DE69934482T2 - Nachweis, abbildung und kennzeichnung von brustumoren - Google Patents
Nachweis, abbildung und kennzeichnung von brustumoren Download PDFInfo
- Publication number
- DE69934482T2 DE69934482T2 DE69934482T DE69934482T DE69934482T2 DE 69934482 T2 DE69934482 T2 DE 69934482T2 DE 69934482 T DE69934482 T DE 69934482T DE 69934482 T DE69934482 T DE 69934482T DE 69934482 T2 DE69934482 T2 DE 69934482T2
- Authority
- DE
- Germany
- Prior art keywords
- optical
- light
- mentioned
- optical system
- detector
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 210000000481 breast Anatomy 0.000 title claims description 149
- 230000003287 optical effect Effects 0.000 claims description 211
- 238000001514 detection method Methods 0.000 claims description 73
- 239000008280 blood Substances 0.000 claims description 69
- 210000004369 blood Anatomy 0.000 claims description 69
- 230000005855 radiation Effects 0.000 claims description 63
- 238000000034 method Methods 0.000 claims description 35
- 238000006392 deoxygenation reaction Methods 0.000 claims description 33
- 238000013508 migration Methods 0.000 claims description 23
- 230000005012 migration Effects 0.000 claims description 23
- 238000004422 calculation algorithm Methods 0.000 claims description 22
- 238000010521 absorption reaction Methods 0.000 claims description 20
- 210000000038 chest Anatomy 0.000 claims description 20
- 238000006213 oxygenation reaction Methods 0.000 claims description 17
- 108010054147 Hemoglobins Proteins 0.000 claims description 16
- 102000001554 Hemoglobins Human genes 0.000 claims description 16
- 230000002159 abnormal effect Effects 0.000 claims description 11
- 239000000049 pigment Substances 0.000 claims description 10
- 230000010363 phase shift Effects 0.000 claims description 9
- 238000003325 tomography Methods 0.000 claims description 8
- 239000002872 contrast media Substances 0.000 claims description 7
- 238000012545 processing Methods 0.000 claims description 7
- 230000015572 biosynthetic process Effects 0.000 claims description 6
- 239000004744 fabric Substances 0.000 claims description 6
- 230000035945 sensitivity Effects 0.000 claims description 6
- 230000004888 barrier function Effects 0.000 claims description 5
- 230000008859 change Effects 0.000 claims description 5
- 238000001727 in vivo Methods 0.000 claims description 5
- 239000000463 material Substances 0.000 claims description 4
- 239000013307 optical fiber Substances 0.000 claims description 3
- 238000013139 quantization Methods 0.000 claims description 2
- 238000000149 argon plasma sintering Methods 0.000 claims 2
- 230000001276 controlling effect Effects 0.000 claims 1
- 230000002596 correlated effect Effects 0.000 claims 1
- 230000000875 corresponding effect Effects 0.000 claims 1
- 230000008878 coupling Effects 0.000 claims 1
- 238000010168 coupling process Methods 0.000 claims 1
- 238000005859 coupling reaction Methods 0.000 claims 1
- 210000001519 tissue Anatomy 0.000 description 149
- 238000003384 imaging method Methods 0.000 description 64
- 206010028980 Neoplasm Diseases 0.000 description 39
- 206010036618 Premenstrual syndrome Diseases 0.000 description 21
- 238000001816 cooling Methods 0.000 description 12
- 201000011510 cancer Diseases 0.000 description 11
- 238000002591 computed tomography Methods 0.000 description 10
- 238000010586 diagram Methods 0.000 description 10
- 230000033115 angiogenesis Effects 0.000 description 9
- 238000009607 mammography Methods 0.000 description 9
- 238000005259 measurement Methods 0.000 description 9
- 239000000523 sample Substances 0.000 description 8
- 210000002445 nipple Anatomy 0.000 description 7
- 238000010606 normalization Methods 0.000 description 7
- 208000026310 Breast neoplasm Diseases 0.000 description 6
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 description 6
- 230000000694 effects Effects 0.000 description 6
- 238000002595 magnetic resonance imaging Methods 0.000 description 6
- 238000012634 optical imaging Methods 0.000 description 6
- 229910052760 oxygen Inorganic materials 0.000 description 6
- 239000001301 oxygen Substances 0.000 description 6
- XUIMIQQOPSSXEZ-UHFFFAOYSA-N Silicon Chemical compound [Si] XUIMIQQOPSSXEZ-UHFFFAOYSA-N 0.000 description 5
- 230000008569 process Effects 0.000 description 5
- 229910052710 silicon Inorganic materials 0.000 description 5
- 239000010703 silicon Substances 0.000 description 5
- 238000002604 ultrasonography Methods 0.000 description 5
- 206010006187 Breast cancer Diseases 0.000 description 4
- 230000008901 benefit Effects 0.000 description 4
- 230000005540 biological transmission Effects 0.000 description 4
- 238000009792 diffusion process Methods 0.000 description 4
- 238000007689 inspection Methods 0.000 description 4
- 230000005865 ionizing radiation Effects 0.000 description 4
- 238000013507 mapping Methods 0.000 description 4
- 230000002503 metabolic effect Effects 0.000 description 4
- 238000012360 testing method Methods 0.000 description 4
- 238000013334 tissue model Methods 0.000 description 4
- 206010020674 Hypermetabolism Diseases 0.000 description 3
- 230000002491 angiogenic effect Effects 0.000 description 3
- 239000003990 capacitor Substances 0.000 description 3
- 238000012512 characterization method Methods 0.000 description 3
- 201000010099 disease Diseases 0.000 description 3
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 3
- 238000011156 evaluation Methods 0.000 description 3
- 238000002599 functional magnetic resonance imaging Methods 0.000 description 3
- 230000004807 localization Effects 0.000 description 3
- 230000001575 pathological effect Effects 0.000 description 3
- 238000000926 separation method Methods 0.000 description 3
- 238000004611 spectroscopical analysis Methods 0.000 description 3
- 208000032843 Hemorrhage Diseases 0.000 description 2
- 206010041662 Splinter Diseases 0.000 description 2
- 230000002745 absorbent Effects 0.000 description 2
- 239000002250 absorbent Substances 0.000 description 2
- 210000000577 adipose tissue Anatomy 0.000 description 2
- 230000002238 attenuated effect Effects 0.000 description 2
- 230000002146 bilateral effect Effects 0.000 description 2
- 210000004556 brain Anatomy 0.000 description 2
- 210000004027 cell Anatomy 0.000 description 2
- 239000000470 constituent Substances 0.000 description 2
- 230000001419 dependent effect Effects 0.000 description 2
- 239000006185 dispersion Substances 0.000 description 2
- 230000005670 electromagnetic radiation Effects 0.000 description 2
- 238000001704 evaporation Methods 0.000 description 2
- 230000008020 evaporation Effects 0.000 description 2
- 238000007387 excisional biopsy Methods 0.000 description 2
- 238000001914 filtration Methods 0.000 description 2
- 230000006870 function Effects 0.000 description 2
- 230000036541 health Effects 0.000 description 2
- 238000011503 in vivo imaging Methods 0.000 description 2
- MOFVSTNWEDAEEK-UHFFFAOYSA-M indocyanine green Chemical compound [Na+].[O-]S(=O)(=O)CCCCN1C2=CC=C3C=CC=CC3=C2C(C)(C)C1=CC=CC=CC=CC1=[N+](CCCCS([O-])(=O)=O)C2=CC=C(C=CC=C3)C3=C2C1(C)C MOFVSTNWEDAEEK-UHFFFAOYSA-M 0.000 description 2
- 239000004615 ingredient Substances 0.000 description 2
- 239000007788 liquid Substances 0.000 description 2
- 230000004060 metabolic process Effects 0.000 description 2
- 238000013188 needle biopsy Methods 0.000 description 2
- 210000000056 organ Anatomy 0.000 description 2
- 230000007310 pathophysiology Effects 0.000 description 2
- 230000035515 penetration Effects 0.000 description 2
- 238000011002 quantification Methods 0.000 description 2
- 230000001960 triggered effect Effects 0.000 description 2
- 210000004881 tumor cell Anatomy 0.000 description 2
- WFKWXMTUELFFGS-UHFFFAOYSA-N tungsten Chemical compound [W] WFKWXMTUELFFGS-UHFFFAOYSA-N 0.000 description 2
- 229910052721 tungsten Inorganic materials 0.000 description 2
- 239000010937 tungsten Substances 0.000 description 2
- INGWEZCOABYORO-UHFFFAOYSA-N 2-(furan-2-yl)-7-methyl-1h-1,8-naphthyridin-4-one Chemical compound N=1C2=NC(C)=CC=C2C(O)=CC=1C1=CC=CO1 INGWEZCOABYORO-UHFFFAOYSA-N 0.000 description 1
- 206010001233 Adenoma benign Diseases 0.000 description 1
- 238000012935 Averaging Methods 0.000 description 1
- 206010006272 Breast mass Diseases 0.000 description 1
- 208000007659 Fibroadenoma Diseases 0.000 description 1
- 229910052688 Gadolinium Inorganic materials 0.000 description 1
- 241000282412 Homo Species 0.000 description 1
- 206010021143 Hypoxia Diseases 0.000 description 1
- 206010027476 Metastases Diseases 0.000 description 1
- 241001465754 Metazoa Species 0.000 description 1
- 108010064719 Oxyhemoglobins Proteins 0.000 description 1
- 230000005856 abnormality Effects 0.000 description 1
- 239000006096 absorbing agent Substances 0.000 description 1
- 239000011358 absorbing material Substances 0.000 description 1
- 238000009825 accumulation Methods 0.000 description 1
- 239000002870 angiogenesis inducing agent Substances 0.000 description 1
- 230000001640 apoptogenic effect Effects 0.000 description 1
- 230000008033 biological extinction Effects 0.000 description 1
- 238000001574 biopsy Methods 0.000 description 1
- 238000009534 blood test Methods 0.000 description 1
- 210000004204 blood vessel Anatomy 0.000 description 1
- 210000005013 brain tissue Anatomy 0.000 description 1
- 201000003149 breast fibroadenoma Diseases 0.000 description 1
- 238000004364 calculation method Methods 0.000 description 1
- 230000000711 cancerogenic effect Effects 0.000 description 1
- 231100000315 carcinogenic Toxicity 0.000 description 1
- 230000004663 cell proliferation Effects 0.000 description 1
- 230000000052 comparative effect Effects 0.000 description 1
- 230000000295 complement effect Effects 0.000 description 1
- 150000001875 compounds Chemical class 0.000 description 1
- 238000004590 computer program Methods 0.000 description 1
- 238000010276 construction Methods 0.000 description 1
- 210000004246 corpus luteum Anatomy 0.000 description 1
- 238000012937 correction Methods 0.000 description 1
- 238000013016 damping Methods 0.000 description 1
- 238000013481 data capture Methods 0.000 description 1
- 108010002255 deoxyhemoglobin Proteins 0.000 description 1
- 238000002059 diagnostic imaging Methods 0.000 description 1
- 238000006073 displacement reaction Methods 0.000 description 1
- 230000009977 dual effect Effects 0.000 description 1
- 210000000624 ear auricle Anatomy 0.000 description 1
- 230000013020 embryo development Effects 0.000 description 1
- 210000004696 endometrium Anatomy 0.000 description 1
- 210000002889 endothelial cell Anatomy 0.000 description 1
- 230000008175 fetal development Effects 0.000 description 1
- 239000000835 fiber Substances 0.000 description 1
- 239000012530 fluid Substances 0.000 description 1
- 239000006261 foam material Substances 0.000 description 1
- 229920001821 foam rubber Polymers 0.000 description 1
- UIWYJDYFSGRHKR-UHFFFAOYSA-N gadolinium atom Chemical compound [Gd] UIWYJDYFSGRHKR-UHFFFAOYSA-N 0.000 description 1
- 230000005251 gamma ray Effects 0.000 description 1
- 238000012333 histopathological diagnosis Methods 0.000 description 1
- 230000003166 hypermetabolic effect Effects 0.000 description 1
- 230000007954 hypoxia Effects 0.000 description 1
- 229960004657 indocyanine green Drugs 0.000 description 1
- 230000000977 initiatory effect Effects 0.000 description 1
- 230000010354 integration Effects 0.000 description 1
- 238000011835 investigation Methods 0.000 description 1
- 238000002690 local anesthesia Methods 0.000 description 1
- 210000004324 lymphatic system Anatomy 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 230000001394 metastastic effect Effects 0.000 description 1
- 206010061289 metastatic neoplasm Diseases 0.000 description 1
- 210000004088 microvessel Anatomy 0.000 description 1
- 230000003278 mimic effect Effects 0.000 description 1
- 230000001338 necrotic effect Effects 0.000 description 1
- 230000008557 oxygen metabolism Effects 0.000 description 1
- 230000007170 pathology Effects 0.000 description 1
- 210000002976 pectoralis muscle Anatomy 0.000 description 1
- 230000002085 persistent effect Effects 0.000 description 1
- 230000004962 physiological condition Effects 0.000 description 1
- 230000035479 physiological effects, processes and functions Effects 0.000 description 1
- 210000002826 placenta Anatomy 0.000 description 1
- 239000004033 plastic Substances 0.000 description 1
- 230000035755 proliferation Effects 0.000 description 1
- 230000002035 prolonged effect Effects 0.000 description 1
- 238000011158 quantitative evaluation Methods 0.000 description 1
- 238000012552 review Methods 0.000 description 1
- 238000007665 sagging Methods 0.000 description 1
- 238000012216 screening Methods 0.000 description 1
- 210000004872 soft tissue Anatomy 0.000 description 1
- 239000002904 solvent Substances 0.000 description 1
- 230000004083 survival effect Effects 0.000 description 1
- 230000001360 synchronised effect Effects 0.000 description 1
- 230000002277 temperature effect Effects 0.000 description 1
- 230000001225 therapeutic effect Effects 0.000 description 1
- 230000007704 transition Effects 0.000 description 1
- 230000004614 tumor growth Effects 0.000 description 1
- 230000002792 vascular Effects 0.000 description 1
- 230000004862 vasculogenesis Effects 0.000 description 1
- 230000029663 wound healing Effects 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/0059—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence
- A61B5/0082—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence adapted for particular medical purposes
- A61B5/0091—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence adapted for particular medical purposes for mammography
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/0059—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence
- A61B5/0073—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence by tomography, i.e. reconstruction of 3D images from 2D projections
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue
- A61B5/1455—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue using optical sensors, e.g. spectral photometrical oximeters
- A61B5/14551—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue using optical sensors, e.g. spectral photometrical oximeters for measuring blood gases
- A61B5/14552—Details of sensors specially adapted therefor
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/43—Detecting, measuring or recording for evaluating the reproductive systems
- A61B5/4306—Detecting, measuring or recording for evaluating the reproductive systems for evaluating the female reproductive systems, e.g. gynaecological evaluations
- A61B5/4312—Breast evaluation or disorder diagnosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B2562/00—Details of sensors; Constructional details of sensor housings or probes; Accessories for sensors
- A61B2562/02—Details of sensors specially adapted for in-vivo measurements
- A61B2562/0233—Special features of optical sensors or probes classified in A61B5/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B2562/00—Details of sensors; Constructional details of sensor housings or probes; Accessories for sensors
- A61B2562/02—Details of sensors specially adapted for in-vivo measurements
- A61B2562/0233—Special features of optical sensors or probes classified in A61B5/00
- A61B2562/0242—Special features of optical sensors or probes classified in A61B5/00 for varying or adjusting the optical path length in the tissue
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B2562/00—Details of sensors; Constructional details of sensor housings or probes; Accessories for sensors
- A61B2562/04—Arrangements of multiple sensors of the same type
- A61B2562/046—Arrangements of multiple sensors of the same type in a matrix array
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Physics & Mathematics (AREA)
- Surgery (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Medical Informatics (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Animal Behavior & Ethology (AREA)
- Pathology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Spectroscopy & Molecular Physics (AREA)
- Optics & Photonics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Radiology & Medical Imaging (AREA)
- Gynecology & Obstetrics (AREA)
- Reproductive Health (AREA)
- Investigating Or Analysing Materials By Optical Means (AREA)
- Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US7450498P | 1998-02-11 | 1998-02-11 | |
| US74504P | 1998-02-11 | ||
| US9801898P | 1998-08-26 | 1998-08-26 | |
| US98018P | 1998-08-26 | ||
| PCT/US1999/002953 WO1999040840A1 (en) | 1998-02-11 | 1999-02-11 | Detection, imaging and characterization of breast tumors |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DE69934482D1 DE69934482D1 (de) | 2007-02-01 |
| DE69934482T2 true DE69934482T2 (de) | 2007-09-27 |
Family
ID=26755735
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE69934482T Expired - Lifetime DE69934482T2 (de) | 1998-02-11 | 1999-02-11 | Nachweis, abbildung und kennzeichnung von brustumoren |
Country Status (6)
| Country | Link |
|---|---|
| US (2) | US7627365B2 (enExample) |
| EP (1) | EP1054618B1 (enExample) |
| JP (2) | JP4733264B2 (enExample) |
| CA (1) | CA2319454C (enExample) |
| DE (1) | DE69934482T2 (enExample) |
| WO (1) | WO1999040840A1 (enExample) |
Families Citing this family (74)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP4733264B2 (ja) * | 1998-02-11 | 2011-07-27 | ノン−インヴェイシヴ テクノロジイ,インク. | 胸部腫瘍の検出、画像形成および特徴表示 |
| CA2319458C (en) * | 1998-02-13 | 2012-04-03 | Non-Invasive Technology, Inc. | Transabdominal examination, monitoring and imaging of tissue |
| US6949081B1 (en) | 1998-08-26 | 2005-09-27 | Non-Invasive Technology, Inc. | Sensing and interactive drug delivery |
| US7840257B2 (en) | 2003-01-04 | 2010-11-23 | Non Invasive Technology, Inc. | Examination of biological tissue using non-contact optical probes |
| NL1012943C2 (nl) | 1999-08-31 | 2001-03-01 | Tno | Detector en beeldvormende inrichting voor het bepalen van concentratieverhoudingen. |
| US7006676B1 (en) | 2000-01-21 | 2006-02-28 | Medical Optical Imaging, Inc. | Method and apparatus for detecting an abnormality within a host medium utilizing frequency-swept modulation diffusion tomography |
| DE10109539A1 (de) * | 2001-02-28 | 2002-09-12 | Siemens Ag | Vorrichtung zur Untersuchung von Gewebe mit Licht |
| JP4781548B2 (ja) * | 2001-03-14 | 2011-09-28 | 浜松ホトニクス株式会社 | 乳がん検出装置 |
| US8078262B2 (en) * | 2001-04-16 | 2011-12-13 | The Johns Hopkins University | Method for imaging and spectroscopy of tumors and determination of the efficacy of anti-tumor drug therapies |
| GB0213836D0 (en) * | 2002-06-14 | 2002-07-24 | Electrode Company The Ltd | Analytical apparatus |
| US7490085B2 (en) * | 2002-12-18 | 2009-02-10 | Ge Medical Systems Global Technology Company, Llc | Computer-assisted data processing system and method incorporating automated learning |
| US20040122719A1 (en) * | 2002-12-18 | 2004-06-24 | Sabol John M. | Medical resource processing system and method utilizing multiple resource type data |
| US20040122703A1 (en) * | 2002-12-19 | 2004-06-24 | Walker Matthew J. | Medical data operating model development system and method |
| DE10332301B4 (de) * | 2003-07-16 | 2009-07-30 | Siemens Ag | Vorrichtung für die medizinische Diagnose |
| EP1776652A2 (en) * | 2004-08-06 | 2007-04-25 | Invivo Corporation | Method and apparatus for positioning a biopsy needle |
| KR100612863B1 (ko) * | 2004-10-11 | 2006-08-14 | 삼성전자주식회사 | 체지방 측정 장치 및 방법 |
| EP2191774A3 (en) * | 2004-12-06 | 2010-06-23 | Cambridge Research & Instrumentation, Inc. | Systems and methods for in-vivo optical imaging and measurement |
| US20060239921A1 (en) * | 2005-04-26 | 2006-10-26 | Novadaq Technologies Inc. | Real time vascular imaging during solid organ transplant |
| US8185176B2 (en) | 2005-04-26 | 2012-05-22 | Novadaq Technologies, Inc. | Method and apparatus for vasculature visualization with applications in neurosurgery and neurology |
| US20070004972A1 (en) * | 2005-06-29 | 2007-01-04 | Johnson & Johnson Consumer Companies, Inc. | Handheld device for determining skin age, proliferation status and photodamage level |
| WO2007016048A2 (en) * | 2005-07-27 | 2007-02-08 | University Of Massachusetts Lowell | Infrared scanner for biological applications |
| CA2618443A1 (en) * | 2005-08-10 | 2007-02-15 | Novadaq Technologies, Inc. | Intra-operative head & neck nerve mapping |
| US20070122344A1 (en) * | 2005-09-02 | 2007-05-31 | University Of Rochester Medical Center Office Of Technology Transfer | Intraoperative determination of nerve location |
| WO2007060602A2 (en) * | 2005-11-23 | 2007-05-31 | Koninklijke Philips Electronics N.V. | A method and device for imaging an interior of a turbid medium |
| CN101404925A (zh) * | 2006-03-17 | 2009-04-08 | 皇家飞利浦电子股份有限公司 | 用于混浊介质成像的设备 |
| KR101041295B1 (ko) * | 2006-03-31 | 2011-06-14 | 가부시키가이샤 시마즈세이사쿠쇼 | 맘모그래피 장치 |
| GB0607270D0 (en) | 2006-04-11 | 2006-05-17 | Univ Nottingham | The pulsing blood supply |
| WO2007149751A2 (en) | 2006-06-22 | 2007-12-27 | Koninklijke Philips Electronics, N.V. | Multi-source encoded x-ray imaging |
| WO2007149971A2 (en) * | 2006-06-22 | 2007-12-27 | General Hospital Corporation | Cancer detection by optical measurement of compression-induced transients |
| GB0613165D0 (en) * | 2006-06-28 | 2006-08-09 | Univ Warwick | Real-time infrared measurement and imaging system |
| WO2008015604A2 (en) * | 2006-07-31 | 2008-02-07 | Koninklijke Philips Electronics N.V. | Measurement with multiplexed detection |
| US20080161744A1 (en) * | 2006-09-07 | 2008-07-03 | University Of Rochester Medical Center | Pre-And Intra-Operative Localization of Penile Sentinel Nodes |
| US20080218727A1 (en) * | 2006-12-22 | 2008-09-11 | Art, Advanced Research Technologies Inc. | Method and apparatus for optical image reconstruction using contour determination |
| US20080177163A1 (en) * | 2007-01-19 | 2008-07-24 | O2 Medtech, Inc. | Volumetric image formation from optical scans of biological tissue with multiple applications including deep brain oxygenation level monitoring |
| DE102007047021B4 (de) * | 2007-10-01 | 2011-07-28 | Siemens AG, 80333 | Anordnung zur Übertragung von Magnetresonanzsignalen |
| WO2009060448A2 (en) * | 2007-11-08 | 2009-05-14 | Inolact Ltd. | Measuring fluid excreted from an organ |
| DE102007057013A1 (de) * | 2007-11-23 | 2009-05-28 | Image Diagnost International Gmbh | Verfahren und Vorrichtung zur Verarbeitung digitaler Mammogramme |
| US8406860B2 (en) | 2008-01-25 | 2013-03-26 | Novadaq Technologies Inc. | Method for evaluating blush in myocardial tissue |
| US10219742B2 (en) | 2008-04-14 | 2019-03-05 | Novadaq Technologies ULC | Locating and analyzing perforator flaps for plastic and reconstructive surgery |
| US8686698B2 (en) * | 2008-04-16 | 2014-04-01 | Enpirion, Inc. | Power converter with controller operable in selected modes of operation |
| WO2009135178A2 (en) | 2008-05-02 | 2009-11-05 | Flower Robert W | Methods for production and use of substance-loaded erythrocytes (s-les) for observation and treatment of microvascular hemodynamics |
| DK2291640T3 (en) | 2008-05-20 | 2019-03-11 | Univ Health Network | Device and method for fluorescence-based imaging and monitoring |
| US8386000B2 (en) * | 2008-09-30 | 2013-02-26 | Covidien Lp | System and method for photon density wave pulse oximetry and pulse hemometry |
| US8433382B2 (en) * | 2008-09-30 | 2013-04-30 | Covidien Lp | Transmission mode photon density wave system and method |
| US20110301500A1 (en) * | 2008-10-29 | 2011-12-08 | Tim Maguire | Automated vessel puncture device using three-dimensional(3d) near infrared (nir) imaging and a robotically driven needle |
| US10492671B2 (en) | 2009-05-08 | 2019-12-03 | Novadaq Technologies ULC | Near infra red fluorescence imaging for visualization of blood vessels during endoscopic harvest |
| CA2762886A1 (en) * | 2009-05-22 | 2010-11-25 | British Columbia Cancer Agency Branch | Selective excitation light fluorescence imaging methods and apparatus |
| US20110060197A1 (en) * | 2009-06-30 | 2011-03-10 | O2 Medtech, Inc. | Near infrared spectrophotometry with enhanced signal to noise performance |
| US8706184B2 (en) * | 2009-10-07 | 2014-04-22 | Intuitive Surgical Operations, Inc. | Methods and apparatus for displaying enhanced imaging data on a clinical image |
| CN102883658B (zh) | 2009-11-19 | 2016-06-22 | 调节成像公司 | 用于使用结构化照明经由单元件检测来分析浑浊介质的方法和设备 |
| TWI498105B (zh) * | 2010-06-11 | 2015-09-01 | Univ Nat Cheng Kung | 外接式腫瘤偵測模組 |
| EP2761327B1 (en) * | 2011-09-30 | 2019-09-18 | The Trustees of Columbia University in the City of New York | Interfacing systems and devices for optical imaging |
| WO2013049677A1 (en) * | 2011-09-30 | 2013-04-04 | The Trustees Of Columbia University In The City Of New York | Compact optical imaging devices, systems, and methods |
| JP6094987B2 (ja) * | 2012-02-20 | 2017-03-15 | 国立大学法人浜松医科大学 | 蛍光検知装置 |
| WO2013163385A1 (en) * | 2012-04-27 | 2013-10-31 | The Research Foundation Of State University Of New York | Self-referencing optical measurement for breast cancer detection |
| EP2863801B8 (en) | 2012-06-21 | 2024-06-12 | Stryker Corporation | Quantification and analysis of angiography and perfusion |
| US10517565B2 (en) | 2012-07-25 | 2019-12-31 | The University Of Connecticut | Dual-probe imaging system and process of using same |
| JP6144131B2 (ja) * | 2012-10-31 | 2017-06-07 | 株式会社東芝 | 超音波診断装置 |
| ES2787384T3 (es) | 2012-11-07 | 2020-10-16 | Modulated Imaging Inc | Formación de imágenes modulada eficiente |
| PL3171765T3 (pl) | 2014-07-24 | 2022-01-03 | University Health Network | Zbieranie i analiza danych do celów diagnostycznych |
| CN107209118B (zh) | 2014-09-29 | 2021-05-28 | 史赛克欧洲运营有限公司 | 在自体荧光存在下生物材料中目标荧光团的成像 |
| AU2014408488B2 (en) | 2014-10-09 | 2019-07-18 | Stryker European Operations Limited | Quantification of absolute blood flow in tissue using fluorescence-mediated photoplethysmography |
| USD775634S1 (en) * | 2014-10-30 | 2017-01-03 | Kardium Inc. | Display screen or portion thereof with animated graphical user interface for a monitoring and control device for an intra-cardiac procedure system |
| USD775141S1 (en) * | 2014-10-30 | 2016-12-27 | Kardium Inc. | Display screen or portion thereof with animated graphical user interface for a monitoring and control device for an intra-cardiac procedure system |
| US11045626B2 (en) | 2016-03-06 | 2021-06-29 | Andrew N. Ellingson | Guide wire device and method |
| US11395593B2 (en) * | 2016-09-14 | 2022-07-26 | Mor Research Applications Ltd. | Device, system and method for detecting irregularities in soft tissue |
| JP6931705B2 (ja) | 2017-02-10 | 2021-09-08 | ノバダック テクノロジーズ ユーエルシー | オープンフィールドハンドヘルド蛍光イメージングシステムおよび方法 |
| KR102404792B1 (ko) * | 2017-10-31 | 2022-06-07 | 한국전기연구원 | 유방암 진단 장치 및 유방암 진단 방법 |
| KR101949346B1 (ko) * | 2018-01-31 | 2019-02-18 | (주)오비이랩 | 복수의 발광부 및 복수의 수광부를 포함하는 모니터링 디바이스를 제어하기 위한 방법, 시스템 및 비일시성의 컴퓨터 판독 가능한 기록 매체 |
| EP3673797B1 (en) * | 2018-12-27 | 2024-06-05 | Polar Electro Oy | Wearable heart activity sensor device |
| US11857299B2 (en) | 2018-12-27 | 2024-01-02 | Polar Electro Oy | Wearable heart activity sensor device |
| CN110367999B (zh) * | 2019-07-17 | 2021-07-09 | 李宏杰 | 一种乳腺血氧功能成像辅以热疗早期乳腺癌检测系统 |
| IT202100008765A1 (it) | 2021-04-12 | 2022-10-12 | Deco Med Srl | Dispositivo non invasivo per la valutazione della perfusione sanguigna del sottocute della mammella |
| GB202314479D0 (en) * | 2023-09-21 | 2023-11-08 | Grand Win Tech Development Limited | Apparatus and method for performing diffuse correlation tomography and/or diffuse optical tomography |
Family Cites Families (139)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE208297C (enExample) | 1900-01-01 | |||
| US2706927A (en) | 1949-08-04 | 1955-04-26 | Research Corp | Apparatus for determining percentage oxygen-saturation of blood |
| US2790438A (en) | 1956-01-13 | 1957-04-30 | Taplin Ronald Harold | Earpieces for oximeters |
| US3068742A (en) | 1959-06-15 | 1962-12-18 | American Optical Corp | Means for performing colorimetry |
| US3412729A (en) | 1965-08-30 | 1968-11-26 | Nasa Usa | Method and apparatus for continuously monitoring blood oxygenation, blood pressure, pulse rate and the pressure pulse curve utilizing an ear oximeter as transducer |
| US3461856A (en) | 1965-10-23 | 1969-08-19 | American Optical Corp | Oximeters |
| US3638640A (en) | 1967-11-01 | 1972-02-01 | Robert F Shaw | Oximeter and method for in vivo determination of oxygen saturation in blood using three or more different wavelengths |
| US3704706A (en) | 1969-10-23 | 1972-12-05 | Univ Drexel | Heart rate and respiratory monitor |
| US3709612A (en) | 1971-03-10 | 1973-01-09 | Miles Lab | Apparatus for measuring reflected light under stabilized light source conditions |
| US3866599A (en) | 1972-01-21 | 1975-02-18 | Univ Washington | Fiberoptic catheter |
| CH581836A5 (enExample) | 1974-08-20 | 1976-11-15 | Contraves Ag | |
| JPS5725217B2 (enExample) | 1974-10-14 | 1982-05-28 | ||
| US4014321A (en) | 1974-11-25 | 1977-03-29 | March Wayne F | Non-invasive glucose sensor system |
| US3958560A (en) | 1974-11-25 | 1976-05-25 | Wayne Front March | Non-invasive automatic glucose sensor system |
| CA1037285A (en) | 1975-04-30 | 1978-08-29 | Glenfield Warner | Ear oximetry process and apparatus |
| US4029085A (en) | 1976-03-26 | 1977-06-14 | Purdue Research Foundation | Method for determining bilirubin concentration from skin reflectance |
| US4119406A (en) | 1976-05-06 | 1978-10-10 | Miles Laboratories, Inc. | Calibration apparatus |
| US4167331A (en) | 1976-12-20 | 1979-09-11 | Hewlett-Packard Company | Multi-wavelength incremental absorbence oximeter |
| US4129125A (en) | 1976-12-27 | 1978-12-12 | Camin Research Corp. | Patient monitoring system |
| US4086652A (en) | 1977-01-19 | 1978-04-25 | Block Engineering, Inc. | Method and apparatus for analyzing a time-dependent phenomenon |
| US4281645A (en) | 1977-06-28 | 1981-08-04 | Duke University, Inc. | Method and apparatus for monitoring metabolism in body organs |
| US4222389A (en) | 1977-10-18 | 1980-09-16 | Institute Of Applied Biology Special Cancer Research Project | Objective determination of the rate of oxygen utilization in peripheral tissue |
| US4162405A (en) | 1978-05-23 | 1979-07-24 | Britton Chance | Flying spot fluoro-meter for oxidized flavoprotein and reduced pyridine nucleotide |
| JPS5524004A (en) | 1978-06-22 | 1980-02-20 | Minolta Camera Kk | Oxymeter |
| US4224948A (en) | 1978-11-24 | 1980-09-30 | Cramer Frank B | Wrist borne pulse meter/chronometer |
| US4416285A (en) | 1978-11-29 | 1983-11-22 | Oximetrix, Inc. | Improved optical catheter and method for making same |
| US4469107A (en) | 1979-01-02 | 1984-09-04 | Asmar Raymond A | Automatic blood pressure measurement device with threshold compensation circuitry and method for performing the same |
| US4259963A (en) | 1979-07-03 | 1981-04-07 | Albert Huch | Multi-purpose transducer for transcutaneous blood measurements |
| US4515165A (en) | 1980-02-04 | 1985-05-07 | Energy Conversion Devices, Inc. | Apparatus and method for detecting tumors |
| GB2068537B (en) | 1980-02-04 | 1984-11-14 | Energy Conversion Devices Inc | Examining biological materials |
| FI64398C (fi) | 1980-08-04 | 1983-11-10 | Outokumpu Oy | Gasblaosroer foer inmatning av reaktionsaemnen i metallurgiskasmaeltor |
| JPS57110928A (en) | 1980-12-27 | 1982-07-10 | Sharp Corp | Thermometer |
| DE3100610C2 (de) | 1981-01-12 | 1983-07-07 | Vladimir Dr.-Ing. Blazek | Meßeinrichtung zur nichtinvasiven Feststellung venöser bzw. arterieller Abfluß- und Durchflußstörungen |
| JPS5826802A (ja) | 1981-08-10 | 1983-02-17 | Sankyo Co Ltd | 農園芸用殺菌剤 |
| US4452250A (en) | 1982-04-29 | 1984-06-05 | Britton Chance | NMR System for the non-invasive study of phosphorus metabilism |
| US4576173A (en) | 1982-06-28 | 1986-03-18 | The Johns Hopkins University | Electro-optical device and method for monitoring instanteous singlet oxygen concentration produced during photoradiation using a CW excitation source |
| CA1204605A (en) | 1982-07-19 | 1986-05-20 | Milton Stoller | Diaphanoscopy method and apparatus |
| US4700708A (en) | 1982-09-02 | 1987-10-20 | Nellcor Incorporated | Calibrated optical oximeter probe |
| EP0102816A3 (en) | 1982-09-02 | 1985-08-28 | Nellcor Incorporated | Pulse oximeter |
| DE3323365C2 (de) | 1982-09-04 | 1994-10-20 | Gsf Forschungszentrum Umwelt | Verfahren und Vorrichtung zur Ausleuchtung von Hohlräumen |
| JPS59168834A (ja) | 1983-03-15 | 1984-09-22 | 松下電工株式会社 | 筋肉疲労度測定装置 |
| US4541438A (en) | 1983-06-02 | 1985-09-17 | The Johns Hopkins University | Localization of cancerous tissue by monitoring infrared fluorescence emitted by intravenously injected porphyrin tumor-specific markers excited by long wavelength light |
| US5139025A (en) | 1983-10-14 | 1992-08-18 | Somanetics Corporation | Method and apparatus for in vivo optical spectroscopic examination |
| US4714341A (en) | 1984-02-23 | 1987-12-22 | Minolta Camera Kabushiki Kaisha | Multi-wavelength oximeter having a means for disregarding a poor signal |
| IT1206462B (it) | 1984-08-07 | 1989-04-27 | Anic Spa | Fotometro a luce impulsata a lunghezza d'onda multipla per monitoraggio non-invasivo. |
| US4807637A (en) | 1984-08-20 | 1989-02-28 | American Science And Engineering, Inc. | Diaphanography method and apparatus |
| US4648892A (en) | 1985-03-22 | 1987-03-10 | Massachusetts Institute Of Technology | Method for making optical shield for a laser catheter |
| US5106387A (en) | 1985-03-22 | 1992-04-21 | Massachusetts Institute Of Technology | Method for spectroscopic diagnosis of tissue |
| FR2579092B1 (fr) | 1985-03-22 | 1989-06-16 | Univ Toulouse | Capteur implantable de pression intracranienne |
| ATE59956T1 (de) | 1985-04-01 | 1991-02-15 | Cosmed Srl | Tragbares atemueberwachungsgeraet zur telemetrie von messwerten einer datenverarbeitungszentrale. |
| US4655225A (en) | 1985-04-18 | 1987-04-07 | Kurabo Industries Ltd. | Spectrophotometric method and apparatus for the non-invasive |
| US4774679A (en) | 1986-02-20 | 1988-09-27 | Carlin John A | Stride evaluation system |
| JPS6323645A (ja) | 1986-05-27 | 1988-01-30 | 住友電気工業株式会社 | 反射加温型オキシメ−タ |
| US4800495A (en) | 1986-08-18 | 1989-01-24 | Physio-Control Corporation | Method and apparatus for processing signals used in oximetry |
| WO1988001485A1 (en) | 1986-09-02 | 1988-03-10 | Singer Jerome R | Infrared radiation imaging system and method |
| US4824242A (en) | 1986-09-26 | 1989-04-25 | Sensormedics Corporation | Non-invasive oximeter and method |
| US4940453A (en) | 1987-01-28 | 1990-07-10 | Cadwell Industries, Inc. | Method and apparatus for magnetically stimulating neurons |
| NO880891L (no) | 1987-03-03 | 1988-09-05 | Elizabeth May Dowling | Fremgangsmaate og apparat for maaling eller deteksjon av konsentrasjonen av en substans. |
| JPS63148307U (enExample) | 1987-03-19 | 1988-09-29 | ||
| US4880304A (en) | 1987-04-01 | 1989-11-14 | Nippon Colin Co., Ltd. | Optical sensor for pulse oximeter |
| US4773422A (en) | 1987-04-30 | 1988-09-27 | Nonin Medical, Inc. | Single channel pulse oximeter |
| JPS63277039A (ja) | 1987-05-08 | 1988-11-15 | Hamamatsu Photonics Kk | 診断装置 |
| FR2617602B1 (fr) | 1987-07-03 | 1989-10-20 | Thomson Csf | Procede et systeme d'imagerie par transillumination a marquage en frequence des photons |
| US4805623A (en) | 1987-09-04 | 1989-02-21 | Vander Corporation | Spectrophotometric method for quantitatively determining the concentration of a dilute component in a light- or other radiation-scattering environment |
| US4836207A (en) | 1987-09-09 | 1989-06-06 | The Beth Israel Hospital Association | Method and apparatus to monitor cholesterol levels with photon correlation spectroscopy |
| US4846183A (en) | 1987-12-02 | 1989-07-11 | The Boc Group, Inc. | Blood parameter monitoring apparatus and methods |
| US4800885A (en) | 1987-12-02 | 1989-01-31 | The Boc Group, Inc. | Blood constituent monitoring apparatus and methods with frequency division multiplexing |
| US4836183A (en) * | 1988-03-22 | 1989-06-06 | Osaka Gas Company, Ltd. | Rotary body room air heater |
| DE3810411A1 (de) | 1988-03-26 | 1989-10-12 | Nicolay Gmbh | Vorrichtung zum fixieren eines messaufnehmers, insbesondere eines messaufnehmers fuer oximetrische messungen |
| US4869254A (en) | 1988-03-30 | 1989-09-26 | Nellcor Incorporated | Method and apparatus for calculating arterial oxygen saturation |
| US5137355A (en) | 1988-06-08 | 1992-08-11 | The Research Foundation Of State University Of New York | Method of imaging a random medium |
| US4951682A (en) | 1988-06-22 | 1990-08-28 | The Cleveland Clinic Foundation | Continuous cardiac output by impedance measurements in the heart |
| US4972331A (en) | 1989-02-06 | 1990-11-20 | Nim, Inc. | Phase modulated spectrophotometry |
| US5402778A (en) | 1993-01-19 | 1995-04-04 | Nim Incorporated | Spectrophotometric examination of tissue of small dimension |
| US5873821A (en) | 1992-05-18 | 1999-02-23 | Non-Invasive Technology, Inc. | Lateralization spectrophotometer |
| US5122974A (en) | 1989-02-06 | 1992-06-16 | Nim, Inc. | Phase modulated spectrophotometry |
| US5596987A (en) | 1988-11-02 | 1997-01-28 | Noninvasive Technology, Inc. | Optical coupler for in vivo examination of biological tissue |
| US5564417A (en) * | 1991-01-24 | 1996-10-15 | Non-Invasive Technology, Inc. | Pathlength corrected oximeter and the like |
| US5111821A (en) | 1988-11-08 | 1992-05-12 | Health Research, Inc. | Fluorometric method for detecting abnormal tissue using dual long-wavelength excitation |
| US4937526A (en) | 1988-11-23 | 1990-06-26 | Mayo Foundation For Medical Education And Research | Adaptive method for reducing motion and flow artifacts in NMR images |
| JPH06103257B2 (ja) | 1988-12-19 | 1994-12-14 | 大塚電子株式会社 | 光散乱を用いた物質の吸光係数測定方法および装置 |
| US5555885A (en) * | 1988-12-21 | 1996-09-17 | Non-Invasive Technology, Inc. | Examination of breast tissue using time-resolved spectroscopy |
| US5386827A (en) * | 1993-03-30 | 1995-02-07 | Nim Incorporated | Quantitative and qualitative in vivo tissue examination using time resolved spectroscopy |
| US5187672A (en) | 1989-02-06 | 1993-02-16 | Nim Incorporated | Phase modulation spectroscopic system |
| US5353799A (en) * | 1991-01-22 | 1994-10-11 | Non Invasive Technology, Inc. | Examination of subjects using photon migration with high directionality techniques |
| US5782755A (en) | 1993-11-15 | 1998-07-21 | Non-Invasive Technology, Inc. | Monitoring one or more solutes in a biological system using optical techniques |
| US5119815A (en) | 1988-12-21 | 1992-06-09 | Nim, Incorporated | Apparatus for determining the concentration of a tissue pigment of known absorbance, in vivo, using the decay characteristics of scintered electromagnetic radiation |
| WO1990009637A1 (en) | 1989-02-13 | 1990-08-23 | Research Corporation Technologies, Inc. | Method and means for parallel frequency acquisition in frequency domain fluorometry |
| US5090415A (en) | 1989-02-14 | 1992-02-25 | Hamamatsu Photonics Kabushiki Kaisha | Examination apparatus |
| GB2228314B (en) | 1989-02-16 | 1992-11-18 | Hamamatsu Photonics Kk | Examination apparatus |
| DD298677A5 (de) | 1989-11-16 | 1992-03-05 | ��������`������������@�������@�������@M�������]k�� | Verfahren zur bestimmung des volumenflusses |
| US5178142A (en) | 1989-05-23 | 1993-01-12 | Vivascan Corporation | Electromagnetic method and apparatus to measure constituents of human or animal tissue |
| JP2798450B2 (ja) | 1989-12-08 | 1998-09-17 | 株式会社日立製作所 | 生体計測装置 |
| GB9011887D0 (en) | 1990-05-26 | 1990-07-18 | Le Fit Ltd | Pulse responsive device |
| US5143081A (en) | 1990-07-27 | 1992-09-01 | New York University | Randomized double pulse stimulus and paired event analysis |
| US5845639A (en) * | 1990-08-10 | 1998-12-08 | Board Of Regents Of The University Of Washington | Optical imaging methods |
| US5251128A (en) | 1990-11-19 | 1993-10-05 | General Electric Company | Motion artifact reduction in projection imaging |
| US5198977A (en) | 1990-11-27 | 1993-03-30 | Jesse Salb | System and method for localization of functional activity in the human brain |
| US5213105A (en) | 1990-12-04 | 1993-05-25 | Research Corporation Technologies, Inc. | Frequency domain optical imaging using diffusion of intensity modulated radiation |
| EP0568628B1 (en) | 1991-01-24 | 1999-09-29 | Non-Invasive Technology, Inc. | Time and frequency domain spectroscopy determining hypoxia |
| US5300097A (en) | 1991-02-13 | 1994-04-05 | Lerner Ethan A | Fiber optic psoriasis treatment device |
| US5067183A (en) | 1991-03-04 | 1991-11-26 | Omar Urquiola | Convertible infant bed assembly |
| US5218962A (en) | 1991-04-15 | 1993-06-15 | Nellcor Incorporated | Multiple region pulse oximetry probe and oximeter |
| DE69229554T2 (de) | 1991-05-16 | 2000-02-10 | Non-Invasive Technology, Inc. | Hämoglobin-messung zur bestimmung von stoffwechselgrössen einer person |
| US5203339A (en) | 1991-06-28 | 1993-04-20 | The Government Of The United States Of America As Represented By The Secretary Of The Department Health And Human Services | Method and apparatus for imaging a physical parameter in turbid media using diffuse waves |
| EP0522674B1 (en) | 1991-07-12 | 1998-11-11 | Mark R. Robinson | Oximeter for reliable clinical determination of blood oxygen saturation in a fetus |
| DE4129438A1 (de) | 1991-09-04 | 1993-03-18 | Siemens Ag | Messanordnung fuer die untersuchung eines objektes mit sichtbarem, nir- oder ir-licht |
| US5309912A (en) | 1991-11-08 | 1994-05-10 | The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services | Multidimensional imaging using a single point detector for a phase encoded modulated optical carrier |
| US5277181A (en) | 1991-12-12 | 1994-01-11 | Vivascan Corporation | Noninvasive measurement of hematocrit and hemoglobin content by differential optical analysis |
| US5413098A (en) | 1991-12-24 | 1995-05-09 | Sextant Medical Corporation | Path constrained spectrophotometer and method for determination of spatial distribution of light or other radiation scattering and absorbing substances in a radiation scattering medium |
| US5853370A (en) * | 1996-09-13 | 1998-12-29 | Non-Invasive Technology, Inc. | Optical system and method for non-invasive imaging of biological tissue |
| JP3107914B2 (ja) * | 1992-07-20 | 2000-11-13 | 浜松ホトニクス株式会社 | 散乱吸収体内部の吸収情報計測装置及び方法 |
| US5949077A (en) | 1992-08-10 | 1999-09-07 | Alfano; Robert R. | Technique for imaging an object in or behind a scattering medium |
| US5408093A (en) | 1992-08-31 | 1995-04-18 | Hitachi, Ltd. | Optical computed tomography equipment having image inverting optical device |
| IL107396A (en) | 1992-11-09 | 1997-02-18 | Boehringer Mannheim Gmbh | Method and apparatus for analytical determination of glucose in a biological matrix |
| US5551423A (en) | 1993-01-26 | 1996-09-03 | Nihon Kohden Corporation | Pulse oximeter probe |
| US5416582A (en) | 1993-02-11 | 1995-05-16 | The United States Of America As Represented By The Department Of Health And Human Services | Method and apparatus for localization and spectroscopy of objects using optical frequency modulation of diffusion waves |
| US5673701A (en) | 1994-10-07 | 1997-10-07 | Non Invasive Technology, Inc. | Optical techniques for examination of biological tissue |
| US6058324A (en) | 1993-06-17 | 2000-05-02 | Non-Invasive Technology, Inc. | Examination and imaging of biological tissue |
| US5983125A (en) | 1993-12-13 | 1999-11-09 | The Research Foundation Of City College Of New York | Method and apparatus for in vivo examination of subcutaneous tissues inside an organ of a body using optical spectroscopy |
| US5497769A (en) | 1993-12-16 | 1996-03-12 | I.S.S. (Usa) Inc. | Photosensor with multiple light sources |
| US5358503A (en) | 1994-01-25 | 1994-10-25 | Bertwell Dale E | Photo-thermal therapeutic device and method |
| US6215587B1 (en) | 1994-02-14 | 2001-04-10 | Robert R. Alfano | Microscope imaging inside highly scattering media |
| US5704355A (en) * | 1994-07-01 | 1998-01-06 | Bridges; Jack E. | Non-invasive system for breast cancer detection |
| JP3310782B2 (ja) * | 1994-07-14 | 2002-08-05 | 株式会社日立製作所 | 吸収物質濃度の空間分布画像化装置 |
| US5582182A (en) * | 1994-10-03 | 1996-12-10 | Sierra Biotechnology Company, Lc | Abnormal dyspnea perception detection system and method |
| US5625458A (en) | 1994-11-10 | 1997-04-29 | Research Foundation Of City College Of New York | Method and system for imaging objects in turbid media using diffusive fermat photons |
| US5596458A (en) * | 1994-12-19 | 1997-01-21 | Integral Peripherals, Inc. | Variable zone layout for information storage disk drive |
| US5706821A (en) | 1994-12-30 | 1998-01-13 | Hamamatsu Photonics K.K. | Spectroscopic method for quantitatively determining the change of concentration of a light or other radiation absorbing compound in a medium which is interrogated through an intervening medium |
| JP3725156B2 (ja) | 1995-01-03 | 2005-12-07 | ノン−インヴェイシヴ テクノロジイ,インク. | 生物組織の生体内検査用の光学カプラ |
| US5655530A (en) | 1995-08-09 | 1997-08-12 | Rio Grande Medical Technologies, Inc. | Method for non-invasive blood analyte measurement with improved optical interface |
| US6108576A (en) | 1996-03-18 | 2000-08-22 | The Research Foundation Of City College Of New York | Time-resolved diffusion tomographic 2D and 3D imaging in highly scattering turbid media |
| US6006001A (en) | 1996-12-02 | 1999-12-21 | The Research Foundation Of Cuny | Fiberoptic assembly useful in optical spectroscopy |
| WO1998025105A1 (en) | 1996-12-04 | 1998-06-11 | The Research Foundation Of City College Of New York | A system and method for performing selected optical measurements |
| RU2127999C1 (ru) * | 1997-01-24 | 1999-03-27 | Лузянин Андрей Геннадьевич | Неинвазивный способ определения параметров гемодинамики в биообъектах и устройство для его осуществления |
| US6091983A (en) | 1997-02-07 | 2000-07-18 | Alfano; Robert R. | Imaging of objects in turbid media based upon the preservation of polarized luminescence emitted from contrast agents |
| US6119033A (en) * | 1997-03-04 | 2000-09-12 | Biotrack, Inc. | Method of monitoring a location of an area of interest within a patient during a medical procedure |
| US6091981A (en) * | 1997-09-16 | 2000-07-18 | Assurance Medical Inc. | Clinical tissue examination |
| JP4733264B2 (ja) * | 1998-02-11 | 2011-07-27 | ノン−インヴェイシヴ テクノロジイ,インク. | 胸部腫瘍の検出、画像形成および特徴表示 |
-
1999
- 1999-02-11 JP JP2000531102A patent/JP4733264B2/ja not_active Expired - Fee Related
- 1999-02-11 CA CA2319454A patent/CA2319454C/en not_active Expired - Fee Related
- 1999-02-11 EP EP99906917A patent/EP1054618B1/en not_active Expired - Lifetime
- 1999-02-11 DE DE69934482T patent/DE69934482T2/de not_active Expired - Lifetime
- 1999-02-11 WO PCT/US1999/002953 patent/WO1999040840A1/en not_active Ceased
-
2004
- 2004-11-08 US US10/983,371 patent/US7627365B2/en not_active Expired - Fee Related
-
2009
- 2009-11-30 US US12/592,638 patent/US20100160752A1/en not_active Abandoned
-
2011
- 2011-03-07 JP JP2011048940A patent/JP2011104427A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| US20100160752A1 (en) | 2010-06-24 |
| JP4733264B2 (ja) | 2011-07-27 |
| WO1999040840A1 (en) | 1999-08-19 |
| JP2011104427A (ja) | 2011-06-02 |
| US7627365B2 (en) | 2009-12-01 |
| JP2002502652A (ja) | 2002-01-29 |
| EP1054618B1 (en) | 2006-12-20 |
| DE69934482D1 (de) | 2007-02-01 |
| CA2319454C (en) | 2010-04-27 |
| US20050197583A1 (en) | 2005-09-08 |
| EP1054618A4 (en) | 2004-07-14 |
| CA2319454A1 (en) | 1999-08-19 |
| EP1054618A1 (en) | 2000-11-29 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| DE69934482T2 (de) | Nachweis, abbildung und kennzeichnung von brustumoren | |
| DE69433205T2 (de) | Oximeter mit weglängen-korrektur | |
| US7904139B2 (en) | Optical examination of biological tissue using non-contact irradiation and detection | |
| Ntziachristos et al. | MRI-guided diffuse optical spectroscopy of malignant and benign breast lesions | |
| JP4733265B2 (ja) | 脳組織の画像形成および特徴表示 | |
| US5899865A (en) | Localization of abnormal breast tissue using time-resolved spectroscopy | |
| DE69738550T2 (de) | Vorrichtung zur klassifizierung von gewebe | |
| DE69727041T2 (de) | Bilderstellung eines trüben Mediums mit Hilfe einer die Randeffekte reduzierenden Flüssigkeit | |
| DE69925869T2 (de) | Laserabbildungsvorrichtung unter Verwendung biomedizinischer Marker, die sich mit Krebszellen verbinden | |
| JP2002502654A (ja) | 組織の腹部横断検査、監視および画像形成 | |
| US20020045833A1 (en) | Medical optical imaging scanner using multiple wavelength simultaneous data acquisition for breast imaging | |
| DE69728105T2 (de) | Auffindung eines objekts in einem trüben medium mittels strahlung verschiedener wellenlänge | |
| US20070287897A1 (en) | Optical Vascular Function Imaging System and Method for Detection and Diagnosis of Cancerous Tumors | |
| Zhou et al. | Portable dual-wavelength amplitude cancellation image system for the determination of human breast tumor | |
| Heusmann et al. | Spectral transillumination of female breasts and breast tissue-like material | |
| Yamashita et al. | The neonate brain (NIR) and breast imaging using transillumination | |
| Lo et al. | Oxygen distribution in the vasculature of mouse tissue in vivo measured using a near infra red phosphor | |
| Cheng et al. | A novel optical scanning system for breast cancer imaging | |
| Srinivasan et al. | Diffuse optical tomography using CW and frequency domain imaging systems | |
| Gao | Diffuse optical tomography | |
| Brukilacchio et al. | Instrumentation for imaging of breast lesions based on coregistered diffuse optical and X-ray tomography | |
| Narasimhalu et al. | Diffuse Optical System for Monitoring Oxygen Pathways In Biological Tissue | |
| Selb et al. | Diffuse optical tomography: time domain | |
| Enfield et al. | Sensitivity and specificity of 3D optical mammography | |
| Jiang | Diffuse optical tomography: Imaging multiple structural and functional features |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 8364 | No opposition during term of opposition |