ATE329030T1 - Nukleinsäure, welche einen von lektin abstammenden faktor zur präservierung von progenitorzellen kodiert - Google Patents

Nukleinsäure, welche einen von lektin abstammenden faktor zur präservierung von progenitorzellen kodiert

Info

Publication number
ATE329030T1
ATE329030T1 AT98931514T AT98931514T ATE329030T1 AT E329030 T1 ATE329030 T1 AT E329030T1 AT 98931514 T AT98931514 T AT 98931514T AT 98931514 T AT98931514 T AT 98931514T AT E329030 T1 ATE329030 T1 AT E329030T1
Authority
AT
Austria
Prior art keywords
progenitor cells
nucleic acid
vivo
protein
homolog
Prior art date
Application number
AT98931514T
Other languages
English (en)
Inventor
M Gabriella Colucci
Maarten J Chrispeels
Jeffrey G Moore
Original Assignee
Imclone Systems Inc
Univ California
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Imclone Systems Inc, Univ California filed Critical Imclone Systems Inc
Application granted granted Critical
Publication of ATE329030T1 publication Critical patent/ATE329030T1/de

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/87—Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation
    • C12N15/90—Stable introduction of foreign DNA into chromosome
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00—General protective or antinoxious agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/415—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from plants
    • C07K14/42—Lectins, e.g. concanavalin, phytohaemagglutinin
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0634—Cells from the blood or the immune system
    • C12N5/0647—Haematopoietic stem cells; Uncommitted or multipotent progenitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K2035/124—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells the cells being hematopoietic, bone marrow derived or blood cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/20—Cytokines; Chemokines
    • C12N2501/26—Flt-3 ligand (CD135L, flk-2 ligand)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/50—Cell markers; Cell surface determinants
    • C12N2501/59—Lectins

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Microbiology (AREA)
  • Hematology (AREA)
  • Medicinal Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Botany (AREA)
  • Cell Biology (AREA)
  • Immunology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Mycology (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Toxicology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
AT98931514T 1997-06-24 1998-06-23 Nukleinsäure, welche einen von lektin abstammenden faktor zur präservierung von progenitorzellen kodiert ATE329030T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US08/881,189 US6310195B1 (en) 1997-06-24 1997-06-24 Nucleic acid encoding a lectin-derived progenitor cell preservation factor

Publications (1)

Publication Number Publication Date
ATE329030T1 true ATE329030T1 (de) 2006-06-15

Family

ID=25377959

Family Applications (1)

Application Number Title Priority Date Filing Date
AT98931514T ATE329030T1 (de) 1997-06-24 1998-06-23 Nukleinsäure, welche einen von lektin abstammenden faktor zur präservierung von progenitorzellen kodiert

Country Status (9)

Country Link
US (4) US6310195B1 (de)
EP (1) EP1017789B1 (de)
JP (1) JP2002507120A (de)
AT (1) ATE329030T1 (de)
AU (1) AU8162698A (de)
CA (1) CA2294195A1 (de)
DE (1) DE69834824T2 (de)
ES (1) ES2265663T3 (de)
WO (1) WO1998059038A1 (de)

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* Cited by examiner, † Cited by third party
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US20020132017A1 (en) * 1996-12-09 2002-09-19 Moore Jeffrey G. Composition and method for preserving progenitor cells
US6991794B1 (en) * 1997-06-24 2006-01-31 Imclone Systems Incorporated Progenitor cell preservation factors and methods for and products of their use
US6310195B1 (en) 1997-06-24 2001-10-30 Imclone Systems Incorporated Nucleic acid encoding a lectin-derived progenitor cell preservation factor
EP1584686A1 (de) * 1999-12-30 2005-10-12 ImClone Systems Incorporated Stammzellen Schutzfaktor und verwandte Methoden und Produkte
CN1406280A (zh) * 1999-12-30 2003-03-26 弗洛吉克斯有限公司 祖细胞保护因子和相关的方法和产物
US20030134789A1 (en) * 2001-02-27 2003-07-17 Phylogix Llc Compositions and methods for protecting tissues and cells from damage, and for repairing damaged tissues
WO2003004616A2 (en) * 2001-07-05 2003-01-16 Phylogix, Inc. Dendritic cell isolation methods
US7482116B2 (en) 2002-06-07 2009-01-27 Dna Genotek Inc. Compositions and methods for obtaining nucleic acids from sputum
WO2007116408A2 (en) * 2006-04-11 2007-10-18 Nanodiagnostics Israel Ltd. Pluripotent stem cells characterized by expression of germline specific genes
EP1546346A4 (de) * 2002-07-23 2006-02-08 Nanodiagnostics Inc Embryonale stammzellen-marker und verwendungen davon
US8647867B2 (en) 2005-09-30 2014-02-11 National University Corportion Okayama University Cell cultivation method and cell culture
KR20090009186A (ko) * 2005-12-06 2009-01-22 디파트먼트 오브 바이오테크놀러지 사람의 조혈 줄기 세포 또는 선조 세포의 보존 방법
US8524453B2 (en) * 2006-02-10 2013-09-03 The Brigham And Woman's Hospital, Inc. Lectin complement pathway assays and related compositions and methods
JP2010516239A (ja) * 2007-01-18 2010-05-20 スオメン プナイネン リスティ，ヴェリパルベル 細胞の産生に対する新規方法および試薬
EP2137300B1 (de) 2007-04-26 2011-10-26 Ramot at Tel-Aviv University Ltd. Pluripotente autologe Stammzellen aus der mündlichen oder gastrointestinalen Schleimhaut
WO2010004096A2 (en) * 2008-07-11 2010-01-14 Suomen Punainen Risti Veripalvelu Culture of cells
US20100120142A1 (en) 2008-07-11 2010-05-13 Suomen Punainen Risti Veripalvelu Culture of human embryonic cells
US8642007B2 (en) 2010-09-20 2014-02-04 Yanping Kong Method and compound for treatment of cancer using phosphorous-32 labeled DNA
WO2012048275A2 (en) 2010-10-08 2012-04-12 Caridianbct, Inc. Configurable methods and systems of growing and harvesting cells in a hollow fiber bioreactor system
CN103890163B (zh) * 2011-06-19 2016-09-14 阿博根公司 用于样品采集的装置、溶液和方法
EP2782587B1 (de) 2011-11-21 2018-11-07 Ramot at Tel Aviv University, Ltd. Aus stammzellen gewonnene nervenzellen zur zelltherapie bei neurologischen krankheiten
WO2015073913A1 (en) 2013-11-16 2015-05-21 Terumo Bct, Inc. Expanding cells in a bioreactor
US11008547B2 (en) 2014-03-25 2021-05-18 Terumo Bct, Inc. Passive replacement of media
WO2016049421A1 (en) 2014-09-26 2016-03-31 Terumo Bct, Inc. Scheduled feed
JP7344631B2 (ja) 2015-02-09 2023-09-14 アボゲン， インコーポレイティド サンプル収集関連応用、分析および診断のためのデバイス、溶液および方法
WO2017004592A1 (en) 2015-07-02 2017-01-05 Terumo Bct, Inc. Cell growth with mechanical stimuli
EP3464565A4 (de) 2016-05-25 2020-01-01 Terumo BCT, Inc. Zellexpansion
US11685883B2 (en) 2016-06-07 2023-06-27 Terumo Bct, Inc. Methods and systems for coating a cell growth surface
US11104874B2 (en) 2016-06-07 2021-08-31 Terumo Bct, Inc. Coating a bioreactor
US11624046B2 (en) 2017-03-31 2023-04-11 Terumo Bct, Inc. Cell expansion
EP3656842A1 (de) 2017-03-31 2020-05-27 Terumo BCT, Inc. Zellexpansion
JP2024511064A (ja) 2021-03-23 2024-03-12 テルモ ビーシーティー、インコーポレーテッド 細胞捕獲及び増殖

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US4742046A (en) * 1984-08-03 1988-05-03 Medisearch S.A. Methods and compositions for inhibiting the infectious activity of viruses
US4808611A (en) 1986-07-30 1989-02-28 Immunex Corporation Use of interleukin-1 to induce development of multipotent hemopoietic cell populations
US5186931A (en) 1986-08-06 1993-02-16 Ajinomoto Co., Inc. Composition and method for supporting bone marrow transplantation
JPH0825890B2 (ja) * 1987-06-18 1996-03-13 呉羽化学工業株式会社 抗ウイルス剤
US5053386A (en) * 1987-07-24 1991-10-01 Tung Ta C Orally administrable anti-metastatic lectin compositions and methods
JP3322871B2 (ja) * 1990-07-30 2002-09-09 ノバルティス アクチエンゲゼルシャフト 殺虫性タンパク質
DE4240635C2 (de) 1992-12-03 1997-07-10 Lothar Prof Dr Kanz Vermehrung hämatopoetischer Vorläuferzellen ex vivo sowieZusammensetzungen hämatopoetischer Wachstumsfaktoren
WO1995000554A2 (en) 1993-06-18 1995-01-05 The Trustees Of Princeton University Totipotent hematopoietic stem cell receptors and their ligands
US6455678B1 (en) 1996-04-26 2002-09-24 Amcell Corporation Human hematopoietic stem and progenitor cell antigen
US6110891A (en) 1996-06-21 2000-08-29 Alizyme Therapeutics Ltd. Lectin compositions and uses thereof
GB9613070D0 (en) 1996-06-21 1996-08-28 Rowett Research Services Limit Dietary lectins
GB9718413D0 (en) 1997-08-29 1997-11-05 Alizyme Therapeutics Ltd Compositions
US6017527A (en) * 1996-07-10 2000-01-25 Immunex Corporation Activated dendritic cells and methods for their activation
US20020132017A1 (en) * 1996-12-09 2002-09-19 Moore Jeffrey G. Composition and method for preserving progenitor cells
US6084060A (en) 1996-12-09 2000-07-04 Imclone Systems Incorporated Composition and method for preserving progenitor cells
US6310195B1 (en) 1997-06-24 2001-10-30 Imclone Systems Incorporated Nucleic acid encoding a lectin-derived progenitor cell preservation factor
US6991794B1 (en) * 1997-06-24 2006-01-31 Imclone Systems Incorporated Progenitor cell preservation factors and methods for and products of their use
US6274378B1 (en) * 1997-10-27 2001-08-14 The Rockefeller University Methods and compositions for obtaining mature dendritic cells

Also Published As

Publication number Publication date
ES2265663T3 (es) 2007-02-16
US20050060779A1 (en) 2005-03-17
DE69834824T2 (de) 2006-12-28
EP1017789B1 (de) 2006-06-07
JP2002507120A (ja) 2002-03-05
AU8162698A (en) 1999-01-04
US6310195B1 (en) 2001-10-30
DE69834824D1 (de) 2006-07-20
CA2294195A1 (en) 1998-12-30
EP1017789A1 (de) 2000-07-12
WO1998059038A1 (en) 1998-12-30
EP1017789A4 (de) 2002-01-23
US20030049339A1 (en) 2003-03-13
US20070280904A1 (en) 2007-12-06
US6852321B2 (en) 2005-02-08

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