DE69923167T2 - Membran mit gewellter Oberfläche zur Führung des Gewebes - Google Patents
Membran mit gewellter Oberfläche zur Führung des Gewebes Download PDFInfo
- Publication number
- DE69923167T2 DE69923167T2 DE69923167T DE69923167T DE69923167T2 DE 69923167 T2 DE69923167 T2 DE 69923167T2 DE 69923167 T DE69923167 T DE 69923167T DE 69923167 T DE69923167 T DE 69923167T DE 69923167 T2 DE69923167 T2 DE 69923167T2
- Authority
- DE
- Germany
- Prior art keywords
- implant
- bone
- tissue
- corrugation
- membrane
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
- 239000012528 membrane Substances 0.000 title abstract description 193
- 239000004744 fabric Substances 0.000 title description 7
- 210000000988 bone and bone Anatomy 0.000 claims abstract description 296
- 230000007547 defect Effects 0.000 claims abstract description 139
- 239000007943 implant Substances 0.000 claims abstract description 71
- 210000001519 tissue Anatomy 0.000 claims abstract description 56
- 239000000463 material Substances 0.000 claims description 82
- 239000003795 chemical substances by application Substances 0.000 claims description 21
- 239000000126 substance Substances 0.000 claims description 13
- 229920000642 polymer Polymers 0.000 claims description 11
- 238000003780 insertion Methods 0.000 claims description 10
- 230000037431 insertion Effects 0.000 claims description 10
- 239000012530 fluid Substances 0.000 claims description 8
- 230000015572 biosynthetic process Effects 0.000 claims description 6
- 230000012010 growth Effects 0.000 claims description 4
- 238000007373 indentation Methods 0.000 claims description 4
- 238000005728 strengthening Methods 0.000 claims description 4
- 239000003814 drug Substances 0.000 claims description 3
- 229940079593 drug Drugs 0.000 claims description 3
- 239000000835 fiber Substances 0.000 claims description 2
- 239000010410 layer Substances 0.000 claims 6
- 239000002356 single layer Substances 0.000 claims 1
- 210000004872 soft tissue Anatomy 0.000 abstract description 32
- 239000011148 porous material Substances 0.000 abstract description 17
- 208000006735 Periostitis Diseases 0.000 abstract description 11
- 210000003460 periosteum Anatomy 0.000 abstract description 11
- 230000008439 repair process Effects 0.000 abstract description 7
- 210000001608 connective tissue cell Anatomy 0.000 abstract description 6
- 230000006378 damage Effects 0.000 abstract description 3
- 238000000338 in vitro Methods 0.000 abstract description 3
- 210000005166 vasculature Anatomy 0.000 abstract 1
- 230000010478 bone regeneration Effects 0.000 description 100
- 230000001681 protective effect Effects 0.000 description 86
- 210000004027 cell Anatomy 0.000 description 30
- 210000004204 blood vessel Anatomy 0.000 description 29
- 238000000034 method Methods 0.000 description 21
- 208000012287 Prolapse Diseases 0.000 description 18
- 210000002919 epithelial cell Anatomy 0.000 description 13
- 239000012634 fragment Substances 0.000 description 11
- 230000003239 periodontal effect Effects 0.000 description 11
- 208000010392 Bone Fractures Diseases 0.000 description 10
- 230000000735 allogeneic effect Effects 0.000 description 10
- 230000008929 regeneration Effects 0.000 description 10
- 238000011069 regeneration method Methods 0.000 description 10
- 239000012744 reinforcing agent Substances 0.000 description 10
- 206010017076 Fracture Diseases 0.000 description 9
- 210000000214 mouth Anatomy 0.000 description 9
- 210000003205 muscle Anatomy 0.000 description 9
- 230000011164 ossification Effects 0.000 description 9
- 230000002787 reinforcement Effects 0.000 description 9
- RTAQQCXQSZGOHL-UHFFFAOYSA-N Titanium Chemical compound [Ti] RTAQQCXQSZGOHL-UHFFFAOYSA-N 0.000 description 8
- 210000002901 mesenchymal stem cell Anatomy 0.000 description 8
- 102000004169 proteins and genes Human genes 0.000 description 8
- 108090000623 proteins and genes Proteins 0.000 description 8
- 238000001356 surgical procedure Methods 0.000 description 8
- 238000010521 absorption reaction Methods 0.000 description 7
- 230000002138 osteoinductive effect Effects 0.000 description 7
- 230000008901 benefit Effects 0.000 description 6
- 210000002808 connective tissue Anatomy 0.000 description 6
- 239000003102 growth factor Substances 0.000 description 6
- 230000000921 morphogenic effect Effects 0.000 description 6
- 210000003625 skull Anatomy 0.000 description 6
- 230000006870 function Effects 0.000 description 5
- 230000035876 healing Effects 0.000 description 5
- 230000001172 regenerating effect Effects 0.000 description 5
- 230000003014 reinforcing effect Effects 0.000 description 5
- 210000000601 blood cell Anatomy 0.000 description 4
- 230000012292 cell migration Effects 0.000 description 4
- 210000003981 ectoderm Anatomy 0.000 description 4
- 238000002513 implantation Methods 0.000 description 4
- 239000004632 polycaprolactone Substances 0.000 description 4
- 230000008569 process Effects 0.000 description 4
- 230000035755 proliferation Effects 0.000 description 4
- 210000002435 tendon Anatomy 0.000 description 4
- 230000005540 biological transmission Effects 0.000 description 3
- 210000004369 blood Anatomy 0.000 description 3
- 239000008280 blood Substances 0.000 description 3
- 230000036770 blood supply Effects 0.000 description 3
- 210000000845 cartilage Anatomy 0.000 description 3
- 239000002131 composite material Substances 0.000 description 3
- 230000002950 deficient Effects 0.000 description 3
- 230000009477 glass transition Effects 0.000 description 3
- 208000015181 infectious disease Diseases 0.000 description 3
- 230000033001 locomotion Effects 0.000 description 3
- 210000004373 mandible Anatomy 0.000 description 3
- 239000011159 matrix material Substances 0.000 description 3
- 210000003716 mesoderm Anatomy 0.000 description 3
- 239000005445 natural material Substances 0.000 description 3
- 230000004820 osteoconduction Effects 0.000 description 3
- 230000002269 spontaneous effect Effects 0.000 description 3
- 238000002054 transplantation Methods 0.000 description 3
- 208000035143 Bacterial infection Diseases 0.000 description 2
- 206010065687 Bone loss Diseases 0.000 description 2
- 206010029113 Neovascularisation Diseases 0.000 description 2
- 206010041662 Splinter Diseases 0.000 description 2
- 208000022362 bacterial infectious disease Diseases 0.000 description 2
- 230000004888 barrier function Effects 0.000 description 2
- 229920000704 biodegradable plastic Polymers 0.000 description 2
- 210000002449 bone cell Anatomy 0.000 description 2
- 230000024245 cell differentiation Effects 0.000 description 2
- 230000004663 cell proliferation Effects 0.000 description 2
- 239000000919 ceramic Substances 0.000 description 2
- 230000003399 chemotactic effect Effects 0.000 description 2
- 210000000038 chest Anatomy 0.000 description 2
- 229940124447 delivery agent Drugs 0.000 description 2
- 238000011161 development Methods 0.000 description 2
- 230000018109 developmental process Effects 0.000 description 2
- 238000006073 displacement reaction Methods 0.000 description 2
- 238000009826 distribution Methods 0.000 description 2
- 210000001900 endoderm Anatomy 0.000 description 2
- 230000007613 environmental effect Effects 0.000 description 2
- 210000000981 epithelium Anatomy 0.000 description 2
- 230000007717 exclusion Effects 0.000 description 2
- 238000001727 in vivo Methods 0.000 description 2
- 230000002401 inhibitory effect Effects 0.000 description 2
- 238000012432 intermediate storage Methods 0.000 description 2
- 230000014759 maintenance of location Effects 0.000 description 2
- 238000004519 manufacturing process Methods 0.000 description 2
- 230000007246 mechanism Effects 0.000 description 2
- 230000008384 membrane barrier Effects 0.000 description 2
- 229910052751 metal Inorganic materials 0.000 description 2
- 239000002184 metal Substances 0.000 description 2
- 230000002297 mitogenic effect Effects 0.000 description 2
- 238000012986 modification Methods 0.000 description 2
- 230000004048 modification Effects 0.000 description 2
- 230000000399 orthopedic effect Effects 0.000 description 2
- 230000004819 osteoinduction Effects 0.000 description 2
- 206010003694 Atrophy Diseases 0.000 description 1
- 235000014653 Carica parviflora Nutrition 0.000 description 1
- 241000243321 Cnidaria Species 0.000 description 1
- 102000008186 Collagen Human genes 0.000 description 1
- 108010035532 Collagen Proteins 0.000 description 1
- 102000018233 Fibroblast Growth Factor Human genes 0.000 description 1
- 108050007372 Fibroblast Growth Factor Proteins 0.000 description 1
- 241000282412 Homo Species 0.000 description 1
- 108090000723 Insulin-Like Growth Factor I Proteins 0.000 description 1
- 241000124008 Mammalia Species 0.000 description 1
- 241001465754 Metazoa Species 0.000 description 1
- 206010028980 Neoplasm Diseases 0.000 description 1
- 102000010780 Platelet-Derived Growth Factor Human genes 0.000 description 1
- 108010038512 Platelet-Derived Growth Factor Proteins 0.000 description 1
- 208000002607 Pseudarthrosis Diseases 0.000 description 1
- 206010061363 Skeletal injury Diseases 0.000 description 1
- 102000013275 Somatomedins Human genes 0.000 description 1
- 230000005856 abnormality Effects 0.000 description 1
- 239000004480 active ingredient Substances 0.000 description 1
- 239000003242 anti bacterial agent Substances 0.000 description 1
- 230000003110 anti-inflammatory effect Effects 0.000 description 1
- 230000001028 anti-proliverative effect Effects 0.000 description 1
- 229940088710 antibiotic agent Drugs 0.000 description 1
- 239000002246 antineoplastic agent Substances 0.000 description 1
- 210000000436 anus Anatomy 0.000 description 1
- 230000037444 atrophy Effects 0.000 description 1
- 238000005452 bending Methods 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 239000000560 biocompatible material Substances 0.000 description 1
- 239000012620 biological material Substances 0.000 description 1
- 230000036760 body temperature Effects 0.000 description 1
- 230000008468 bone growth Effects 0.000 description 1
- 210000002805 bone matrix Anatomy 0.000 description 1
- 201000011510 cancer Diseases 0.000 description 1
- 239000000969 carrier Substances 0.000 description 1
- 230000008859 change Effects 0.000 description 1
- 229940044683 chemotherapy drug Drugs 0.000 description 1
- 238000004140 cleaning Methods 0.000 description 1
- 229920001436 collagen Polymers 0.000 description 1
- 230000006835 compression Effects 0.000 description 1
- 238000007906 compression Methods 0.000 description 1
- 230000001054 cortical effect Effects 0.000 description 1
- 230000007423 decrease Effects 0.000 description 1
- 229920006238 degradable plastic Polymers 0.000 description 1
- 239000004053 dental implant Substances 0.000 description 1
- 230000004069 differentiation Effects 0.000 description 1
- 230000006806 disease prevention Effects 0.000 description 1
- 210000001705 ectoderm cell Anatomy 0.000 description 1
- 229940126864 fibroblast growth factor Drugs 0.000 description 1
- 239000000945 filler Substances 0.000 description 1
- 210000001035 gastrointestinal tract Anatomy 0.000 description 1
- 210000001654 germ layer Anatomy 0.000 description 1
- 210000004907 gland Anatomy 0.000 description 1
- 238000005984 hydrogenation reaction Methods 0.000 description 1
- 230000002163 immunogen Effects 0.000 description 1
- 238000005470 impregnation Methods 0.000 description 1
- 230000002458 infectious effect Effects 0.000 description 1
- 230000008595 infiltration Effects 0.000 description 1
- 238000001764 infiltration Methods 0.000 description 1
- 239000003999 initiator Substances 0.000 description 1
- 208000014674 injury Diseases 0.000 description 1
- 230000003993 interaction Effects 0.000 description 1
- 210000003041 ligament Anatomy 0.000 description 1
- 230000007774 longterm Effects 0.000 description 1
- 238000012423 maintenance Methods 0.000 description 1
- 210000001161 mammalian embryo Anatomy 0.000 description 1
- 210000002050 maxilla Anatomy 0.000 description 1
- 230000005541 medical transmission Effects 0.000 description 1
- 239000000203 mixture Substances 0.000 description 1
- 210000000663 muscle cell Anatomy 0.000 description 1
- 210000005036 nerve Anatomy 0.000 description 1
- 210000000653 nervous system Anatomy 0.000 description 1
- 230000007935 neutral effect Effects 0.000 description 1
- 210000004279 orbit Anatomy 0.000 description 1
- 210000000963 osteoblast Anatomy 0.000 description 1
- 230000000278 osteoconductive effect Effects 0.000 description 1
- 230000002188 osteogenic effect Effects 0.000 description 1
- 210000004197 pelvis Anatomy 0.000 description 1
- 230000035515 penetration Effects 0.000 description 1
- 229920001610 polycaprolactone Polymers 0.000 description 1
- 239000002243 precursor Substances 0.000 description 1
- 238000002360 preparation method Methods 0.000 description 1
- 230000002265 prevention Effects 0.000 description 1
- 230000002062 proliferating effect Effects 0.000 description 1
- 230000001737 promoting effect Effects 0.000 description 1
- 230000007115 recruitment Effects 0.000 description 1
- 239000012779 reinforcing material Substances 0.000 description 1
- 238000007634 remodeling Methods 0.000 description 1
- 229920005989 resin Polymers 0.000 description 1
- 239000011347 resin Substances 0.000 description 1
- 231100000241 scar Toxicity 0.000 description 1
- 210000000697 sensory organ Anatomy 0.000 description 1
- 238000000926 separation method Methods 0.000 description 1
- 230000007480 spreading Effects 0.000 description 1
- 238000003892 spreading Methods 0.000 description 1
- 230000006641 stabilisation Effects 0.000 description 1
- 238000011105 stabilization Methods 0.000 description 1
- 210000000130 stem cell Anatomy 0.000 description 1
- 230000001954 sterilising effect Effects 0.000 description 1
- 238000012414 sterilization procedure Methods 0.000 description 1
- 238000003860 storage Methods 0.000 description 1
- 238000006467 substitution reaction Methods 0.000 description 1
- 230000003746 surface roughness Effects 0.000 description 1
- 229920001169 thermoplastic Polymers 0.000 description 1
- 239000004416 thermosoftening plastic Substances 0.000 description 1
- 230000008467 tissue growth Effects 0.000 description 1
- 230000017423 tissue regeneration Effects 0.000 description 1
- 230000001131 transforming effect Effects 0.000 description 1
- 230000008733 trauma Effects 0.000 description 1
- 230000000472 traumatic effect Effects 0.000 description 1
- 230000002792 vascular Effects 0.000 description 1
- 230000007998 vessel formation Effects 0.000 description 1
- 239000011800 void material Substances 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods
- A61B17/56—Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor
- A61B17/58—Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor for osteosynthesis, e.g. bone plates, screws or setting implements
- A61B17/68—Internal fixation devices, including fasteners and spinal fixators, even if a part thereof projects from the skin
- A61B17/688—Internal fixation devices, including fasteners and spinal fixators, even if a part thereof projects from the skin for reattaching pieces of the skull
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods
- A61B17/56—Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor
- A61B17/58—Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor for osteosynthesis, e.g. bone plates, screws or setting implements
- A61B17/68—Internal fixation devices, including fasteners and spinal fixators, even if a part thereof projects from the skin
- A61B17/80—Cortical plates, i.e. bone plates; Instruments for holding or positioning cortical plates, or for compressing bones attached to cortical plates
- A61B17/8061—Cortical plates, i.e. bone plates; Instruments for holding or positioning cortical plates, or for compressing bones attached to cortical plates specially adapted for particular bones
- A61B17/8066—Cortical plates, i.e. bone plates; Instruments for holding or positioning cortical plates, or for compressing bones attached to cortical plates specially adapted for particular bones for pelvic reconstruction
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods
- A61B17/56—Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor
- A61B17/58—Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor for osteosynthesis, e.g. bone plates, screws or setting implements
- A61B17/68—Internal fixation devices, including fasteners and spinal fixators, even if a part thereof projects from the skin
- A61B17/80—Cortical plates, i.e. bone plates; Instruments for holding or positioning cortical plates, or for compressing bones attached to cortical plates
- A61B17/8085—Cortical plates, i.e. bone plates; Instruments for holding or positioning cortical plates, or for compressing bones attached to cortical plates with pliable or malleable elements or having a mesh-like structure, e.g. small strips
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/28—Bones
- A61F2/2803—Bones for mandibular reconstruction
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/28—Bones
- A61F2/2846—Support means for bone substitute or for bone graft implants, e.g. membranes or plates for covering bone defects
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/28—Bones
- A61F2/2875—Skull or cranium
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
- A61L31/005—Ingredients of undetermined constitution or reaction products thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
- A61L31/14—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
- A61L31/148—Materials at least partially resorbable by the body
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
- A61L31/14—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
- A61L31/16—Biologically active materials, e.g. therapeutic substances
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
- A61L31/14—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
- A61L31/18—Materials at least partially X-ray or laser opaque
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods
- A61B17/04—Surgical instruments, devices or methods for suturing wounds; Holders or packages for needles or suture materials
- A61B17/06—Needles ; Sutures; Needle-suture combinations; Holders or packages for needles or suture materials
- A61B17/06166—Sutures
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods
- A61B17/064—Surgical staples, i.e. penetrating the tissue
- A61B17/0642—Surgical staples, i.e. penetrating the tissue for bones, e.g. for osteosynthesis or connecting tendon to bone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods
- A61B17/08—Wound clamps or clips, i.e. not or only partly penetrating the tissue ; Devices for bringing together the edges of a wound
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods
- A61B17/56—Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor
- A61B17/58—Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor for osteosynthesis, e.g. bone plates, screws or setting implements
- A61B17/68—Internal fixation devices, including fasteners and spinal fixators, even if a part thereof projects from the skin
- A61B17/80—Cortical plates, i.e. bone plates; Instruments for holding or positioning cortical plates, or for compressing bones attached to cortical plates
- A61B17/8061—Cortical plates, i.e. bone plates; Instruments for holding or positioning cortical plates, or for compressing bones attached to cortical plates specially adapted for particular bones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods
- A61B17/56—Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor
- A61B17/58—Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor for osteosynthesis, e.g. bone plates, screws or setting implements
- A61B17/68—Internal fixation devices, including fasteners and spinal fixators, even if a part thereof projects from the skin
- A61B17/80—Cortical plates, i.e. bone plates; Instruments for holding or positioning cortical plates, or for compressing bones attached to cortical plates
- A61B17/8061—Cortical plates, i.e. bone plates; Instruments for holding or positioning cortical plates, or for compressing bones attached to cortical plates specially adapted for particular bones
- A61B17/8071—Cortical plates, i.e. bone plates; Instruments for holding or positioning cortical plates, or for compressing bones attached to cortical plates specially adapted for particular bones for the jaw
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods
- A61B2017/00004—(bio)absorbable, (bio)resorbable or resorptive
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods
- A61B17/064—Surgical staples, i.e. penetrating the tissue
- A61B2017/0647—Surgical staples, i.e. penetrating the tissue having one single leg, e.g. tacks
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods
- A61B17/064—Surgical staples, i.e. penetrating the tissue
- A61B2017/0647—Surgical staples, i.e. penetrating the tissue having one single leg, e.g. tacks
- A61B2017/0648—Surgical staples, i.e. penetrating the tissue having one single leg, e.g. tacks threaded, e.g. tacks with a screw thread
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61C—DENTISTRY; APPARATUS OR METHODS FOR ORAL OR DENTAL HYGIENE
- A61C8/00—Means to be fixed to the jaw-bone for consolidating natural teeth or for fixing dental prostheses thereon; Dental implants; Implanting tools
- A61C8/0003—Not used, see subgroups
- A61C8/0004—Consolidating natural teeth
- A61C8/0006—Periodontal tissue or bone regeneration
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/0077—Special surfaces of prostheses, e.g. for improving ingrowth
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/28—Bones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/30—Joints
- A61F2/30767—Special external or bone-contacting surface, e.g. coating for improving bone ingrowth
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/28—Bones
- A61F2002/2817—Bone stimulation by chemical reactions or by osteogenic or biological products for enhancing ossification, e.g. by bone morphogenetic or morphogenic proteins [BMP] or by transforming growth factors [TGF]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/28—Bones
- A61F2002/2835—Bone graft implants for filling a bony defect or an endoprosthesis cavity, e.g. by synthetic material or biological material
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/28—Bones
- A61F2/2875—Skull or cranium
- A61F2002/2878—Skull or cranium for orbital repair
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/28—Bones
- A61F2/2875—Skull or cranium
- A61F2002/2889—Maxillary, premaxillary or molar implants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/30—Joints
- A61F2002/30001—Additional features of subject-matter classified in A61F2/28, A61F2/30 and subgroups thereof
- A61F2002/30003—Material related properties of the prosthesis or of a coating on the prosthesis
- A61F2002/3006—Properties of materials and coating materials
- A61F2002/30062—(bio)absorbable, biodegradable, bioerodable, (bio)resorbable, resorptive
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/30—Joints
- A61F2002/30001—Additional features of subject-matter classified in A61F2/28, A61F2/30 and subgroups thereof
- A61F2002/30108—Shapes
- A61F2002/30199—Three-dimensional shapes
- A61F2002/30224—Three-dimensional shapes cylindrical
- A61F2002/30235—Three-dimensional shapes cylindrical tubular, e.g. sleeves
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/30—Joints
- A61F2002/30001—Additional features of subject-matter classified in A61F2/28, A61F2/30 and subgroups thereof
- A61F2002/30316—The prosthesis having different structural features at different locations within the same prosthesis; Connections between prosthetic parts; Special structural features of bone or joint prostheses not otherwise provided for
- A61F2002/30329—Connections or couplings between prosthetic parts, e.g. between modular parts; Connecting elements
- A61F2002/30428—Connections or couplings between prosthetic parts, e.g. between modular parts; Connecting elements made by inserting a protrusion into a slot
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/30—Joints
- A61F2/30767—Special external or bone-contacting surface, e.g. coating for improving bone ingrowth
- A61F2/30771—Special external or bone-contacting surface, e.g. coating for improving bone ingrowth applied in original prostheses, e.g. holes or grooves
- A61F2002/30772—Apertures or holes, e.g. of circular cross section
- A61F2002/30784—Plurality of holes
- A61F2002/30785—Plurality of holes parallel
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/30—Joints
- A61F2/30767—Special external or bone-contacting surface, e.g. coating for improving bone ingrowth
- A61F2/30771—Special external or bone-contacting surface, e.g. coating for improving bone ingrowth applied in original prostheses, e.g. holes or grooves
- A61F2002/30772—Apertures or holes, e.g. of circular cross section
- A61F2002/30784—Plurality of holes
- A61F2002/30787—Plurality of holes inclined obliquely with respect to each other
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/30—Joints
- A61F2/46—Special tools for implanting artificial joints
- A61F2/4644—Preparation of bone graft, bone plugs or bone dowels, e.g. grinding or milling bone material
- A61F2002/4649—Bone graft or bone dowel harvest sites
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2210/00—Particular material properties of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
- A61F2210/0004—Particular material properties of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof bioabsorbable
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2220/00—Fixations or connections for prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
- A61F2220/0025—Connections or couplings between prosthetic parts, e.g. between modular parts; Connecting elements
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2230/00—Geometry of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
- A61F2230/0063—Three-dimensional shapes
- A61F2230/0069—Three-dimensional shapes cylindrical
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
- A61L2300/412—Tissue-regenerating or healing or proliferative agents
Landscapes
- Health & Medical Sciences (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Life Sciences & Earth Sciences (AREA)
- Heart & Thoracic Surgery (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Surgery (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Vascular Medicine (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Epidemiology (AREA)
- Transplantation (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Neurology (AREA)
- Medical Informatics (AREA)
- Cardiology (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Neurosurgery (AREA)
- Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Plastic & Reconstructive Surgery (AREA)
- Medicinal Chemistry (AREA)
- Physics & Mathematics (AREA)
- Optics & Photonics (AREA)
- Prostheses (AREA)
- Materials For Medical Uses (AREA)
- Separation Using Semi-Permeable Membranes (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US8100698P | 1998-04-07 | 1998-04-07 | |
| US81006P | 1998-04-07 | ||
| PCT/US1999/007655 WO1999051171A1 (en) | 1998-04-07 | 1999-04-07 | Membrane with tissue-guiding surface corrugations |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DE69923167D1 DE69923167D1 (de) | 2005-02-17 |
| DE69923167T2 true DE69923167T2 (de) | 2006-01-12 |
Family
ID=22161244
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE69923167T Expired - Fee Related DE69923167T2 (de) | 1998-04-07 | 1999-04-07 | Membran mit gewellter Oberfläche zur Führung des Gewebes |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US6391059B1 (enExample) |
| EP (1) | EP1069874B1 (enExample) |
| JP (1) | JP2002510530A (enExample) |
| AT (1) | ATE286692T1 (enExample) |
| AU (1) | AU761058B2 (enExample) |
| CA (1) | CA2327789C (enExample) |
| DE (1) | DE69923167T2 (enExample) |
| WO (1) | WO1999051171A1 (enExample) |
Families Citing this family (80)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE10237531A1 (de) * | 2002-08-16 | 2004-02-26 | Tutogen Medical Gmbh | Implantat |
| EP1233714B1 (en) * | 1999-11-30 | 2012-02-01 | Linvatec Biomaterials Ltd. | Bioabsorbable, osteopromoting fixation plate |
| WO2001041661A1 (en) | 1999-12-09 | 2001-06-14 | Macropore | Partially resorbable connective tissue distraction devices and techniques |
| US7592017B2 (en) * | 2000-03-10 | 2009-09-22 | Mast Biosurgery Ag | Resorbable thin membranes |
| WO2002009597A2 (en) * | 2000-08-01 | 2002-02-07 | Regeneration Technologies, Inc. | Diaphysial cortical dowel |
| US6534693B2 (en) * | 2000-11-06 | 2003-03-18 | Afmedica, Inc. | Surgically implanted devices having reduced scar tissue formation |
| US6692498B1 (en) | 2000-11-27 | 2004-02-17 | Linvatec Corporation | Bioabsorbable, osteopromoting fixation plate |
| FR2819715B1 (fr) | 2001-01-25 | 2004-01-02 | Cousin Biotech | Dispositif de reparation osseuse |
| US20050261780A1 (en) * | 2001-06-08 | 2005-11-24 | Harri Heino | Form-fitting bioabsorbable mesh implant |
| DK1545389T3 (da) * | 2002-07-31 | 2020-07-20 | Mast Biosurgery Ag | Indretning til forebyggelse af adhæsioner mellem et implantat og omgivende væv |
| US8048444B2 (en) * | 2002-07-31 | 2011-11-01 | Mast Biosurgery Ag | Apparatus and method for preventing adhesions between an implant and surrounding tissues |
| DE10238306B4 (de) * | 2002-08-21 | 2005-03-24 | Biedermann Motech Gmbh | Verfahren zum Herstellen eines rohrförmigen Platzhalters und Platzhalter |
| US7704520B1 (en) | 2002-09-10 | 2010-04-27 | Mast Biosurgery Ag | Methods of promoting enhanced healing of tissues after cardiac surgery |
| US20060083767A1 (en) * | 2003-02-27 | 2006-04-20 | Kai Deusch | Surgical prosthesis having biodegradable and nonbiodegradable regions |
| KR20100102753A (ko) | 2003-04-16 | 2010-09-24 | 포렉스 서지칼, 인크. | 두개안면 임플란트 |
| US8298292B2 (en) | 2003-04-16 | 2012-10-30 | Howmedica Osteonics Corp. | Craniofacial implant |
| WO2004098457A1 (en) * | 2003-04-30 | 2004-11-18 | Therics, Inc. | Bone void filler and method of manufacture |
| CA2529954A1 (en) | 2003-06-18 | 2005-02-10 | Macropore Biosurgery, Inc. | Methods of using adipose tissue-derived cells in augmenting autologous fat transfer |
| CA2530630A1 (en) | 2003-06-25 | 2005-02-10 | Macropore Biosurgery Inc. | Systems and methods for separating and concentrating regenerative cells from tissue |
| US7931695B2 (en) * | 2003-07-15 | 2011-04-26 | Kensey Nash Corporation | Compliant osteosynthesis fixation plate |
| RU2261681C2 (ru) * | 2003-08-19 | 2005-10-10 | ГУ "Российский научно-исследовательский институт травматологии и ортопедии им. Р.Р. Вредена | Пластина для остеосинтеза переломов эндопротезированной кости |
| US20100266663A1 (en) * | 2003-09-10 | 2010-10-21 | Calhoun Christopher J | Tissue-treating implantable compositions |
| MXPA06003088A (es) | 2003-09-17 | 2006-06-20 | Macropore Biosurgery Inc | Metodos para usar celulas regenerativas en el tratamiento de enfermedades vasculares perifericas y trastornos relacionados. |
| ATE361724T1 (de) * | 2004-01-23 | 2007-06-15 | Depuy Orthopaedics Inc | Satz von knochenschutzausrüstungen |
| EP1743021B1 (en) | 2004-03-19 | 2014-03-26 | Cytori Therapeutics, Inc. | Method of preparing regenerative cells on a cell carrier and cell carrier containment device |
| US20050216008A1 (en) * | 2004-03-24 | 2005-09-29 | Zwirnmann Ralph F | Bone fixation implants |
| US7887587B2 (en) * | 2004-06-04 | 2011-02-15 | Synthes Usa, Llc | Soft tissue spacer |
| EP2332555A3 (en) | 2004-07-01 | 2011-06-29 | Cytori Therapeutics, Inc. | Methods of using regenerative cells to promote wound healing |
| EP1778293B1 (en) | 2004-07-01 | 2015-04-22 | Cytori Therapeutics, Inc. | Methods of using regenerative cells in the treatment of musculoskeletal disorders |
| US20060029633A1 (en) * | 2004-08-03 | 2006-02-09 | Arthrotek, Inc | Biological patch for use in medical procedures |
| EP1776065B1 (en) * | 2004-08-13 | 2012-02-15 | Mast Biosurgery AG | Surgical prosthesis having biodegradable and nonbiodegradable regions |
| US20080091277A1 (en) * | 2004-08-13 | 2008-04-17 | Kai Deusch | Surgical prosthesis having biodegradable and nonbiodegradable regions |
| CA2578113A1 (en) | 2004-08-30 | 2006-03-09 | Spineovations, Inc. | Method of treating spinal internal disk derangement |
| US8127770B2 (en) * | 2004-08-30 | 2012-03-06 | Spineovations, Inc. | Method of using an implant for treament of ligaments and tendons |
| ITUD20040213A1 (it) * | 2004-11-12 | 2005-02-12 | Oralplant Srl | Dispositivo medico per la rigenerazione e |
| AU2005332046B2 (en) | 2005-05-25 | 2013-05-16 | Cytori Therapeutics, Inc. | Methods of using adipose tissue-derived cells in the treatment of cardiovascular conditions |
| US20070038299A1 (en) * | 2005-08-12 | 2007-02-15 | Arthrotek, Inc | Multilayer microperforated implant |
| US20080119878A1 (en) * | 2005-08-12 | 2008-05-22 | Kai Deusch | Surgical prosthesis having biodegradable and nonbiodegradable regions |
| WO2007047420A2 (en) | 2005-10-13 | 2007-04-26 | Synthes (U.S.A.) | Drug-impregnated encasement |
| US8690957B2 (en) | 2005-12-21 | 2014-04-08 | Warsaw Orthopedic, Inc. | Bone graft composition, method and implant |
| US12171904B2 (en) | 2006-10-30 | 2024-12-24 | Trs Holdings Llc | Mineral coated scaffolds |
| US20080299172A1 (en) * | 2007-06-04 | 2008-12-04 | Stuart Young | Tissue repair implant |
| US20110054408A1 (en) * | 2007-07-10 | 2011-03-03 | Guobao Wei | Delivery systems, devices, tools, and methods of use |
| US20090024147A1 (en) * | 2007-07-18 | 2009-01-22 | Ralph James D | Implantable mesh for musculoskeletal trauma, orthopedic reconstruction and soft tissue repair |
| EP2222349B1 (en) * | 2007-12-17 | 2014-03-12 | Anna Love | Soft tissue filler |
| US20100004700A1 (en) * | 2008-03-05 | 2010-01-07 | Neville Alleyne | Method of treating tissue with a suspenson of tricalcium hydroxyapatite microspheres |
| US8469961B2 (en) * | 2008-03-05 | 2013-06-25 | Neville Alleyne | Methods and compositions for minimally invasive capsular augmentation of canine coxofemoral joints |
| US20090259263A1 (en) | 2008-04-11 | 2009-10-15 | Biomet Microfixation, Inc. | Apparatus and methods of fixating bone |
| US8962006B2 (en) | 2008-11-07 | 2015-02-24 | Sofradim Production | Composite mesh including a 3D mesh and a non porous film of oxidized cellulose from bacterial cellulose origin |
| EP2349075A2 (en) * | 2008-11-07 | 2011-08-03 | Sofradim Production | Medical device including a bacterial cellulose sheet, perforated or microperforated as a mesh |
| WO2010060090A1 (en) * | 2008-11-24 | 2010-05-27 | Georgia Tech Research Corporation | Systems and methods to affect anatomical structures |
| US8500776B2 (en) | 2010-02-08 | 2013-08-06 | Covidien Lp | Vacuum patch for rapid wound closure |
| WO2012118843A1 (en) * | 2011-02-28 | 2012-09-07 | Tissue Regeneration Systems, Inc. | Modular tissue scaffolds |
| US20120244498A1 (en) * | 2011-03-23 | 2012-09-27 | Zimmer Dental, Inc. | Formable resorbable biomaterial interface for dental implant devices |
| US20120253339A1 (en) * | 2011-03-31 | 2012-10-04 | Tyco Healthcare Group Lp | Radio frequency-based surgical implant fixation apparatus |
| TWI590843B (zh) * | 2011-12-28 | 2017-07-11 | 信迪思有限公司 | 膜及其製造方法 |
| KR101405839B1 (ko) | 2012-08-01 | 2014-06-13 | 경희대학교 산학협력단 | 치조골 재생용 차폐막 |
| US9949837B2 (en) | 2013-03-07 | 2018-04-24 | Howmedica Osteonics Corp. | Partially porous bone implant keel |
| WO2014179720A1 (en) | 2013-05-02 | 2014-11-06 | University Of South Florida | Implantable sonic windows |
| US9580678B2 (en) | 2013-06-21 | 2017-02-28 | The Regents Of The University Of California | Microfluidic tumor tissue dissociation device |
| BR112015032045B1 (pt) | 2013-06-21 | 2020-06-09 | Depuy Synthes Products Inc | corpo flexível, método para formar um filme multicamadas para uso em combinação com um dispositivo médico implantável, sistema de armazenamento de filme e sistema para tratamento ortopédico |
| EP3042629B1 (en) * | 2013-09-02 | 2021-02-17 | Fukushima Medical University | Porous plate suitable for medical use and production method for porous plate suitable for medical use |
| KR101355598B1 (ko) | 2013-10-11 | 2014-02-04 | (주)이트리온홀딩스 | 안와벽 재건용 3차원 입체구조 임플란트 |
| US10076372B2 (en) | 2014-02-21 | 2018-09-18 | Jeko Metodiev Madjarov | Bone fixation implants and methods |
| EP3148598B1 (en) | 2014-05-30 | 2018-11-07 | Sofradim Production | Implant comprising oxidized cellulose and method for preparing such an implant |
| US20150366668A1 (en) * | 2014-06-23 | 2015-12-24 | Community Blood Center | Cellular-scale surface modification for increased osteogenic protein expression |
| EP3137058B1 (en) | 2015-01-16 | 2018-09-05 | SpineOvations, Inc. | Method of treating spinal disk |
| DE102015102597A1 (de) * | 2015-02-24 | 2016-08-25 | botiss biomaterials GmbH | Implantat zum Überdecken von Knochendefekten im Kieferbereich sowie Verfahren zu dessen Herstellung |
| EP3294222B1 (de) * | 2015-05-08 | 2020-12-16 | Reoss GmbH | Vorrichtung zur abdeckung und/oder rekonstruktion einer knochendefektstelle; verfahren zur herstellung eines aufsatzes einer abdeckung für eine knochendefekstelle |
| US10722540B1 (en) | 2016-02-01 | 2020-07-28 | The Regents Of The University Of California | Microfluidic device and method for shear stress-induced transformation of cells |
| CN115993462A (zh) | 2016-06-08 | 2023-04-21 | 加利福尼亚大学董事会 | 用于处理组织和细胞的方法和装置 |
| US11497608B2 (en) | 2017-02-06 | 2022-11-15 | DePuy Synthes Products, Inc. | Bendable graft containment cage |
| CN107374785B (zh) * | 2017-08-02 | 2019-04-05 | 吉林大学 | 一种眶壁爆裂性骨折钛网的预制作方法 |
| US10499966B2 (en) | 2017-10-24 | 2019-12-10 | DePuy Synthes Products, Inc. | Bone fixation system including an implant having a plate portion and a mesh portion |
| KR102888976B1 (ko) * | 2018-04-12 | 2025-12-04 | 옥소젠 코포레이션 | 사전 제작 부착점을 가지는 조직 이식편 |
| ES3047749T3 (en) * | 2020-05-29 | 2025-12-04 | Mat Nv | Implant for correcting a defect of a bone structure with navigation fiducials |
| US20220015872A1 (en) * | 2020-07-14 | 2022-01-20 | Flavio Sadamo Micima | Apparatus and method for rehabilitation of gum architecture |
| WO2024064656A2 (en) * | 2022-09-19 | 2024-03-28 | The Regents Of The University Of Michigan | Methods, devices, and systems for treating bone defects |
| WO2024250012A2 (en) | 2023-06-02 | 2024-12-05 | 33 Medical, Inc. | Compositions for treatment of discogenic pain, and processes for making and using the same |
| WO2025083466A1 (en) * | 2023-10-20 | 2025-04-24 | Stryker European Operations Limited | Orbital implant |
Family Cites Families (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3962153A (en) | 1970-05-21 | 1976-06-08 | W. L. Gore & Associates, Inc. | Very highly stretched polytetrafluoroethylene and process therefor |
| US4932973A (en) | 1983-09-30 | 1990-06-12 | El Gendler | Cartilage and bone induction by artificially perforated organic bone matrix |
| US5222987A (en) * | 1989-04-12 | 1993-06-29 | Imperial Chemical Industries Plc | Composite material for use in a prosthetic device |
| IT1248934B (it) | 1990-06-01 | 1995-02-11 | Fidia Spa | Membrane forate biocompatibili,processi per la loro preparazione,loro impiego come supporto per la crescita in vitro di cellule epiteliali, pelli artificiali cosi' ottenute e loro impiego nei trapianti di pelle |
| DE69120177T2 (de) * | 1990-09-10 | 1996-10-10 | Synthes Ag | Membran für Knochenregenerierung |
| ES2076467T3 (es) | 1990-10-31 | 1995-11-01 | El Gendler | Membranas flexibles producidas con materia de hueso organica para la reparacion y reconstruccion de partes del esqueleto. |
| US5348788A (en) * | 1991-01-30 | 1994-09-20 | Interpore Orthopaedics, Inc. | Mesh sheet with microscopic projections and holes |
| DE9115341U1 (de) * | 1991-12-11 | 1992-02-20 | Merten, Hans Albert, Dr.med. Dr.med.dent., 3400 Göttingen | Stützgitter zur Aufnahme von partikulären Knochenersatzmaterialien |
| US5346492A (en) | 1992-03-30 | 1994-09-13 | Timesh, Inc. | Perforated metallic panels and strips for internal fixation of bone fractures and for reconstructive surgery |
| DE4313192C1 (de) * | 1993-04-22 | 1994-09-15 | Kirsch Axel | Manschette zur Heilbeschleunigung von Knochendefekten |
| US5380328A (en) * | 1993-08-09 | 1995-01-10 | Timesh, Inc. | Composite perforated implant structures |
| US6113623A (en) * | 1994-04-20 | 2000-09-05 | Cabinet Beau De Lomenie | Prosthetic device and method for eventration repair |
| FR2720266B1 (fr) * | 1994-05-27 | 1996-12-20 | Cogent Sarl | Tissu prothétique. |
| US5919234A (en) * | 1996-08-19 | 1999-07-06 | Macropore, Inc. | Resorbable, macro-porous, non-collapsing and flexible membrane barrier for skeletal repair and regeneration |
| US5980540A (en) * | 1997-04-11 | 1999-11-09 | Kinamed, Inc. | Perforated cover for covering spaces in the cranium and conforming to the shape of the cranium |
| DE19746396A1 (de) * | 1997-10-21 | 1999-05-06 | Howmedica Leibinger Gmbh & Co | Gitter für die Fixierung von Knochenteilen oder für die Überbrückung von Knochenfehlstellen |
-
1999
- 1999-04-07 US US09/673,164 patent/US6391059B1/en not_active Expired - Fee Related
- 1999-04-07 DE DE69923167T patent/DE69923167T2/de not_active Expired - Fee Related
- 1999-04-07 AT AT99916479T patent/ATE286692T1/de not_active IP Right Cessation
- 1999-04-07 CA CA002327789A patent/CA2327789C/en not_active Expired - Fee Related
- 1999-04-07 WO PCT/US1999/007655 patent/WO1999051171A1/en not_active Ceased
- 1999-04-07 AU AU34791/99A patent/AU761058B2/en not_active Ceased
- 1999-04-07 EP EP99916479A patent/EP1069874B1/en not_active Expired - Lifetime
- 1999-04-07 JP JP2000541947A patent/JP2002510530A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| JP2002510530A (ja) | 2002-04-09 |
| EP1069874A4 (en) | 2003-03-19 |
| EP1069874A1 (en) | 2001-01-24 |
| AU3479199A (en) | 1999-10-25 |
| EP1069874B1 (en) | 2005-01-12 |
| CA2327789A1 (en) | 1999-10-14 |
| ATE286692T1 (de) | 2005-01-15 |
| WO1999051171A1 (en) | 1999-10-14 |
| DE69923167D1 (de) | 2005-02-17 |
| AU761058B2 (en) | 2003-05-29 |
| CA2327789C (en) | 2007-09-04 |
| US6391059B1 (en) | 2002-05-21 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| DE69923167T2 (de) | Membran mit gewellter Oberfläche zur Führung des Gewebes | |
| US6712851B1 (en) | Resorbable, macro-porous non-collapsing and flexible membrane barrier for skeletal repair and regeneration | |
| EP2108333B1 (de) | Implantat zur Implantation in Knochengewebe oder in durch Knochenersatzmaterial ergänztem Knochengewebe | |
| DE68913556T2 (de) | Chirurgische grenzschicht. | |
| US5919234A (en) | Resorbable, macro-porous, non-collapsing and flexible membrane barrier for skeletal repair and regeneration | |
| DE2203242C3 (de) | Prothese zum Ersatz einer beschädigten oder degenerierten Bandscheibe und Verfahren zu ihrer Herstellung | |
| DE69923696T2 (de) | Bioabsorbierbarer schichtverbundwerkstoff für die gesteuerte knochengewebsgeneration | |
| EP1411997B1 (de) | Textiles implantat mit monofilen polyvinylfluorid-fäden | |
| DE69018457T2 (de) | Gegenstände zur behandlung von periodontitis und knochendefekten. | |
| EP2062548B1 (de) | Medizinische Membranen zur Knochenregeneration | |
| EP0018496A1 (de) | Chirurgisches Netzwerk | |
| DE8804334U1 (de) | Medizinische Vorrichtung | |
| WO2003082160A1 (de) | Chirurgisches implantat | |
| EP2648647A1 (de) | Verbesserte distraktionsmembran | |
| DE2502884A1 (de) | Mittel zur biologischen implantation von knochen- und gelenkersatz | |
| DE68906856T2 (de) | Perkutanes Implantat. | |
| EP4274515B1 (de) | Mehrteiliges implantat mit stützelement und funktionselement | |
| EP3541438B1 (de) | Implantat und ein kit zum behandeln eines knochendefekts | |
| DE69736182T2 (de) | Biologisch abbaubare, makroporöse, nichtkollabierende und biegsame membransperre zur skelett-wiederherstellung und -regenerierung | |
| DE102010023794A1 (de) | Medizinisches, insbesondere zahnmedizinisches Substrat | |
| AU752357B2 (en) | Resorbable, macro-porous, non-collapsing and flexible membrane barrier for skeletal repair and regeneration |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 8364 | No opposition during term of opposition | ||
| 8339 | Ceased/non-payment of the annual fee |