DE69915977D1 - Neuartige Heparin bindende Peptide - Google Patents

Neuartige Heparin bindende Peptide

Info

Publication number
DE69915977D1
DE69915977D1 DE69915977T DE69915977T DE69915977D1 DE 69915977 D1 DE69915977 D1 DE 69915977D1 DE 69915977 T DE69915977 T DE 69915977T DE 69915977 T DE69915977 T DE 69915977T DE 69915977 D1 DE69915977 D1 DE 69915977D1
Authority
DE
Germany
Prior art keywords
heparin
binding peptides
present
heparin binding
exacerbation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69915977T
Other languages
English (en)
Inventor
Robert B Harris
Michael Sobel
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
COMMW BIOTECHNOLOGIES Inc
Original Assignee
COMMW BIOTECHNOLOGIES Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by COMMW BIOTECHNOLOGIES Inc filed Critical COMMW BIOTECHNOLOGIES Inc
Application granted granted Critical
Publication of DE69915977D1 publication Critical patent/DE69915977D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/001—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof by chemical synthesis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Diabetes (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Hematology (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Endocrinology (AREA)
  • Obesity (AREA)
  • Emergency Medicine (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
DE69915977T 1998-10-06 1999-10-01 Neuartige Heparin bindende Peptide Expired - Lifetime DE69915977D1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US09/166,930 US6200955B1 (en) 1996-06-11 1998-10-06 Heparin binding peptides

Publications (1)

Publication Number Publication Date
DE69915977D1 true DE69915977D1 (de) 2004-05-06

Family

ID=22605258

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69915977T Expired - Lifetime DE69915977D1 (de) 1998-10-06 1999-10-01 Neuartige Heparin bindende Peptide

Country Status (6)

Country Link
US (2) US6200955B1 (de)
EP (1) EP0999219B1 (de)
JP (1) JP3472513B2 (de)
AT (1) ATE263187T1 (de)
CA (1) CA2285151A1 (de)
DE (1) DE69915977D1 (de)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1174506A1 (de) * 2000-06-28 2002-01-23 Stichting Dienst Landbouwkundig Onderzoek C-terminales Erns-Peptide und Analoge davon
FR2813080B1 (fr) 2000-08-17 2002-11-29 Stago Diagnostica Peptides anti-heparine
US7199102B2 (en) 2000-08-24 2007-04-03 The Regents Of The University Of California Orally administered peptides synergize statin activity
US6664230B1 (en) * 2000-08-24 2003-12-16 The Regents Of The University Of California Orally administered peptides to ameliorate atherosclerosis
US7723303B2 (en) 2000-08-24 2010-05-25 The Regents Of The University Of California Peptides and peptide mimetics to treat pathologies characterized by an inflammatory response
CA2371514C (en) * 2001-02-14 2006-10-31 Commonwealth Biotechnologies, Inc. Adsorption and removal of endotoxin from physiological fluids using cationic helix peptides
JP2007502112A (ja) * 2003-08-12 2007-02-08 ユニバーシティ オブ ユタ リサーチ ファウンデーション ヘパリン結合タンパク質：ヘパリン検出のためのセンサー
US7637895B2 (en) 2006-08-22 2009-12-29 Nalin David R System and device for medically treating an individual
JP2010502719A (ja) 2006-09-08 2010-01-28 ロード アイランド ホスピタル アルコール誘発性脳疾患の治療、予防および回復
BR122022001846B1 (pt) 2007-09-28 2022-12-27 Portola Pharmaceuticals, Inc. Uso de polipeptídeo de duas cadeias para preparo de medicamento para reduzir sangramento
WO2010117729A1 (en) 2009-03-30 2010-10-14 Portola Pharmaceuticals, Inc. Antidotes for factor xa inhibitors and methods of using the same
ES2605801T3 (es) 2009-07-15 2017-03-16 Portola Pharmaceuticals, Inc. Formulación de dosis unitaria de antídoto para inhibidores del factor Xa para su uso en la prevención de la hemorragia
TWI513466B (zh) 2010-01-20 2015-12-21 Boehringer Ingelheim Int 抗凝血劑解毒劑
GB201004101D0 (en) * 2010-03-12 2010-04-28 Carmeda Ab Immobilised biological entities
CN103476459A (zh) 2011-03-30 2013-12-25 勃林格殷格翰国际有限公司 抗凝血剂解毒剂
US8519189B2 (en) 2011-06-01 2013-08-27 University Of British Columbia Polymers for reversing heparin-based anticoagulation
AU2015268149B2 (en) 2014-05-26 2021-03-11 Academisch Ziekenhuis Leiden Prohemostatic proteins for the treatment of bleeding
CA2954475C (en) 2014-07-31 2023-05-16 Uab Research Foundation Apoe mimetic peptides and higher potency to clear plasma cholesterol

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
USH1509H (en) * 1989-06-09 1995-12-05 Eran; Harutyun Heparin enhanced process for separating antihemophilic factor (Factor VIII) and fibronectin from cryoprecipitate
CA2123912C (en) * 1991-11-19 2007-04-17 Roger Aston Muramyl compounds for treatment of septic shock
US5614494A (en) 1993-11-12 1997-03-25 University Of Michigan, The Board Of Regents Acting For And On Behalf Of Peptides for heparin and low molecular weight heparin anticoagulation reversal
US5877153A (en) * 1996-06-11 1999-03-02 Commonwealth Biotechnologies Inc. Heparin-binding peptides

Also Published As

Publication number Publication date
EP0999219B1 (de) 2004-03-31
US6200955B1 (en) 2001-03-13
CA2285151A1 (en) 2000-04-06
JP2000136202A (ja) 2000-05-16
EP0999219A3 (de) 2000-05-24
US6756206B2 (en) 2004-06-29
US20020164329A1 (en) 2002-11-07
ATE263187T1 (de) 2004-04-15
JP3472513B2 (ja) 2003-12-02
EP0999219A2 (de) 2000-05-10

Similar Documents

Publication Publication Date Title
DE69915977D1 (de) Neuartige Heparin bindende Peptide
DK0696326T5 (da) Anvendelse af NDV til fremstilling af et medikament til behandling af cancer
WO1999029729A3 (en) Antagonists of neuropilin receptor function and use thereof
PL323490A1 (en) Tetralinic compounds exibiting acitity against multgiple-drug refractoriness
FI961083A (fi) Rekombinentti-IL4-vasta-aineita, jotka ovat käyttökelpoisia IL-4-välitteisten häiriötilojen hoidossa
BR9913533A (pt) Processos para tratar hipertensão e composições para uso nos mesmos
DE69943042D1 (de) Herstellungsverfahren von dispergiermittel enthaltenden konzentrate mit hohem molekulargewicht
WO1997029199A3 (en) Prostate specific antigen peptides and uses thereof
DE69002024D1 (de) Bioaktive laktoferrin derivate.
AU4373197A (en) Recombinant single chain antibodies directed against the gp54 cancer marker, composition comprising same and use thereof
EA200400670A1 (ru) Фармацевтические композиции, содержащие 3,4-пропинопергидропурины, и их применение для блокирования нейронной передачи
PT929299E (pt) 1,2,3,4-tetra-hidro-2-dibenzofuranaminas e 2-aminociclo-hepta ¬b| benzofuranos substituidos
IT8919735A0 (it) Procedimento per la riduzione del cod da reflui industriali o urbani.
DE69005136T2 (de) Grundierungszusammensetzung.
IL143279A0 (en) Novel therapeutic application of low molecular weight heparin
DE59009464D1 (de) Vernetzte Triazinpolymerisate und ihre Verwendung als Vernetzungsmittel.
FR2705244B1 (fr) Culotte de sauvetage.
FR2683840B1 (fr) Glissiere de securite routiere.
DE9419943U1 (de) Geländer für Treppen, Brüstungen o.dgl.
FR2704425B1 (fr) Orthese pour le maintien de la cheville.
NO985550D0 (no) FremgangsmÕte for fremstilling av 2,2'-(1-metyl-1,2-etandiyliden)bis(hydrazinkarboksimidamid)
RU97100921A (ru) Антигипоксический комплекс
FR2719050B1 (fr) Composition destinée à la fabrication de surfaces de glissement, notamment de semelles de ski ou similaires.
FR2690176B1 (fr) Glissiere de securite routiere.
FR2717390B1 (fr) Compositions thérapeutiques à base de peptides capables d'inhiber la libération de pepsine.

Legal Events

Date Code Title Description
8332 No legal effect for de