DE69910755D1 - Verwendung von 7-acyltaxolen zur behandlung von multidrugresistenten zellen - Google Patents
Verwendung von 7-acyltaxolen zur behandlung von multidrugresistenten zellenInfo
- Publication number
- DE69910755D1 DE69910755D1 DE69910755T DE69910755T DE69910755D1 DE 69910755 D1 DE69910755 D1 DE 69910755D1 DE 69910755 T DE69910755 T DE 69910755T DE 69910755 T DE69910755 T DE 69910755T DE 69910755 D1 DE69910755 D1 DE 69910755D1
- Authority
- DE
- Germany
- Prior art keywords
- taxols
- acyl
- resistant cells
- multidrug resistant
- treating multidrug
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D305/00—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms
- C07D305/14—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms condensed with carbocyclic rings or ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Hematology (AREA)
- Oncology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Epoxy Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US58036 | 1998-04-10 | ||
US09/058,036 US6136988A (en) | 1998-04-10 | 1998-04-10 | 7-hexanoyltaxol and methods for preparing the same |
PCT/US1999/007880 WO1999052887A1 (en) | 1998-04-10 | 1999-04-09 | 7-hexanoyltaxol and methods for preparing the same |
Publications (2)
Publication Number | Publication Date |
---|---|
DE69910755D1 true DE69910755D1 (de) | 2003-10-02 |
DE69910755T2 DE69910755T2 (de) | 2004-07-01 |
Family
ID=22014264
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69910755T Expired - Fee Related DE69910755T2 (de) | 1998-04-10 | 1999-04-09 | Verwendung von 7-acyltaxolen zur behandlung von multidrugresistenten zellen |
Country Status (8)
Country | Link |
---|---|
US (3) | US6136988A (de) |
EP (1) | EP1070057B1 (de) |
JP (1) | JP2002511457A (de) |
AT (1) | ATE248156T1 (de) |
AU (1) | AU757211B2 (de) |
CA (1) | CA2327791A1 (de) |
DE (1) | DE69910755T2 (de) |
WO (1) | WO1999052887A1 (de) |
Families Citing this family (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6136988A (en) * | 1998-04-10 | 2000-10-24 | Hauser, Inc. | 7-hexanoyltaxol and methods for preparing the same |
WO2000041687A2 (en) * | 1999-01-12 | 2000-07-20 | Quanam Medical Corporation | Composition and methods for administration of water-insoluble paclitaxel derivatives |
WO2000053231A2 (en) * | 1999-03-09 | 2000-09-14 | Protarga, Inc. | Fatty acid-anticancer conjugates and uses thereof |
AU776216B2 (en) * | 1999-05-28 | 2004-09-02 | Bristol-Myers Squibb Company | Semi-synthesis of paclitaxel using dialkyldichlorosilanes |
AR030188A1 (es) | 2000-02-02 | 2003-08-13 | Univ Florida State Res Found | Compuestos de taxano sustituidos con esteres en el c7; composiciones farmaceuticas que los contienen y proceso para tratar un sujeto mamifero que sufre de una condicion que responde a los taxanos |
CN1362957A (zh) | 2000-02-02 | 2002-08-07 | 佛罗里达州立大学研究基金有限公司 | 作为抗肿瘤剂的c7杂取代乙酸酯取代的紫杉烷 |
US6624317B1 (en) * | 2000-09-25 | 2003-09-23 | The University Of North Carolina At Chapel Hill | Taxoid conjugates as antimitotic and antitumor agents |
US20070113575A1 (en) * | 2003-12-05 | 2007-05-24 | Ritchie Engineering Company, Inc. | Valve manifold assembly |
WO2005087222A1 (en) | 2004-03-05 | 2005-09-22 | Florida State University Research Foundation, Inc. | C7 lactyloxy-substituted taxanes |
US7449196B2 (en) * | 2004-07-09 | 2008-11-11 | Robert Sabin | Anti tumor compositions and methods of use |
US20080081051A1 (en) * | 2006-09-28 | 2008-04-03 | Robert Sabin | Method of manufacturing anti-tumor and anti-viral compositions |
CN101735179B (zh) * | 2008-11-19 | 2012-09-12 | 上海百灵医药科技有限公司 | 一种多烯紫杉醇的制备方法,其中间体及制备方法 |
CN103242267B (zh) * | 2012-02-03 | 2015-03-18 | 福建南方制药股份有限公司 | 卡巴他赛及其中间体的制备方法及卡巴他赛中间体 |
Family Cites Families (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE4039319A1 (de) | 1990-12-10 | 1992-06-11 | Sicowa Verfahrenstech | Verfahren zum herstellen von gipsbaustoffen |
US5227400A (en) * | 1991-09-23 | 1993-07-13 | Florida State University | Furyl and thienyl substituted taxanes and pharmaceutical compositions containing them |
US5284864A (en) * | 1991-09-23 | 1994-02-08 | Florida State University | Butenyl substituted taxanes and pharmaceutical compositions containing them |
US5250683A (en) * | 1991-09-23 | 1993-10-05 | Florida State University | Certain substituted taxanes and pharmaceutical compositions containing them |
US5283253A (en) * | 1991-09-23 | 1994-02-01 | Florida State University | Furyl or thienyl carbonyl substituted taxanes and pharmaceutical compositions containing them |
US5243045A (en) * | 1991-09-23 | 1993-09-07 | Florida State University | Certain alkoxy substituted taxanes and pharmaceutical compositions containing them |
US5721268A (en) * | 1991-09-23 | 1998-02-24 | Florida State University | C7 taxane derivatives and pharmaceutical compositions containing them |
EP0639186B1 (de) * | 1992-04-17 | 1999-06-23 | Abbott Laboratories | Taxol-derivate |
WO1994005282A1 (en) * | 1992-09-04 | 1994-03-17 | The Scripps Research Institute | Water soluble taxol derivatives |
US5380751A (en) * | 1992-12-04 | 1995-01-10 | Bristol-Myers Squibb Company | 6,7-modified paclitaxels |
US5580899A (en) | 1995-01-09 | 1996-12-03 | The Liposome Company, Inc. | Hydrophobic taxane derivatives |
US6136988A (en) * | 1998-04-10 | 2000-10-24 | Hauser, Inc. | 7-hexanoyltaxol and methods for preparing the same |
-
1998
- 1998-04-10 US US09/058,036 patent/US6136988A/en not_active Expired - Fee Related
-
1999
- 1999-04-09 AT AT99916599T patent/ATE248156T1/de not_active IP Right Cessation
- 1999-04-09 CA CA002327791A patent/CA2327791A1/en not_active Abandoned
- 1999-04-09 AU AU34888/99A patent/AU757211B2/en not_active Ceased
- 1999-04-09 WO PCT/US1999/007880 patent/WO1999052887A1/en active IP Right Grant
- 1999-04-09 EP EP99916599A patent/EP1070057B1/de not_active Expired - Lifetime
- 1999-04-09 DE DE69910755T patent/DE69910755T2/de not_active Expired - Fee Related
- 1999-04-09 JP JP2000543447A patent/JP2002511457A/ja active Pending
-
2000
- 2000-10-16 US US09/688,753 patent/US6469050B1/en not_active Expired - Lifetime
-
2002
- 2002-07-19 US US10/199,826 patent/US6753345B2/en not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
EP1070057A4 (de) | 2001-09-05 |
CA2327791A1 (en) | 1999-10-21 |
AU3488899A (en) | 1999-11-01 |
AU757211B2 (en) | 2003-02-06 |
US6136988A (en) | 2000-10-24 |
EP1070057A1 (de) | 2001-01-24 |
WO1999052887A1 (en) | 1999-10-21 |
US6753345B2 (en) | 2004-06-22 |
ATE248156T1 (de) | 2003-09-15 |
DE69910755T2 (de) | 2004-07-01 |
EP1070057B1 (de) | 2003-08-27 |
US6469050B1 (en) | 2002-10-22 |
JP2002511457A (ja) | 2002-04-16 |
US20030083367A1 (en) | 2003-05-01 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8339 | Ceased/non-payment of the annual fee |