DE69915128D1 - 7-aryl-6(z)heptatriensäure retinamide als apoptose induzierende verbindungen und deren verwendung als antikrebsmittel - Google Patents
7-aryl-6(z)heptatriensäure retinamide als apoptose induzierende verbindungen und deren verwendung als antikrebsmittelInfo
- Publication number
- DE69915128D1 DE69915128D1 DE69915128T DE69915128T DE69915128D1 DE 69915128 D1 DE69915128 D1 DE 69915128D1 DE 69915128 T DE69915128 T DE 69915128T DE 69915128 T DE69915128 T DE 69915128T DE 69915128 D1 DE69915128 D1 DE 69915128D1
- Authority
- DE
- Germany
- Prior art keywords
- heptatric
- retinamide
- aryl
- acid
- apoptosis inducing
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C233/00—Carboxylic acid amides
- C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
- C07C233/16—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms
- C07C233/24—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by a carbon atom of a six-membered aromatic ring
- C07C233/29—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by a carbon atom of a six-membered aromatic ring having the carbon atom of the carboxamide group bound to an acyclic carbon atom of a carbon skeleton containing six-membered aromatic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C235/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms
- C07C235/02—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton
- C07C235/32—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton the carbon skeleton containing six-membered aromatic rings
- C07C235/38—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton the carbon skeleton containing six-membered aromatic rings having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a six-membered aromatic ring
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US11263598P | 1998-12-17 | 1998-12-17 | |
| PCT/EP1999/009780 WO2000035856A1 (en) | 1998-12-17 | 1999-12-10 | 7-aryl-6(z)heptatrienoic acid retinamides as apoptosis inducing compounds and their use as anti-cancer agents |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DE69915128D1 true DE69915128D1 (de) | 2004-04-01 |
Family
ID=22345024
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE69915128T Expired - Lifetime DE69915128D1 (de) | 1998-12-17 | 1999-12-10 | 7-aryl-6(z)heptatriensäure retinamide als apoptose induzierende verbindungen und deren verwendung als antikrebsmittel |
Country Status (16)
| Country | Link |
|---|---|
| US (1) | US6310247B1 (de) |
| EP (1) | EP1149067B1 (de) |
| JP (1) | JP2002532458A (de) |
| KR (1) | KR20020002364A (de) |
| CN (1) | CN1330630A (de) |
| AR (1) | AR021694A1 (de) |
| AT (1) | ATE260242T1 (de) |
| AU (1) | AU771761B2 (de) |
| CA (1) | CA2355714A1 (de) |
| DE (1) | DE69915128D1 (de) |
| PE (1) | PE20001350A1 (de) |
| TR (1) | TR200101749T2 (de) |
| TW (1) | TW455575B (de) |
| UY (1) | UY25861A1 (de) |
| WO (1) | WO2000035856A1 (de) |
| ZA (1) | ZA200104271B (de) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2003044535A1 (en) * | 2001-11-22 | 2003-05-30 | Mehmet Ozturk | Method, antigen and antibody for distinguishing viable and apoptotic cells |
| ES2304112B1 (es) | 2007-02-23 | 2009-08-13 | Universidad De Zaragoza | Uso de compuestos como inhibidores de la flavodoxina de helicobacter. |
| ES2304221B1 (es) | 2007-03-02 | 2009-09-11 | Universidad De Zaragoza | Composicion para el tratamiento de enfermedades infecciosas causadas por helicobacter. |
| ES2304220B1 (es) * | 2007-03-02 | 2009-09-11 | Universidad De Zaragoza | Composicion para el tratamiento de enfermedades infecciosas. |
| EP2239582A1 (de) * | 2009-04-09 | 2010-10-13 | Nederlandse Organisatie voor toegepast -natuurwetenschappelijk onderzoek TNO | Testsystem zur Bestimmung der Bindung an hydrophobe Arzneimittel |
| CN102304056B (zh) * | 2011-07-04 | 2013-12-11 | 浙江大学 | 3-甲基-4-芳基-3-烯-丁酰五氟苯胺衍生物及制备方法 |
| RU2505492C1 (ru) * | 2012-06-14 | 2014-01-27 | Федеральное государственное бюджетное образовательное учреждение высшего профессионального образования "Российский химико-технологический университет им. Д.И. Менделеева" (РХТУ им. Д.И. Менделеева") | Способ получения микрошариков из иттрий-алюмосиликатного стекла для радиотерапии |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5399757A (en) * | 1993-07-20 | 1995-03-21 | Ortho Pharmaceutical Corporation | Process for the preparation of N-(4-hydroxyphenyl)-retinamide |
| FR2719041B1 (fr) | 1994-04-26 | 1996-05-31 | Cird Galderma | Nouveaux composés polyéniques, compositions pharmaceutiques et cosmétiques les contenant et utilisations. |
| AU712187B2 (en) * | 1994-12-30 | 1999-10-28 | Ligand Pharmaceuticals Incorporated | Novel trienoic retinoid compounds and methods |
| US6083977A (en) * | 1994-12-30 | 2000-07-04 | Ligand Pharmaceuticals Incorporated | Trienoic retinoid compounds and methods |
-
1999
- 1999-12-10 JP JP2000588118A patent/JP2002532458A/ja active Pending
- 1999-12-10 TR TR2001/01749T patent/TR200101749T2/xx unknown
- 1999-12-10 DE DE69915128T patent/DE69915128D1/de not_active Expired - Lifetime
- 1999-12-10 AU AU19765/00A patent/AU771761B2/en not_active Ceased
- 1999-12-10 EP EP99963486A patent/EP1149067B1/de not_active Expired - Lifetime
- 1999-12-10 AT AT99963486T patent/ATE260242T1/de not_active IP Right Cessation
- 1999-12-10 KR KR1020017007571A patent/KR20020002364A/ko not_active Application Discontinuation
- 1999-12-10 CA CA002355714A patent/CA2355714A1/en not_active Abandoned
- 1999-12-10 WO PCT/EP1999/009780 patent/WO2000035856A1/en not_active Application Discontinuation
- 1999-12-10 CN CN99814574A patent/CN1330630A/zh active Pending
- 1999-12-14 US US09/460,911 patent/US6310247B1/en not_active Expired - Fee Related
- 1999-12-14 PE PE1999001250A patent/PE20001350A1/es not_active Application Discontinuation
- 1999-12-15 AR ARP990106419A patent/AR021694A1/es not_active Application Discontinuation
- 1999-12-17 UY UY25861A patent/UY25861A1/es unknown
- 1999-12-17 TW TW088122200A patent/TW455575B/zh not_active IP Right Cessation
-
2001
- 2001-05-24 ZA ZA200104271A patent/ZA200104271B/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| AU771761B2 (en) | 2004-04-01 |
| WO2000035856A1 (en) | 2000-06-22 |
| TW455575B (en) | 2001-09-21 |
| AR021694A1 (es) | 2002-07-31 |
| US6310247B1 (en) | 2001-10-30 |
| CA2355714A1 (en) | 2000-06-22 |
| AU1976500A (en) | 2000-07-03 |
| CN1330630A (zh) | 2002-01-09 |
| TR200101749T2 (tr) | 2001-10-22 |
| PE20001350A1 (es) | 2000-12-06 |
| EP1149067A1 (de) | 2001-10-31 |
| ATE260242T1 (de) | 2004-03-15 |
| KR20020002364A (ko) | 2002-01-09 |
| JP2002532458A (ja) | 2002-10-02 |
| EP1149067B1 (de) | 2004-02-25 |
| ZA200104271B (en) | 2002-08-26 |
| UY25861A1 (es) | 2001-07-31 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| DE59803292D1 (de) | Triazolverbindungen und deren verwendung als dopamin-d 3-liganden | |
| DE59903356D1 (de) | Blasensäule und deren verwendung | |
| PT853945E (pt) | Formulacoes liquidas contendo gonadotrofina | |
| EE200000283A (et) | Keemilised ühendid | |
| EE200000284A (et) | Keemilised ühendid | |
| EE200000285A (et) | Keemilised ühendid | |
| DE69816471D1 (de) | Pyrimidinon verbindungen und diese enthaltende pharmazeutische zusammenstellungen | |
| DE69520639T2 (de) | Desinfizierende Zusammensetzung | |
| DK1109449T3 (da) | Mikrokapselformuleringer | |
| NO20003312L (no) | <Gamma>-glutamyl og <beta>-aspartyl inneholdende immunmodulator-forbindelser og fremgangsmÕter derav | |
| NO20006425L (no) | Innkapslingsomslutning | |
| NO983958L (no) | Kjørbar understellsramme for rullestol | |
| DE69808403T2 (de) | Tetradecachlorcyclohexasilandianon enthaltende Verbindungen | |
| KR970703779A (ko) | 건강 조성물(health composition) | |
| ATE300525T1 (de) | Uracilverbindungen und deren verwendung | |
| DE69836972D1 (de) | Lysophophasäure enthaltende zusammensetzungen die die apoptose hemmen und deren verwendung | |
| ATE232683T1 (de) | Mikrokapsel-formulierungen | |
| DE69915128D1 (de) | 7-aryl-6(z)heptatriensäure retinamide als apoptose induzierende verbindungen und deren verwendung als antikrebsmittel | |
| NO20002797D0 (no) | Flytende sammensetning inneholdende minoxidil | |
| ID24677A (id) | Kombinasi senyawa aktif fungisidal | |
| DE69518322T2 (de) | C-4 amid substituierte verbindungen und deren verwendung als therapeutische mittel | |
| DE69802373T2 (de) | Schneckenreduktionsgetriebe | |
| DE69902094D1 (de) | Chemische reinigungszusammensetzung | |
| IT242819Y1 (it) | Confezione per la trasformazione di rifiuti di tipo vegetale-organico | |
| IT1303769B1 (it) | Catalizzatore e suo impiego per la sintesi di polioli polieteri. |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 8332 | No legal effect for de |