ATE263187T1 - Neuartige heparin bindende peptide - Google Patents

Neuartige heparin bindende peptide

Info

Publication number
ATE263187T1
ATE263187T1 AT99119514T AT99119514T ATE263187T1 AT E263187 T1 ATE263187 T1 AT E263187T1 AT 99119514 T AT99119514 T AT 99119514T AT 99119514 T AT99119514 T AT 99119514T AT E263187 T1 ATE263187 T1 AT E263187T1
Authority
AT
Austria
Prior art keywords
heparin
present
binding peptides
exacerbation
injury
Prior art date
Application number
AT99119514T
Other languages
English (en)
Inventor
Robert B Harris
Michael Sobel
Original Assignee
Commw Biotechnologies Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Commw Biotechnologies Inc filed Critical Commw Biotechnologies Inc
Application granted granted Critical
Publication of ATE263187T1 publication Critical patent/ATE263187T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04Linear peptides containing only normal peptide links
    • C07K7/08Linear peptides containing only normal peptide links having 12 to 20 amino acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/04Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/001Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof by chemical synthesis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Diabetes (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Hematology (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Endocrinology (AREA)
  • Obesity (AREA)
  • Emergency Medicine (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
AT99119514T 1998-10-06 1999-10-01 Neuartige heparin bindende peptide ATE263187T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US09/166,930 US6200955B1 (en) 1996-06-11 1998-10-06 Heparin binding peptides

Publications (1)

Publication Number Publication Date
ATE263187T1 true ATE263187T1 (de) 2004-04-15

Family

ID=22605258

Family Applications (1)

Application Number Title Priority Date Filing Date
AT99119514T ATE263187T1 (de) 1998-10-06 1999-10-01 Neuartige heparin bindende peptide

Country Status (6)

Country Link
US (2) US6200955B1 (de)
EP (1) EP0999219B1 (de)
JP (1) JP3472513B2 (de)
AT (1) ATE263187T1 (de)
CA (1) CA2285151A1 (de)
DE (1) DE69915977D1 (de)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1174506A1 (de) * 2000-06-28 2002-01-23 Stichting Dienst Landbouwkundig Onderzoek C-terminales Erns-Peptide und Analoge davon
FR2813080B1 (fr) 2000-08-17 2002-11-29 Stago Diagnostica Peptides anti-heparine
US7723303B2 (en) 2000-08-24 2010-05-25 The Regents Of The University Of California Peptides and peptide mimetics to treat pathologies characterized by an inflammatory response
US6664230B1 (en) * 2000-08-24 2003-12-16 The Regents Of The University Of California Orally administered peptides to ameliorate atherosclerosis
US7199102B2 (en) 2000-08-24 2007-04-03 The Regents Of The University Of California Orally administered peptides synergize statin activity
CA2371514C (en) * 2001-02-14 2006-10-31 Commonwealth Biotechnologies, Inc. Adsorption and removal of endotoxin from physiological fluids using cationic helix peptides
CA2536504A1 (en) * 2003-08-12 2005-03-03 Glenn D. Prestwich Heparin binding proteins: sensors for heparin detection
US7637895B2 (en) 2006-08-22 2009-12-29 Nalin David R System and device for medically treating an individual
WO2008030604A2 (en) 2006-09-08 2008-03-13 Rhode Island Hospital Treatment, prevention, and reversal of alcohol-induced brain disease
US8268783B2 (en) 2007-09-28 2012-09-18 Portola Pharmaceuticals, Inc. Antidotes for factor Xa inhibitors and methods of using the same
DK2193196T3 (en) 2007-09-28 2016-11-07 Portola Pharm Inc Clinical profile of Factor Xa inhibitors, and methods of use thereof
CA2767858C (en) 2009-07-15 2019-02-12 Portola Pharmaceuticals, Inc. Unit dose formulation of antidotes for factor xa inhibitors and methods of using the same
TWI513466B (zh) 2010-01-20 2015-12-21 Boehringer Ingelheim Int 抗凝血劑解毒劑
GB201004101D0 (en) 2010-03-12 2010-04-28 Carmeda Ab Immobilised biological entities
PE20140964A1 (es) 2011-03-30 2014-08-17 Boehringer Ingelheim Int Antidotos anticoagulantes
US8519189B2 (en) 2011-06-01 2013-08-27 University Of British Columbia Polymers for reversing heparin-based anticoagulation
CN106536566A (zh) 2014-05-26 2017-03-22 莱顿教学医院 用于出血治疗的促止血蛋白
WO2016018665A1 (en) 2014-07-31 2016-02-04 Uab Research Foundation Apoe mimetic peptides and higher potency to clear plasma cholesterol

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
USH1509H (en) * 1989-06-09 1995-12-05 Eran; Harutyun Heparin enhanced process for separating antihemophilic factor (Factor VIII) and fibronectin from cryoprecipitate
EP0615522B1 (de) * 1991-11-19 1999-09-22 Peptech (Uk) Limited Muramylverbindungen zur behandlung von septischem schock
US5614494A (en) 1993-11-12 1997-03-25 University Of Michigan, The Board Of Regents Acting For And On Behalf Of Peptides for heparin and low molecular weight heparin anticoagulation reversal
US5877153A (en) * 1996-06-11 1999-03-02 Commonwealth Biotechnologies Inc. Heparin-binding peptides

Also Published As

Publication number Publication date
EP0999219B1 (de) 2004-03-31
JP2000136202A (ja) 2000-05-16
DE69915977D1 (de) 2004-05-06
EP0999219A2 (de) 2000-05-10
CA2285151A1 (en) 2000-04-06
US6200955B1 (en) 2001-03-13
JP3472513B2 (ja) 2003-12-02
US20020164329A1 (en) 2002-11-07
EP0999219A3 (de) 2000-05-24
US6756206B2 (en) 2004-06-29

Similar Documents

Publication Publication Date Title
ATE263187T1 (de) Neuartige heparin bindende peptide
DK0696326T3 (da) Anvendelse af NDV til fremstilling af et medikament til behandling af cancer
ES2184149T3 (es) Paclitaxeles 6-tio sustituidos.
TR200001218T2 (tr) İkameli karboksamidotiazoller, bunların üretimi ve bunları içeren farmasötik bileşimler.
CY1108610T1 (el) Πεπτιδια της il-2 και παραγωγα αυτων και χρηση αυτων ως θεραπευτικοι παραγοντες
IL125124A0 (en) Dimeric forms of the protein fapalpha and uses thereof
DK0842934T3 (da) 5-HT1F agonister
PL323490A1 (en) Tetralinic compounds exibiting acitity against multgiple-drug refractoriness
AU2001235006A1 (en) Prophylactic and therapeutic monoclonal antibodies
BR9913533A (pt) Processos para tratar hipertensão e composições para uso nos mesmos
ES2191075T3 (es) 8-arilalquil- y 8-arilheteroalquil-5,11-dihidro-6h-dipirido-(3,2-b:2',3'-e)(1,4)diazepinas y su uso en la prevencion o tratamiento de infecciones por hiv.
DE69614149D1 (de) Chinolinderivate als antimalariamittel
SE9802937D0 (sv) Novel compounds
DE69943042D1 (de) Herstellungsverfahren von dispergiermittel enthaltenden konzentrate mit hohem molekulargewicht
DE69002024D1 (de) Bioaktive laktoferrin derivate.
EA200400670A1 (ru) Фармацевтические композиции, содержащие 3,4-пропинопергидропурины, и их применение для блокирования нейронной передачи
TR200000005T2 (tr) Sıtmaya karşı ß-alkoksiakrilatlar.
NO20002408D0 (no) 5-HT1F antagonister
IT8919735A0 (it) Procedimento per la riduzione del cod da reflui industriali o urbani.
DE69005136D1 (de) Grundierungszusammensetzung.
AU1569700A (en) Novel therapeutic application of low molecular weight heparin
FR2705244B1 (fr) Culotte de sauvetage.
BR9710992A (pt) Derivados anticovulsivos úteis no tratamento de psorìase
DE59009464D1 (de) Vernetzte Triazinpolymerisate und ihre Verwendung als Vernetzungsmittel.
RU97100921A (ru) Антигипоксический комплекс

Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties