DE69812941T2 - Verwendung von mikropartikeln mit adsorbiertem antigen zur stimulierung der immunabwehr - Google Patents
Verwendung von mikropartikeln mit adsorbiertem antigen zur stimulierung der immunabwehr Download PDFInfo
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- DE69812941T2 DE69812941T2 DE69812941T DE69812941T DE69812941T2 DE 69812941 T2 DE69812941 T2 DE 69812941T2 DE 69812941 T DE69812941 T DE 69812941T DE 69812941 T DE69812941 T DE 69812941T DE 69812941 T2 DE69812941 T2 DE 69812941T2
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/16011—Herpesviridae
- C12N2710/16611—Simplexvirus, e.g. human herpesvirus 1, 2
- C12N2710/16634—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2740/00—Reverse transcribing RNA viruses
- C12N2740/00011—Details
- C12N2740/10011—Retroviridae
- C12N2740/16011—Human Immunodeficiency Virus, HIV
- C12N2740/16211—Human Immunodeficiency Virus, HIV concerning HIV gagpol
- C12N2740/16234—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
- C12N2760/00011—Details
- C12N2760/16011—Orthomyxoviridae
- C12N2760/16111—Influenzavirus A, i.e. influenza A virus
- C12N2760/16134—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Virology (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Immunology (AREA)
- Epidemiology (AREA)
- Mycology (AREA)
- Microbiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Communicable Diseases (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pulmonology (AREA)
- Oncology (AREA)
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Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US3631697P | 1997-01-30 | 1997-01-30 | |
| US36316P | 1997-01-30 | ||
| US6974997P | 1997-12-16 | 1997-12-16 | |
| US69749P | 1997-12-16 | ||
| PCT/US1998/001738 WO1998033487A1 (en) | 1997-01-30 | 1998-01-29 | Use of microparticles with adsorbed antigen to stimulate immune responses |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DE69812941D1 DE69812941D1 (de) | 2003-05-15 |
| DE69812941T2 true DE69812941T2 (de) | 2004-02-05 |
Family
ID=26713053
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE69812941T Expired - Lifetime DE69812941T2 (de) | 1997-01-30 | 1998-01-29 | Verwendung von mikropartikeln mit adsorbiertem antigen zur stimulierung der immunabwehr |
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| Country | Link |
|---|---|
| US (2) | US7597908B2 (enExample) |
| EP (1) | EP0991403B1 (enExample) |
| JP (2) | JP5037747B2 (enExample) |
| AT (1) | ATE235890T1 (enExample) |
| AU (1) | AU747577B2 (enExample) |
| CA (1) | CA2279204C (enExample) |
| DE (1) | DE69812941T2 (enExample) |
| DK (1) | DK0991403T3 (enExample) |
| ES (1) | ES2195317T3 (enExample) |
| NZ (1) | NZ337054A (enExample) |
| PT (1) | PT991403E (enExample) |
| WO (1) | WO1998033487A1 (enExample) |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| JPH08507088A (ja) | 1993-12-23 | 1996-07-30 | ゲーエフエフ | 免疫応答の増強方法 |
| JP5037747B2 (ja) | 1997-01-30 | 2012-10-03 | ノバルティス バクシンズ アンド ダイアグノスティックス，インコーポレーテッド | 免疫応答を刺激するための吸着された抗原を有するマイクロパーティクルの使用 |
| US6884435B1 (en) * | 1997-01-30 | 2005-04-26 | Chiron Corporation | Microparticles with adsorbent surfaces, methods of making same, and uses thereof |
| US20040202680A1 (en) * | 1997-01-30 | 2004-10-14 | O'hagan Derek | Microparticles with adsorbent surfaces, methods of making same, and uses thereof |
| US6433040B1 (en) | 1997-09-29 | 2002-08-13 | Inhale Therapeutic Systems, Inc. | Stabilized bioactive preparations and methods of use |
| US6565885B1 (en) | 1997-09-29 | 2003-05-20 | Inhale Therapeutic Systems, Inc. | Methods of spray drying pharmaceutical compositions |
| US20060165606A1 (en) | 1997-09-29 | 2006-07-27 | Nektar Therapeutics | Pulmonary delivery particles comprising water insoluble or crystalline active agents |
| US6309623B1 (en) | 1997-09-29 | 2001-10-30 | Inhale Therapeutic Systems, Inc. | Stabilized preparations for use in metered dose inhalers |
| US6946117B1 (en) | 1997-09-29 | 2005-09-20 | Nektar Therapeutics | Stabilized preparations for use in nebulizers |
| DE69930642T2 (de) * | 1998-07-29 | 2006-12-28 | Chiron Corp., Emeryville | Mikropartikel mit adsorbenten oberflächen, verfahren zu ihrer herstellung und ihrer verwendung |
| US8206749B1 (en) * | 1999-02-26 | 2012-06-26 | Novartis Vaccines And Diagnostics, Inc. | Microemulsions with adsorbed macromolecules and microparticles |
| JP2002538195A (ja) * | 1999-03-08 | 2002-11-12 | パウダージェクト リサーチ リミテッド | 生物活性化合物の持続放出用の無針注射器を使用する微粒子製剤の送達 |
| US7713739B1 (en) | 2000-11-17 | 2010-05-11 | Novartis Vaccines And Diagnostics, Inc. | Microparticle-based transfection and activation of dendritic cells |
| GB0000001D0 (en) * | 2000-01-05 | 2000-02-23 | Du Pont Uk | Pharmaceutical compositions and their preparation |
| US20030129251A1 (en) * | 2000-03-10 | 2003-07-10 | Gary Van Nest | Biodegradable immunomodulatory formulations and methods for use thereof |
| GB0006770D0 (en) * | 2000-03-22 | 2000-05-10 | Secr Defence | Vaccine composition |
| PT1280520E (pt) | 2000-05-10 | 2014-12-16 | Novartis Ag | Pós à base de fosfolípidos para administração de fármacos |
| US7871598B1 (en) | 2000-05-10 | 2011-01-18 | Novartis Ag | Stable metal ion-lipid powdered pharmaceutical compositions for drug delivery and methods of use |
| US20040022814A1 (en) * | 2000-06-15 | 2004-02-05 | O'hagan Derek | Microparticles with adsorbent surfaces, methods of making same, and uses thereof |
| AUPR011700A0 (en) * | 2000-09-14 | 2000-10-05 | Austin Research Institute, The | Composition comprising immunogenic virus sized particles (VSP) |
| US6753015B2 (en) | 2000-09-28 | 2004-06-22 | Chiron Corporation | Microparticle compositions and methods for the manufacture thereof |
| EP1322287B1 (en) * | 2000-09-28 | 2006-03-22 | Chiron Corporation | Microparticles for delivery of the heterologous nucleic acids |
| US6887857B2 (en) | 2001-04-27 | 2005-05-03 | Scimed Life Systems, Inc. | Microparticle protection of therapeutic agents |
| DE10125731A1 (de) * | 2001-05-17 | 2003-03-06 | A I D Autoimmun Diagnostika Gm | Darreichungsform von immunologischen Wirkstoffen |
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| WO2003053411A1 (en) | 2001-12-19 | 2003-07-03 | Nektar Therapeutics | Pulmonary delivery of aminoglycosides |
| EP2572707A3 (en) | 2002-02-20 | 2013-11-06 | Novartis Vaccines and Diagnostics, Inc. | Microparticles with adsorbed polypeptide-containing molecules |
| GB0220194D0 (en) | 2002-08-30 | 2002-10-09 | Chiron Spa | Improved vesicles |
| AU2003282498A1 (en) | 2002-10-07 | 2004-05-04 | Chiron Corporation | Hiv vaccine formulations |
| WO2004046177A2 (en) | 2002-11-15 | 2004-06-03 | Chiron Srl | Unexpected surface proteins in neisseria meningitidis |
| GB0227346D0 (en) | 2002-11-22 | 2002-12-31 | Chiron Spa | 741 |
| WO2004060396A2 (en) | 2002-12-27 | 2004-07-22 | Chiron Corporation | Immunogenic compositions containing phospholpid |
| US7731967B2 (en) | 2003-04-30 | 2010-06-08 | Novartis Vaccines And Diagnostics, Inc. | Compositions for inducing immune responses |
| CA2528007C (en) | 2003-06-02 | 2012-03-27 | Chiron Corporation | Immunogenic compositions based on microparticles comprising adsorbed toxoid and a polysaccharide-containing antigen |
| FR2859909B1 (fr) * | 2003-09-22 | 2007-09-07 | Biomerieux Sa | Procede de preparation de microparticules bioresorbables, microparticules obtenues et utilisation |
| EP1812056B1 (en) | 2004-11-15 | 2013-08-07 | Novartis Vaccines and Diagnostics, Inc. | Immunogenic compositions containing anthrax antigen, biodegradable polymer microparticles, and polynucleotide-containing immunological adjuvant |
| NZ568211A (en) | 2005-11-04 | 2011-11-25 | Novartis Vaccines & Diagnostic | Influenza vaccines including combinations of particulate adjuvants and immunopotentiators |
| FR2893254B1 (fr) * | 2005-11-14 | 2007-12-21 | Biomerieux Sa | Composition comprenant un vecteur synthetique colloidal bioresorbable et un vecteur viral et son utilisation prophylactique, therapeutique et diagnostique. |
| AU2007221154A1 (en) | 2006-02-24 | 2007-09-07 | Novartis Ag | Microparticles containing biodegradable polymer and cationic polysaccharide for use in immunogenic compositions |
| ES2664753T3 (es) | 2007-12-07 | 2018-04-23 | Glaxosmithkline Biologicals Sa | Composiciones de inducción de respuestas inmunes |
| KR20130121699A (ko) | 2010-05-28 | 2013-11-06 | 테트리스 온라인, 인코포레이티드 | 상호작용 혼성 비동기 컴퓨터 게임 기반구조 |
| US9655845B2 (en) | 2011-07-06 | 2017-05-23 | Glaxosmithkline Biologicals, S.A. | Oil-in-water emulsions that contain nucleic acids |
| AU2012280904B2 (en) | 2011-07-06 | 2017-02-23 | Glaxosmithkline Biologicals S.A. | Cationic oil-in-water emulsions |
| EP3329936B1 (en) | 2011-08-22 | 2025-03-19 | BlueWillow Biologics, Inc. | Herpes simplex virus nanoemulsion vaccine |
| WO2013049106A2 (en) | 2011-09-26 | 2013-04-04 | Wustenberg William | Reduction of implant infection via tunable stimulation of localized adaptive immune response |
| US12220486B2 (en) | 2018-03-02 | 2025-02-11 | Saint Joseph's University | Polymer compositions for storage and release of polypeptides |
| EP3581201A1 (en) | 2018-06-15 | 2019-12-18 | GlaxoSmithKline Biologicals S.A. | Escherichia coli o157:h7 proteins and uses thereof |
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| ATE155813T1 (de) * | 1989-05-19 | 1997-08-15 | Genentech Inc | Her2 extrazellulare domäne |
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| US20040022814A1 (en) * | 2000-06-15 | 2004-02-05 | O'hagan Derek | Microparticles with adsorbent surfaces, methods of making same, and uses thereof |
| US6753015B2 (en) * | 2000-09-28 | 2004-06-22 | Chiron Corporation | Microparticle compositions and methods for the manufacture thereof |
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-
1998
- 1998-01-29 JP JP53306798A patent/JP5037747B2/ja not_active Expired - Fee Related
- 1998-01-29 DE DE69812941T patent/DE69812941T2/de not_active Expired - Lifetime
- 1998-01-29 AU AU62557/98A patent/AU747577B2/en not_active Ceased
- 1998-01-29 PT PT98904760T patent/PT991403E/pt unknown
- 1998-01-29 WO PCT/US1998/001738 patent/WO1998033487A1/en not_active Ceased
- 1998-01-29 CA CA002279204A patent/CA2279204C/en not_active Expired - Fee Related
- 1998-01-29 AT AT98904760T patent/ATE235890T1/de active
- 1998-01-29 DK DK98904760T patent/DK0991403T3/da active
- 1998-01-29 NZ NZ337054A patent/NZ337054A/xx not_active IP Right Cessation
- 1998-01-29 EP EP98904760A patent/EP0991403B1/en not_active Expired - Lifetime
- 1998-01-29 ES ES98904760T patent/ES2195317T3/es not_active Expired - Lifetime
-
2002
- 2002-07-03 US US10/189,104 patent/US7597908B2/en not_active Expired - Fee Related
-
2008
- 2008-12-02 JP JP2008308030A patent/JP2009102338A/ja not_active Withdrawn
-
2009
- 2009-10-06 US US12/573,903 patent/US20100021548A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| EP0991403A1 (en) | 2000-04-12 |
| AU747577B2 (en) | 2002-05-16 |
| US20100021548A1 (en) | 2010-01-28 |
| CA2279204A1 (en) | 1998-08-06 |
| DE69812941D1 (de) | 2003-05-15 |
| WO1998033487A1 (en) | 1998-08-06 |
| JP5037747B2 (ja) | 2012-10-03 |
| JP2009102338A (ja) | 2009-05-14 |
| HK1023507A1 (en) | 2000-09-15 |
| AU6255798A (en) | 1998-08-25 |
| US20030049298A1 (en) | 2003-03-13 |
| DK0991403T3 (da) | 2003-07-28 |
| JP2001511148A (ja) | 2001-08-07 |
| US7597908B2 (en) | 2009-10-06 |
| CA2279204C (en) | 2005-11-15 |
| PT991403E (pt) | 2003-08-29 |
| NZ337054A (en) | 2001-03-30 |
| ATE235890T1 (de) | 2003-04-15 |
| ES2195317T3 (es) | 2003-12-01 |
| EP0991403B1 (en) | 2003-04-02 |
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Owner name: NOVARTIS VACCINES AND DIAGNOSTICS,INC.(N.D.GES, US |