DE911535C - Process for the preparation of solutions of tyrothricin - Google Patents

Process for the preparation of solutions of tyrothricin

Info

Publication number
DE911535C
DE911535C DEC6035A DEC0006035A DE911535C DE 911535 C DE911535 C DE 911535C DE C6035 A DEC6035 A DE C6035A DE C0006035 A DEC0006035 A DE C0006035A DE 911535 C DE911535 C DE 911535C
Authority
DE
Germany
Prior art keywords
tyrothricin
solutions
preparation
acids
carbonamide
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
DEC6035A
Other languages
German (de)
Inventor
Dipl-Chem Erich Jansen
Dipl-Chem Dr Heinrich Mueckter
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Gruenenthal GmbH
Original Assignee
Gruenenthal GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Gruenenthal GmbH filed Critical Gruenenthal GmbH
Priority to DEC6035A priority Critical patent/DE911535C/en
Application granted granted Critical
Publication of DE911535C publication Critical patent/DE911535C/en
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Molecular Biology (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)

Description

Verfahren zur Herstellung von Lösungen des Tyrothricins Gegenstand des Patents wo6 983 ist ein Verfahren zur Herstellung von Lösungen des Tyrothricins in pflanzlichen t)len. Die Erfindung des Hauptpatents beruht darauf, daß als Lösungsvermittler Säuren der aliphatischen Reihe, die durch eine oder mehrere Oxygruppen substituiert sind und vorzugsweise eine Kettenlänge von 8 bis I8 C-Atomen besitzen, oder Salze von solchen Säuren verwendet werden.Process for the preparation of solutions of tyrothricin object of patent WO6,983 is a process for the preparation of solutions of tyrothricin in vegetable oils. The invention of the main patent is based on the fact that as a solubilizer Acids of the aliphatic series which are substituted by one or more oxy groups are and preferably have a chain length of 8 to 18 carbon atoms, or salts of such acids can be used.

Bei der weiteren Bearbeitung der Erfindung des Hauptpatents wurde nunmehr gefunden, daß als Lösungsvermittler nicht nur die im Hauptpatent erwähnten Säuren und deren Salze, sondern auch die von Fettsäuren sich ableitenden Carbonamide sowie deren N-Substitutionsprodukte verwendet werden können. In the further processing of the invention of the main patent was now found that not only those mentioned in the main patent as solubilizers Acids and their salts, but also the carbonamides derived from fatty acids as well as their N-substitution products can be used.

Beispiel Eine Lösung von 62,5 mg Tyrothricin in I ccm wasserfreiem Alkohol wird in 2,5 g N-Methylacetamid gegeben. In die klare Lösung wird langsam Rizinusöl bis zu einem Gesamtgewicht von loo g eingerührt, wobei man eine völlig klare Lösung erhält. Example A solution of 62.5 mg of tyrothricin in 1 cc of anhydrous Alcohol is added to 2.5 g of N-methylacetamide. In the clear solution will be slow Castor oil is stirred in up to a total weight of loo g, whereby one completely receives clear solution.

Claims (1)

PATENTANSPRUCH: Verfahren zur Herstellung von Lösungen des Tyrothricins gemäß Patent 906 983, dadurch gekennzeichnet, daß das Tyrothricin in einem pflanzlichen MI mit Hilfe eines von einer Fettsäure abgeleiteten Carbonamides oder eines N-Substitutionsproduktes eines solchen Carbonamides gelöst wird. PATENT CLAIM: Process for the preparation of solutions of tyrothricin according to patent 906 983, characterized in that the tyrothricin in a vegetable MI using a carbonamide derived from a fatty acid or an N-substitution product such a carbonamide is dissolved.
DEC6035A 1952-06-29 1952-06-29 Process for the preparation of solutions of tyrothricin Expired DE911535C (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
DEC6035A DE911535C (en) 1952-06-29 1952-06-29 Process for the preparation of solutions of tyrothricin

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DEC6035A DE911535C (en) 1952-06-29 1952-06-29 Process for the preparation of solutions of tyrothricin

Publications (1)

Publication Number Publication Date
DE911535C true DE911535C (en) 1954-05-17

Family

ID=7013813

Family Applications (1)

Application Number Title Priority Date Filing Date
DEC6035A Expired DE911535C (en) 1952-06-29 1952-06-29 Process for the preparation of solutions of tyrothricin

Country Status (1)

Country Link
DE (1) DE911535C (en)

Similar Documents

Publication Publication Date Title
DE717968C (en) Additive to lubricants
DE1418860A1 (en) Process for the production of anionically surface-active isethionic acid esters
DE911535C (en) Process for the preparation of solutions of tyrothricin
DE850051C (en) Process for producing high pressure resistant, consistent lubricating greases
DE638814C (en) Process for the production of plastics by reacting polyvinyl alcohols with aldehydes
DE2424712B2 (en) Citric acid esters, their manufacture and use
EP0259768A3 (en) Lubricant composition for the processing of rigid pvc
DE943380C (en) Process for improving unsaturated polyester resins
DE940383C (en) Herbicides
DE528741C (en) Process for the preparation of a water-soluble polymerisation product
DE759064C (en) Method of accelerating yeast fermentation
DE560916C (en) Soap-like products
DE1114177B (en) Process for the production of lactic acid
DE630526C (en) Process for the preparation of derivatives of higher alcohols
DE725923C (en) Process for the production of concentrated solutions of organic medicinal products which are poorly soluble or insoluble in water
DE845515C (en) Process for the preparation of quaternary ammonium compounds
DE551403C (en) Process for the production of emulsions
DE977755C (en) Process for the production of stable polyvinyl nitrate
DE642518C (en) Process for the production of higher aliphatic alcohols
DE645882C (en) Process for the preparation of nitrogenous compounds
DE748543C (en) Process for the preparation of quaternary ammonium compounds
DE444064C (en) Process for the preparation of water-soluble double compounds of digitoglycotannoids, the totality of digitalis glycosides in their natural form
DE681225C (en) Process for the production of mixtures from soaps and higher molecular weight dihydric alcohols
DE688047C (en) Process for the production of stable aqueous, therapeutically usable solutions of the polyoxyalkylisoalloxazines
DE893648C (en) Solvent or solubilizer for salicylic acid