DE69830910D1 - Kaliumkanal-proteine zur verwendung in gentherapie zur verminderung von erektiler dysfunktion - Google Patents
Kaliumkanal-proteine zur verwendung in gentherapie zur verminderung von erektiler dysfunktionInfo
- Publication number
- DE69830910D1 DE69830910D1 DE69830910T DE69830910T DE69830910D1 DE 69830910 D1 DE69830910 D1 DE 69830910D1 DE 69830910 T DE69830910 T DE 69830910T DE 69830910 T DE69830910 T DE 69830910T DE 69830910 D1 DE69830910 D1 DE 69830910D1
- Authority
- DE
- Germany
- Prior art keywords
- smooth muscle
- regulation
- protein involved
- present
- dna
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/43—Enzymes; Proenzymes; Derivatives thereof
- A61K38/45—Transferases (2)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y207/00—Transferases transferring phosphorus-containing groups (2.7)
- C12Y207/11—Protein-serine/threonine kinases (2.7.11)
- C12Y207/11013—Protein kinase C (2.7.11.13)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- Genetics & Genomics (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- General Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Epidemiology (AREA)
- Biochemistry (AREA)
- Gastroenterology & Hepatology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Immunology (AREA)
- Reproductive Health (AREA)
- Endocrinology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Gynecology & Obstetrics (AREA)
- Neurology (AREA)
- Physical Education & Sports Medicine (AREA)
- Physics & Mathematics (AREA)
- Biophysics (AREA)
- Plant Pathology (AREA)
- Microbiology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US799144 | 1997-02-13 | ||
US08/799,144 US6150338A (en) | 1997-02-13 | 1997-02-13 | Gene therapy for alleviating erectile dysfunction |
PCT/US1998/002249 WO1998036055A1 (en) | 1997-02-13 | 1998-02-05 | Gene therapy for alleviating erectile dysfunction |
Publications (2)
Publication Number | Publication Date |
---|---|
DE69830910D1 true DE69830910D1 (de) | 2005-08-25 |
DE69830910T2 DE69830910T2 (de) | 2006-04-20 |
Family
ID=25175134
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69830910T Expired - Lifetime DE69830910T2 (de) | 1997-02-13 | 1998-02-05 | Kaliumkanal-proteine zur verwendung in gentherapie zur verminderung von erektiler dysfunktion |
Country Status (12)
Country | Link |
---|---|
US (1) | US6150338A (de) |
EP (1) | EP1005538B1 (de) |
JP (1) | JP4158163B2 (de) |
KR (1) | KR100535782B1 (de) |
AT (1) | ATE299931T1 (de) |
AU (1) | AU745637B2 (de) |
CA (1) | CA2280770C (de) |
DE (1) | DE69830910T2 (de) |
DK (1) | DK1005538T3 (de) |
ES (1) | ES2246066T3 (de) |
PT (1) | PT1005538E (de) |
WO (1) | WO1998036055A1 (de) |
Families Citing this family (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7030096B1 (en) * | 1997-02-13 | 2006-04-18 | Albert Einstein College Of Medicine Of Yeshiva University | Method of enhancing relaxation of penile smooth muscle by introduction of DNA encoding maxi-K potassium channel protein |
US6271211B1 (en) | 1997-02-13 | 2001-08-07 | Albert Einstein College Of Medicine Of Yeshiva University | Gene therapy for regulating penile smooth muscle tone |
DK2075002T3 (da) * | 1998-05-01 | 2013-05-21 | Univ Pittsburgh | Myoblaster til reparation af urinvejslukkemuskel |
US6866842B1 (en) | 1998-05-01 | 2005-03-15 | University Of Pittsburgh | Muscle-derived cells (MDCs) for treating muscle-or bone-related injury or dysfunction |
US7115417B1 (en) | 1998-05-01 | 2006-10-03 | Chancellor Michael B | Soft tissue and bone augmentation and bulking utilizing muscle-derived progenito compositions, and treatments thereof |
KR20010076961A (ko) * | 2000-01-29 | 2001-08-17 | 김제종 | 성기능장애 예방 및 치료용 약제 |
CA2406393C (en) | 2000-04-14 | 2012-10-02 | University Of Pittsburgh | Soft tissue and bone augmentation and bulking utilizing muscle-derived progenitor cells, compositions and treatments thereof |
JP4680483B2 (ja) | 2001-02-23 | 2011-05-11 | ユニバーシティ オブ ピッツバーグ オブ ザ コモンウェルス システム オブ ハイヤー エデュケイション | 組織および臓器の治療および修復に用いるための幹細胞マトリックスの迅速な調製方法 |
DE602004029349D1 (de) | 2003-04-25 | 2010-11-11 | Univ Pittsburgh | Von muskeln stammende zellen (mdcs) zur förderung und verbesserung der nervenreparatur und -regeneration |
CN1621094A (zh) * | 2003-11-26 | 2005-06-01 | 犹太大学阿尔伯特爱因斯坦医学院 | 用于调节平滑肌张力的基因转移 |
EP2118271B1 (de) | 2007-01-11 | 2018-04-18 | University of Pittsburgh - Of the Commonwealth System of Higher Education | Zellen aus muskeln zur behandlung von harnwegserkrankungen sowie verfahren zu ihrer herstellung und verwendung |
US20090042208A1 (en) * | 2007-07-31 | 2009-02-12 | Davies Kelvin P | Assays for erectile and bladder dysfunction and vascular health |
AU2009282619B2 (en) | 2008-08-18 | 2015-08-20 | University Of Pittsburgh - Of The Commonwealth System Of Higher Education | Bone augmentation utilizing muscle-derived progenitor compositions in biocompatible matrix, and treatments thereof |
CN102242973B (zh) * | 2010-05-11 | 2013-10-09 | 爱烙达股份有限公司 | 热水器的储水桶 |
WO2020100089A2 (en) | 2018-11-14 | 2020-05-22 | Urovant Sciences Gmbh | Compositions and methods for the treatment of smooth muscle dysfunction |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0251244B1 (de) * | 1986-06-27 | 1996-09-04 | Takeda Chemical Industries, Ltd. | Polypeptid und dessen Herstellung |
US5324651A (en) * | 1986-06-27 | 1994-06-28 | Takeda Chemical Industries, Ltd. | DNA encoding rat and human protein kinase C |
DE3913954A1 (de) * | 1989-04-27 | 1990-10-31 | Stief Georg | Arzneimittel zur behandlung erektiler dysfunktionen |
US5594032A (en) * | 1994-11-10 | 1997-01-14 | Gonzalez-Cadavid; Nestor F. | Amelioration of human erectile dysfunction by treatment with iNOS, inducers of iNOS or iNOS cDNA |
-
1997
- 1997-02-13 US US08/799,144 patent/US6150338A/en not_active Expired - Lifetime
-
1998
- 1998-02-05 EP EP98906170A patent/EP1005538B1/de not_active Expired - Lifetime
- 1998-02-05 AT AT98906170T patent/ATE299931T1/de active
- 1998-02-05 WO PCT/US1998/002249 patent/WO1998036055A1/en not_active Application Discontinuation
- 1998-02-05 ES ES98906170T patent/ES2246066T3/es not_active Expired - Lifetime
- 1998-02-05 JP JP53582298A patent/JP4158163B2/ja not_active Expired - Lifetime
- 1998-02-05 DK DK98906170T patent/DK1005538T3/da active
- 1998-02-05 AU AU61468/98A patent/AU745637B2/en not_active Ceased
- 1998-02-05 CA CA002280770A patent/CA2280770C/en not_active Expired - Fee Related
- 1998-02-05 DE DE69830910T patent/DE69830910T2/de not_active Expired - Lifetime
- 1998-02-05 KR KR10-1999-7007330A patent/KR100535782B1/ko not_active IP Right Cessation
- 1998-02-05 PT PT98906170T patent/PT1005538E/pt unknown
Also Published As
Publication number | Publication date |
---|---|
EP1005538B1 (de) | 2005-07-20 |
ATE299931T1 (de) | 2005-08-15 |
AU745637B2 (en) | 2002-03-28 |
ES2246066T3 (es) | 2006-02-01 |
JP4158163B2 (ja) | 2008-10-01 |
KR20000071061A (ko) | 2000-11-25 |
KR100535782B1 (ko) | 2005-12-12 |
US6150338A (en) | 2000-11-21 |
WO1998036055A1 (en) | 1998-08-20 |
AU6146898A (en) | 1998-09-08 |
JP2001517935A (ja) | 2001-10-09 |
EP1005538A1 (de) | 2000-06-07 |
DK1005538T3 (da) | 2005-11-07 |
DE69830910T2 (de) | 2006-04-20 |
CA2280770C (en) | 2008-07-08 |
PT1005538E (pt) | 2005-11-30 |
EP1005538A4 (de) | 2002-12-04 |
CA2280770A1 (en) | 1998-08-20 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition |