DE69904578D1 - Verfahren zur sterilisation von nativem kollagen in einem flüssigmedium, sterile native kollagen zusammensetzungen und verwendung davon - Google Patents

Verfahren zur sterilisation von nativem kollagen in einem flüssigmedium, sterile native kollagen zusammensetzungen und verwendung davon

Info

Publication number
DE69904578D1
DE69904578D1 DE69904578T DE69904578T DE69904578D1 DE 69904578 D1 DE69904578 D1 DE 69904578D1 DE 69904578 T DE69904578 T DE 69904578T DE 69904578 T DE69904578 T DE 69904578T DE 69904578 D1 DE69904578 D1 DE 69904578D1
Authority
DE
Germany
Prior art keywords
native collagen
collagen
liquid medium
sterile
sterilizing
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69904578T
Other languages
English (en)
Other versions
DE69904578T2 (de
Inventor
Hamza Mansour
Original Assignee
Octapharma AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Octapharma AG filed Critical Octapharma AG
Publication of DE69904578D1 publication Critical patent/DE69904578D1/de
Application granted granted Critical
Publication of DE69904578T2 publication Critical patent/DE69904578T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/78—Connective tissue peptides, e.g. collagen, elastin, laminin, fibronectin, vitronectin or cold insoluble globulin [CIG]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
    • A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
    • A61L15/22—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons containing macromolecular materials
    • A61L15/32—Proteins, polypeptides; Degradation products or derivatives thereof, e.g. albumin, collagen, fibrin, gelatin
    • A61L15/325—Collagen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2/00—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
    • A61L2/0005—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor for pharmaceuticals, biologicals or living parts
    • A61L2/0011—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor for pharmaceuticals, biologicals or living parts using physical methods
    • A61L2/0017—Filtration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2/00—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
    • A61L2/0005—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor for pharmaceuticals, biologicals or living parts
    • A61L2/0082—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor for pharmaceuticals, biologicals or living parts using chemical substances
    • A61L2/0088—Liquid substances
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L26/00—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form
    • A61L26/0009—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form containing macromolecular materials
    • A61L26/0028—Polypeptides; Proteins; Degradation products thereof
    • A61L26/0033—Collagen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L26/00—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form
    • A61L26/0009—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form containing macromolecular materials
    • A61L26/0052—Mixtures of macromolecular compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/04—Macromolecular materials
    • A61L31/043—Proteins; Polypeptides; Degradation products thereof
    • A61L31/044—Collagen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Materials Engineering (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biomedical Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Hematology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Cardiology (AREA)
  • Surgery (AREA)
  • Vascular Medicine (AREA)
  • Diabetes (AREA)
  • Cosmetics (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Peptides Or Proteins (AREA)
  • Materials For Medical Uses (AREA)
  • Food Preservation Except Freezing, Refrigeration, And Drying (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Distillation Of Fermentation Liquor, Processing Of Alcohols, Vinegar And Beer (AREA)
DE69904578T 1998-04-10 1999-04-09 Verfahren zur sterilisation von nativem kollagen in einem flüssigmedium, sterile native kollagen zusammensetzungen und verwendung davon Expired - Fee Related DE69904578T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9804531A FR2777284B1 (fr) 1998-04-10 1998-04-10 Procede de sterilisation d'un collagene natif en milieu liquide, collagene natif sterile obtenu, compositions le contenant et applications
PCT/FR1999/000814 WO1999052946A1 (fr) 1998-04-10 1999-04-09 Procede de sterilisation d'un collagene natif en milieu liquide, collagene natif sterile obtenu, compositions le contenant et applications

Publications (2)

Publication Number Publication Date
DE69904578D1 true DE69904578D1 (de) 2003-01-30
DE69904578T2 DE69904578T2 (de) 2003-11-20

Family

ID=9525129

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69904578T Expired - Fee Related DE69904578T2 (de) 1998-04-10 1999-04-09 Verfahren zur sterilisation von nativem kollagen in einem flüssigmedium, sterile native kollagen zusammensetzungen und verwendung davon

Country Status (20)

Country Link
EP (1) EP1068240B1 (de)
JP (1) JP2002511489A (de)
KR (1) KR20010042539A (de)
CN (1) CN1304416A (de)
AT (1) ATE229982T1 (de)
AU (1) AU3151499A (de)
BR (1) BR9909566A (de)
CA (1) CA2327882A1 (de)
DE (1) DE69904578T2 (de)
EE (1) EE200000592A (de)
FR (1) FR2777284B1 (de)
HU (1) HUP0102575A2 (de)
ID (1) ID26038A (de)
IL (1) IL138562A0 (de)
NO (1) NO20005079L (de)
PL (1) PL343523A1 (de)
RU (1) RU2188206C2 (de)
WO (1) WO1999052946A1 (de)
YU (1) YU61100A (de)
ZA (1) ZA200005497B (de)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030017528A1 (en) 1998-11-20 2003-01-23 Ruoping Chen Human orphan G protein-coupled receptors
USRE42190E1 (en) 1998-11-20 2011-03-01 Arena Pharmaceuticals, Inc. Method of identifying a compound for inhibiting or stimulating human G protein-coupled receptors
US7816492B2 (en) 1998-11-20 2010-10-19 Arena Pharmaceuticals, Inc. Human G protein-coupled receptors
AT411326B (de) * 2000-06-20 2003-12-29 Biering Wolfgang Hämostatische collagen-pellets
JP4705359B2 (ja) * 2004-10-20 2011-06-22 新田ゼラチン株式会社 鳥類由来コラーゲンを用いてなる化粧料組成物
DE102005017845A1 (de) * 2005-04-18 2006-10-19 Lohmann & Rauscher Gmbh & Co. Kg Autosterile, antiseptische Kollagenzubereitungen, ihre Verwendung und Verfahren zu ihrer Herstellung
CN101332316B (zh) * 2008-07-22 2012-12-26 广东冠昊生物科技股份有限公司 生物型鼻梁植入体
US20080102095A1 (en) * 2006-10-31 2008-05-01 Kent Young Acidic processes to prepare antimicrobial contact lenses
CN101795704B (zh) * 2007-06-01 2014-07-30 协和发酵生化株式会社 经口组合物
RS56367B1 (sr) 2011-05-24 2017-12-29 Takeda As Umotani kolagenski nosač
DK2854735T3 (da) 2012-05-24 2019-05-13 Takeda As Apparat og fremgangsmåde til fremstilling af en opviklet kollagenbærer
WO2013174879A1 (en) 2012-05-24 2013-11-28 Takeda Nycomed As Packaging
CN102846536B (zh) * 2012-09-26 2014-03-26 关节动力安达（天津）生物科技有限公司 一种含有i型胶原蛋白的精华液
RU2597085C2 (ru) * 2013-11-07 2016-09-10 Федеральное государственное бюджетное учреждение науки Институт биологии моря им. А.В. Жирмунского Дальневосточного отделения Российской академии наук (ИБМ ДВО РАН) Имплантируемый матриксный материал для регенеративной медицины и способ его получения (варианты)
US20210115377A1 (en) * 2018-04-27 2021-04-22 Toppan Printing Co., Ltd. Extracellular-matrix-containing composition, temporary scaffold for three-dimensional tissue formation, three-dimensional tissue formation agent, and method for recovering cells from three-dimensional tissue
RU2715715C1 (ru) * 2019-03-06 2020-03-03 Общество с ограниченной ответственностью фирмы "Имтек" Стерильный прозрачный концентрированный раствор биосовместимого коллагена, способ его получения и применения
CN110354246A (zh) * 2019-07-22 2019-10-22 中肽生物科技(大连)有限公司 一种纳米级小分子复合肽养眼液的制备方法

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2462222A1 (de) * 1974-02-02 1976-05-06 Trommsdorff Fa H Loesliches, natives human-kollagen, dessen nicht-helikale peptide teilweise oder vollstaendig abgetrennt sind
US3949073A (en) * 1974-11-18 1976-04-06 The Board Of Trustees Of Leland Stanford Junior University Process for augmenting connective mammalian tissue with in situ polymerizable native collagen solution
DE3522626A1 (de) * 1985-06-25 1987-01-08 Merz & Co Gmbh & Co Loeslicher kollagen-schwamm
FR2586703B1 (fr) * 1985-09-02 1989-12-01 Merieux Inst Procede d'extraction de collagenes placentaires, collagenes obtenus notamment sous forme de gels ou de solutions et leurs applications
IT1181737B (it) * 1985-11-26 1987-09-30 Pierfrancesco Morganti Supproto di collagene biologicamente attivo per uso cosmetico e farmaceutico e metodo per prepararlo
FR2715309B1 (fr) * 1994-01-24 1996-08-02 Imedex Composition adhésive, à usage chirurgical, à base de collagène modifié par coupure oxydative et non réticulé.
CA2146090C (en) * 1994-05-10 1998-11-24 Mark E. Mitchell Apparatus and method of mixing materials in a sterile environment
US5670369A (en) * 1996-06-25 1997-09-23 Ranpak Corporation Method for the production of soluble collagen

Also Published As

Publication number Publication date
ZA200005497B (en) 2001-04-24
FR2777284B1 (fr) 2000-05-26
NO20005079D0 (no) 2000-10-09
ATE229982T1 (de) 2003-01-15
EE200000592A (et) 2002-04-15
AU3151499A (en) 1999-11-01
RU2188206C2 (ru) 2002-08-27
FR2777284A1 (fr) 1999-10-15
YU61100A (sh) 2003-10-31
CN1304416A (zh) 2001-07-18
IL138562A0 (en) 2001-10-31
DE69904578T2 (de) 2003-11-20
EP1068240A1 (de) 2001-01-17
CA2327882A1 (en) 1999-10-21
NO20005079L (no) 2000-12-08
JP2002511489A (ja) 2002-04-16
EP1068240B1 (de) 2002-12-18
HUP0102575A2 (hu) 2001-11-28
ID26038A (id) 2000-11-16
PL343523A1 (en) 2001-08-27
BR9909566A (pt) 2000-12-26
WO1999052946A1 (fr) 1999-10-21
KR20010042539A (ko) 2001-05-25

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Legal Events

Date Code Title Description
8327 Change in the person/name/address of the patent owner

Owner name: MANSOUR, HAMZA, LINGOLSHEIM, FR

8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee