DE69926629D1 - Transgene fische, die ein von bakteriophagen abgeleitetes transgenes konstrukt zum nachweis von mutationen tragen - Google Patents
Transgene fische, die ein von bakteriophagen abgeleitetes transgenes konstrukt zum nachweis von mutationen tragenInfo
- Publication number
- DE69926629D1 DE69926629D1 DE69926629T DE69926629T DE69926629D1 DE 69926629 D1 DE69926629 D1 DE 69926629D1 DE 69926629 T DE69926629 T DE 69926629T DE 69926629 T DE69926629 T DE 69926629T DE 69926629 D1 DE69926629 D1 DE 69926629D1
- Authority
- DE
- Germany
- Prior art keywords
- nucleic acid
- transgenic
- acid sequence
- bacteriophages
- detection
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 230000035772 mutation Effects 0.000 title abstract 4
- 230000009261 transgenic effect Effects 0.000 title abstract 4
- 238000001514 detection method Methods 0.000 title 1
- 241001515965 unidentified phage Species 0.000 title 1
- 150000007523 nucleic acids Chemical group 0.000 abstract 4
- 108091028043 Nucleic acid sequence Proteins 0.000 abstract 3
- 241000251468 Actinopterygii Species 0.000 abstract 2
- 108700019146 Transgenes Proteins 0.000 abstract 2
- 241000701959 Escherichia virus Lambda Species 0.000 abstract 1
- 230000001580 bacterial effect Effects 0.000 abstract 1
- 238000004166 bioassay Methods 0.000 abstract 1
- 210000004027 cell Anatomy 0.000 abstract 1
- 210000004602 germ cell Anatomy 0.000 abstract 1
- 239000003471 mutagenic agent Substances 0.000 abstract 1
- 108020004707 nucleic acids Proteins 0.000 abstract 1
- 102000039446 nucleic acids Human genes 0.000 abstract 1
- 210000001082 somatic cell Anatomy 0.000 abstract 1
- 230000000392 somatic effect Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K67/00—Rearing or breeding animals, not otherwise provided for; New or modified breeds of animals
- A01K67/027—New or modified breeds of vertebrates
- A01K67/0275—Genetically modified vertebrates, e.g. transgenic
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
- C12N15/8509—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells for producing genetically modified animals, e.g. transgenic
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6897—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids involving reporter genes operably linked to promoters
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2217/00—Genetically modified animals
- A01K2217/05—Animals comprising random inserted nucleic acids (transgenic)
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2227/00—Animals characterised by species
- A01K2227/40—Fish
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2267/00—Animals characterised by purpose
- A01K2267/03—Animal model, e.g. for test or diseases
- A01K2267/0393—Animal model comprising a reporter system for screening tests
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Genetics & Genomics (AREA)
- Zoology (AREA)
- Organic Chemistry (AREA)
- Biotechnology (AREA)
- Wood Science & Technology (AREA)
- General Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Physics & Mathematics (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Environmental Sciences (AREA)
- Microbiology (AREA)
- Veterinary Medicine (AREA)
- Plant Pathology (AREA)
- Animal Husbandry (AREA)
- Biodiversity & Conservation Biology (AREA)
- Analytical Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Immunology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Investigating Or Analysing Materials By Optical Means (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US8743098P | 1998-05-31 | 1998-05-31 | |
US87430P | 1998-05-31 | ||
PCT/US1999/011857 WO1999062333A1 (en) | 1998-05-31 | 1999-05-28 | Bacteriophage-based transgenic fish for mutation detection |
Publications (2)
Publication Number | Publication Date |
---|---|
DE69926629D1 true DE69926629D1 (de) | 2005-09-15 |
DE69926629T2 DE69926629T2 (de) | 2006-06-08 |
Family
ID=22205153
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69926629T Expired - Lifetime DE69926629T2 (de) | 1998-05-31 | 1999-05-28 | Transgene fische, die ein von bakteriophagen abgeleitetes transgenes konstrukt zum nachweis von mutationen tragen |
Country Status (6)
Country | Link |
---|---|
US (1) | US6307121B1 (de) |
EP (1) | EP1083788B1 (de) |
AT (1) | ATE301390T1 (de) |
AU (1) | AU4216099A (de) |
DE (1) | DE69926629T2 (de) |
WO (1) | WO1999062333A1 (de) |
Families Citing this family (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6307121B1 (en) | 1998-05-31 | 2001-10-23 | The University Of Georgia Research Foundation, Inc. | Bacteriophage-based transgenic fish for mutation detection |
US6472583B1 (en) | 1998-10-26 | 2002-10-29 | The University Of Georgia Research Foundation, Inc. | Plasmid-based mutation detection system in transgenic fish |
US7135613B1 (en) | 1999-02-18 | 2006-11-14 | The National University Of Singapore | Chimeric gene constructs for generation of fluorescent transgenic ornamental fish |
US6943025B2 (en) | 2001-01-10 | 2005-09-13 | Children's Medical Center Corporation | Method for identifying genes involved in cell proliferation |
US20050282155A1 (en) * | 2004-06-17 | 2005-12-22 | Lucigen Corporation | Viral libraries from uncultivated viruses and polypeptides produced therefrom |
CN103667327B (zh) * | 2013-12-06 | 2015-10-21 | 中国科学院苏州生物医学工程技术研究所 | 一种用于检测环境污染物的转基因斑马鱼的制备方法 |
MX2021001661A (es) * | 2018-08-10 | 2021-08-11 | Center For Aquaculture Tech Inc | Un método para generar una progenie estéril y monosexo. |
Family Cites Families (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0289121B1 (de) | 1987-05-01 | 1995-12-27 | Stratagene | Mutagenesetest durch Verwendung von nicht menschlichen Lebewesen, die Test-DNS-Sequenzen enthalten |
US5589155A (en) | 1987-05-01 | 1996-12-31 | Union Bank Of California, N.A. | Mutagenesis testing using transgenic non-human animals carrying test DNA sequences |
US5510099A (en) * | 1987-05-01 | 1996-04-23 | Stratagene | Mutagenesis testing using transgenic non-human animals carrying test DNA sequences |
NL8801826A (nl) | 1988-07-19 | 1990-02-16 | Tno | Werkwijze voor het detecteren van mutaties in markergenen. |
JPH06506103A (ja) | 1990-04-05 | 1994-07-14 | ストラタジーン | 試験dna配列を担持するトランスジェニック非ヒト動物を使用する変異誘発性試験 |
EP0578653B1 (de) * | 1991-03-15 | 2001-07-18 | Hsc Research Development Limited Partnership | Genherstellung zur produktion von transgenfisch |
NL9100567A (nl) | 1991-04-02 | 1992-11-02 | Ingeny Bv | Werkwijze voor het detecteren van mutaties, transgeen zoogdier, transgene zoogdiercel, en werkwijze voor het onderzoeken van stoffen of omstandigheden op mutagene eigenschappen. |
CA2130081A1 (en) | 1992-02-14 | 1993-08-19 | Jay M. Short | Mutagenesis testing using transgenic non-human animals carrying test dna sequences |
AU3777693A (en) * | 1992-02-27 | 1993-09-13 | Ohio University | Mutagenicity testing using reporter genes with modified methylation frequencies |
JPH08205708A (ja) | 1995-01-31 | 1996-08-13 | Rikagaku Kenkyusho | トランスジェニック魚類を用いた変異原物質の検出方法 |
FR2734576B1 (fr) | 1995-05-24 | 1997-07-18 | Elf Antar France | Composition lubrifiante pour compresseurs frigorifiques |
EP0842425A1 (de) | 1995-07-28 | 1998-05-20 | Beth Israel Deaconess Medical Center, Inc. | Verfahren und testsatz für die mutagenese-testung |
US6114600A (en) * | 1997-10-31 | 2000-09-05 | The United States Of America As Represented By The Secretary Of Agriculture | Resolution of complex integration patterns to obtain single copy transgenes |
US6307121B1 (en) | 1998-05-31 | 2001-10-23 | The University Of Georgia Research Foundation, Inc. | Bacteriophage-based transgenic fish for mutation detection |
US6472583B1 (en) | 1998-10-26 | 2002-10-29 | The University Of Georgia Research Foundation, Inc. | Plasmid-based mutation detection system in transgenic fish |
-
1999
- 1999-05-28 US US09/322,725 patent/US6307121B1/en not_active Expired - Lifetime
- 1999-05-28 AU AU42160/99A patent/AU4216099A/en not_active Abandoned
- 1999-05-28 WO PCT/US1999/011857 patent/WO1999062333A1/en active IP Right Grant
- 1999-05-28 AT AT99925983T patent/ATE301390T1/de not_active IP Right Cessation
- 1999-05-28 DE DE69926629T patent/DE69926629T2/de not_active Expired - Lifetime
- 1999-05-28 EP EP99925983A patent/EP1083788B1/de not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
AU4216099A (en) | 1999-12-20 |
EP1083788B1 (de) | 2005-08-10 |
US6307121B1 (en) | 2001-10-23 |
DE69926629T2 (de) | 2006-06-08 |
EP1083788A1 (de) | 2001-03-21 |
WO1999062333A1 (en) | 1999-12-09 |
ATE301390T1 (de) | 2005-08-15 |
WO1999062333A9 (en) | 2000-03-09 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition |