DE69839947D1 - Cyanidfreie lytische Reagenzzusammensetzung und Vefahren zur Hämoglobin- und Zellanalyse - Google Patents

Cyanidfreie lytische Reagenzzusammensetzung und Vefahren zur Hämoglobin- und Zellanalyse

Info

Publication number
DE69839947D1
DE69839947D1 DE69839947T DE69839947T DE69839947D1 DE 69839947 D1 DE69839947 D1 DE 69839947D1 DE 69839947 T DE69839947 T DE 69839947T DE 69839947 T DE69839947 T DE 69839947T DE 69839947 D1 DE69839947 D1 DE 69839947D1
Authority
DE
Germany
Prior art keywords
hemoglobin
cyanide
methods
reagent composition
cell analysis
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69839947T
Other languages
English (en)
Inventor
Yi Li
Carole Young
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Beckman Coulter Inc
Original Assignee
Beckman Coulter Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Beckman Coulter Inc filed Critical Beckman Coulter Inc
Application granted granted Critical
Publication of DE69839947D1 publication Critical patent/DE69839947D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/72Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood pigments, e.g. haemoglobin, bilirubin or other porphyrins; involving occult blood
    • G01N33/721Haemoglobin
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5094Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for blood cell populations
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56966Animal cells
    • G01N33/56972White blood cells
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10TTECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00Chemistry: analytical and immunological testing
    • Y10T436/10Composition for standardization, calibration, simulation, stabilization, preparation or preservation; processes of use in preparation for chemical testing
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10TTECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00Chemistry: analytical and immunological testing
    • Y10T436/10Composition for standardization, calibration, simulation, stabilization, preparation or preservation; processes of use in preparation for chemical testing
    • Y10T436/101666Particle count or volume standard or control [e.g., platelet count standards, etc.]
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10TTECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00Chemistry: analytical and immunological testing
    • Y10T436/10Composition for standardization, calibration, simulation, stabilization, preparation or preservation; processes of use in preparation for chemical testing
    • Y10T436/105831Protein or peptide standard or control [e.g., hemoglobin, etc.]
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10TTECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00Chemistry: analytical and immunological testing
    • Y10T436/10Composition for standardization, calibration, simulation, stabilization, preparation or preservation; processes of use in preparation for chemical testing
    • Y10T436/107497Preparation composition [e.g., lysing or precipitation, etc.]
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10TTECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00Chemistry: analytical and immunological testing
    • Y10T436/10Composition for standardization, calibration, simulation, stabilization, preparation or preservation; processes of use in preparation for chemical testing
    • Y10T436/108331Preservative, buffer, anticoagulant or diluent
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10TTECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00Chemistry: analytical and immunological testing
    • Y10T436/25Chemistry: analytical and immunological testing including sample preparation
    • Y10T436/25125Digestion or removing interfering materials

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Immunology (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Cell Biology (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Food Science & Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Zoology (AREA)
  • Virology (AREA)
  • Ecology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
DE69839947T 1997-01-21 1998-01-13 Cyanidfreie lytische Reagenzzusammensetzung und Vefahren zur Hämoglobin- und Zellanalyse Expired - Lifetime DE69839947D1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US08/786,505 US5763280A (en) 1997-01-21 1997-01-21 Cyanide-free lytic reagent composition and method for hemoglobin and cell analysis

Publications (1)

Publication Number Publication Date
DE69839947D1 true DE69839947D1 (de) 2008-10-09

Family

ID=25138791

Family Applications (2)

Application Number Title Priority Date Filing Date
DE69816272T Expired - Lifetime DE69816272T2 (de) 1997-01-21 1998-01-13 Cyanidfreie lytische reagenzzusammensetzung und verfahren zur hämoglobin- und zellanalyse
DE69839947T Expired - Lifetime DE69839947D1 (de) 1997-01-21 1998-01-13 Cyanidfreie lytische Reagenzzusammensetzung und Vefahren zur Hämoglobin- und Zellanalyse

Family Applications Before (1)

Application Number Title Priority Date Filing Date
DE69816272T Expired - Lifetime DE69816272T2 (de) 1997-01-21 1998-01-13 Cyanidfreie lytische reagenzzusammensetzung und verfahren zur hämoglobin- und zellanalyse

Country Status (7)

Country Link
US (1) US5763280A (de)
EP (2) EP0960333B1 (de)
JP (2) JP4263247B2 (de)
CN (1) CN1154848C (de)
AU (1) AU5913498A (de)
DE (2) DE69816272T2 (de)
WO (1) WO1998032016A2 (de)

Families Citing this family (54)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU3094695A (en) * 1994-07-14 1996-02-16 Abbott Laboratories Methods and reagents for cyanide-free determination of hemoglobin and leukocytes in whole blood
US5882934A (en) * 1997-01-21 1999-03-16 Coulter International Corp. Composition and method for hemoglobin and cell analysis
FR2778413B1 (fr) * 1998-05-07 2000-08-04 Immunotech Sa Nouveaux reactifs et methode de lyse des erythrocytes
US6210969B1 (en) * 1999-04-28 2001-04-03 Coulter International Corp. Composition and method for differentiation of basophil and eosinophil subpopulations of leukocytes in blood
US6214625B1 (en) * 1999-04-28 2001-04-10 Coulter International Corp. Composition and method for differentiation of basophils and eosinophils in blood
EP1170593A3 (de) * 2000-06-19 2002-04-10 Felix Levine Feste Reagenzmischung, Testkit und Verfahren zur Bestimmung von Gesamteiweiss und Globulinen sowie von Hämoglobin in biologischen Flüssigkeitsproben
EP1182457A1 (de) * 2000-08-17 2002-02-27 Mallinckrodt Baker B.V. Verfahren und Reagens zur Analyse von Blutproben, im besonderen für tierärztliche Anwendungen
US6573102B2 (en) 2001-07-27 2003-06-03 Coulter International Corp. Lytic reagent composition for determination of nucleated blood cells
US6916658B2 (en) * 2001-07-27 2005-07-12 Beckman Coulter, Inc. Method for measurement of immature granulocytes
JP2005506525A (ja) 2001-07-27 2005-03-03 ベックマン コールター,インコーポレーテッド 有核赤血球の計測法の方法
US6410330B1 (en) 2001-07-27 2002-06-25 Coulter International Corp. Method for measurement of nucleated red blood cells
US6890756B2 (en) * 2002-04-05 2005-05-10 Streck Laboratories, Inc. Method of using cyanide-free lyse solution to emulate a cyanide-containing lyse solution in the measurement of hemoglobin
WO2003103108A1 (en) * 2002-05-31 2003-12-11 Pirelli & C. S.P.A. Cascaded raman pump for raman amplification in optical systems
EP1530710B1 (de) * 2002-06-11 2017-08-09 Koninklijke Philips N.V. Eine einwegkartusche zur charakterisierung von in einer flüssigkeit suspendierten partikeln
US7208319B2 (en) * 2004-02-10 2007-04-24 Beckman Coulter, Inc. Method of measurement of nucleated red blood cells
JP4911601B2 (ja) * 2004-02-10 2012-04-04 ベックマン コールター, インコーポレイテッド 有核赤血球細胞の計測方法
US7625712B2 (en) 2004-05-21 2009-12-01 Beckman Coulter, Inc. Method for a fully automated monoclonal antibody-based extended differential
US7674598B2 (en) * 2004-05-21 2010-03-09 Beckman Coulter, Inc. Method for a fully automated monoclonal antibody-based extended differential
US7465584B2 (en) * 2005-01-24 2008-12-16 Sysmex Corporation Method and reagent for classifying leukocytes in animal blood
JP5096170B2 (ja) 2005-02-10 2012-12-12 コーニンクレッカ フィリップス エレクトロニクス エヌ ヴィ デュアルサンプルカートリッジ及び液体中の粒子を特徴付ける方法
CA2855108A1 (en) * 2005-02-10 2006-08-17 Koninklijke Philips Electronics N.V. Dual sample cartridge and method for characterizing particles in liquid
US7235404B2 (en) * 2005-05-04 2007-06-26 Beckman Coulter, Inc. Cyanide-free lytic reagent composition and method of use for hemoglobin and white blood cell measurement
US7482165B2 (en) * 2005-08-24 2009-01-27 Beckman Coulter, Inc. Method of preventing white blood cell interferences to red blood cell measurements of a blood sample
US20070054404A1 (en) 2005-09-08 2007-03-08 Beckman Coulter, Inc. Method of hemoglobin correction due to temperature variation
US7586589B2 (en) * 2005-09-24 2009-09-08 Beckman Coulter, Inc. Methods of determination of responsiveness to erythropoietin treatment
US7609369B2 (en) * 2005-09-24 2009-10-27 Beckman Coulter, Inc. Methods of detection of iron deficiency and hemochromatosis
EP2330202A3 (de) 2006-01-06 2011-09-14 University Of Georgia Research Foundation, Inc. Zystennematoden-resistente transgene Pflanzen
US7361512B2 (en) * 2006-01-20 2008-04-22 Beckman Coulter, Inc. Low hemoglobin concentration cell percentage and method of use in detection of iron deficiency
CN101349644B (zh) * 2007-07-20 2012-06-27 深圳迈瑞生物医疗电子股份有限公司 一种白细胞分类试剂和其使用方法
US8102161B2 (en) * 2007-09-25 2012-01-24 Tdk Corporation Stable output in a switching power supply by smoothing the output of the secondary coil
WO2009058876A1 (en) * 2007-10-29 2009-05-07 Beckman Coulter, Inc. Method for a rapid antibody-based analysis of platelet populations
CN101451931B (zh) * 2007-12-04 2013-03-27 深圳迈瑞生物医疗电子股份有限公司 血液稀释液及其使用方法
CN101470108B (zh) * 2007-12-24 2013-11-27 深圳迈瑞生物医疗电子股份有限公司 一种对白细胞进行分类的试剂和方法
CN101475754A (zh) * 2008-01-04 2009-07-08 深圳迈瑞生物医疗电子股份有限公司 不对称菁类荧光染料,组合物及在生物样品染色中的用途
JP5669340B2 (ja) * 2008-01-23 2015-02-12 シスメックス株式会社 試料分析装置及び試料分析装置用プログラム
EP2280278A4 (de) * 2008-05-09 2015-04-08 Sysmex Corp Blutanalysator, blutanalyseverfahren und hämolytikum
CN101602762B (zh) * 2008-06-10 2013-10-16 深圳迈瑞生物医疗电子股份有限公司 不对称菁类化合物、其制备方法及应用
CN101363779B (zh) * 2008-06-26 2011-07-27 复旦大学 一种提高肽段离子化效率的方法
CN101726579B (zh) * 2008-10-17 2014-06-18 深圳迈瑞生物医疗电子股份有限公司 血液检测试剂和方法
EP2356465B1 (de) 2008-11-13 2014-10-01 Beckman Coulter, Inc. Verfahren zur korrektur von partikelinterferenz bei hämoglobinmessungen
US8367358B2 (en) * 2008-12-17 2013-02-05 Shenzhen Mindray Bio-Medical Electronics Co., Ltd. Reagent, kit and method for differentiating and counting leukocytes
EP2216095A1 (de) 2009-01-27 2010-08-11 Koninklijke Philips Electronics N.V. Mikrofluidische Vorrichtung für die Vollblutzählung
CN101988082B (zh) * 2009-07-31 2015-04-08 深圳迈瑞生物医疗电子股份有限公司 白细胞分类计数试剂、试剂盒及其制备方法和白细胞分类计数的方法
NL2005610A (en) * 2009-12-02 2011-06-06 Asml Netherlands Bv Lithographic apparatus and surface cleaning method.
US8906308B2 (en) 2010-01-15 2014-12-09 Abbott Laboratories Method for determining volume and hemoglobin content of individual red blood cells
CN102662067B (zh) * 2012-05-20 2014-07-02 烟台卓越生物技术有限责任公司 一种无氰化测定血红蛋白浓度及白细胞分群计数的溶血素
AU2016334875B2 (en) * 2015-10-07 2022-10-27 Sangui Bio Pty. Ltd Blood preparation and profiling
JP6811581B2 (ja) * 2016-10-25 2021-01-13 福井県 人血検査方法及び人血検査用キット
WO2018160216A1 (en) 2017-03-03 2018-09-07 Polymer Technology Systems, Inc. Systems and methods for enzymatic a1c detection and quantification
US11703513B2 (en) 2017-08-07 2023-07-18 Polymer Technology Systems, Inc. Systems and methods for enzymatic A1C detection and quantification
CN107907690B (zh) * 2017-11-15 2020-07-10 南通伊仕生物技术股份有限公司 一种超敏c反应蛋白检测试剂盒及其使用方法
CN110506122B (zh) * 2017-12-12 2023-09-29 聚合物技术系统公司 用于酶促a1c检测和定量的样品制备系统和方法
EP3794346B1 (de) * 2018-05-17 2023-03-08 Beckman Coulter, Inc. Grünes konzentriertes reagens für hämatologische systeme
US11191460B1 (en) 2020-07-15 2021-12-07 Shani Biotechnologies LLC Device and method for measuring blood components

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4185964A (en) * 1977-02-08 1980-01-29 Central Laboratories of Associated Maryland Pathologists, Ltd. Lysing reagent
US4528274A (en) * 1982-07-06 1985-07-09 Coulter Electronics, Inc. Multi-purpose blood diluent and lysing agent for differential determination of lymphoid-myeloid population of leukocytes
US4485175A (en) * 1983-01-03 1984-11-27 Coulter Electronics, Inc. Method for three-volume differential determination of lymphocyte, monocyte and granulocyte populations of leukocytes
US4880749A (en) * 1984-06-05 1989-11-14 Eastman Kodak Company Analytical element and its use in a whole blood hemoglobin assay
JP2615024B2 (ja) * 1986-10-03 1997-05-28 株式会社 ヤトロン モノクローナル抗体を用いたヒトヘモグロビンの高感度分析方法
JP2836865B2 (ja) * 1989-10-23 1998-12-14 東亜医用電子株式会社 血液中の白血球およびヘモグロビンの測定用試薬
SU1727067A1 (ru) * 1990-01-05 1992-04-15 Казанский государственный институт усовершенствования врачей им.В.И.Ленина Способ определени объема эритроцитов в биологической ткани
US5242832A (en) * 1990-03-01 1993-09-07 Toa Medical Electronics Co., Ltd. Reagent for measurement of leukocytes and hemoglobin in blood
DE69527947T2 (de) * 1994-03-11 2003-05-28 Abbott Laboratories, Abbott Park Cyanidfreies reagens und verfahren zur bestimmung von hämoglobin
US5686308A (en) * 1995-06-08 1997-11-11 Coulter Corporation Reagent and method for differential determination of leukocytes in blood

Also Published As

Publication number Publication date
JP4263247B2 (ja) 2009-05-13
DE69816272D1 (de) 2003-08-14
EP1298441A3 (de) 2004-08-11
EP0960333A2 (de) 1999-12-01
US5763280A (en) 1998-06-09
JP2008032750A (ja) 2008-02-14
EP1298441A2 (de) 2003-04-02
WO1998032016A2 (en) 1998-07-23
EP0960333B1 (de) 2003-07-09
EP1298441B1 (de) 2008-08-27
JP2001509273A (ja) 2001-07-10
AU5913498A (en) 1998-08-07
DE69816272T2 (de) 2004-04-22
CN1154848C (zh) 2004-06-23
WO1998032016A3 (en) 1998-12-03
CN1244259A (zh) 2000-02-09

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Owner name: BECKMAN COULTER, INC., BREA, CALIF., US