DE69820975D1 - Verfahren zum Entfernen von Fumarase Aktivität, durch diese Verfahren erhältliche Mikroorganismen und Herstellung von optisch aktiven Aminopolycarbonsäuren mit diesen Mikroorganismen - Google Patents

Verfahren zum Entfernen von Fumarase Aktivität, durch diese Verfahren erhältliche Mikroorganismen und Herstellung von optisch aktiven Aminopolycarbonsäuren mit diesen Mikroorganismen

Info

Publication number
DE69820975D1
DE69820975D1 DE69820975T DE69820975T DE69820975D1 DE 69820975 D1 DE69820975 D1 DE 69820975D1 DE 69820975 T DE69820975 T DE 69820975T DE 69820975 T DE69820975 T DE 69820975T DE 69820975 D1 DE69820975 D1 DE 69820975D1
Authority
DE
Germany
Prior art keywords
microorganisms
processes
production
optically active
obtainable
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69820975T
Other languages
English (en)
Other versions
DE69820975T2 (de
Inventor
Mami Kato
Makoto Kaneko
Takakazu Endo
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Mitsubishi Rayon Co Ltd
Original Assignee
Mitsubishi Rayon Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mitsubishi Rayon Co Ltd filed Critical Mitsubishi Rayon Co Ltd
Publication of DE69820975D1 publication Critical patent/DE69820975D1/de
Application granted granted Critical
Publication of DE69820975T2 publication Critical patent/DE69820975T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/93—Ligases (6)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/38—Chemical stimulation of growth or activity by addition of chemical compounds which are not essential growth factors; Stimulation of growth by removal of a chemical compound
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/99—Enzyme inactivation by chemical treatment
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/04—Alpha- or beta- amino acids
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/80—Elimination or reduction of contamination by undersired ferments, e.g. aseptic cultivation
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/82—Subcellular parts of microorganisms
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/8215—Microorganisms
    • Y10S435/822—Microorganisms using bacteria or actinomycetales
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/8215—Microorganisms
    • Y10S435/822—Microorganisms using bacteria or actinomycetales
    • Y10S435/83—Arthrobacter
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/8215—Microorganisms
    • Y10S435/822—Microorganisms using bacteria or actinomycetales
    • Y10S435/848—Escherichia
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/8215—Microorganisms
    • Y10S435/822—Microorganisms using bacteria or actinomycetales
    • Y10S435/874—Pseudomonas

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
DE69820975T 1997-10-28 1998-10-28 Verfahren zum Entfernen von Fumarase Aktivität, durch diese Verfahren erhältliche Mikroorganismen und Herstellung von optisch aktiven Aminopolycarbonsäuren mit diesen Mikroorganismen Expired - Lifetime DE69820975T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP31104697 1997-10-28
JP31104697 1997-10-28

Publications (2)

Publication Number Publication Date
DE69820975D1 true DE69820975D1 (de) 2004-02-12
DE69820975T2 DE69820975T2 (de) 2005-01-27

Family

ID=18012466

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69820975T Expired - Lifetime DE69820975T2 (de) 1997-10-28 1998-10-28 Verfahren zum Entfernen von Fumarase Aktivität, durch diese Verfahren erhältliche Mikroorganismen und Herstellung von optisch aktiven Aminopolycarbonsäuren mit diesen Mikroorganismen

Country Status (3)

Country Link
US (1) US6103508A (de)
EP (1) EP0927762B1 (de)
DE (1) DE69820975T2 (de)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1043400B1 (de) * 1997-12-22 2006-09-13 Mitsubishi Rayon Co., Ltd. Verfahren für die herstellung von ¬s,s|-ethylendiamin-n,n'-di-bernsteinsäure
EP1174515B1 (de) * 1999-04-27 2008-03-19 Mitsubishi Rayon Co., Ltd. Verfahren zur herstellung von s,s-2-hydroxypropylendiamin-n,n'-di-bernsteinsäure
US20020160445A1 (en) * 2001-02-09 2002-10-31 Marianne Harboe Method of providing polypeptide preparations with reduced enzymatic side activities
DE602004019824D1 (de) * 2004-05-20 2009-04-16 Mitsubishi Rayon Co Modifizierte ethylendiamin-n,n'-dibernsteinsäure:ethylendiamin-lyase
CN111454934B (zh) * 2020-04-10 2021-11-30 台州学院 一种edds裂合酶固定化酶的制备方法和应用
WO2024126202A1 (en) * 2022-12-16 2024-06-20 Basf Se New ethylenediamine-n,n'-disuccinic acid (edds) synthases

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS60126092A (ja) * 1983-12-13 1985-07-05 Mitsubishi Petrochem Co Ltd Ｌ−アスパラギン酸の製造法
DE69010526T2 (de) * 1989-02-06 1994-12-08 Mitsubishi Petrochemical Co Verfahren zur Herstellung von L-Alanin.
US5707836A (en) * 1995-03-10 1998-01-13 Nitto Chemical Industry Co., Ltd. Production of alkylene or phenylenediamine disuccinic acid from fumaric acid and a diamine using lyase from microbes
EP0805211B1 (de) * 1996-04-30 2002-10-02 Mitsubishi Rayon Co., Ltd. Verfahren zur Herstellung von optisch-aktiven Aminopolycarbonsäuren
JP3370545B2 (ja) * 1996-11-29 2003-01-27 三菱レイヨン株式会社 エチレンジアミン−ｎ，ｎ’−ジコハク酸：エチレンジアミンリアーゼ活性を有するタンパク質およびその遺伝子

Also Published As

Publication number Publication date
EP0927762A3 (de) 2000-01-19
US6103508A (en) 2000-08-15
DE69820975T2 (de) 2005-01-27
EP0927762B1 (de) 2004-01-07
EP0927762A2 (de) 1999-07-07

Similar Documents

Publication Publication Date Title
DE69133342D1 (de) Rekombinante DNS-Sequenzen kodierend für Enzyme frei von Feedback-Inhibition, Plasmide, die diese Sequenzen enthalten, transformierte Mikroorganismen, nützlich für Produktion aromatischer Aminosäuren, und deren Verfahren zur Herstellung durch Fermentation
DE59611412D1 (de) Verfahren zur mikrobiellen herstellung von aminosäuren durch gesteigerte aktivität von exportcarriern
DE59006837D1 (de) Verfahren zur fermentativen Herstellung von Aminosäuren, insbesondere L-Lysin, dafür geeignete Mikroorganismen und rekombinante DNA.
DE69530242D1 (de) Verfahren zur Herstellung von Glutaminsäure durch Fermentation
DE19681532T1 (de) Verfahren zur Herstellung von L-Glutaminsäure durch Fermentation
DE69434148D1 (de) Alkoholdehydrogenase, dafür kodierende DNA, Herstellung und Verfahren zur Herstellung von optisch aktiven Alkoholen
DE19581681T1 (de) Verfahren zum Abtöten von Mikroorganismen
ID17698A (id) Proses untuk memproduksi asam l-glutamat dengan fermentasi
DE69519638D1 (de) Verfahren zur Herstellung von Alpha-Hydroxysäuren oder Alpha-Hydroxyamiden durch Mikroorganismen
DE69535643D1 (de) Verfahren zur fermentativen Herstellung von L-Lysin und L-glutaminsäure
DE69007800D1 (de) Verfahren zur fermentativen Herstellung von L-Arginin.
DE69514889D1 (de) Verfahren zur Herstellung von optisch aktiven 2-Hydroxysäure und 2-Hydroxyamid
DE69011880D1 (de) Verfahren zur Herstellung von L-Aminosäuren durch Fermentation.
DE59505086D1 (de) Verfahren zur Herstellung von optisch aktiven Alkoholen durch catalytische Reduktion der optisch aktiven Carbonsäuren
DE69820975D1 (de) Verfahren zum Entfernen von Fumarase Aktivität, durch diese Verfahren erhältliche Mikroorganismen und Herstellung von optisch aktiven Aminopolycarbonsäuren mit diesen Mikroorganismen
DE68906904D1 (de) Verfahren zur herstellung von optisch aktiven 2-arylalkansaeuren.
DE69012061D1 (de) Verfahren zur herstellung von kohlenstoffsäureestern und katalysator dazu.
ATE135047T1 (de) Verfahren zur herstellung optisch aktiver cyanhydrine durch enzyme
DE69906607D1 (de) Verfahren zur Herstellung von optisch aktiven Chrysanthemumsäure
DE69506900D1 (de) Enzymatisches verfahren zur herstellung von chiralen alpha-tertiären carbonsäureestern
DE59106876D1 (de) Verfahren zur enzymatischen Herstellung optisch aktiver Cyanhydrine.
DE69519799D1 (de) Verfahren zur herstellung von [s,s]-ethylendiamin-n,n'-dibernsteinsäure
DE59206633D1 (de) Biotechnologisches Verfahren zur Herstellung von S-(+)-2,2-Dimethylcyclopropancarboxamid und R-(-)-2,2-Dimethylcyclopropancarbonsäure
ES534817A0 (es) Procedimiento para aislar acidos carboxilicos producidos enzimaticamente, a partir de las soluciones o suspensiones de reaccion
DE69026585D1 (de) Verfahren zur Herstellung von R-(-)-3-Halogeno-1,2-propandiol durch Behandlung mit Mikroorganismen

Legal Events

Date Code Title Description
8364 No opposition during term of opposition