ATE263187T1 - Neuartige heparin bindende peptide - Google Patents
Neuartige heparin bindende peptideInfo
- Publication number
- ATE263187T1 ATE263187T1 AT99119514T AT99119514T ATE263187T1 AT E263187 T1 ATE263187 T1 AT E263187T1 AT 99119514 T AT99119514 T AT 99119514T AT 99119514 T AT99119514 T AT 99119514T AT E263187 T1 ATE263187 T1 AT E263187T1
- Authority
- AT
- Austria
- Prior art keywords
- heparin
- present
- binding peptides
- exacerbation
- injury
- Prior art date
Links
- 102000004196 processed proteins & peptides Human genes 0.000 title abstract 3
- 108090000765 processed proteins & peptides Proteins 0.000 title abstract 3
- 229920000669 heparin Polymers 0.000 abstract 5
- HTTJABKRGRZYRN-UHFFFAOYSA-N Heparin Chemical compound OC1C(NC(=O)C)C(O)OC(COS(O)(=O)=O)C1OC1C(OS(O)(=O)=O)C(O)C(OC2C(C(OS(O)(=O)=O)C(OC3C(C(O)C(O)C(O3)C(O)=O)OS(O)(=O)=O)C(CO)O2)NS(O)(=O)=O)C(C(O)=O)O1 HTTJABKRGRZYRN-UHFFFAOYSA-N 0.000 abstract 4
- 229960002897 heparin Drugs 0.000 abstract 4
- 208000027418 Wounds and injury Diseases 0.000 abstract 2
- 230000002429 anti-coagulating effect Effects 0.000 abstract 2
- 230000006378 damage Effects 0.000 abstract 2
- 230000002939 deleterious effect Effects 0.000 abstract 2
- 230000000694 effects Effects 0.000 abstract 2
- 230000005713 exacerbation Effects 0.000 abstract 2
- 230000000004 hemodynamic effect Effects 0.000 abstract 2
- 208000014674 injury Diseases 0.000 abstract 2
- 230000002062 proliferating effect Effects 0.000 abstract 2
- 230000004865 vascular response Effects 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 1
- 229940079593 drug Drugs 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 239000002607 heparin antagonist Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/001—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof by chemical synthesis
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Public Health (AREA)
- Engineering & Computer Science (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Diabetes (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Gastroenterology & Hepatology (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Hematology (AREA)
- Epidemiology (AREA)
- Immunology (AREA)
- Emergency Medicine (AREA)
- Endocrinology (AREA)
- Obesity (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US09/166,930 US6200955B1 (en) | 1996-06-11 | 1998-10-06 | Heparin binding peptides |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE263187T1 true ATE263187T1 (de) | 2004-04-15 |
Family
ID=22605258
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT99119514T ATE263187T1 (de) | 1998-10-06 | 1999-10-01 | Neuartige heparin bindende peptide |
Country Status (6)
| Country | Link |
|---|---|
| US (2) | US6200955B1 (de) |
| EP (1) | EP0999219B1 (de) |
| JP (1) | JP3472513B2 (de) |
| AT (1) | ATE263187T1 (de) |
| CA (1) | CA2285151A1 (de) |
| DE (1) | DE69915977D1 (de) |
Families Citing this family (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1174506A1 (de) * | 2000-06-28 | 2002-01-23 | Stichting Dienst Landbouwkundig Onderzoek | C-terminales Erns-Peptide und Analoge davon |
| FR2813080B1 (fr) | 2000-08-17 | 2002-11-29 | Stago Diagnostica | Peptides anti-heparine |
| US7199102B2 (en) | 2000-08-24 | 2007-04-03 | The Regents Of The University Of California | Orally administered peptides synergize statin activity |
| US6664230B1 (en) * | 2000-08-24 | 2003-12-16 | The Regents Of The University Of California | Orally administered peptides to ameliorate atherosclerosis |
| US7723303B2 (en) | 2000-08-24 | 2010-05-25 | The Regents Of The University Of California | Peptides and peptide mimetics to treat pathologies characterized by an inflammatory response |
| CA2371514C (en) * | 2001-02-14 | 2006-10-31 | Commonwealth Biotechnologies, Inc. | Adsorption and removal of endotoxin from physiological fluids using cationic helix peptides |
| WO2005018552A2 (en) * | 2003-08-12 | 2005-03-03 | University Of Utah Research Foundation | Heparin binding proteins: sensors for heparin detection |
| US7579319B2 (en) | 2004-12-06 | 2009-08-25 | The Regents Of The University Of California | Methods for improving the structure and function of arterioles |
| US7637895B2 (en) | 2006-08-22 | 2009-12-29 | Nalin David R | System and device for medically treating an individual |
| KR20090066289A (ko) | 2006-09-08 | 2009-06-23 | 로드아일랜드하스피틀 | 알코올 유발성 뇌 질환의 치료, 예방 및 역행 |
| EP2193196B1 (de) | 2007-09-28 | 2016-07-13 | Portola Pharmaceuticals, Inc. | Gegenmittel für faktor-xa-hemmer und verwendungsverfahren dafür |
| LT3604510T (lt) | 2009-03-30 | 2025-07-10 | Alexion Pharmaceuticals, Inc. | Faktoriaus xa inhibitorius neutralizuojančios medžiagos ir jų naudojimo būdai |
| JP6163304B2 (ja) | 2009-07-15 | 2017-07-12 | ポートラ ファーマシューティカルズ， インコーポレイテッド | 第Ｘａ因子インヒビターの解毒剤の単位用量処方物およびその使用方法 |
| TWI513466B (zh) | 2010-01-20 | 2015-12-21 | Boehringer Ingelheim Int | 抗凝血劑解毒劑 |
| GB201004101D0 (en) | 2010-03-12 | 2010-04-28 | Carmeda Ab | Immobilised biological entities |
| PE20140964A1 (es) | 2011-03-30 | 2014-08-17 | Boehringer Ingelheim Int | Antidotos anticoagulantes |
| WO2012162789A1 (en) * | 2011-06-01 | 2012-12-06 | University Of British Columbia | Polymers for reversing heparin-based anticoagulation |
| MX378899B (es) | 2014-05-26 | 2025-03-10 | Academisch Ziekenhuis Leiden | Proteinas prohemostaticas para el tratamiento de hemorragias. |
| CA2954475C (en) | 2014-07-31 | 2023-05-16 | Uab Research Foundation | Apoe mimetic peptides and higher potency to clear plasma cholesterol |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| USH1509H (en) * | 1989-06-09 | 1995-12-05 | Eran; Harutyun | Heparin enhanced process for separating antihemophilic factor (Factor VIII) and fibronectin from cryoprecipitate |
| RU2139086C1 (ru) * | 1991-11-19 | 1999-10-10 | Закрытое акционерное общество "ПЕПТЕК" | Способ лечения септического шока и применение мурамиловых соединений |
| US5614494A (en) | 1993-11-12 | 1997-03-25 | University Of Michigan, The Board Of Regents Acting For And On Behalf Of | Peptides for heparin and low molecular weight heparin anticoagulation reversal |
| US5877153A (en) | 1996-06-11 | 1999-03-02 | Commonwealth Biotechnologies Inc. | Heparin-binding peptides |
-
1998
- 1998-10-06 US US09/166,930 patent/US6200955B1/en not_active Expired - Lifetime
-
1999
- 1999-10-01 EP EP99119514A patent/EP0999219B1/de not_active Expired - Lifetime
- 1999-10-01 AT AT99119514T patent/ATE263187T1/de not_active IP Right Cessation
- 1999-10-01 DE DE69915977T patent/DE69915977D1/de not_active Expired - Lifetime
- 1999-10-05 CA CA002285151A patent/CA2285151A1/en not_active Abandoned
- 1999-10-06 JP JP28518599A patent/JP3472513B2/ja not_active Expired - Fee Related
-
2001
- 2001-02-14 US US09/905,691 patent/US6756206B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| EP0999219A2 (de) | 2000-05-10 |
| EP0999219B1 (de) | 2004-03-31 |
| CA2285151A1 (en) | 2000-04-06 |
| US6200955B1 (en) | 2001-03-13 |
| US20020164329A1 (en) | 2002-11-07 |
| US6756206B2 (en) | 2004-06-29 |
| JP3472513B2 (ja) | 2003-12-02 |
| EP0999219A3 (de) | 2000-05-24 |
| DE69915977D1 (de) | 2004-05-06 |
| JP2000136202A (ja) | 2000-05-16 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |