DE69838268T2 - Immonologisch aktiven, neuen Polypeptidefragmenten - Google Patents

Immonologisch aktiven, neuen Polypeptidefragmenten Download PDF

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Publication number
DE69838268T2
DE69838268T2 DE69838268T DE69838268T DE69838268T2 DE 69838268 T2 DE69838268 T2 DE 69838268T2 DE 69838268 T DE69838268 T DE 69838268T DE 69838268 T DE69838268 T DE 69838268T DE 69838268 T2 DE69838268 T2 DE 69838268T2
Authority
DE
Germany
Prior art keywords
polypeptide
fragment
tuberculosis
mycobacteria
polypeptide fragment
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69838268T
Other languages
German (de)
English (en)
Other versions
DE69838268D1 (de
Inventor
Peter Andersen
Walter Florio
Thomas Oettinger
Peter Birk Rasmussen
Ida Rosenkrands
Rikke Louise Vinther Skjöt
Karin Weldingh
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Statens Serum Institut SSI
Original Assignee
Statens Serum Institut SSI
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Statens Serum Institut SSI filed Critical Statens Serum Institut SSI
Publication of DE69838268D1 publication Critical patent/DE69838268D1/de
Application granted granted Critical
Publication of DE69838268T2 publication Critical patent/DE69838268T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/35Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Mycobacteriaceae (F)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • A61P31/06Antibacterial agents for tuberculosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/51Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Peptides Or Proteins (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Pulmonology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
DE69838268T 1997-04-02 1998-04-01 Immonologisch aktiven, neuen Polypeptidefragmenten Expired - Lifetime DE69838268T2 (de)

Applications Claiming Priority (8)

Application Number Priority Date Filing Date Title
DK37697 1997-04-02
DK37697 1997-04-02
US4462497P 1997-04-18 1997-04-18
US44624P 1997-04-18
DK127797 1997-11-10
DK127797 1997-11-10
US7048898P 1998-01-05 1998-01-05
US70488P 1998-01-05

Publications (2)

Publication Number Publication Date
DE69838268D1 DE69838268D1 (de) 2007-09-27
DE69838268T2 true DE69838268T2 (de) 2008-05-08

Family

ID=47018662

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69838268T Expired - Lifetime DE69838268T2 (de) 1997-04-02 1998-04-01 Immonologisch aktiven, neuen Polypeptidefragmenten

Country Status (10)

Country Link
EP (2) EP1449922B1 (enExample)
JP (4) JP4172598B2 (enExample)
AT (1) ATE370236T1 (enExample)
AU (1) AU740545B2 (enExample)
CA (1) CA2285625C (enExample)
DE (1) DE69838268T2 (enExample)
DK (1) DK1449922T3 (enExample)
ES (1) ES2291810T3 (enExample)
PT (1) PT1449922E (enExample)
WO (1) WO1998044119A1 (enExample)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6991797B2 (en) 1993-07-02 2006-01-31 Statens Serum Institut M. tuberculosis antigens
US6982085B2 (en) 1997-04-02 2006-01-03 Statens Serum Institut TB diagnostic based on antigens from M. tuberculosis
US7037510B2 (en) 1997-04-18 2006-05-02 Statens Serum Institut Hybrids of M. tuberculosis antigens
WO1999024577A1 (en) * 1997-11-10 1999-05-20 Statens Serum Institut NUCLEIC ACID FRAGMENTS AND POLYPEPTIDE FRAGMENTS DERIVED FROM $i(M. TUBERCULOSIS)
WO1999045119A2 (en) * 1998-03-06 1999-09-10 Statens Serum Institut Production of mycobacterial polypeptides by lactic acid bacteria
AU2594500A (en) * 1998-12-24 2000-07-31 Corixa Corporation Methods for using mycobacterium tuberculosis molecules as immunological adjuvants
DK1214088T3 (da) * 1999-05-04 2009-08-24 Univ New Jersey Med Proteiner udtrykt af Mycobacterium tuberculosis og ikke af BCG og anvendelse heraf som diagnostiske reagenser og vacciner
US6537552B1 (en) 1999-10-19 2003-03-25 Iowa State University Research Foundation Vaccine adjuvant
WO2001079274A2 (en) * 2000-04-19 2001-10-25 Statens Serum Institut Tuberculosis antigens and methods of use thereof
WO2002004018A2 (en) * 2000-07-10 2002-01-17 Colorado State University Research Foundation Mid-life vaccine and methods for boosting anti-mycobacterial immunity
WO2004099771A1 (en) 2003-05-08 2004-11-18 Statens Serum Institut A new specific epitope based immunological diagnosis of tuberculosis
NZ555907A (en) 2004-11-16 2009-12-24 Aeras Global Tb Vaccine Found Multivalent vaccines comprising recombinant viral vectors
EP1994409A2 (en) 2006-03-14 2008-11-26 Oregon Health and Science University Methods for producing an immune response to tuberculosis
GB0618127D0 (en) * 2006-09-14 2006-10-25 Isis Innovation Biomarker
EP2368568A1 (en) 2006-11-01 2011-09-28 Immport Therapeutics, INC. Compositions and methods for immunodominant antigens
WO2011013097A2 (en) * 2009-07-29 2011-02-03 Bernd Helmut Adam Rehm Polymer particles and uses thereof
US20130101614A1 (en) * 2010-06-15 2013-04-25 The Regents Of The University Of California Novel live recombinant booster vaccine against tuberculosis
US9926346B2 (en) 2012-04-16 2018-03-27 Aeras Recombinant mycobacterium encoding a heparin-binding hemagglutinin (HBHA) fusion protein and uses thereof
CN104897838B (zh) * 2015-06-10 2016-08-17 重庆医科大学 一种强极性有机酸碱混合物的同时提取分离分析方法
JP7772364B2 (ja) * 2019-05-07 2025-11-18 ナンヤン テクノロジカル ユニヴァーシティー Asx特異的タンパク質リガーゼおよびその使用
CN113373162A (zh) * 2020-03-09 2021-09-10 北京蛋白质组研究中心 结核分枝杆菌H37Rv新基因Rv0229A及其编码蛋白和应用
BR112022021258A2 (pt) * 2020-04-20 2023-01-17 Univ Saskatchewan Composições e métodos para prevenir, controlar e diagnosticar infecções micobacterianas
CN116082514B (zh) * 2021-11-05 2024-02-13 安博智联(北京)生物科技有限公司 结核分枝杆菌特异性的重组融合蛋白em及其应用

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK79893D0 (da) * 1993-07-02 1993-07-02 Statens Seruminstitut New vaccine
BR9608894A (pt) * 1995-05-23 1999-12-07 Univ California Produtos extracelulares abundantes e processos para suas producões e usos
DK1398379T3 (da) * 1995-09-01 2007-01-08 Corixa Corp Forbindelser og fremgangsmåder til immunterapi og diagnose af tuberkulose
ES2378051T3 (es) * 1995-09-01 2012-04-04 Corixa Corporation Compuestos y métodos para el diagnóstico de la tubercolosis.

Also Published As

Publication number Publication date
ES2291810T3 (es) 2008-03-01
DE69838268D1 (de) 2007-09-27
PT1449922E (pt) 2007-11-09
ATE370236T1 (de) 2007-09-15
EP1449922A2 (en) 2004-08-25
CA2285625C (en) 2015-06-30
AU740545B2 (en) 2001-11-08
EP1449922B1 (en) 2007-08-15
JP4406024B2 (ja) 2010-01-27
WO1998044119A1 (en) 1998-10-08
CA2285625A1 (en) 1998-10-08
JP2008301817A (ja) 2008-12-18
EP1449922A3 (en) 2004-11-17
JP2010154856A (ja) 2010-07-15
JP2008142079A (ja) 2008-06-26
DK1449922T3 (da) 2007-12-03
JP4172598B2 (ja) 2008-10-29
JP2001515359A (ja) 2001-09-18
JP4544434B2 (ja) 2010-09-15
AU6820498A (en) 1998-10-22
EP0972045A1 (en) 2000-01-19

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