CA2285625C - Nucleic acid fragments and polypeptide fragments derived from m. tuberculosis - Google Patents

Nucleic acid fragments and polypeptide fragments derived from m. tuberculosis Download PDF

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Publication number
CA2285625C
CA2285625C CA2285625A CA2285625A CA2285625C CA 2285625 C CA2285625 C CA 2285625C CA 2285625 A CA2285625 A CA 2285625A CA 2285625 A CA2285625 A CA 2285625A CA 2285625 C CA2285625 C CA 2285625C
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CA
Canada
Prior art keywords
ala
gly
val
leu
polypeptide
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
CA2285625A
Other languages
English (en)
French (fr)
Other versions
CA2285625A1 (en
Inventor
Peter Andersen
Rikke Skjot
Ida Rosenkrands
Karin Weldingh
Peter Birk Rasmussen
Thomas Oettinger
Walter Florio
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Statens Serum Institut SSI
Original Assignee
Statens Serum Institut SSI
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Statens Serum Institut SSI filed Critical Statens Serum Institut SSI
Publication of CA2285625A1 publication Critical patent/CA2285625A1/en
Application granted granted Critical
Publication of CA2285625C publication Critical patent/CA2285625C/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/35Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Mycobacteriaceae (F)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • A61P31/06Antibacterial agents for tuberculosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/51Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Oncology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Communicable Diseases (AREA)
  • Genetics & Genomics (AREA)
  • Peptides Or Proteins (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pulmonology (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biophysics (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
CA2285625A 1997-04-02 1998-04-01 Nucleic acid fragments and polypeptide fragments derived from m. tuberculosis Expired - Lifetime CA2285625C (en)

Applications Claiming Priority (9)

Application Number Priority Date Filing Date Title
DK37697 1997-04-02
DK0376/97 1997-04-02
US4462497P 1997-04-18 1997-04-18
US60/044,624 1997-04-18
DK127797 1997-11-10
DK1277/97 1997-11-10
US7048898P 1998-01-05 1998-01-05
US60/070,488 1998-01-05
PCT/DK1998/000132 WO1998044119A1 (en) 1997-04-02 1998-04-01 NUCLEIC ACID FRAGMENTS AND POLYPEPTIDE FRAGMENTS DERIVED FROM $i(M. TUBERCULOSIS)

Publications (2)

Publication Number Publication Date
CA2285625A1 CA2285625A1 (en) 1998-10-08
CA2285625C true CA2285625C (en) 2015-06-30

Family

ID=47018662

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2285625A Expired - Lifetime CA2285625C (en) 1997-04-02 1998-04-01 Nucleic acid fragments and polypeptide fragments derived from m. tuberculosis

Country Status (10)

Country Link
EP (2) EP0972045A1 (enExample)
JP (4) JP4172598B2 (enExample)
AT (1) ATE370236T1 (enExample)
AU (1) AU740545B2 (enExample)
CA (1) CA2285625C (enExample)
DE (1) DE69838268T2 (enExample)
DK (1) DK1449922T3 (enExample)
ES (1) ES2291810T3 (enExample)
PT (1) PT1449922E (enExample)
WO (1) WO1998044119A1 (enExample)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6991797B2 (en) 1993-07-02 2006-01-31 Statens Serum Institut M. tuberculosis antigens
US6982085B2 (en) 1997-04-02 2006-01-03 Statens Serum Institut TB diagnostic based on antigens from M. tuberculosis
US7037510B2 (en) 1997-04-18 2006-05-02 Statens Serum Institut Hybrids of M. tuberculosis antigens
CA2319380A1 (en) * 1997-11-10 1999-05-20 Statens Serum Institut Nucleic acid fragments and polypeptide fragments derived from m. tuberculosis
CA2322505A1 (en) * 1998-03-06 1999-09-10 Statens Serum Institut Production of mycobacterial polypeptides by lactic acid bacteria
AU2594500A (en) * 1998-12-24 2000-07-31 Corixa Corporation Methods for using mycobacterium tuberculosis molecules as immunological adjuvants
WO2000066157A1 (en) * 1999-05-04 2000-11-09 The Public Health Research Institute Of The City Of New York, Inc. Proteins expressed by mycobacterium tuberculosis and not by bcg and their use as diagnostic reagents and vaccines
US6537552B1 (en) 1999-10-19 2003-03-25 Iowa State University Research Foundation Vaccine adjuvant
CA2405247A1 (en) * 2000-04-19 2001-10-25 Statens Serum Institut Tuberculosis antigens and methods of use thereof
US7288261B2 (en) * 2000-07-10 2007-10-30 Colorado State University Research Foundation Mid-life vaccine and methods for boosting anti-mycobacterial immunity
WO2004099771A1 (en) 2003-05-08 2004-11-18 Statens Serum Institut A new specific epitope based immunological diagnosis of tuberculosis
EP1812580B1 (en) 2004-11-16 2014-12-17 Crucell Holland B.V. Multivalent vaccines comprising recombinant viral vectors
EP2441493B1 (en) 2006-03-14 2014-05-07 Oregon Health and Science University Methods for producing an immune response to tuberculosis
GB0618127D0 (en) * 2006-09-14 2006-10-25 Isis Innovation Biomarker
CA2668100C (en) 2006-11-01 2014-12-23 Immport Therapeutics, Inc. Compositions and methods for immunodominant antigens
CN102573891B (zh) * 2009-07-29 2016-06-01 贝恩德·赫尔穆特·阿达姆·雷姆 聚合物微粒及其用途
WO2011159814A2 (en) * 2010-06-15 2011-12-22 The Regents Of The University Of California Novel live recombinant booster vaccine against tuberculosis
US9926346B2 (en) 2012-04-16 2018-03-27 Aeras Recombinant mycobacterium encoding a heparin-binding hemagglutinin (HBHA) fusion protein and uses thereof
CN104897838B (zh) * 2015-06-10 2016-08-17 重庆医科大学 一种强极性有机酸碱混合物的同时提取分离分析方法
WO2020226572A1 (en) * 2019-05-07 2020-11-12 Nanyang Technological University Asx-specific protein ligases and uses thereof
CN113373162A (zh) * 2020-03-09 2021-09-10 北京蛋白质组研究中心 结核分枝杆菌H37Rv新基因Rv0229A及其编码蛋白和应用
CA3176303A1 (en) * 2020-04-20 2021-10-28 Antonio FACCIUOLO Compositions and methods for preventing, controlling and diagnosing mycobacterial infections
CN116082514B (zh) * 2021-11-05 2024-02-13 安博智联(北京)生物科技有限公司 结核分枝杆菌特异性的重组融合蛋白em及其应用

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK79893D0 (da) * 1993-07-02 1993-07-02 Statens Seruminstitut New vaccine
NZ309945A (en) * 1995-05-23 2001-04-27 Univ California Abundant extracellular products and their use as vaccines
CN1154730C (zh) * 1995-09-01 2004-06-23 科里克萨有限公司 用于结核病诊断的化合物和方法
NZ319377A (en) * 1995-09-01 2000-01-28 Corixa Corp polypeptides comprising a portion of a soluble M tuberculosis antigen

Also Published As

Publication number Publication date
AU740545B2 (en) 2001-11-08
JP4172598B2 (ja) 2008-10-29
DE69838268D1 (de) 2007-09-27
JP4406024B2 (ja) 2010-01-27
EP0972045A1 (en) 2000-01-19
WO1998044119A1 (en) 1998-10-08
CA2285625A1 (en) 1998-10-08
AU6820498A (en) 1998-10-22
JP2001515359A (ja) 2001-09-18
JP2008301817A (ja) 2008-12-18
JP2008142079A (ja) 2008-06-26
DK1449922T3 (da) 2007-12-03
DE69838268T2 (de) 2008-05-08
EP1449922A2 (en) 2004-08-25
PT1449922E (pt) 2007-11-09
ATE370236T1 (de) 2007-09-15
JP4544434B2 (ja) 2010-09-15
JP2010154856A (ja) 2010-07-15
EP1449922B1 (en) 2007-08-15
ES2291810T3 (es) 2008-03-01
EP1449922A3 (en) 2004-11-17

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Effective date: 20180403