DE69935219D1 - Klonierung und identifizierung des motilin-rezeptors - Google Patents

Klonierung und identifizierung des motilin-rezeptors

Info

Publication number
DE69935219D1
DE69935219D1 DE69935219T DE69935219T DE69935219D1 DE 69935219 D1 DE69935219 D1 DE 69935219D1 DE 69935219 T DE69935219 T DE 69935219T DE 69935219 T DE69935219 T DE 69935219T DE 69935219 D1 DE69935219 D1 DE 69935219D1
Authority
DE
Germany
Prior art keywords
motilin receptor
identification
cloning
receptor
motilin
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69935219T
Other languages
English (en)
Inventor
Scott D Feighner
Arthur A Patchett
Carina Tan
Karen Mckee
Douglas Macneil
Andrew D Howard
Sheng-Shung Pong
Roy G Smith
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck and Co Inc
Original Assignee
Merck and Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck and Co Inc filed Critical Merck and Co Inc
Application granted granted Critical
Publication of DE69935219D1 publication Critical patent/DE69935219D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
DE69935219T 1998-06-12 1999-06-08 Klonierung und identifizierung des motilin-rezeptors Expired - Lifetime DE69935219D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US8909898P 1998-06-12 1998-06-12
PCT/US1999/012773 WO1999064436A1 (en) 1998-06-12 1999-06-08 Cloning and identification of the motilin receptor

Publications (1)

Publication Number Publication Date
DE69935219D1 true DE69935219D1 (de) 2007-04-05

Family

ID=22215674

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69935219T Expired - Lifetime DE69935219D1 (de) 1998-06-12 1999-06-08 Klonierung und identifizierung des motilin-rezeptors

Country Status (6)

Country Link
EP (1) EP1086117B1 (de)
JP (1) JP2002517507A (de)
AT (1) ATE354582T1 (de)
CA (1) CA2330251A1 (de)
DE (1) DE69935219D1 (de)
WO (1) WO1999064436A1 (de)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030229216A1 (en) 1998-10-13 2003-12-11 Ruoping Chen Constitutively activated human G protein coupled receptors
US7816492B2 (en) 1998-11-20 2010-10-19 Arena Pharmaceuticals, Inc. Human G protein-coupled receptors
US20030017528A1 (en) 1998-11-20 2003-01-23 Ruoping Chen Human orphan G protein-coupled receptors
USRE42190E1 (en) 1998-11-20 2011-03-01 Arena Pharmaceuticals, Inc. Method of identifying a compound for inhibiting or stimulating human G protein-coupled receptors
EP1228096A4 (de) * 1999-10-29 2003-07-23 Merck & Co Inc Hund- und kaninchen-orthologedes motilinrezeptors
WO2001064836A2 (en) * 2000-03-01 2001-09-07 Smithkline Beecham Corporation Cloning of a gpr38 variant
US20050009204A1 (en) * 2003-07-11 2005-01-13 Ye Fang Multiplexed binding assays for receptor arrays
CN1708309A (zh) * 2002-10-25 2005-12-14 中外制药株式会社 排便功能障碍的治疗和/或预防剂
JP4928261B2 (ja) 2003-06-18 2012-05-09 トランザイム・ファーマ・インコーポレイテッド モチリン受容体の大環状拮抗薬
PE20070180A1 (es) * 2005-07-26 2007-04-25 Glaxo Group Ltd Compuestos de bencilpiperazina como agonistas del receptor gpr38
EP2431380A3 (de) 2006-09-11 2013-07-03 Tranzyme Pharma, Inc. Makrozyklischer Antagonist des Motilinrezeptors zur Behandlung von Magen-Darm-Motilitätsstörungen

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5712253A (en) * 1996-06-18 1998-01-27 Abbott Laboratories Macrocyclic 13-membered ring derivatives of erythromycins A and B

Also Published As

Publication number Publication date
EP1086117A4 (de) 2005-05-04
ATE354582T1 (de) 2007-03-15
EP1086117A1 (de) 2001-03-28
EP1086117B1 (de) 2007-02-21
WO1999064436A1 (en) 1999-12-16
JP2002517507A (ja) 2002-06-18
CA2330251A1 (en) 1999-12-16

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Legal Events

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