DE69925727T2 - Mikroelektrodensystem - Google Patents

Mikroelektrodensystem Download PDF

Info

Publication number
DE69925727T2
DE69925727T2 DE69925727T DE69925727T DE69925727T2 DE 69925727 T2 DE69925727 T2 DE 69925727T2 DE 69925727 T DE69925727 T DE 69925727T DE 69925727 T DE69925727 T DE 69925727T DE 69925727 T2 DE69925727 T2 DE 69925727T2
Authority
DE
Germany
Prior art keywords
microelectrode system
microelectrode
layer
conductive layer
layers
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69925727T
Other languages
German (de)
English (en)
Other versions
DE69925727D1 (de
Inventor
Neville John Freeman
Andrew Mount
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sensorflex Ltd
Original Assignee
Sensorflex Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sensorflex Ltd filed Critical Sensorflex Ltd
Application granted granted Critical
Publication of DE69925727D1 publication Critical patent/DE69925727D1/de
Publication of DE69925727T2 publication Critical patent/DE69925727T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/26Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
    • G01N27/28Electrolytic cell components
    • G01N27/30Electrodes, e.g. test electrodes; Half-cells
    • G01N27/307Disposable laminated or multilayered electrodes
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00277Apparatus
    • B01J2219/00279Features relating to reactor vessels
    • B01J2219/00306Reactor vessels in a multiple arrangement
    • B01J2219/00313Reactor vessels in a multiple arrangement the reactor vessels being formed by arrays of wells in blocks
    • B01J2219/00315Microtiter plates
    • B01J2219/00317Microwell devices, i.e. having large numbers of wells
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00277Apparatus
    • B01J2219/00497Features relating to the solid phase supports
    • B01J2219/00511Walls of reactor vessels
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00583Features relative to the processes being carried out
    • B01J2219/00585Parallel processes
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00583Features relative to the processes being carried out
    • B01J2219/00603Making arrays on substantially continuous surfaces
    • B01J2219/00653Making arrays on substantially continuous surfaces the compounds being bound to electrodes embedded in or on the solid supports
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00583Features relative to the processes being carried out
    • B01J2219/00603Making arrays on substantially continuous surfaces
    • B01J2219/00659Two-dimensional arrays
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/0068Means for controlling the apparatus of the process
    • B01J2219/00702Processes involving means for analysing and characterising the products
    • B01J2219/00704Processes involving means for analysing and characterising the products integrated with the reactor apparatus
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00718Type of compounds synthesised
    • B01J2219/0072Organic compounds
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/26Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
    • G01N27/28Electrolytic cell components
    • G01N27/30Electrodes, e.g. test electrodes; Half-cells
    • G01N27/327Biochemical electrodes, e.g. electrical or mechanical details for in vitro measurements

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Electrochemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Investigating Or Analyzing Materials By The Use Of Electric Means (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Inert Electrodes (AREA)
  • External Artificial Organs (AREA)
  • Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Vehicle Body Suspensions (AREA)
  • Superconductors And Manufacturing Methods Therefor (AREA)
DE69925727T 1998-05-18 1999-05-18 Mikroelektrodensystem Expired - Lifetime DE69925727T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB9810568 1998-05-18
GBGB9810568.7A GB9810568D0 (en) 1998-05-18 1998-05-18 Electrode system
PCT/GB1999/001379 WO1999060392A1 (en) 1998-05-18 1999-05-18 Microelectrode system

Publications (2)

Publication Number Publication Date
DE69925727D1 DE69925727D1 (de) 2005-07-14
DE69925727T2 true DE69925727T2 (de) 2006-06-08

Family

ID=10832202

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69925727T Expired - Lifetime DE69925727T2 (de) 1998-05-18 1999-05-18 Mikroelektrodensystem

Country Status (8)

Country Link
US (1) US6811663B1 (https=)
EP (1) EP1078253B1 (https=)
JP (1) JP4531977B2 (https=)
AT (1) ATE297551T1 (https=)
AU (1) AU3937899A (https=)
DE (1) DE69925727T2 (https=)
GB (1) GB9810568D0 (https=)
WO (1) WO1999060392A1 (https=)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102007047078A1 (de) * 2007-10-01 2009-04-02 Robert Bosch Gmbh Sensorelement zur Detektion von Partikeln in einem Gas und Verfahren zu dessen Herstellung
WO2016102636A1 (de) * 2014-12-23 2016-06-30 Heraeus Sensor Technology Gmbh Sensor zur detektion elektrisch leitfähiger und/oder polarisierbarer partikel, sensorsystem, verfahren zum betreiben eines sensors, verfahren zur herstellung eines derartigen sensors und verwendung eines derartigen sensors

Families Citing this family (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19907164C2 (de) * 1999-02-19 2002-10-24 Micronas Gmbh Meßeinrichtung sowie Verfahren zu deren Herstellung
CA2393766A1 (en) * 1999-12-15 2001-06-21 George N. Maracas Column and row addressable high density biochip array
WO2002097461A1 (en) * 2001-05-24 2002-12-05 Alan Glyn Jones Sensing an electric, magnetic or electromagnetic field
GB2377026A (en) * 2001-06-29 2002-12-31 Imp College Innovations Ltd Electrically addressable electrochemical cell array
US7074519B2 (en) * 2001-10-26 2006-07-11 The Regents Of The University Of California Molehole embedded 3-D crossbar architecture used in electrochemical molecular memory device
GB0130684D0 (en) 2001-12-21 2002-02-06 Oxford Biosensors Ltd Micro-band electrode
GB0211449D0 (en) 2002-05-17 2002-06-26 Oxford Biosensors Ltd Analyte measurement
JP3894943B2 (ja) * 2003-02-17 2007-03-22 東洋精密工業株式会社 線状デバイス
GB2398751A (en) * 2003-02-28 2004-09-01 Univ Surrey A dielectrophoretic separation device
US7357851B2 (en) 2003-09-30 2008-04-15 Abbott Laboratories Electrochemical cell
US7501301B2 (en) * 2004-03-10 2009-03-10 The Board Of Trustees Of The Leland Stanford Junior University Low cost fabrication of microelectrode arrays for cell-based biosensors and drug discovery methods
GB0414546D0 (en) * 2004-06-29 2004-08-04 Oxford Biosensors Ltd Electrode for electrochemical sensor
JP4750394B2 (ja) * 2004-09-10 2011-08-17 三菱化学メディエンス株式会社 多層電極及び多層電極カートリッジ、電気化学分析装置及び電気化学分析方法、電気化学発光分析装置及び電気化学発光分析方法、並びに電気化学発光素子
GB0516783D0 (en) * 2005-08-16 2005-09-21 Univ Surrey Micro-electrode device for dielectrophoretic characterisation of particles
US7741142B2 (en) * 2005-11-22 2010-06-22 Hewlett-Packard Development Company, L.P. Method of fabricating a biosensor
JP4982899B2 (ja) * 2006-01-24 2012-07-25 独立行政法人産業技術総合研究所 微小電極およびその製造方法
JP4635258B2 (ja) * 2006-03-02 2011-02-23 独立行政法人産業技術総合研究所 バイオセンサー
EP2002248A1 (en) 2006-03-17 2008-12-17 Element Six Limited Microelectrode array
WO2008005736A1 (en) * 2006-06-30 2008-01-10 3M Innovative Properties Company Flexible circuit
US20080233011A1 (en) * 2007-03-23 2008-09-25 3M Innovative Properties Company Microfluidic devices
JP5004705B2 (ja) * 2007-07-20 2012-08-22 コバレントマテリアル株式会社 微細流路構造体及び微細流路構造体の製造方法
US20100030052A1 (en) * 2008-07-31 2010-02-04 Bommakanti Balasubrahmanya S Analyte sensors comprising plasticizers
GB0821810D0 (en) * 2008-11-28 2009-01-07 Nanoflex Ltd Electrode assembly
JP5577498B2 (ja) * 2010-09-17 2014-08-27 北斗電工株式会社 ウェルユニット及び検体セル
WO2014085655A1 (en) * 2012-11-29 2014-06-05 Indiana University Research And Technology Corporation Dielectric electrolyte measurement device
CN104792845A (zh) * 2014-08-07 2015-07-22 中国科学院微电子研究所 传感装置
DE102016107888A1 (de) * 2016-04-28 2017-11-02 Heraeus Sensor Technology Gmbh Sensor zur Detektion elektrisch leitfähiger und/oder polarisierbarer Partikel, Sensorsystem, Verfahren zum Betreiben eines Sensors und Verwendung eines derartigen Sensors
FR3061303A1 (fr) * 2016-12-23 2018-06-29 Universite Paris Diderot Paris 7 Dispositif de cellules electrochimiques et systeme de mesure electrochimique comprenant un tel dispositif
US12059689B2 (en) 2019-09-23 2024-08-13 Korea Institute Of Science And Technology Filter for trapping particulate matter including vertical nano-gap electrode with plurality of holes and air conditioning apparatus having the same
CN114660140B (zh) * 2020-12-23 2024-02-23 北京京东方技术开发有限公司 生物检测装置、生物芯片、微电极结构及其制备方法
CN114652291B (zh) * 2020-12-23 2025-06-27 北京京东方技术开发有限公司 生物检测装置、系统及方法

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU535261B2 (en) 1979-11-27 1984-03-08 Asahi Glass Company Limited Ion exchange membrane cell
JPS5938647A (ja) * 1982-08-28 1984-03-02 Toshiba Corp イオン選択性電極装置と流通型イオン分析装置
JPS59102042A (ja) 1982-11-30 1984-06-12 松下電工株式会社 天井材の製法
DE4032436A1 (de) * 1990-10-12 1992-04-16 Bosch Gmbh Robert Sensorelement fuer grenzstromsensoren zur bestimmung des (gamma)-wertes von gasgemischen
DE4115414C2 (de) * 1991-05-10 1995-07-06 Meinhard Prof Dr Knoll Verfahren zur Herstellung von miniaturisierten Chemo- und Biosensorelementen mit ionenselektiver Membran sowie von Trägern für diese Elemente
US5846708A (en) * 1991-11-19 1998-12-08 Massachusetts Institiute Of Technology Optical and electrical methods and apparatus for molecule detection
DE69333945T2 (de) 1992-09-04 2006-06-29 Matsushita Electric Industrial Co., Ltd., Kadoma Flache Elektrode
JP3291838B2 (ja) * 1993-05-12 2002-06-17 東陶機器株式会社 バイオセンサ及びその製造方法
IL109492A (en) 1994-05-01 1999-06-20 Sirotech Ltd Method and apparatus for evaluating bacterial populations
JP3548919B2 (ja) * 1995-07-07 2004-08-04 カシオ計算機株式会社 バイオセンサ
GB9526652D0 (en) * 1995-12-29 1996-02-28 Shine Thomas A Electrode assembly
US5727977A (en) * 1996-03-04 1998-03-17 Motorola, Inc. Process for manufacturing a field-emission device
DE19645653A1 (de) 1996-11-06 1998-05-07 Herbert Hosse Filterelemente und Filtervorrichtungen
DE29717809U1 (de) * 1997-10-07 1998-03-05 Kurt-Schwabe-Institut für Meß- und Sensortechnik e.V., 04736 Meinsberg Elektrochemische Arrayelektrode

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102007047078A1 (de) * 2007-10-01 2009-04-02 Robert Bosch Gmbh Sensorelement zur Detektion von Partikeln in einem Gas und Verfahren zu dessen Herstellung
WO2016102636A1 (de) * 2014-12-23 2016-06-30 Heraeus Sensor Technology Gmbh Sensor zur detektion elektrisch leitfähiger und/oder polarisierbarer partikel, sensorsystem, verfahren zum betreiben eines sensors, verfahren zur herstellung eines derartigen sensors und verwendung eines derartigen sensors
WO2016102635A1 (de) * 2014-12-23 2016-06-30 Heraeus Sensor Technology Gmbh Sensor zur detektion elektrisch leitfähiger und/oder polarisierbarer partikel, sensorsystem, verfahren zum betreiben eines sensors, verfahren zur herstellung eines derartigen sensors und verwendung eines derartigen sensors
US10705002B2 (en) 2014-12-23 2020-07-07 Heraeus Nexensos Gmbh Sensor for detecting electrically conductive and/or polarizable particles and method for adjusting such a sensor

Also Published As

Publication number Publication date
US6811663B1 (en) 2004-11-02
JP2002515603A (ja) 2002-05-28
EP1078253B1 (en) 2005-06-08
WO1999060392A1 (en) 1999-11-25
ATE297551T1 (de) 2005-06-15
DE69925727D1 (de) 2005-07-14
GB9810568D0 (en) 1998-07-15
JP4531977B2 (ja) 2010-08-25
EP1078253A1 (en) 2001-02-28
AU3937899A (en) 1999-12-06
WO1999060392A9 (en) 2001-04-05

Similar Documents

Publication Publication Date Title
DE69925727T2 (de) Mikroelektrodensystem
EP0385964B1 (de) Biosensoranordnung
DE69800630T2 (de) Chip zur elektroforetischen Trennung von Molekülen und Verfahren zur Verwendung desselben
DE60020076T2 (de) Kleinvolumiger in-vitro-analyt-sensor
DE60105979T2 (de) Verfahren zur herstellung von mikrostrukturen mit verschiedenen oberflächeneigenschaften in einem multischichtkörper durch plasmaätzen
DE69219171T2 (de) Gassensoren
EP1030174B1 (de) Messeinrichtung sowie Verfahren zu deren Herstellung
DE2142628A1 (de) Elektrophorese Gerat
DE102014116777A1 (de) Mikrofluidischer Sensor
DE102004044299A1 (de) Vorrichtung und Verfahren zum Nachweis von geladenen Makromolekülen
DE68928441T2 (de) Ein Feuchtigkeitssensor unter Verwendung einer elektrochemischen Zelle
LU505730B1 (de) Eine zellelektrofusionschipvorrichtung und präparationsverfahren basierend auf einer anordnung von gepaarten strukturen mit bilateralen flussfeldern
EP1573328B1 (de) Bio-chip
DE19631530C2 (de) Ionenselektiver Sensor
EP2739965B1 (de) Elektrochemischer sensor
DE4232729C2 (de) Mikrobezugselektrode zur Erzeugung eines konstanten Bezugs- oder Referenzpotentials
DE102005003910B4 (de) Elektrochemisches Transducer-Array und dessen Verwendung
WO2012107014A1 (de) Verfahren zur herstellung einer vorrichtung zum nachweis eines analyten sowie vorrichtung und deren verwendung
DE19628052C1 (de) Sensor- und/oder Trennelement sowie Verfahren zu dessen Herstellung und Anwendung desselben
WO2007003399A2 (de) Elektrodenanordnung, deren verwendung sowie verfahren zu deren herstellung
DE19949538C2 (de) Mikrokapillare und Verfahren zu deren Herstellung
EP1202792B1 (de) Verfahren und vorrichtung zur elektrophoretischen trennung von partikeln, insbesondere von makromolekülen
WO2002093153A1 (de) Elektrochemische durchflussmesszelle
DE112021007658T5 (de) Vorrichtung zur analyse biologischer proben
WO2000058721A1 (de) Elektrophoresechip sowie gerät zum betreiben eines elektrophoresechips

Legal Events

Date Code Title Description
8332 No legal effect for de
8370 Indication related to discontinuation of the patent is to be deleted
8364 No opposition during term of opposition
8328 Change in the person/name/address of the agent

Representative=s name: LENZING GERBER STUTE PARTNERSCHAFTSGESELLSCHAFT VO

R082 Change of representative

Ref document number: 1078253

Country of ref document: EP

Representative=s name: LENZING GERBER STUTE PARTNERSCHAFTSGESELLSCHAF, DE