DE69911017T2 - Arylsulfonanilid-phosphate - Google Patents

Arylsulfonanilid-phosphate Download PDF

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Publication number
DE69911017T2
DE69911017T2 DE69911017T DE69911017T DE69911017T2 DE 69911017 T2 DE69911017 T2 DE 69911017T2 DE 69911017 T DE69911017 T DE 69911017T DE 69911017 T DE69911017 T DE 69911017T DE 69911017 T2 DE69911017 T2 DE 69911017T2
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DE
Germany
Prior art keywords
compound according
alkyl
group
formula
heteroalkyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69911017T
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German (de)
English (en)
Other versions
DE69911017D1 (en
Inventor
B. Jonathan HOUZE
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Amgen Inc
Original Assignee
Tularik Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Tularik Inc filed Critical Tularik Inc
Publication of DE69911017D1 publication Critical patent/DE69911017D1/de
Application granted granted Critical
Publication of DE69911017T2 publication Critical patent/DE69911017T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic System
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/655—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having oxygen atoms, with or without sulfur, selenium, or tellurium atoms, as the only ring hetero atoms
    • C07F9/65515—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having oxygen atoms, with or without sulfur, selenium, or tellurium atoms, as the only ring hetero atoms the oxygen atom being part of a five-membered ring
    • C07F9/65517—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having oxygen atoms, with or without sulfur, selenium, or tellurium atoms, as the only ring hetero atoms the oxygen atom being part of a five-membered ring condensed with carbocyclic rings or carbocyclic ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/06—Antipsoriatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic System
    • C07F9/02—Phosphorus compounds
    • C07F9/06—Phosphorus compounds without P—C bonds
    • C07F9/08—Esters of oxyacids of phosphorus
    • C07F9/09—Esters of phosphoric acids
    • C07F9/12—Esters of phosphoric acids with hydroxyaryl compounds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic System
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/645—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having two nitrogen atoms as the only ring hetero atoms
    • C07F9/6503—Five-membered rings
    • C07F9/6506—Five-membered rings having the nitrogen atoms in positions 1 and 3
    • C07F9/65068—Five-membered rings having the nitrogen atoms in positions 1 and 3 condensed with carbocyclic rings or carbocyclic ring systems

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  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Hematology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Obesity (AREA)
  • Diabetes (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
DE69911017T 1998-06-25 1999-06-16 Arylsulfonanilid-phosphate Expired - Fee Related DE69911017T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US9068198P 1998-06-25 1998-06-25
US90681P 1998-06-25
PCT/US1999/013759 WO1999067258A1 (en) 1998-06-25 1999-06-16 Arylsulfonanilide phosphates

Publications (2)

Publication Number Publication Date
DE69911017D1 DE69911017D1 (en) 2003-10-09
DE69911017T2 true DE69911017T2 (de) 2004-07-08

Family

ID=22223830

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69911017T Expired - Fee Related DE69911017T2 (de) 1998-06-25 1999-06-16 Arylsulfonanilid-phosphate

Country Status (8)

Country Link
US (2) US6211167B1 (US06211167-20010403-C00026.png)
EP (1) EP1090014B1 (US06211167-20010403-C00026.png)
JP (1) JP2002518506A (US06211167-20010403-C00026.png)
AT (1) ATE248845T1 (US06211167-20010403-C00026.png)
AU (1) AU763687B2 (US06211167-20010403-C00026.png)
CA (1) CA2335559A1 (US06211167-20010403-C00026.png)
DE (1) DE69911017T2 (US06211167-20010403-C00026.png)
WO (1) WO1999067258A1 (US06211167-20010403-C00026.png)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2244785C (en) * 1996-02-22 2003-12-02 Tularik, Inc. Pentafluorobenzenesulfonamides and analogs
CO5170498A1 (es) * 1999-05-28 2002-06-27 Abbott Lab Biaril sulfonamidas son utiles como inhibidores de proliferacion celular
EP1206256B8 (en) * 1999-07-29 2005-06-29 Amgen, Inc. Combination therapy using pentafluorobenzenesulfonamide and platin compound
AP2002002612A0 (en) * 2000-02-02 2002-09-30 Warner Lambert Co Dual inhibitors of cholesterol ester and wax ester synthesis for sebaceous gland disorders
US20050250854A1 (en) * 2000-11-03 2005-11-10 Amgen Inc. Combination therapy using pentafluorobenzenesulfonamides and antineoplastic agents
WO2002039958A2 (en) 2000-11-03 2002-05-23 Tularik Inc. Combination therapy using pentafluorobenzenesulfonamides and antineoplastic agents
GB0224830D0 (en) * 2002-10-24 2002-12-04 Sterix Ltd Compound
DE102007052174A1 (de) * 2007-10-30 2009-05-07 Ovd Kinegram Ag Folienelement zur Sicherung eines Gegenstandes
WO2021099842A1 (en) * 2019-11-22 2021-05-27 2692372 Ontario Inc. Pentafluorobenzenesulfonamide derivatives and uses thereof

Family Cites Families (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US1955207A (en) 1931-09-16 1934-04-17 Ig Farbenindustrie Ag Mothproofing agent
DE622494C (de) 1932-01-03 1935-11-29 I G Farbenindustrie Akt Ges Verfahren zur Darstellung von Mono- bzw. Polynitropolysulfonen und deren Reduktionsprodukten
US2358365A (en) 1940-08-03 1944-09-19 Parke Davis & Co Sulphonamide derivatives and process for obtaining the same
US2402623A (en) 1943-06-24 1946-06-25 Rohm & Haas Nu-nitroaryl haloarylsulphonamides
CH361275A (de) 1957-09-10 1962-04-15 Geigy Ag J R Verfahren zur Herstellung von neuen Arylsulfonarylamiden
GB938890A (en) 1961-02-03 1963-10-09 Boots Pure Drug Co Ltd New fungicidal compositions and compounds
CH504416A (de) 1966-12-05 1971-03-15 Ciba Geigy Ag Verfahren zur Herstellung von aromatischen Sulfamoylverbindungen
GB1242057A (en) 1968-07-04 1971-08-11 Ici Ltd Derivatives of 4-hydroxytetrafluoropyridine and the use thereof as plant growth regulators
NL174644C (nl) 1970-04-13 1984-07-16 Minnesota Mining & Mfg Werkwijze ter bereiding van een herbicide verbinding; tevens werkwijze voor de bereiding van een preparaat met herbicide werking.
DE3623184A1 (de) 1986-07-10 1988-01-14 Kali Chemie Ag Verfahren zur herstellung von n-fluorsulfonamiden
US4883914A (en) 1987-08-17 1989-11-28 American Cyanamid Company Benzenesulfonyl carboxamide compounds useful as herbicidal agents
DE3804990A1 (de) 1988-02-18 1989-08-31 Basf Ag Herbizid wirksame, heterocyclisch substituierte sulfonamide
JPH0651711B2 (ja) * 1988-06-29 1994-07-06 株式会社大塚製薬工場 ホスホン酸ジエステル誘導体
DE3905075A1 (de) 1989-02-18 1990-08-30 Hoechst Ag Benzolsulfonamide und verfahren zu ihrer herstellung
FR2645537B1 (fr) 1989-04-05 1994-03-04 Fabre Medicament Pierre Nouveaux sulfonamides derives d'acides benzocycliques ou benzoheterocycliques, leur preparation et leur application en therapeutique
FR2665440B1 (fr) 1990-07-31 1994-02-04 Lipha Nouveaux cycloalkylsulfonamides substitues, procedes de preparation et medicaments les contenant.
US5189211A (en) 1990-08-01 1993-02-23 Taisho Pharmaceutical Co., Ltd. Sulfonamide derivatives
EP0472053B1 (en) 1990-08-20 1998-06-17 Eisai Co., Ltd. Sulfonamide derivatives
US5561122A (en) * 1994-12-22 1996-10-01 Arizona Board Of Regents Acting On Behalf Of Arizona State University Combretastatin A-4 prodrug
US5529989A (en) * 1995-01-09 1996-06-25 Arizona Board Of Regents Acting On Behalf Of Arizona State University Pancratistatin prodrug
CA2244785C (en) * 1996-02-22 2003-12-02 Tularik, Inc. Pentafluorobenzenesulfonamides and analogs
AU710173B2 (en) * 1996-07-19 1999-09-16 Tularik Inc. Pentafluorobenzenesulfonamides and analogs
US6284923B1 (en) * 1997-08-22 2001-09-04 Tularik Inc Substituted benzene compounds as antiproliferative and cholesterol lowering action

Also Published As

Publication number Publication date
ATE248845T1 (de) 2003-09-15
DE69911017D1 (en) 2003-10-09
US6417176B2 (en) 2002-07-09
WO1999067258A1 (en) 1999-12-29
US20010018430A1 (en) 2001-08-30
JP2002518506A (ja) 2002-06-25
AU763687B2 (en) 2003-07-31
EP1090014B1 (en) 2003-09-03
EP1090014A1 (en) 2001-04-11
CA2335559A1 (en) 1999-12-29
AU4576899A (en) 2000-01-10
US6211167B1 (en) 2001-04-03

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Legal Events

Date Code Title Description
8327 Change in the person/name/address of the patent owner

Owner name: AMGEN INC., THOUSAND OAKS, CALIF., US

8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee