DE69908771D1 - Tilidin-mesylat, verfahren zu dessen herstellung und pharmazeutische zusammensetzungen - Google Patents

Tilidin-mesylat, verfahren zu dessen herstellung und pharmazeutische zusammensetzungen

Info

Publication number
DE69908771D1
DE69908771D1 DE69908771T DE69908771T DE69908771D1 DE 69908771 D1 DE69908771 D1 DE 69908771D1 DE 69908771 T DE69908771 T DE 69908771T DE 69908771 T DE69908771 T DE 69908771T DE 69908771 D1 DE69908771 D1 DE 69908771D1
Authority
DE
Germany
Prior art keywords
tilidine
production
pharmaceutical compositions
tilidine mesylate
mesylate
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69908771T
Other languages
English (en)
Other versions
DE69908771T2 (de
Inventor
Helmut Shickaneder
Aggelos Nikolopoulos
Brian Bruton
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Hexal AG
Original Assignee
Russinsky Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Russinsky Ltd filed Critical Russinsky Ltd
Application granted granted Critical
Publication of DE69908771D1 publication Critical patent/DE69908771D1/de
Publication of DE69908771T2 publication Critical patent/DE69908771T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C229/46—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino or carboxyl groups bound to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
    • C07C229/48—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino or carboxyl groups bound to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with amino groups and carboxyl groups bound to carbon atoms of the same non-condensed ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/07—Optical isomers
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/16—Systems containing only non-condensed rings with a six-membered ring the ring being unsaturated

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Saccharide Compounds (AREA)
DE69908771T 1998-04-28 1999-04-09 Tilidin-mesylat, verfahren zu dessen herstellung und pharmazeutische zusammensetzungen Expired - Lifetime DE69908771T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
IE980322 1998-04-28
IE980322 1998-04-28
PCT/IE1999/000024 WO1999055662A1 (en) 1998-04-28 1999-04-09 Tilidine mesylate, processes for its preparation and pharmaceutical composition thereof

Publications (2)

Publication Number Publication Date
DE69908771D1 true DE69908771D1 (de) 2003-07-17
DE69908771T2 DE69908771T2 (de) 2004-04-22

Family

ID=11041785

Family Applications (2)

Application Number Title Priority Date Filing Date
DE69908771T Expired - Lifetime DE69908771T2 (de) 1998-04-28 1999-04-09 Tilidin-mesylat, verfahren zu dessen herstellung und pharmazeutische zusammensetzungen
DE19981795T Withdrawn DE19981795T1 (de) 1998-04-28 1999-04-09 Tilidinmesylat, Verfahren zu dessen Herstellung und pharmazeutische Zusammensetzung davon

Family Applications After (1)

Application Number Title Priority Date Filing Date
DE19981795T Withdrawn DE19981795T1 (de) 1998-04-28 1999-04-09 Tilidinmesylat, Verfahren zu dessen Herstellung und pharmazeutische Zusammensetzung davon

Country Status (9)

Country Link
EP (1) EP1073625B1 (de)
AT (2) AT500119A1 (de)
AU (1) AU744888B2 (de)
DE (2) DE69908771T2 (de)
DK (1) DK1073625T3 (de)
ES (1) ES2204119T3 (de)
PT (1) PT1073625E (de)
WO (1) WO1999055662A1 (de)
ZA (1) ZA200001587B (de)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19859636A1 (de) * 1998-12-23 2000-06-29 Hexal Ag Kontrolliert freisetzende pharmazeutische Zusammensetzung mit Tilidinmesylat als Wirkstoff
EP2168945A1 (de) * 2008-09-26 2010-03-31 Hexal Ag Kristalline Formen von Tilidinmesylat

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR5978M (de) * 1965-11-19 1968-04-22
DE1923620C3 (de) * 1968-05-08 1971-06-24 Goedecke Ag Verfahren zur Herstellung basisch substituierter Cyclohexene bzw. von deren Salzen
DE1768704B1 (de) * 1968-06-21 1971-11-11 Goedecke Ag Verfahren zur Abtrennung von 3-trans-Dimethylamino-4-phenyl-4-trans-carbaethoxy-delta?-cyclohexen
DE2107871B2 (de) * 1971-02-18 1973-07-19 1-phenyl-4-amino-cyclohex-2-en-1 carbonsaeureester, verfahren zu deren herstellung und diese enthaltende analgetisch wirksame arzneimittel
CS214312B1 (cs) * 1980-11-03 1982-04-09 Ladislav David Sposob přípravy 3-tran s-dimetylamina-A-tran karbetoxy-l-cyklohexénu
DK0665830T3 (da) * 1992-10-26 1997-09-01 Goedecke Ag Tilidin-dihydrogenorthophosphat, fremgangsmåde til fremstilling deraf og farmaceutiske præparater indeholdende det.

Also Published As

Publication number Publication date
DE69908771T2 (de) 2004-04-22
DE19981795T1 (de) 2001-05-10
PT1073625E (pt) 2003-11-28
IE990299A1 (en) 2000-12-13
AT500119A1 (de) 2005-10-15
ZA200001587B (en) 2000-10-25
AU3440299A (en) 1999-11-16
ATE242760T1 (de) 2003-06-15
EP1073625B1 (de) 2003-06-11
ES2204119T3 (es) 2004-04-16
DK1073625T3 (da) 2003-09-29
EP1073625A1 (de) 2001-02-07
WO1999055662A1 (en) 1999-11-04
AU744888B2 (en) 2002-03-07

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Legal Events

Date Code Title Description
8327 Change in the person/name/address of the patent owner

Owner name: HEXAL AG, 83607 HOLZKIRCHEN, DE

8364 No opposition during term of opposition