DE69818983D1 - Verfahren zur herstellung optisch aktiver imidazolverbindungen, zwischenprodukte zu ihrer herstellung und verfahren zu ihrer herstellung - Google Patents
Verfahren zur herstellung optisch aktiver imidazolverbindungen, zwischenprodukte zu ihrer herstellung und verfahren zu ihrer herstellungInfo
- Publication number
- DE69818983D1 DE69818983D1 DE69818983T DE69818983T DE69818983D1 DE 69818983 D1 DE69818983 D1 DE 69818983D1 DE 69818983 T DE69818983 T DE 69818983T DE 69818983 T DE69818983 T DE 69818983T DE 69818983 D1 DE69818983 D1 DE 69818983D1
- Authority
- DE
- Germany
- Prior art keywords
- producing
- optically active
- compound
- intermediate products
- imidazole compounds
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
- C07D233/60—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms with hydrocarbon radicals, substituted by oxygen or sulfur atoms, attached to ring nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4164—1,3-Diazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
- C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
- C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Diabetes (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Endocrinology (AREA)
- Emergency Medicine (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Plural Heterocyclic Compounds (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP1011497 | 1997-01-23 | ||
| JP09010114A JP2000290259A (ja) | 1997-01-23 | 1997-01-23 | 光学活性なイミダゾール化合物の製造方法およびその合成中間体 |
| PCT/JP1998/000150 WO1998032740A1 (fr) | 1997-01-23 | 1998-01-14 | Procede de production de composes d'imidazol opto-actifs, intermediaires aux fins de la synthese de ces composes et leur procede de production |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DE69818983D1 true DE69818983D1 (de) | 2003-11-20 |
| DE69818983T2 DE69818983T2 (de) | 2004-09-09 |
Family
ID=11741291
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE69818983T Expired - Fee Related DE69818983T2 (de) | 1997-01-23 | 1998-01-14 | Verfahren zur herstellung optisch aktiver imidazolverbindungen, zwischenprodukte zu ihrer herstellung und verfahren zu ihrer herstellung |
| DE69835705T Expired - Lifetime DE69835705D1 (de) | 1997-01-23 | 1998-01-14 | Verfahren zur Herstellung von optisch aktiven Imidazolverbindungen, Zwischenprodukte zu deren Herstellung und ihre Herstellung |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE69835705T Expired - Lifetime DE69835705D1 (de) | 1997-01-23 | 1998-01-14 | Verfahren zur Herstellung von optisch aktiven Imidazolverbindungen, Zwischenprodukte zu deren Herstellung und ihre Herstellung |
Country Status (11)
| Country | Link |
|---|---|
| US (2) | US6066739A (de) |
| EP (2) | EP1378507B1 (de) |
| JP (1) | JP2000290259A (de) |
| KR (1) | KR100490891B1 (de) |
| CN (1) | CN1133623C (de) |
| AT (2) | ATE252085T1 (de) |
| AU (1) | AU5496698A (de) |
| CA (1) | CA2278509C (de) |
| DE (2) | DE69818983T2 (de) |
| ES (1) | ES2209104T3 (de) |
| WO (1) | WO1998032740A1 (de) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2000290259A (ja) * | 1997-01-23 | 2000-10-17 | Welfide Corp | 光学活性なイミダゾール化合物の製造方法およびその合成中間体 |
| EP1719764A1 (de) * | 2004-02-27 | 2006-11-08 | Mitsubishi Pharma Corporation | Verfahren zur asymmetrischen reduktion von 4-[5-(imidazol-1-yl)-2-methylbenzoyl]-3,5-dimethylbenzoesäure oder estern davon |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5770884A (en) * | 1980-10-21 | 1982-05-01 | Kyowa Hakko Kogyo Co Ltd | Novel piperidine derivative and its preparation |
| JPS6314771A (ja) * | 1986-07-08 | 1988-01-21 | Sankyo Co Ltd | 光学活性イミダゾ−ル誘導体およびその製法 |
| JPH02215771A (ja) * | 1989-02-14 | 1990-08-28 | Yoshitomi Pharmaceut Ind Ltd | 光学活性なイミダゾール化合物の製造方法およびその合成中間体 |
| US5656762A (en) * | 1990-12-28 | 1997-08-12 | Neurogen Corporation | 4-piperidino-and piperazinomethyl-2-phenylimidazole derivatives, dopamine receptor subtype specific ligands |
| JP2000290259A (ja) * | 1997-01-23 | 2000-10-17 | Welfide Corp | 光学活性なイミダゾール化合物の製造方法およびその合成中間体 |
-
1997
- 1997-01-23 JP JP09010114A patent/JP2000290259A/ja active Pending
-
1998
- 1998-01-14 DE DE69818983T patent/DE69818983T2/de not_active Expired - Fee Related
- 1998-01-14 AT AT98900397T patent/ATE252085T1/de not_active IP Right Cessation
- 1998-01-14 US US09/355,096 patent/US6066739A/en not_active Expired - Fee Related
- 1998-01-14 AT AT03022830T patent/ATE337306T1/de not_active IP Right Cessation
- 1998-01-14 CN CNB988035235A patent/CN1133623C/zh not_active Expired - Fee Related
- 1998-01-14 ES ES98900397T patent/ES2209104T3/es not_active Expired - Lifetime
- 1998-01-14 EP EP03022830A patent/EP1378507B1/de not_active Expired - Lifetime
- 1998-01-14 DE DE69835705T patent/DE69835705D1/de not_active Expired - Lifetime
- 1998-01-14 CA CA002278509A patent/CA2278509C/en not_active Expired - Fee Related
- 1998-01-14 WO PCT/JP1998/000150 patent/WO1998032740A1/ja active IP Right Grant
- 1998-01-14 AU AU54966/98A patent/AU5496698A/en not_active Abandoned
- 1998-01-14 EP EP98900397A patent/EP0972768B1/de not_active Expired - Lifetime
- 1998-01-14 KR KR10-1999-7006595A patent/KR100490891B1/ko not_active IP Right Cessation
-
2000
- 2000-02-23 US US09/511,782 patent/US6166221A/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| WO1998032740A1 (fr) | 1998-07-30 |
| ATE337306T1 (de) | 2006-09-15 |
| CA2278509A1 (en) | 1998-07-30 |
| EP0972768B1 (de) | 2003-10-15 |
| EP1378507B1 (de) | 2006-08-23 |
| JP2000290259A (ja) | 2000-10-17 |
| ES2209104T3 (es) | 2004-06-16 |
| EP0972768A1 (de) | 2000-01-19 |
| DE69835705D1 (de) | 2006-10-05 |
| EP0972768A4 (de) | 2001-06-27 |
| KR20000070362A (ko) | 2000-11-25 |
| CN1133623C (zh) | 2004-01-07 |
| US6166221A (en) | 2000-12-26 |
| AU5496698A (en) | 1998-08-18 |
| CN1251093A (zh) | 2000-04-19 |
| EP1378507A3 (de) | 2004-02-04 |
| CA2278509C (en) | 2007-03-20 |
| US6066739A (en) | 2000-05-23 |
| ATE252085T1 (de) | 2003-11-15 |
| DE69818983T2 (de) | 2004-09-09 |
| EP1378507A2 (de) | 2004-01-07 |
| KR100490891B1 (ko) | 2005-05-24 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CY1112350T1 (el) | Διαδικασια παραγωγης ενος οπτικα ενεργου οξοεπτενοϊκου οξινου εστερα | |
| ATE157647T1 (de) | Verfahren zur herstellung von alpha- ketoamidderivaten | |
| DE69818983D1 (de) | Verfahren zur herstellung optisch aktiver imidazolverbindungen, zwischenprodukte zu ihrer herstellung und verfahren zu ihrer herstellung | |
| ATE252594T1 (de) | Verfahren zur herstellung von ribavirin | |
| EP0937703A4 (de) | Verfahren zur reinigung von brenztraubensäureverbindungen | |
| EP1460065A4 (de) | Verfahren zur herstellung von cyclischen diaminverbindungen bzw. deren salzen | |
| DE69622862D1 (de) | Verfahren zur herstellung von zyklischen verbindungen | |
| ATE201410T1 (de) | Verfahren zur herstellung von 1-(4,5-dihydro)2- thiazolyl-3-azetidinthiolderivaten | |
| DE60232308D1 (de) | Verfahren zur herstellung von fluorinverbindungen | |
| DE50209490D1 (de) | Verfahren zur herstellung von zolpidem | |
| ATE411978T1 (de) | Verfahren zur herstellung von alpha-aminoketonen | |
| HU208525B (en) | Direct process for producing captopril | |
| DE69629661D1 (de) | VERFAHREN ZUR HERSTELLUNG VON N-(D-alpha-METHYL-beta-MERCAPTOPROPIONYL)-L-PROLIN UND INTERMEDIATEN DAVON | |
| ATE460383T1 (de) | Verfahren zur herstellung von stickstofftrifluorid | |
| ATE236909T1 (de) | Verfahren zur herstellung von phosphorohalidaten | |
| DE50101761D1 (de) | Verfahren zur herstellung von 6-(4-chlorphenyl)-2,2-dimethyl-7-phenyl-2,3-dihydro-1h-pyrrolizin-5-yl-essigsäure | |
| DE60239793D1 (de) | Verfahren zur herstellung von 7-chinolinyl-3,5-dihydroxyhept-6-enoat | |
| ATE425972T1 (de) | Verfahren zur herstellung substituierter imidazolderivate und in dem verfahren verwendete zwischenprodukte | |
| ATE555089T1 (de) | Verfahren zur herstellung von -ketoacetalen | |
| ATE179417T1 (de) | Glyceraldehyd-3-pentanid und verfahren zu ihrer herstellung | |
| CA2185956A1 (en) | Method of Purifying 1,3-Bis(3-Aminopropyl)-1,1,3,3-Tetraorganodisiloxane | |
| ATE341642T1 (de) | Verfahren zur herstellung von d- asparaginderivaten | |
| EP1489066A4 (de) | Verfahren zur herstellung von optisch aktiver carbonsäure | |
| JPS6445336A (en) | Production of 2-(r)-hydroxy-4-phenyllactic acid derivative |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 8364 | No opposition during term of opposition | ||
| 8339 | Ceased/non-payment of the annual fee |