. 27. The method according to any one of claims 1 to 25, characterized in that the ampoules after their processing by lifting them out of their carrier over a, if necessary, the Slide into collection or transport containers to reduce the distance between the ampoules or transport equipment or directly into the sales package. 28. The method according to any one of claims 1 to 12 or 15 to 18, characterized in that that the ampoules are scratched individually or in groups in a continuous operation, opened, filled and closed. 29. The method according to claim 28, characterized in that in the contiguous The operation also includes interior cleaning, drying and, if necessary, sterilization of the empty ampoules is switched on before they are filled. 30. The method according to claim 28 or 29, characterized in that in the contiguous The process also includes printing and subsequent drying or baking the labeling is switched on. 31. The method according to claim 28, 29 or 30, characterized in that the finished filled Ampoules through a sterilization chamber following the related work step by means of the same conveying device or the like. Funded or mechanically to another, by a sterilization chamber or a Transport device leading to the sterilizing bath. 32. The method according to claim 31, characterized in that that the sterilization in the sterilization chamber at permanent or intermittent after carried out downwardly directed fusible link and as a result of the temperature increase increased internal pressure, even with the slightest leak in the fusible link the contents of the ampoule and thus a leak test is carried out. 33. The method according to claim 31, characterized in that that the leak test is carried out with the fusible link pointing downwards even if the Ampoules are not required or not allowed, where appropriate according to the Ampoule contents lower temperatures can be used. 34. The method according to any one of claims 1 to 33, characterized in that all of the Ampoule processing from the hut ampoule to the ready-to-sell ampoule is required Individual treatments, such as scoring, breaking off the skewers, cleaning the inside, sterilizing, Drying, gas pre-filling, filling, preheating or evaporation, melting, printing, Font drying or font burning, sterilizing, leak testing, packaging in a closed operation, avoiding any intermediate handling or intermediate stacking be performed. 35. A method for treating ampoules according to any one of claims 1 to 34, characterized in that that there is a process for the production of the ampoules through direct attachment to this to form a coherent one Procedure is united. 36. The method according to any one of claims 1 to 7, 18, 19, 27 to 35, characterized in that that the melting burner automatically under photoelectric control of the melting process regulated depending on the optically determined melting temperature or at the end of the process Fusion of the ampoule skewers are pivoted into the inoperative position. 37. The method according to claim 3, characterized in that the ampoules for knocking off the spit, Cleaning, drying, if necessary gas pre-filling and filling individually or in groups clamped on a carrier that can be rotated step by step around a horizontal axis and successively in the individual Working positions are brought. 38. The method according to claim 1, characterized in that that the ampoules are only inserted with their skewers into carriers with clamp mounts and by moving them to the individual workplaces and into the correct working position to be brought. 39. The method according to claim 38, characterized in that each ampoule with its Skewer is clamped centrally in a rotational body-like carrier and you through it Rotation one rotation around its longitudinal axis is granted. 40. The method according to claim 39, characterized in that at least the scoring or also other operations in the ampoule position with the skewer pointing downwards be performed. 41. Machine for performing the method according to one of the preceding claims, characterized characterized that for the ampoule carriers (1, 51, 104 to 106, 190) with the same bender, processing-friendly storage of the Ampoule skewers and means (14, 52, 1.11, -112, 194, 195) for continuously conveying the carriers or the ampoules on the carriers from one job to another and (F, /, M, 56, 68, 75, 120 to 122 , 180) are provided for movement into the respective working position. 42. Machine according to claim 41, characterized in that that the carrier for the ampoules consists essentially of three parallel rails (2, 3, 4 or 104, 105, 106), of which two with notches (5, 6) or forks (4 and 3 or 104 and 105) and for Support the ampoule skewer and the ampoule body, while the third (2nd or 106) is intended as a support for the bottom of the ampoule. 43. Machine according to claim 42, characterized in that that serving as a carrier for the ampoules rails (2, 3, 4) as frame-like Support frames (1, 51) designed for groups of ampoules and means for guiding and moving the support frames from job to job is provided are. 44. Machine according to claim 43, characterized in that guide rails (14, 52) are used as guide means, of which individual sections can be pivoted (F, T, M, 56, 75) with the support frames (r, 51) located on them. or displaceable (5, 54, 67) are arranged. 45. Machine according to claim 44, 'characterized in that the movable guide rail abscimitte on a movable support body, such as. B. a rotating body (F, J, M) are arranged. 46. Machine according to claim 42, characterized in that that serving as a carrier for the ampoules rails. (104, 105, 106) stationary arranged and between them means for lifting and advancing the ampoules in other support points for the fixed ampoule support rails (104, 105, 106) provided are. 47. Machine according to claim 46, characterized in that as a means for lifting and Moving the ampoules further with conveyor rails provided with support points (in, 112), conveyor fork bodies (159) or '. The like. Can be used, for example by curve, crank (107, 108) or cross slide drives. 48. Machine according to claim 47, characterized in that the mounting rails (122) for the ampoule skewers with their carriers (120) lying on the ampoule bottom side Support bracket (123) are connected, which outside the range of motion of the ampoules and of their means of transport. 49. Machine according to claim 48, characterized in that that the carrier (104, 122) and conveyor rail (112) for the ampoule skewers in Longitudinal direction of the ampoules and the carrier (105,121) and conveyor rail (111) for the ampoule bodies are arranged transversely to these adjustable. 50. Machine according to claim 43, characterized in that the frame-like support frames (1, 51) set up adjustable for different ampoule lengths and strengths are. 51. Machine according to claim 50, characterized in that that the connecting struts (7) of the ampoule support frames (1) running transversely to the conveying direction are subdivided and the associated ones Parts can be adjusted relative to one another in such a way that, when they are adjusted, the skewer support rail (4) in the longitudinal direction of the ampoule and the ampoule body support rail (3) is adjusted transversely thereto. 52. Machine according to claim 42 or 43, characterized in that movable, elastic pressure plates (59, 70, j6, 128, 137) are arranged and provided with means with their Help them to press the ampoules against their support rails when changing position and lift them off again when the ampoules are conveyed. 'go 53. Machine according to claim 43, characterized in that at the work stations Ampoules on which they assume a position deviating from the normal position, Clip-on brackets (9) are used, which hold the ampoules against their support frames (1) Press and hold it while moving through the relevant jobs. 54. Machine according to claim 42 or 43, characterized in that in their Support rails (104, 105) or support frames (1) dormant ampoules means, such as. B. rotating friction rollers (15, 153), friction belts dreary Like. To generate a rotary movement for the ampoules are provided around their longitudinal center line and in the area of their skewers or a plurality of cutting members (16, 118) are resiliently arranged so that the skewers at the desired To be scratched. 55. Machine according to claim 54, characterized in that the cutting element (16) Guides (20) for the ampoule skewer are connected, 56. Machine according to claim 54 or 55, characterized in that following the work station for scoring the ampoule skewers, a movable section of the conveyor track is switched on, on which a turning device (F, 120, 180) and for the ampoules with their support rails or support frames Below .the guideway stop means (21, 131) are arranged for the abutting spit ends, at which they are brought to break off at the scoring point. 57. Machine according to claim 56, characterized in that the turning device (F, 120, 18o) several evenly over their circumference distributed support rails (121, 122) for the Has ampoules or guide track sections (14) for the support frames. 58. Machine according to claim 56, characterized in that on the turning device in Direction of rotation behind the ampoule skewer below the scoring point a flexible support (64, 129) is attached as a means of interception for the breakaway shock. 59. Machine according to claim 52, characterized in that that at the work site for scoring and knocking off the ampoule skewers a longer than an ampoule rack (1) is made, Guide track section (56) pivotable about an axis of rotation (57) and resiliently held in the normal position and one with Brackets (58) pivotable about the same axis of rotation (57) and longitudinally displaceable on this Pressure plate (59) for an ampoule support frame, below the pivotable guide track section (56) a scoring device (61) and in the return movement area of the ampoule carrier and its pressure plate (59) a stationary stop (63) for knocking off the scored ampoule ends are. 60. Machine according to claim 41, characterized in that that at the cleaning point for the ampoules brought down with their skewers or at an angle opposite theirs Upwardly directed hollow needles (23, 182) with feed devices for cleaning agents are arranged, which with means for their introduction into the ampoules and Control means for the injection of the cleaning agent are equipped. 61. Machine according to claim 41, characterized in that that at the cleaning point for the ampoules opposite their skewers evenly around an intermittently rotatable hollow shaft distributed rows of hollow needles (69) are arranged, which over the hollow shaft and its with several bores provided cock plug with feed devices for different Cleaning and drying agents are in connection and with the at one point over the Rows of hollow needles, together with their support frames, create a cycle around the ampoules Execute hollow shaft. 62. Machine according to claim 41, characterized in that that at the transition point from the job for cleaning and drying A rotatable turning device for the work station for filling the ampoules (/) is arranged, which the ampoules or the ampoule support frames from their cleaning position with the skewer down into the filling position move up with skewer. 63. Machine according to claim 41, characterized in that that at the filling point for the ampoules opposite their skewers filling needles (28, 78, 148, 149, 185) are arranged, which with means for their introduction into the ampoules and for controlling the filling mechanism are equipped. 64. Machine according to claim 63, characterized in that at or in front of the filling point a turning or swiveling device (/, 75, 132) for the ampoules or their support frames is provided, which the ampoules after their clamping by a pressure plate their normal position or another working position brings into the filling position and after Returns the filling process to the normal position at or after the filling point (M). 65. Machine according to claim 63, characterized in that that resilient buttons (79, 142, 143) are used as controls, the are preferably attached to the pressure plate for the ampoules and from the ampoule skewers to be influenced. 66. Machine according to claim 41, characterized in that that at the job for the melting of the ampoule skewers above or below the on the support frames or rails resting ampoules means (friction rollers 29, 153, friction bands 80 or the like) for Generation of a rotary movement of the ampoules provided and in the area of the ampoule skewers one or more melting flames (30, 81/154) are arranged so that they the rotating Melt the ends of the spit. 67. Machine according to claim 66, characterized in that that when attaching a melting flame for each ampoule skewer of an ampoule group, the melting flames of Manually or automatically depending on the conveying movement of the ampoules after completion of the melting process can be swiveled or throttled into the inoperative position are trained. 68. Machine according to claim 41, characterized in that that at the work site for printing the ampoules a movably arranged and provided with coloring agents Printing or transfer printing plate (37, 82, 157) and means for moving the ampoules are provided which the ampoules in the area of the "» Roll off the printing or transfer printing plate. 69. Machine according to claim 68, characterized in that the means for rolling Ampoules on the printing or transfer printing plate for each ampoule a pair of resilient on one common carrier (33, 83, 159) mounted forks (31, 32, 84/85) or notches (159) and a locomotion mechanism is provided for the common carrier, with the With the help of each ampoule body grasped by a pair of forks, lifted out of its storage notches, in the area of the printing or transfer printing plate intended for him with even Pressure rolled and in the same notches of his carried along by the carrier Support frame (1, 51) or in other notches of its fixed bearing rails (104, 105) is deposited. 70. Machine according to claim 69, characterized in that for the movement of the ge common carrier of the resilient forks is a crank (107), curve or cross slide (34 > 36) drive is provided. 71. Machine according to claim 69 or 70, characterized characterized in that the common carrier (33, 83) is only for every second ampoule the ampoule group with a pair of resilient forks (31, 32, 84, 85) and with a controller is equipped, through which he the two halves of the ampoule group in two steps rolls off one after the other on the printing or transfer printing plate. 72. Machine according to one of claims 68 to 71, characterized in that following the printing point under the ampoule web (R, S, k, I) heat sources (e.g. small flames 160 or electrical heating devices) for drying or burning in of the imprint are provided. 73 "Machine for performing the method according to claim 31, characterized in that that the device, which the ampoules through a sterilization chamber or a sterilization bath leads, consists of an endless conveyor belt or the like provided with rows of holes, in its holes after finishing the ampoule processing the ampoules with the help be introduced by turning organs with the spit pointing downwards. 74. Machine according to claim 31, characterized in that that for the support frames with the finished ampoules on one through a sterilization chamber leading endless conveyor means (55) attached holders (89) are provided which are shaped so that they hold the ampoules protect in every position against falling out of their support frames, but those on the ampoule bodies Do not touch the attached labels. 75. Machine according to one of claims 73 or 74, characterized in that in the Sterilizer carriers are provided which hold the ampoules permanently or temporarily hold with the skewer down. 76. Machine according to one of claims 41 to 75, characterized in that "that a lifting plate (90) which is expediently provided with grooves corresponding to the ampoule storage grooves is inclined in such a way that the ampoules over the bottom rail (2) when it is lifted or when an ampoule support frame is pushed back against it. are lifted or pulled out and slide under their own weight on a slide (91) arranged below and in front of them, which is also expediently provided with grooves for the individual ampoules _r the distance between them is reduced so that the ampoules are passed directly into the sales package can. 7Y. Machine according to claim 44, characterized in that a horizontally mounted rotating body (180) with rail sections (121, 122) evenly distributed over its circumference is provided for the storage of the ampoules or their support frames for the operations with the ampoule position deviating from the normal position Ampoules are directed with their skewers outward, and that on the various switching positions of the rotating body with respect to the ampoule skewers with the exception of a switching position intended for the supply and removal of the ampoules hollow needles (182 to 185) with the associated introduction and control devices for the supply line Cleaning and drying agents and the contents are arranged. 78. Machine according to claim 41, characterized by a movable ampoule carrier with clamping devices for the Ampoule skewer, which brings the ampoules to the individual workplaces and puts them in the respective work situation. 79. Machine according to claim 78, characterized in that one for each ampoule Rotary body-like carrier (190) is provided, in the middle of which the ampoule skewer enters is clamped. 80. Machine according to claim 78 or 79, characterized in that the clamping devices in the beams of angled or semicircular stops (192) and opposing ones resilient pressure members (193) exist. 81. Machine according to claim 80, characterized in that that the rigid stop (192) is arranged to be radially adjustable, so that ampoule skewers different strengths can be clamped in a central position in the same carrier. 82. Machine according to claim 79, characterized in that that the ampoule carriers are rotatably arranged, so that by their rotation, the. ampoules clamped in it their longitudinal center line can be rotated. 83. Machine according to one of claims 41 to 46, characterized in that on a rail track (14, aa to dd, 52 to 54, 104 to 106, 194, 195) for the step-by-step conveyance of the ampoules or their support frames from work to work with constant skewer storage facilities for scoring ( 15, 16, 61, 113 to 118), open (I ⁷ with 21, 57 to 60 with 63 and 64, 120 with 129 and 131, 180 with 131), fill (28, 78, 148, 149, 185) and Closing (29 with 30, 80 with 81, 153 with 154) of ampoules and movable track sections (F, /, M; 56, 75; 120 to 122, 132 to 134; 195) and clamping devices (9, 59, 76, 128, 137, 138) are provided for transferring the ampoules or their support frames into the working positions required for the work processes mentioned. 84. Machine according to claim 83, characterized in that before the device for Filling the ampoules Facilities for cleaning, drying (23 to 25, 66 to 73, 182 to 184) and, if necessary, are arranged for sterilizing the empty ampoules. 85. Machine according to claim 83 or 84, characterized in that a device for printing (31 to 37, 82 to 86, 157 to 159) of the ampoules is arranged at one point on the rail track, to which a device for drying or Burn-in of the imprint (R, S; 160) then follows. 86. Machine according to one of claims 83 to 85, characterized in that the Rail track leads through a sterilization device or is connected to such a device (86) is. 87. Machine according to one of claims 83 to 86, characterized in that on the Railroad a device for generating a voltage in the ampoule skewer on the future opening point is arranged, which consists of a device for heating the Ampoule neck and a cooling ring that touches the heated area. 88. Machine according to one of claims 83 to 87, characterized in that all Facilities that are required for the treatment of the delivered empty ampoule up to the sales package, one after the other are arranged on the railroad. 89. Machine according to one of claims 83 to 88, characterized in that on the Rail track also arranged a device for the manufacture of ampoules from glass tubes or is connected to it. 90. The method according to claim 1, characterized in that that at the individual workplaces the promotion of the ampoules or their support frames and the operation of the processing equipment be carried out by hand at the individual workplaces by persons deployed at them, whereby the The lead time at each job corresponds to the working time of that job, which takes the longest time for the ampoules to pass through. For this purpose 2 sheets of drawings 509 550 9.55