JP4733264B2 - 胸部腫瘍の検出、画像形成および特徴表示 - Google Patents

胸部腫瘍の検出、画像形成および特徴表示 Download PDF

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JP4733264B2
JP4733264B2 JP2000531102A JP2000531102A JP4733264B2 JP 4733264 B2 JP4733264 B2 JP 4733264B2 JP 2000531102 A JP2000531102 A JP 2000531102A JP 2000531102 A JP2000531102 A JP 2000531102A JP 4733264 B2 JP4733264 B2 JP 4733264B2
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optical system
light
optical
tissue
phase
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JP2002502652A (ja
JP2002502652A5 (enExample
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チャンス,ブリトン
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ノン−インヴェイシヴ テクノロジイ,インク.
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/0059Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence
    • A61B5/0082Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence adapted for particular medical purposes
    • A61B5/0091Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence adapted for particular medical purposes for mammography
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/0059Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence
    • A61B5/0073Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence by tomography, i.e. reconstruction of 3D images from 2D projections
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/145Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue
    • A61B5/1455Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue using optical sensors, e.g. spectral photometrical oximeters
    • A61B5/14551Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue using optical sensors, e.g. spectral photometrical oximeters for measuring blood gases
    • A61B5/14552Details of sensors specially adapted therefor
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/43Detecting, measuring or recording for evaluating the reproductive systems
    • A61B5/4306Detecting, measuring or recording for evaluating the reproductive systems for evaluating the female reproductive systems, e.g. gynaecological evaluations
    • A61B5/4312Breast evaluation or disorder diagnosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B2562/00Details of sensors; Constructional details of sensor housings or probes; Accessories for sensors
    • A61B2562/02Details of sensors specially adapted for in-vivo measurements
    • A61B2562/0233Special features of optical sensors or probes classified in A61B5/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B2562/00Details of sensors; Constructional details of sensor housings or probes; Accessories for sensors
    • A61B2562/02Details of sensors specially adapted for in-vivo measurements
    • A61B2562/0233Special features of optical sensors or probes classified in A61B5/00
    • A61B2562/0242Special features of optical sensors or probes classified in A61B5/00 for varying or adjusting the optical path length in the tissue
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B2562/00Details of sensors; Constructional details of sensor housings or probes; Accessories for sensors
    • A61B2562/04Arrangements of multiple sensors of the same type
    • A61B2562/046Arrangements of multiple sensors of the same type in a matrix array

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Medical Informatics (AREA)
  • Surgery (AREA)
  • Biophysics (AREA)
  • Pathology (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Veterinary Medicine (AREA)
  • Molecular Biology (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Radiology & Medical Imaging (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Optics & Photonics (AREA)
  • Gynecology & Obstetrics (AREA)
  • Reproductive Health (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)
  • Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
JP2000531102A 1998-02-11 1999-02-11 胸部腫瘍の検出、画像形成および特徴表示 Expired - Fee Related JP4733264B2 (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US7450498P 1998-02-11 1998-02-11
US60/074,504 1998-02-11
US9801898P 1998-08-26 1998-08-26
US60/098,018 1998-08-26
PCT/US1999/002953 WO1999040840A1 (en) 1998-02-11 1999-02-11 Detection, imaging and characterization of breast tumors

Related Child Applications (1)

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JP2011048940A Division JP2011104427A (ja) 1998-02-11 2011-03-07 胸部腫瘍の検出、画像形成および特徴表示

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JP2002502652A JP2002502652A (ja) 2002-01-29
JP2002502652A5 JP2002502652A5 (enExample) 2006-04-13
JP4733264B2 true JP4733264B2 (ja) 2011-07-27

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JP2000531102A Expired - Fee Related JP4733264B2 (ja) 1998-02-11 1999-02-11 胸部腫瘍の検出、画像形成および特徴表示
JP2011048940A Pending JP2011104427A (ja) 1998-02-11 2011-03-07 胸部腫瘍の検出、画像形成および特徴表示

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US (2) US7627365B2 (enExample)
EP (1) EP1054618B1 (enExample)
JP (2) JP4733264B2 (enExample)
CA (1) CA2319454C (enExample)
DE (1) DE69934482T2 (enExample)
WO (1) WO1999040840A1 (enExample)

Families Citing this family (74)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE69934482T2 (de) * 1998-02-11 2007-09-27 Non-Invasive Technology, Inc. Nachweis, abbildung und kennzeichnung von brustumoren
DE69941975D1 (de) * 1998-02-13 2010-03-18 Non Invasive Technology Inc Untersuchung, beobachtung und bilddarstellung von abdominal-gewebe
US6949081B1 (en) 1998-08-26 2005-09-27 Non-Invasive Technology, Inc. Sensing and interactive drug delivery
US7840257B2 (en) 2003-01-04 2010-11-23 Non Invasive Technology, Inc. Examination of biological tissue using non-contact optical probes
NL1012943C2 (nl) * 1999-08-31 2001-03-01 Tno Detector en beeldvormende inrichting voor het bepalen van concentratieverhoudingen.
US7006676B1 (en) 2000-01-21 2006-02-28 Medical Optical Imaging, Inc. Method and apparatus for detecting an abnormality within a host medium utilizing frequency-swept modulation diffusion tomography
DE10109539A1 (de) * 2001-02-28 2002-09-12 Siemens Ag Vorrichtung zur Untersuchung von Gewebe mit Licht
JP4781548B2 (ja) * 2001-03-14 2011-09-28 浜松ホトニクス株式会社 乳がん検出装置
US8078262B2 (en) * 2001-04-16 2011-12-13 The Johns Hopkins University Method for imaging and spectroscopy of tumors and determination of the efficacy of anti-tumor drug therapies
GB0213836D0 (en) * 2002-06-14 2002-07-24 Electrode Company The Ltd Analytical apparatus
US7490085B2 (en) * 2002-12-18 2009-02-10 Ge Medical Systems Global Technology Company, Llc Computer-assisted data processing system and method incorporating automated learning
US20040122719A1 (en) * 2002-12-18 2004-06-24 Sabol John M. Medical resource processing system and method utilizing multiple resource type data
US20040122703A1 (en) * 2002-12-19 2004-06-24 Walker Matthew J. Medical data operating model development system and method
DE10332301B4 (de) * 2003-07-16 2009-07-30 Siemens Ag Vorrichtung für die medizinische Diagnose
EP1776652A2 (en) * 2004-08-06 2007-04-25 Invivo Corporation Method and apparatus for positioning a biopsy needle
KR100612863B1 (ko) * 2004-10-11 2006-08-14 삼성전자주식회사 체지방 측정 장치 및 방법
WO2006062895A2 (en) 2004-12-06 2006-06-15 Cambridge Research And Instrumentation, Inc. Systems and methods for in-vivo optical imaging and measurement
US20060239921A1 (en) 2005-04-26 2006-10-26 Novadaq Technologies Inc. Real time vascular imaging during solid organ transplant
WO2006116634A2 (en) 2005-04-26 2006-11-02 Novadaq Technologies, Inc. Method and apparatus for vasculature visualization with applications in neurosurgery and neurology
US20070004972A1 (en) * 2005-06-29 2007-01-04 Johnson & Johnson Consumer Companies, Inc. Handheld device for determining skin age, proliferation status and photodamage level
US20080218732A1 (en) * 2005-07-27 2008-09-11 University Of Massachusetts Lowell Infrared Scanner for Biological Applications
US10231624B2 (en) * 2005-08-10 2019-03-19 Nov Adaq Technologies Ulc Intra-operative head and neck nerve mapping
US20070122344A1 (en) * 2005-09-02 2007-05-31 University Of Rochester Medical Center Office Of Technology Transfer Intraoperative determination of nerve location
EP1954178B1 (en) * 2005-11-23 2018-08-22 Koninklijke Philips N.V. A method and device for imaging an interior of a turbid medium
US20090069695A1 (en) * 2006-03-17 2009-03-12 Koninklijke Philips Electronics N.V. Device for imaging a turbid medium
US8406846B2 (en) * 2006-03-31 2013-03-26 Shimadzu Corporation Mammographic apparatus
GB0607270D0 (en) * 2006-04-11 2006-05-17 Univ Nottingham The pulsing blood supply
US10010277B2 (en) * 2006-06-22 2018-07-03 The General Hospital Corporation Cancer detection by optical measurement of compression-induced transients
JP5887047B2 (ja) 2006-06-22 2016-03-16 コーニンクレッカ フィリップス エヌ ヴェKoninklijke Philips N.V. 断層撮影装置及びコンピュータ断層撮影の再構成方法
GB0613165D0 (en) * 2006-06-28 2006-08-09 Univ Warwick Real-time infrared measurement and imaging system
WO2008015604A2 (en) * 2006-07-31 2008-02-07 Koninklijke Philips Electronics N.V. Measurement with multiplexed detection
US20080161744A1 (en) * 2006-09-07 2008-07-03 University Of Rochester Medical Center Pre-And Intra-Operative Localization of Penile Sentinel Nodes
CA2620949C (en) * 2006-12-22 2015-08-04 New Art Advanced Research Technologies Inc. Method and apparatus for optical image reconstruction using contour determination
US20080177163A1 (en) * 2007-01-19 2008-07-24 O2 Medtech, Inc. Volumetric image formation from optical scans of biological tissue with multiple applications including deep brain oxygenation level monitoring
DE102007047021B4 (de) * 2007-10-01 2011-07-28 Siemens AG, 80333 Anordnung zur Übertragung von Magnetresonanzsignalen
ES2411513T3 (es) * 2007-11-08 2013-07-05 Inolact Ltd. Medición de fluidos excretados de un órgano
DE102007057013A1 (de) * 2007-11-23 2009-05-28 Image Diagnost International Gmbh Verfahren und Vorrichtung zur Verarbeitung digitaler Mammogramme
US8406860B2 (en) 2008-01-25 2013-03-26 Novadaq Technologies Inc. Method for evaluating blush in myocardial tissue
US10219742B2 (en) 2008-04-14 2019-03-05 Novadaq Technologies ULC Locating and analyzing perforator flaps for plastic and reconstructive surgery
US8686698B2 (en) * 2008-04-16 2014-04-01 Enpirion, Inc. Power converter with controller operable in selected modes of operation
EP3372250B1 (en) 2008-05-02 2019-12-25 Novadaq Technologies ULC Methods for production and use of substance-loaded erythrocytes for observation and treatment of microvascular hemodynamics
ES2715633T3 (es) 2008-05-20 2019-06-05 Univ Health Network Dispositivo y método para formación de imágenes y supervisión por fluorescencia
US8433382B2 (en) * 2008-09-30 2013-04-30 Covidien Lp Transmission mode photon density wave system and method
US8386000B2 (en) * 2008-09-30 2013-02-26 Covidien Lp System and method for photon density wave pulse oximetry and pulse hemometry
US20110301500A1 (en) * 2008-10-29 2011-12-08 Tim Maguire Automated vessel puncture device using three-dimensional(3d) near infrared (nir) imaging and a robotically driven needle
US10492671B2 (en) 2009-05-08 2019-12-03 Novadaq Technologies ULC Near infra red fluorescence imaging for visualization of blood vessels during endoscopic harvest
US20120061590A1 (en) * 2009-05-22 2012-03-15 British Columbia Cancer Agency Branch Selective excitation light fluorescence imaging methods and apparatus
US20110060197A1 (en) * 2009-06-30 2011-03-10 O2 Medtech, Inc. Near infrared spectrophotometry with enhanced signal to noise performance
US8706184B2 (en) * 2009-10-07 2014-04-22 Intuitive Surgical Operations, Inc. Methods and apparatus for displaying enhanced imaging data on a clinical image
EP2501288B1 (en) 2009-11-19 2016-12-21 Modulated Imaging Inc. Method and apparatus for analysis of turbid media via single-element detection using structured illumination
TWI498105B (zh) * 2010-06-11 2015-09-01 Univ Nat Cheng Kung 外接式腫瘤偵測模組
US10111594B2 (en) 2011-09-30 2018-10-30 The Trustees Of Columbia University In The City Of New York Compact optical imaging devices, systems, and methods
US10376150B2 (en) * 2011-09-30 2019-08-13 The Trustees Of Columbia University In The City Of New York Interfacing systems, devices, and methods for optical imaging
JP6094987B2 (ja) * 2012-02-20 2017-03-15 国立大学法人浜松医科大学 蛍光検知装置
US9724489B2 (en) * 2012-04-27 2017-08-08 The Research Foundation For The State University Of New York Self-referencing optical measurement for breast cancer detection
EP2863801B8 (en) 2012-06-21 2024-06-12 Stryker Corporation Quantification and analysis of angiography and perfusion
WO2014018728A1 (en) * 2012-07-25 2014-01-30 The University Of Connecticut Dual-probe imaging system and process of using same
JP6144131B2 (ja) * 2012-10-31 2017-06-07 株式会社東芝 超音波診断装置
AU2013341165B2 (en) 2012-11-07 2019-08-01 Modulated Imaging, Inc. Efficient modulated imaging
PL3171765T3 (pl) 2014-07-24 2022-01-03 University Health Network Zbieranie i analiza danych do celów diagnostycznych
US9816930B2 (en) 2014-09-29 2017-11-14 Novadaq Technologies Inc. Imaging a target fluorophore in a biological material in the presence of autofluorescence
CA2963450A1 (en) 2014-10-09 2016-04-14 Novadaq Technologies Inc. Quantification of absolute blood flow in tissue using fluorescence-mediated photoplethysmography
USD775141S1 (en) * 2014-10-30 2016-12-27 Kardium Inc. Display screen or portion thereof with animated graphical user interface for a monitoring and control device for an intra-cardiac procedure system
USD775634S1 (en) * 2014-10-30 2017-01-03 Kardium Inc. Display screen or portion thereof with animated graphical user interface for a monitoring and control device for an intra-cardiac procedure system
US11045626B2 (en) 2016-03-06 2021-06-29 Andrew N. Ellingson Guide wire device and method
US11395593B2 (en) * 2016-09-14 2022-07-26 Mor Research Applications Ltd. Device, system and method for detecting irregularities in soft tissue
EP4242743A3 (en) 2017-02-10 2023-10-18 Stryker European Operations Limited Open-field handheld fluorescence imaging systems and methods
KR102404792B1 (ko) * 2017-10-31 2022-06-07 한국전기연구원 유방암 진단 장치 및 유방암 진단 방법
KR101949346B1 (ko) * 2018-01-31 2019-02-18 (주)오비이랩 복수의 발광부 및 복수의 수광부를 포함하는 모니터링 디바이스를 제어하기 위한 방법, 시스템 및 비일시성의 컴퓨터 판독 가능한 기록 매체
US11857299B2 (en) 2018-12-27 2024-01-02 Polar Electro Oy Wearable heart activity sensor device
EP3673797B1 (en) * 2018-12-27 2024-06-05 Polar Electro Oy Wearable heart activity sensor device
CN110367999B (zh) * 2019-07-17 2021-07-09 李宏杰 一种乳腺血氧功能成像辅以热疗早期乳腺癌检测系统
IT202100008765A1 (it) 2021-04-12 2022-10-12 Deco Med Srl Dispositivo non invasivo per la valutazione della perfusione sanguigna del sottocute della mammella
GB202314479D0 (en) * 2023-09-21 2023-11-08 Grand Win Tech Development Limited Apparatus and method for performing diffuse correlation tomography and/or diffuse optical tomography

Family Cites Families (139)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE208297C (enExample) 1900-01-01
US2706927A (en) * 1949-08-04 1955-04-26 Research Corp Apparatus for determining percentage oxygen-saturation of blood
US2790438A (en) * 1956-01-13 1957-04-30 Taplin Ronald Harold Earpieces for oximeters
US3068742A (en) 1959-06-15 1962-12-18 American Optical Corp Means for performing colorimetry
US3412729A (en) 1965-08-30 1968-11-26 Nasa Usa Method and apparatus for continuously monitoring blood oxygenation, blood pressure, pulse rate and the pressure pulse curve utilizing an ear oximeter as transducer
US3461856A (en) * 1965-10-23 1969-08-19 American Optical Corp Oximeters
US3638640A (en) * 1967-11-01 1972-02-01 Robert F Shaw Oximeter and method for in vivo determination of oxygen saturation in blood using three or more different wavelengths
US3704706A (en) 1969-10-23 1972-12-05 Univ Drexel Heart rate and respiratory monitor
US3709612A (en) * 1971-03-10 1973-01-09 Miles Lab Apparatus for measuring reflected light under stabilized light source conditions
US3866599A (en) * 1972-01-21 1975-02-18 Univ Washington Fiberoptic catheter
CH581836A5 (enExample) 1974-08-20 1976-11-15 Contraves Ag
JPS5725217B2 (enExample) 1974-10-14 1982-05-28
US4014321A (en) * 1974-11-25 1977-03-29 March Wayne F Non-invasive glucose sensor system
US3958560A (en) 1974-11-25 1976-05-25 Wayne Front March Non-invasive automatic glucose sensor system
CA1037285A (en) * 1975-04-30 1978-08-29 Glenfield Warner Ear oximetry process and apparatus
US4029085A (en) * 1976-03-26 1977-06-14 Purdue Research Foundation Method for determining bilirubin concentration from skin reflectance
US4119406A (en) * 1976-05-06 1978-10-10 Miles Laboratories, Inc. Calibration apparatus
US4167331A (en) * 1976-12-20 1979-09-11 Hewlett-Packard Company Multi-wavelength incremental absorbence oximeter
US4129125A (en) 1976-12-27 1978-12-12 Camin Research Corp. Patient monitoring system
US4086652A (en) * 1977-01-19 1978-04-25 Block Engineering, Inc. Method and apparatus for analyzing a time-dependent phenomenon
US4281645A (en) * 1977-06-28 1981-08-04 Duke University, Inc. Method and apparatus for monitoring metabolism in body organs
US4222389A (en) * 1977-10-18 1980-09-16 Institute Of Applied Biology Special Cancer Research Project Objective determination of the rate of oxygen utilization in peripheral tissue
US4162405A (en) * 1978-05-23 1979-07-24 Britton Chance Flying spot fluoro-meter for oxidized flavoprotein and reduced pyridine nucleotide
JPS5524004A (en) * 1978-06-22 1980-02-20 Minolta Camera Kk Oxymeter
US4224948A (en) * 1978-11-24 1980-09-30 Cramer Frank B Wrist borne pulse meter/chronometer
US4416285A (en) 1978-11-29 1983-11-22 Oximetrix, Inc. Improved optical catheter and method for making same
US4469107A (en) * 1979-01-02 1984-09-04 Asmar Raymond A Automatic blood pressure measurement device with threshold compensation circuitry and method for performing the same
US4259963A (en) * 1979-07-03 1981-04-07 Albert Huch Multi-purpose transducer for transcutaneous blood measurements
GB2068537B (en) 1980-02-04 1984-11-14 Energy Conversion Devices Inc Examining biological materials
US4515165A (en) * 1980-02-04 1985-05-07 Energy Conversion Devices, Inc. Apparatus and method for detecting tumors
FI64398C (fi) 1980-08-04 1983-11-10 Outokumpu Oy Gasblaosroer foer inmatning av reaktionsaemnen i metallurgiskasmaeltor
JPS57110928A (en) * 1980-12-27 1982-07-10 Sharp Corp Thermometer
DE3100610C2 (de) 1981-01-12 1983-07-07 Vladimir Dr.-Ing. Blazek Meßeinrichtung zur nichtinvasiven Feststellung venöser bzw. arterieller Abfluß- und Durchflußstörungen
JPS5826802A (ja) 1981-08-10 1983-02-17 Sankyo Co Ltd 農園芸用殺菌剤
US4452250A (en) * 1982-04-29 1984-06-05 Britton Chance NMR System for the non-invasive study of phosphorus metabilism
US4576173A (en) * 1982-06-28 1986-03-18 The Johns Hopkins University Electro-optical device and method for monitoring instanteous singlet oxygen concentration produced during photoradiation using a CW excitation source
AU1687983A (en) 1982-07-19 1984-01-26 Spectrascan Inc. Diaphanoscopy method and apparatus
US4700708A (en) * 1982-09-02 1987-10-20 Nellcor Incorporated Calibrated optical oximeter probe
EP0102816A3 (en) 1982-09-02 1985-08-28 Nellcor Incorporated Pulse oximeter
DE3323365C2 (de) * 1982-09-04 1994-10-20 Gsf Forschungszentrum Umwelt Verfahren und Vorrichtung zur Ausleuchtung von Hohlräumen
JPS59168834A (ja) 1983-03-15 1984-09-22 松下電工株式会社 筋肉疲労度測定装置
US4541438A (en) 1983-06-02 1985-09-17 The Johns Hopkins University Localization of cancerous tissue by monitoring infrared fluorescence emitted by intravenously injected porphyrin tumor-specific markers excited by long wavelength light
US5139025A (en) * 1983-10-14 1992-08-18 Somanetics Corporation Method and apparatus for in vivo optical spectroscopic examination
US4714341A (en) 1984-02-23 1987-12-22 Minolta Camera Kabushiki Kaisha Multi-wavelength oximeter having a means for disregarding a poor signal
IT1206462B (it) * 1984-08-07 1989-04-27 Anic Spa Fotometro a luce impulsata a lunghezza d'onda multipla per monitoraggio non-invasivo.
US4807637A (en) * 1984-08-20 1989-02-28 American Science And Engineering, Inc. Diaphanography method and apparatus
US5106387A (en) * 1985-03-22 1992-04-21 Massachusetts Institute Of Technology Method for spectroscopic diagnosis of tissue
US4648892A (en) * 1985-03-22 1987-03-10 Massachusetts Institute Of Technology Method for making optical shield for a laser catheter
FR2579092B1 (fr) * 1985-03-22 1989-06-16 Univ Toulouse Capteur implantable de pression intracranienne
EP0196396B1 (en) 1985-04-01 1991-01-16 COSMED S.r.l. Portable breathing monitor for telemetric measurement by a central processing station
US4655225A (en) * 1985-04-18 1987-04-07 Kurabo Industries Ltd. Spectrophotometric method and apparatus for the non-invasive
US4774679A (en) * 1986-02-20 1988-09-27 Carlin John A Stride evaluation system
JPS6323645A (ja) * 1986-05-27 1988-01-30 住友電気工業株式会社 反射加温型オキシメ−タ
US4800495A (en) * 1986-08-18 1989-01-24 Physio-Control Corporation Method and apparatus for processing signals used in oximetry
WO1988001485A1 (en) 1986-09-02 1988-03-10 Singer Jerome R Infrared radiation imaging system and method
US4824242A (en) * 1986-09-26 1989-04-25 Sensormedics Corporation Non-invasive oximeter and method
US4940453A (en) * 1987-01-28 1990-07-10 Cadwell Industries, Inc. Method and apparatus for magnetically stimulating neurons
NO880891L (no) 1987-03-03 1988-09-05 Elizabeth May Dowling Fremgangsmaate og apparat for maaling eller deteksjon av konsentrasjonen av en substans.
JPS63148307U (enExample) 1987-03-19 1988-09-29
US4880304A (en) 1987-04-01 1989-11-14 Nippon Colin Co., Ltd. Optical sensor for pulse oximeter
US4773422A (en) * 1987-04-30 1988-09-27 Nonin Medical, Inc. Single channel pulse oximeter
JPS63277039A (ja) 1987-05-08 1988-11-15 Hamamatsu Photonics Kk 診断装置
FR2617602B1 (fr) 1987-07-03 1989-10-20 Thomson Csf Procede et systeme d'imagerie par transillumination a marquage en frequence des photons
US4805623A (en) * 1987-09-04 1989-02-21 Vander Corporation Spectrophotometric method for quantitatively determining the concentration of a dilute component in a light- or other radiation-scattering environment
US4836207A (en) * 1987-09-09 1989-06-06 The Beth Israel Hospital Association Method and apparatus to monitor cholesterol levels with photon correlation spectroscopy
US4846183A (en) * 1987-12-02 1989-07-11 The Boc Group, Inc. Blood parameter monitoring apparatus and methods
US4800885A (en) * 1987-12-02 1989-01-31 The Boc Group, Inc. Blood constituent monitoring apparatus and methods with frequency division multiplexing
US4836183A (en) * 1988-03-22 1989-06-06 Osaka Gas Company, Ltd. Rotary body room air heater
DE3810411A1 (de) * 1988-03-26 1989-10-12 Nicolay Gmbh Vorrichtung zum fixieren eines messaufnehmers, insbesondere eines messaufnehmers fuer oximetrische messungen
US4869254A (en) * 1988-03-30 1989-09-26 Nellcor Incorporated Method and apparatus for calculating arterial oxygen saturation
US5137355A (en) * 1988-06-08 1992-08-11 The Research Foundation Of State University Of New York Method of imaging a random medium
US4951682A (en) * 1988-06-22 1990-08-28 The Cleveland Clinic Foundation Continuous cardiac output by impedance measurements in the heart
US5596987A (en) * 1988-11-02 1997-01-28 Noninvasive Technology, Inc. Optical coupler for in vivo examination of biological tissue
US5122974A (en) * 1989-02-06 1992-06-16 Nim, Inc. Phase modulated spectrophotometry
US5873821A (en) * 1992-05-18 1999-02-23 Non-Invasive Technology, Inc. Lateralization spectrophotometer
US4972331A (en) 1989-02-06 1990-11-20 Nim, Inc. Phase modulated spectrophotometry
US5564417A (en) * 1991-01-24 1996-10-15 Non-Invasive Technology, Inc. Pathlength corrected oximeter and the like
US5402778A (en) 1993-01-19 1995-04-04 Nim Incorporated Spectrophotometric examination of tissue of small dimension
US5111821A (en) * 1988-11-08 1992-05-12 Health Research, Inc. Fluorometric method for detecting abnormal tissue using dual long-wavelength excitation
US4937526A (en) * 1988-11-23 1990-06-26 Mayo Foundation For Medical Education And Research Adaptive method for reducing motion and flow artifacts in NMR images
JPH06103257B2 (ja) * 1988-12-19 1994-12-14 大塚電子株式会社 光散乱を用いた物質の吸光係数測定方法および装置
US5782755A (en) * 1993-11-15 1998-07-21 Non-Invasive Technology, Inc. Monitoring one or more solutes in a biological system using optical techniques
US5119815A (en) 1988-12-21 1992-06-09 Nim, Incorporated Apparatus for determining the concentration of a tissue pigment of known absorbance, in vivo, using the decay characteristics of scintered electromagnetic radiation
US5353799A (en) 1991-01-22 1994-10-11 Non Invasive Technology, Inc. Examination of subjects using photon migration with high directionality techniques
US5555885A (en) * 1988-12-21 1996-09-17 Non-Invasive Technology, Inc. Examination of breast tissue using time-resolved spectroscopy
US5386827A (en) * 1993-03-30 1995-02-07 Nim Incorporated Quantitative and qualitative in vivo tissue examination using time resolved spectroscopy
US5187672A (en) 1989-02-06 1993-02-16 Nim Incorporated Phase modulation spectroscopic system
WO1990009637A1 (en) * 1989-02-13 1990-08-23 Research Corporation Technologies, Inc. Method and means for parallel frequency acquisition in frequency domain fluorometry
US5090415A (en) * 1989-02-14 1992-02-25 Hamamatsu Photonics Kabushiki Kaisha Examination apparatus
GB2228314B (en) 1989-02-16 1992-11-18 Hamamatsu Photonics Kk Examination apparatus
DD298677A5 (de) * 1989-11-16 1992-03-05 ��������`������������@�������@�������@M�������]k�� Verfahren zur bestimmung des volumenflusses
US5178142A (en) * 1989-05-23 1993-01-12 Vivascan Corporation Electromagnetic method and apparatus to measure constituents of human or animal tissue
JP2798450B2 (ja) * 1989-12-08 1998-09-17 株式会社日立製作所 生体計測装置
GB9011887D0 (en) * 1990-05-26 1990-07-18 Le Fit Ltd Pulse responsive device
US5143081A (en) * 1990-07-27 1992-09-01 New York University Randomized double pulse stimulus and paired event analysis
US5845639A (en) * 1990-08-10 1998-12-08 Board Of Regents Of The University Of Washington Optical imaging methods
US5251128A (en) * 1990-11-19 1993-10-05 General Electric Company Motion artifact reduction in projection imaging
US5198977A (en) 1990-11-27 1993-03-30 Jesse Salb System and method for localization of functional activity in the human brain
US5213105A (en) * 1990-12-04 1993-05-25 Research Corporation Technologies, Inc. Frequency domain optical imaging using diffusion of intensity modulated radiation
SG85573A1 (en) 1991-01-24 2002-01-15 Non Invasive Technology Inc Quantitation and localization of tissue hypoxia by time and frequency domain spectroscopy
US5300097A (en) * 1991-02-13 1994-04-05 Lerner Ethan A Fiber optic psoriasis treatment device
US5067183A (en) 1991-03-04 1991-11-26 Omar Urquiola Convertible infant bed assembly
US5218962A (en) * 1991-04-15 1993-06-15 Nellcor Incorporated Multiple region pulse oximetry probe and oximeter
DE69229554T2 (de) 1991-05-16 2000-02-10 Non-Invasive Technology, Inc. Hämoglobin-messung zur bestimmung von stoffwechselgrössen einer person
US5203339A (en) * 1991-06-28 1993-04-20 The Government Of The United States Of America As Represented By The Secretary Of The Department Health And Human Services Method and apparatus for imaging a physical parameter in turbid media using diffuse waves
DE69227545T2 (de) * 1991-07-12 1999-04-29 Robinson, Mark R., Albuquerque, N.Mex. Oximeter zur zuverlässigen klinischen Bestimmung der Blutsauerstoffsättigung in einem Fötus
DE4129438A1 (de) * 1991-09-04 1993-03-18 Siemens Ag Messanordnung fuer die untersuchung eines objektes mit sichtbarem, nir- oder ir-licht
US5309912A (en) * 1991-11-08 1994-05-10 The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services Multidimensional imaging using a single point detector for a phase encoded modulated optical carrier
US5277181A (en) * 1991-12-12 1994-01-11 Vivascan Corporation Noninvasive measurement of hematocrit and hemoglobin content by differential optical analysis
US5413098A (en) * 1991-12-24 1995-05-09 Sextant Medical Corporation Path constrained spectrophotometer and method for determination of spatial distribution of light or other radiation scattering and absorbing substances in a radiation scattering medium
US5853370A (en) * 1996-09-13 1998-12-29 Non-Invasive Technology, Inc. Optical system and method for non-invasive imaging of biological tissue
JP3107914B2 (ja) * 1992-07-20 2000-11-13 浜松ホトニクス株式会社 散乱吸収体内部の吸収情報計測装置及び方法
US5949077A (en) * 1992-08-10 1999-09-07 Alfano; Robert R. Technique for imaging an object in or behind a scattering medium
US5408093A (en) * 1992-08-31 1995-04-18 Hitachi, Ltd. Optical computed tomography equipment having image inverting optical device
IL107396A (en) * 1992-11-09 1997-02-18 Boehringer Mannheim Gmbh Method and apparatus for analytical determination of glucose in a biological matrix
US5551423A (en) * 1993-01-26 1996-09-03 Nihon Kohden Corporation Pulse oximeter probe
US5416582A (en) * 1993-02-11 1995-05-16 The United States Of America As Represented By The Department Of Health And Human Services Method and apparatus for localization and spectroscopy of objects using optical frequency modulation of diffusion waves
US6058324A (en) 1993-06-17 2000-05-02 Non-Invasive Technology, Inc. Examination and imaging of biological tissue
US5673701A (en) * 1994-10-07 1997-10-07 Non Invasive Technology, Inc. Optical techniques for examination of biological tissue
US5983125A (en) 1993-12-13 1999-11-09 The Research Foundation Of City College Of New York Method and apparatus for in vivo examination of subcutaneous tissues inside an organ of a body using optical spectroscopy
US5497769A (en) * 1993-12-16 1996-03-12 I.S.S. (Usa) Inc. Photosensor with multiple light sources
US5358503A (en) * 1994-01-25 1994-10-25 Bertwell Dale E Photo-thermal therapeutic device and method
US6215587B1 (en) * 1994-02-14 2001-04-10 Robert R. Alfano Microscope imaging inside highly scattering media
US5704355A (en) * 1994-07-01 1998-01-06 Bridges; Jack E. Non-invasive system for breast cancer detection
JP3310782B2 (ja) * 1994-07-14 2002-08-05 株式会社日立製作所 吸収物質濃度の空間分布画像化装置
US5582182A (en) * 1994-10-03 1996-12-10 Sierra Biotechnology Company, Lc Abnormal dyspnea perception detection system and method
US5625458A (en) * 1994-11-10 1997-04-29 Research Foundation Of City College Of New York Method and system for imaging objects in turbid media using diffusive fermat photons
US5596458A (en) * 1994-12-19 1997-01-21 Integral Peripherals, Inc. Variable zone layout for information storage disk drive
US5706821A (en) * 1994-12-30 1998-01-13 Hamamatsu Photonics K.K. Spectroscopic method for quantitatively determining the change of concentration of a light or other radiation absorbing compound in a medium which is interrogated through an intervening medium
CN1230118C (zh) 1995-01-03 2005-12-07 无创伤诊断技术公司 用于生物组织体内测量的光耦合器
US5655530A (en) * 1995-08-09 1997-08-12 Rio Grande Medical Technologies, Inc. Method for non-invasive blood analyte measurement with improved optical interface
US6108576A (en) * 1996-03-18 2000-08-22 The Research Foundation Of City College Of New York Time-resolved diffusion tomographic 2D and 3D imaging in highly scattering turbid media
US6006001A (en) 1996-12-02 1999-12-21 The Research Foundation Of Cuny Fiberoptic assembly useful in optical spectroscopy
AU5895998A (en) * 1996-12-04 1998-06-29 Research Foundation Of City College Of New York, The A system and method for performing selected optical measurements
RU2127999C1 (ru) * 1997-01-24 1999-03-27 Лузянин Андрей Геннадьевич Неинвазивный способ определения параметров гемодинамики в биообъектах и устройство для его осуществления
US6091983A (en) * 1997-02-07 2000-07-18 Alfano; Robert R. Imaging of objects in turbid media based upon the preservation of polarized luminescence emitted from contrast agents
US6119033A (en) * 1997-03-04 2000-09-12 Biotrack, Inc. Method of monitoring a location of an area of interest within a patient during a medical procedure
US6091981A (en) * 1997-09-16 2000-07-18 Assurance Medical Inc. Clinical tissue examination
DE69934482T2 (de) * 1998-02-11 2007-09-27 Non-Invasive Technology, Inc. Nachweis, abbildung und kennzeichnung von brustumoren

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