DE69927048D1 - Ibandroinsäure zur förderung der osseointegration der endoprothesen - Google Patents

Ibandroinsäure zur förderung der osseointegration der endoprothesen

Info

Publication number
DE69927048D1
DE69927048D1 DE69927048T DE69927048T DE69927048D1 DE 69927048 D1 DE69927048 D1 DE 69927048D1 DE 69927048 T DE69927048 T DE 69927048T DE 69927048 T DE69927048 T DE 69927048T DE 69927048 D1 DE69927048 D1 DE 69927048D1
Authority
DE
Germany
Prior art keywords
ibandroinic
endoprothesis
acid
promote osseointegration
osseointegration
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69927048T
Other languages
English (en)
Other versions
DE69927048T2 (de
Inventor
Frieder Bauss
A Kurth
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Roche Diagnostics GmbH
Original Assignee
Roche Diagnostics GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Roche Diagnostics GmbH filed Critical Roche Diagnostics GmbH
Priority to DE69927048T priority Critical patent/DE69927048T2/de
Application granted granted Critical
Publication of DE69927048D1 publication Critical patent/DE69927048D1/de
Publication of DE69927048T2 publication Critical patent/DE69927048T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A61K31/662—Phosphorus acids or esters thereof having P—C bonds, e.g. foscarnet, trichlorfon
    • A61K31/663—Compounds having two or more phosphorus acid groups or esters thereof, e.g. clodronic acid, pamidronic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Immunology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Materials For Medical Uses (AREA)
  • Prostheses (AREA)
DE69927048T 1998-12-04 1999-11-29 Ibandroinsäure zur förderung der osseointegration der endoprothesen Expired - Lifetime DE69927048T2 (de)

Priority Applications (1)

Application Number Priority Date Filing Date Title
DE69927048T DE69927048T2 (de) 1998-12-04 1999-11-29 Ibandroinsäure zur förderung der osseointegration der endoprothesen

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
DE19855976 1998-12-04
DE19855976 1998-12-04
PCT/EP1999/009252 WO2000033849A1 (en) 1998-12-04 1999-11-29 Use of ibandronate for promoting osseointegration of endoprostheses
DE69927048T DE69927048T2 (de) 1998-12-04 1999-11-29 Ibandroinsäure zur förderung der osseointegration der endoprothesen

Publications (2)

Publication Number Publication Date
DE69927048D1 true DE69927048D1 (de) 2005-10-06
DE69927048T2 DE69927048T2 (de) 2006-06-08

Family

ID=7889968

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69927048T Expired - Lifetime DE69927048T2 (de) 1998-12-04 1999-11-29 Ibandroinsäure zur förderung der osseointegration der endoprothesen

Country Status (17)

Country Link
US (1) US6680307B1 (de)
EP (2) EP1614422A3 (de)
JP (1) JP3793023B2 (de)
KR (1) KR100453779B1 (de)
CN (1) CN1173704C (de)
AR (1) AR020017A1 (de)
AT (1) ATE303153T1 (de)
AU (1) AU756540B2 (de)
BR (1) BR9915927A (de)
CA (1) CA2353528C (de)
DE (1) DE69927048T2 (de)
DK (1) DK1135140T3 (de)
ES (1) ES2247842T3 (de)
PT (1) PT1135140E (de)
TR (1) TR200101546T2 (de)
WO (1) WO2000033849A1 (de)
ZA (1) ZA200104140B (de)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2001287260A1 (en) * 2000-07-12 2002-01-21 Ecole Polytechnique Federale De Lausanne (Epfl) Active biocoating for bone implant
EP1228761A3 (de) * 2001-02-01 2003-01-15 Riderway Corporation Flüssige pharmazeutische Zusammensetzung zur Behandlung von Knochenerkrankungen
WO2003055496A1 (en) * 2001-12-21 2003-07-10 The Procter & Gamble Company Method for the treatment of bone disorders
KR20120065435A (ko) * 2002-05-10 2012-06-20 에프. 호프만-라 로슈 아게 골다공증 치료 및 예방용 비스포스폰산
BR0309691A (pt) 2002-12-20 2005-08-02 Hoffmann La Roche Formulação de ibandronato em alta dose
ES2561463T3 (es) * 2003-08-21 2016-02-26 Addbio Ab Dispositivo de implante recubierto con bisfosfonato y método para el mismo
US7582789B2 (en) * 2005-02-01 2009-09-01 Hoffmann-La Roche Inc. Ibandronate polymorph
ES2712644T3 (es) * 2005-02-01 2019-05-14 Atnahs Pharma Uk Ltd Uso médico del polimorfo A de Ibandronato
US8071574B2 (en) * 2005-02-22 2011-12-06 John Dennis Bobyn Implant improving local bone formation

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3623397A1 (de) 1986-07-11 1988-01-14 Boehringer Mannheim Gmbh Neue diphosphonsaeurederivate, verfahren zu deren herstellung und diese verbindungen enthaltende arzneimittel
AU5953894A (en) * 1992-12-23 1994-07-19 Merck & Co., Inc. Bisphosphonate/estrogen therapy for treating and preventing bone loss
US5403829A (en) 1993-03-24 1995-04-04 Leiras Oy Use of bisphosphonates in endo-osteal bone surgery
FI92465C (fi) * 1993-04-14 1994-11-25 Risto Tapani Lehtinen Menetelmä endo-osteaalisten materiaalien käsittelemiseksi
US5646134A (en) 1994-04-21 1997-07-08 Merck & Co., Inc. Alendronate therapy to prevent loosening of, or pain associated with, orthopedic implant devices
GB9408775D0 (en) * 1994-05-04 1994-06-22 Ciba Geigy Ag Use of certain methanebisphosphonic acid derivatives to prevent prothesis loosening and prothesis migration
EP0831756A1 (de) * 1995-06-06 1998-04-01 Merck & Co., Inc. Bisphosphonat-zementzusammensetzung zur verhinderung von aseptischer lockerung orthopädischer prothesen
EP0944312B9 (de) * 1996-12-13 2006-07-05 ZymoGenetics, Inc. Zusammensetzungen und verfahren zum stimulieren von knochenwachstum

Also Published As

Publication number Publication date
AR020017A1 (es) 2002-03-27
BR9915927A (pt) 2001-08-21
KR100453779B1 (ko) 2004-10-20
AU1557700A (en) 2000-06-26
JP3793023B2 (ja) 2006-07-05
DE69927048T2 (de) 2006-06-08
PT1135140E (pt) 2005-10-31
TR200101546T2 (tr) 2001-11-21
EP1135140A1 (de) 2001-09-26
US6680307B1 (en) 2004-01-20
EP1135140B1 (de) 2005-08-31
CN1173704C (zh) 2004-11-03
AU756540B2 (en) 2003-01-16
ES2247842T3 (es) 2006-03-01
EP1614422A3 (de) 2009-02-18
KR20010093137A (ko) 2001-10-27
ATE303153T1 (de) 2005-09-15
DK1135140T3 (da) 2005-12-19
ZA200104140B (en) 2002-08-21
EP1614422A2 (de) 2006-01-11
CN1329495A (zh) 2002-01-02
JP2002531509A (ja) 2002-09-24
WO2000033849A1 (en) 2000-06-15
CA2353528A1 (en) 2000-06-15
CA2353528C (en) 2007-04-24

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Legal Events

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