DE69930147D1 - Zwei-schritte-verfahren zur impfung gegen chlamydia - Google Patents

Zwei-schritte-verfahren zur impfung gegen chlamydia

Info

Publication number
DE69930147D1
DE69930147D1 DE69930147T DE69930147T DE69930147D1 DE 69930147 D1 DE69930147 D1 DE 69930147D1 DE 69930147 T DE69930147 T DE 69930147T DE 69930147 T DE69930147 T DE 69930147T DE 69930147 D1 DE69930147 D1 DE 69930147D1
Authority
DE
Germany
Prior art keywords
chlamydia
vaccination against
against chlamydia
steps procedure
administration
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69930147T
Other languages
English (en)
Other versions
DE69930147T2 (de
Inventor
D Murdin
C Brunham
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of Manitoba
Sanofi Pasteur Ltd
Original Assignee
University of Manitoba
Sanofi Pasteur Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by University of Manitoba , Sanofi Pasteur Ltd filed Critical University of Manitoba
Publication of DE69930147D1 publication Critical patent/DE69930147D1/de
Application granted granted Critical
Publication of DE69930147T2 publication Critical patent/DE69930147T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/295Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Chlamydiales (O)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/87Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/51Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biomedical Technology (AREA)
  • Wood Science & Technology (AREA)
  • Biochemistry (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Plant Pathology (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Ophthalmology & Optometry (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
DE69930147T 1998-12-04 1999-12-02 Zwei-schritte-verfahren zur impfung gegen chlamydia Expired - Lifetime DE69930147T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US11085598P 1998-12-04 1998-12-04
US110855P 1998-12-04
PCT/CA1999/001151 WO2000034498A1 (en) 1998-12-04 1999-12-02 Two-step immunization procedure against chlamydia infection

Publications (2)

Publication Number Publication Date
DE69930147D1 true DE69930147D1 (de) 2006-04-27
DE69930147T2 DE69930147T2 (de) 2007-01-11

Family

ID=22335290

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69930147T Expired - Lifetime DE69930147T2 (de) 1998-12-04 1999-12-02 Zwei-schritte-verfahren zur impfung gegen chlamydia

Country Status (10)

Country Link
US (6) US6676949B2 (de)
EP (1) EP1169465B1 (de)
JP (1) JP2002531135A (de)
AT (1) ATE318924T1 (de)
AU (1) AU772356B2 (de)
CA (1) CA2366462C (de)
DE (1) DE69930147T2 (de)
MX (1) MXPA01005615A (de)
NZ (1) NZ512730A (de)
WO (1) WO2000034498A1 (de)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000034498A1 (en) * 1998-12-04 2000-06-15 University Of Manitoba Two-step immunization procedure against chlamydia infection
CA2395499C (en) * 1999-12-22 2011-10-25 Aventis Pasteur Limited Chlamydia antigens and corresponding dna fragments and uses thereof
EP1372705A2 (de) * 2001-03-29 2004-01-02 McGILL UNIVERSITY Leishmania impfstoffe
CA2504938C (en) * 2002-11-07 2011-10-11 Synergy America, Inc. Compositions and methods for treating or preventing pneumococcal infection
US20070060904A1 (en) * 2005-03-14 2007-03-15 Becton, Dickinson And Company Filling system and method for syringes with short needles
EP2413959A4 (de) 2009-01-29 2013-06-19 British Columbia Cancer Agency Chlamydia-antigene umfassende zusammensetzungen
US10258682B2 (en) 2013-01-16 2019-04-16 The United States Of America, As Represented By The Secretary, Department Of Health & Human Services Attenuated chlamydia vaccine

Family Cites Families (71)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4837151A (en) * 1980-05-19 1989-06-06 The Board Of Trustees Of The Leland Stanford Junior University, Stanford University Live vaccines comprising two mutations and foreign antigen
US5643771A (en) * 1980-05-19 1997-07-01 The Board Of Trustees Of The Leland Stanford Junior University Non-reverting live bacterial vaccines
US5821055A (en) 1985-01-14 1998-10-13 Washington Research Foundation Chlamydia major outer membrane protein
EP0192033B1 (de) 1985-01-14 1996-09-25 Chiron Corporation Hauptprotein der Aussenmembran von Chlamydia
IL86583A0 (en) * 1987-06-04 1988-11-15 Molecular Eng Ass Vaccine containing a derivative of a microbe and method for the production thereof
US5869608A (en) * 1989-03-17 1999-02-09 The United States Of America As Represented By The Department Of Health And Human Services Nucleotide and amino acid sequences of the four variable domains of the major outer membrane proteins of Chlamydia trachomatis
AU645489B2 (en) * 1989-03-31 1994-01-20 Washington University Vaccines containing avirulent phoP-type microorganisms
GB8912330D0 (en) * 1989-05-30 1989-07-12 Wellcome Found Live vaccines
TW201794B (de) * 1991-05-03 1993-03-11 American Cyanamid Co
US5840297A (en) * 1993-03-19 1998-11-24 Johns Hopkins University Vaccine comprising anti-idiotypic antibody to chlamydia GLXA and process
CN1134112A (zh) * 1993-11-03 1996-10-23 辉瑞大药厂 衣原体感染的疫苗及治疗方法
US5629167A (en) * 1994-04-19 1997-05-13 Biocine S.P.A. Detection of antibodies against Chlamydia trachomatis pgp3 antigen in patient sera by enzyme-linked immunosorbent assay
US6682729B1 (en) * 1995-05-03 2004-01-27 University Of Maryland, Baltimore Method for introducing and expressing genes in animal cells, and live invasive bacterial vectors for use in the same
US5877159A (en) * 1995-05-03 1999-03-02 University Of Maryland At Baltimore Method for introducing and expressing genes in animal cells and live invasive bacterial vectors for use in the same
GB9516293D0 (en) * 1995-08-09 1995-10-11 Immunova Ltee Novel peptides and their use as vaccines
US6001372A (en) * 1995-08-25 1999-12-14 Wisconsin Alumni Research Foundation Antigenic peptides of Chlamydia trachomatis
WO1997044446A1 (en) * 1996-05-24 1997-11-27 University Of Maryland At Baltimore Dna vaccines for eliciting a mucosal immune response
NZ334114A (en) * 1996-07-12 2000-06-23 Univ Manitoba DNA immunization against chlamydia infection comprising a major outer membrane protein (MOMP) or a MOMP fragment linked to a promoter sequence
US6180398B1 (en) * 1996-07-12 2001-01-30 Virogeneitics Corporation Two-step immunization procedure against the pyramyxoviridae family of viruses using recombinant virus and subunit protein preparation
US6344202B1 (en) * 1996-07-12 2002-02-05 University Of Manitoba DNA immunization against chlaymdia infection
US6696421B2 (en) * 1996-07-12 2004-02-24 University Of Manitoba DNA immunization against chlamydia infection
US6235290B1 (en) * 1997-07-11 2001-05-22 University Of Manitoba DNA immunization against chlaymdia infection
US6464979B1 (en) * 1996-09-12 2002-10-15 Aventis Pasteur Limited Chlamydial vaccines and methods of preparation thereof
US6017735A (en) * 1997-01-23 2000-01-25 Marie Curie Cancer Care Materials and methods for intracellular transport and their uses
EP0977874B1 (de) * 1997-04-18 2005-11-09 Gesellschaft für biotechnologische Forschung mbH (GBF) Abgeschwächter salmonellenstamm, gebraucht als vehikel zur oralen immunisierung
US5935816A (en) * 1997-07-23 1999-08-10 Smithkline Beecham Corporation Chlamydia trachomatis lysS polynucleotides
EP1017409A4 (de) * 1997-08-28 2001-05-16 Univ Louisiana State Vakzine gegen chlamydia psittaci infektionen
US7459524B1 (en) * 1997-10-02 2008-12-02 Emergent Product Development Gaithersburg Inc. Chlamydia protein, sequence and uses thereof
US6024961A (en) * 1997-11-14 2000-02-15 Washington University Recombinant avirulent immunogenic S typhi having rpos positive phenotype
ES2352082T3 (es) * 1997-11-21 2011-02-15 Merck Serono Biodevelopment Polipéptido de la membrana externa de chlamydia pneumoniae, fragmentos del mismo y sus usos, en particular para el diagnóstico, la prevención y el tratamiento de una infección polipéptido de la membrana externa de chlamydia pneumoniae, fragmentos del mismo y sus usos, en particular para el diagnóstico, la prevención y el tratamiento de una infección.
US7041490B1 (en) * 1997-11-28 2006-05-09 Serono Genetics Institute, S.A. Chlamydia trachomatis polynucleotides and vectors, recombinant host cells, DNA chips or kits containing the same
US20020064517A1 (en) * 1998-04-30 2002-05-30 Stewart A. Cederholm-Williams Fibrin sealant as a transfection/transformation vehicle for gene therapy
US6190669B1 (en) * 1998-05-13 2001-02-20 University Of Maryland, Baltimore Attenuated mutants of salmonella which constitutively express the Vi antigen
US6660275B2 (en) * 1998-07-27 2003-12-09 Aventis Pasteur Limited Chlamydia antigens and corresponding DNA fragments and uses thereof
EP1108033A2 (de) * 1998-07-27 2001-06-20 Aventis Pasteur Limited Chlamydia antigene, entsprechende dna fragmente und ihre verwendungen
US20030147924A1 (en) * 1998-07-27 2003-08-07 Aventis Pasteur Limited/Aventis Pasteur Limitee Chlamydia antigens and corresponding dna fragments and uses thereof
US6686339B1 (en) * 1998-08-20 2004-02-03 Aventis Pasteur Limited Nucleic acid molecules encoding inclusion membrane protein C of Chlamydia
US6693087B1 (en) * 1998-08-20 2004-02-17 Aventis Pasteur Limited Nucleic acid molecules encoding POMP91A protein of Chlamydia
EP1105490A1 (de) * 1998-08-20 2001-06-13 Aventis Pasteur Limited Einschlussmembranprotein c von chlamydia kodierende nukleinsäuremoleküle
US6403101B1 (en) * 1998-10-28 2002-06-11 Connaught Laboratories Limited Chlamydia antigens and corresponding DNA fragments and uses thereof
US6649370B1 (en) * 1998-10-28 2003-11-18 Aventis Pasteur Limited Chlamydia antigens and corresponding DNA fragments and uses thereof
US6872814B2 (en) * 1998-10-29 2005-03-29 Aventis Pasteur Limited Chlamydia antigens and corresponding DNA fragments and uses thereof
US6607730B1 (en) * 1998-11-02 2003-08-19 Aventis Pasteur Limited/Aventis Pasteur Limitee Chlamydia antigens and corresponding DNA fragments and uses thereof
US6822071B1 (en) * 1998-11-12 2004-11-23 The Regents Of The University Of California Polypeptides from Chlamydia pneumoniae and their use in the diagnosis, prevention and treatment of disease
AU3790900A (en) * 1998-12-01 2000-06-19 Aventis Pasteur Limited Chlamydia antigens and corresponding DNA fragments and uses thereof
WO2000034498A1 (en) * 1998-12-04 2000-06-15 University Of Manitoba Two-step immunization procedure against chlamydia infection
US6448234B1 (en) * 1998-12-08 2002-09-10 Corixa Corporation Compounds and methods for treatment and diagnosis of chlamydial infection
JP2003512017A (ja) * 1998-12-23 2003-04-02 アベンティス、パストゥール、リミテッド クラミジア抗原および対応するdna断片ならびにその使用
US7297341B1 (en) * 1998-12-23 2007-11-20 Sanofi Pasteur Limited Chlamydia antigens and corresponding DNA fragments and uses thereof
US6808713B1 (en) * 1998-12-28 2004-10-26 Aventis Pasteur Limited Chlamydia antigens and corresponding DNA fragments and uses thereof
NZ512448A (en) * 1998-12-28 2004-01-30 Aventis Pasteur Chlamydia antigens and corresponding DNA fragments and uses thereof
EP2172214A3 (de) * 1999-03-12 2011-03-16 Aventis Pasteur Limited Chlamydia-Antigene und entsprechende DNA-Fragmente sowie Verwendungen davon
DE60036698T2 (de) * 1999-05-03 2008-07-24 Sanofi Pasteur Ltd., Toronto Chlamydia-antigene und entsprechende dna-fragmente und deren verwendungen
US6225443B1 (en) * 1999-05-19 2001-05-01 Wisconsin Alumni Research Foundation Cytotoxic T lymphocyte epitopes of the major outer membrane protein of chlamydia trachomatis
US6191259B1 (en) * 1999-05-19 2001-02-20 Wisconsin Alumni Research Foundation Cytotoxic T lymphocyte epitopes of the major outer membrane protein of chlamydia trachomatis
US6811783B1 (en) * 1999-09-07 2004-11-02 Aventis Pasteur Limited Immunogenic compositions for protection against chlamydial infection
AUPQ275799A0 (en) * 1999-09-10 1999-10-07 Luminis Pty Limited Recombinant bacterium expressing an oligosaccharide receptor mimic
NZ517952A (en) * 1999-09-20 2004-01-30 Aventis Pasteur Chlamydia antigens and corresponding DNA fragments and uses thereof
US6632663B1 (en) * 1999-09-22 2003-10-14 Aventis Pasteur Limited DNA immunization against chlamydia infection
WO2001036455A2 (en) * 1999-11-12 2001-05-25 Aventis Pasteur Limited Chlamydia antigens and corresponding dna fragments and uses thereof
AU2138601A (en) * 1999-12-22 2001-07-03 Aventis Pasteur Limited Chlamydia antigens and corresponding DNA fragments and uses thereof
CA2395499C (en) * 1999-12-22 2011-10-25 Aventis Pasteur Limited Chlamydia antigens and corresponding dna fragments and uses thereof
AU2138501A (en) * 1999-12-22 2001-07-03 Aventis Pasteur Limited Chlamydia antigens and corresponding DNA fragments and uses thereof
US20020132994A1 (en) * 2000-04-04 2002-09-19 Murdin Andrew D. Chlamydia antigens and corresponding DNA fragments and uses thereof
US20030100706A1 (en) * 2000-04-04 2003-05-29 Murdin Andrew D. Chlamydia antigens and corresponding DNA fragments and uses thereof
US20020071831A1 (en) * 2000-04-04 2002-06-13 Murdin Andrew D. Chlamydia antigens and corresponding DNA fragments and uses thereof
US20020094965A1 (en) * 2000-04-04 2002-07-18 Murdin Andrew D. Chlamydia antigens and corresponding DNA fragments and uses thereof
US20020082402A1 (en) * 2000-04-04 2002-06-27 Murdin Andrew D. Chlamydia antigens and corresponding DNA fragments and uses thereof
US20040254130A1 (en) * 2000-05-08 2004-12-16 Murdin Andrew D Chlamydia antigens and corresponding dna fragments and uses thereof
JP3653219B2 (ja) * 2000-10-30 2005-05-25 シャープ株式会社 印刷装置およびそれを用いた通信装置または情報処理装置
AU2005310119A1 (en) * 2004-11-30 2006-06-08 Aeras Global Tb Vaccine Foundation Bacterial packaging strains useful for generation and production of recombinant double-stranded RNA nucleocapsids and uses thereof

Also Published As

Publication number Publication date
WO2000034498A1 (en) 2000-06-15
US20040126382A1 (en) 2004-07-01
MXPA01005615A (es) 2004-08-19
NZ512730A (en) 2003-12-19
EP1169465A1 (de) 2002-01-09
US20080095804A1 (en) 2008-04-24
US20020168382A1 (en) 2002-11-14
CA2366462C (en) 2011-08-09
JP2002531135A (ja) 2002-09-24
US20090215151A1 (en) 2009-08-27
CA2366462A1 (en) 2000-06-15
US7026300B2 (en) 2006-04-11
AU1540700A (en) 2000-06-26
US6676949B2 (en) 2004-01-13
ATE318924T1 (de) 2006-03-15
DE69930147T2 (de) 2007-01-11
US20080182320A1 (en) 2008-07-31
EP1169465B1 (de) 2006-03-01
AU772356B2 (en) 2004-04-22
US20040131630A1 (en) 2004-07-08

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