DK1005538T3 - Kaliumkanalproteiner til anvendelse i genterapi til afhjælpning af erektil dysfunktion - Google Patents

Kaliumkanalproteiner til anvendelse i genterapi til afhjælpning af erektil dysfunktion

Info

Publication number
DK1005538T3
DK1005538T3 DK98906170T DK98906170T DK1005538T3 DK 1005538 T3 DK1005538 T3 DK 1005538T3 DK 98906170 T DK98906170 T DK 98906170T DK 98906170 T DK98906170 T DK 98906170T DK 1005538 T3 DK1005538 T3 DK 1005538T3
Authority
DK
Denmark
Prior art keywords
smooth muscle
regulation
protein involved
present
dna
Prior art date
Application number
DK98906170T
Other languages
English (en)
Inventor
Arnold Melman
George J Christ
Jan Geliebter
Jamil Rehman
Original Assignee
Einstein Coll Med
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Einstein Coll Med filed Critical Einstein Coll Med
Application granted granted Critical
Publication of DK1005538T3 publication Critical patent/DK1005538T3/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/11DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43Enzymes; Proenzymes; Derivatives thereof
    • A61K38/45Transferases (2)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • A61P15/10Drugs for genital or sexual disorders; Contraceptives for impotence
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00Drugs for disorders of the muscular or neuromuscular system
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y207/00Transferases transferring phosphorus-containing groups (2.7)
    • C12Y207/11Protein-serine/threonine kinases (2.7.11)
    • C12Y207/11013Protein kinase C (2.7.11.13)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Gastroenterology & Hepatology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Reproductive Health (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Endocrinology (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Microbiology (AREA)
  • Neurology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
DK98906170T 1997-02-13 1998-02-05 Kaliumkanalproteiner til anvendelse i genterapi til afhjælpning af erektil dysfunktion DK1005538T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US08/799,144 US6150338A (en) 1997-02-13 1997-02-13 Gene therapy for alleviating erectile dysfunction

Publications (1)

Publication Number Publication Date
DK1005538T3 true DK1005538T3 (da) 2005-11-07

Family

ID=25175134

Family Applications (1)

Application Number Title Priority Date Filing Date
DK98906170T DK1005538T3 (da) 1997-02-13 1998-02-05 Kaliumkanalproteiner til anvendelse i genterapi til afhjælpning af erektil dysfunktion

Country Status (12)

Country Link
US (1) US6150338A (da)
EP (1) EP1005538B1 (da)
JP (1) JP4158163B2 (da)
KR (1) KR100535782B1 (da)
AT (1) ATE299931T1 (da)
AU (1) AU745637B2 (da)
CA (1) CA2280770C (da)
DE (1) DE69830910T2 (da)
DK (1) DK1005538T3 (da)
ES (1) ES2246066T3 (da)
PT (1) PT1005538E (da)
WO (1) WO1998036055A1 (da)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6271211B1 (en) 1997-02-13 2001-08-07 Albert Einstein College Of Medicine Of Yeshiva University Gene therapy for regulating penile smooth muscle tone
US7030096B1 (en) 1997-02-13 2006-04-18 Albert Einstein College Of Medicine Of Yeshiva University Method of enhancing relaxation of penile smooth muscle by introduction of DNA encoding maxi-K potassium channel protein
ES2319660T3 (es) * 1998-05-01 2009-05-11 University Of Pittsburgh Uso de mioblastos en la fabricacion de un medicamento para tratar la incontinencia urinaria de esfuerzo.
US7115417B1 (en) 1998-05-01 2006-10-03 Chancellor Michael B Soft tissue and bone augmentation and bulking utilizing muscle-derived progenito compositions, and treatments thereof
US6866842B1 (en) 1998-05-01 2005-03-15 University Of Pittsburgh Muscle-derived cells (MDCs) for treating muscle-or bone-related injury or dysfunction
KR20010076961A (ko) * 2000-01-29 2001-08-17 김제종 성기능장애 예방 및 치료용 약제
JP5684963B2 (ja) 2000-04-14 2015-03-18 ユニバーシティ オブ ピッツバーグ オブ ザ コモンウェルス システム オブ ハイヤー エデュケイション 筋肉由来前駆細胞、その組成物、および治療法を使用した軟部組織および骨の増大および肥厚
CA2438904C (en) 2001-02-23 2012-09-04 The University Of Pittsburgh Rapid preparation of stem cell matrices for use in tissue and organ treatment and repair
EP2289526B1 (en) 2003-04-25 2014-06-11 The University of Pittsburgh Muscle derived cells (mdcs) for promoting and enhancing nerve repair and regeneration.
CN1621094A (zh) * 2003-11-26 2005-06-01 犹太大学阿尔伯特爱因斯坦医学院 用于调节平滑肌张力的基因转移
JP5425641B2 (ja) 2007-01-11 2014-02-26 ユニバーシティー オブ ピッツバーグ − オブ ザ コモンウェルス システム オブ ハイヤー エデュケーション 尿路病状の処置のための筋由来細胞ならびにその作製および使用の方法
US20090042208A1 (en) * 2007-07-31 2009-02-12 Davies Kelvin P Assays for erectile and bladder dysfunction and vascular health
CA2734858C (en) 2008-08-18 2019-01-15 University Of Pittsburgh - Of The Commonwealth System Of Higher Education Bone augmentation utilizing muscle-derived progenitor compositions in biocompatible matrix, and treatments thereof
CN102242973B (zh) * 2010-05-11 2013-10-09 爱烙达股份有限公司 热水器的储水桶
US20220133849A1 (en) 2018-11-14 2022-05-05 Urovant Sciences Gmbh Compositions and methods for the treatment of smooth muscle dysfunction

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0251244B1 (en) * 1986-06-27 1996-09-04 Takeda Chemical Industries, Ltd. Polypeptide and production thereof
US5324651A (en) * 1986-06-27 1994-06-28 Takeda Chemical Industries, Ltd. DNA encoding rat and human protein kinase C
DE3913954A1 (de) * 1989-04-27 1990-10-31 Stief Georg Arzneimittel zur behandlung erektiler dysfunktionen
US5594032A (en) * 1994-11-10 1997-01-14 Gonzalez-Cadavid; Nestor F. Amelioration of human erectile dysfunction by treatment with iNOS, inducers of iNOS or iNOS cDNA

Also Published As

Publication number Publication date
ES2246066T3 (es) 2006-02-01
CA2280770C (en) 2008-07-08
JP4158163B2 (ja) 2008-10-01
EP1005538A4 (en) 2002-12-04
AU745637B2 (en) 2002-03-28
KR100535782B1 (ko) 2005-12-12
EP1005538A1 (en) 2000-06-07
AU6146898A (en) 1998-09-08
ATE299931T1 (de) 2005-08-15
WO1998036055A1 (en) 1998-08-20
PT1005538E (pt) 2005-11-30
KR20000071061A (ko) 2000-11-25
DE69830910D1 (de) 2005-08-25
US6150338A (en) 2000-11-21
DE69830910T2 (de) 2006-04-20
CA2280770A1 (en) 1998-08-20
JP2001517935A (ja) 2001-10-09
EP1005538B1 (en) 2005-07-20

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