DE69806747T2 - Verfahren zur veresterung von aminosäuren und proteinen - Google Patents
Verfahren zur veresterung von aminosäuren und proteinenInfo
- Publication number
- DE69806747T2 DE69806747T2 DE69806747T DE69806747T DE69806747T2 DE 69806747 T2 DE69806747 T2 DE 69806747T2 DE 69806747 T DE69806747 T DE 69806747T DE 69806747 T DE69806747 T DE 69806747T DE 69806747 T2 DE69806747 T2 DE 69806747T2
- Authority
- DE
- Germany
- Prior art keywords
- esterification
- proteins
- amino acids
- acids
- amino
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06008—Dipeptides with the first amino acid being neutral
- C07K5/06017—Dipeptides with the first amino acid being neutral and aliphatic
- C07K5/06026—Dipeptides with the first amino acid being neutral and aliphatic the side chain containing 0 or 1 carbon atom, i.e. Gly or Ala
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C227/00—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C227/14—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton from compounds containing already amino and carboxyl groups or derivatives thereof
- C07C227/18—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton from compounds containing already amino and carboxyl groups or derivatives thereof by reactions involving amino or carboxyl groups, e.g. hydrolysis of esters or amides, by formation of halides, salts or esters
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C305/00—Esters of sulfuric acids
- C07C305/02—Esters of sulfuric acids having oxygen atoms of sulfate groups bound to acyclic carbon atoms of a carbon skeleton
- C07C305/04—Esters of sulfuric acids having oxygen atoms of sulfate groups bound to acyclic carbon atoms of a carbon skeleton being acyclic and saturated
- C07C305/06—Hydrogenosulfates
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D207/10—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D207/16—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/107—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06104—Dipeptides with the first amino acid being acidic
- C07K5/06113—Asp- or Asn-amino acid
- C07K5/06121—Asp- or Asn-amino acid the second amino acid being aromatic or cycloaliphatic
- C07K5/0613—Aspartame
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biophysics (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Medicinal Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Analytical Chemistry (AREA)
- Peptides Or Proteins (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
NL1005901A NL1005901C2 (nl) | 1997-04-25 | 1997-04-25 | Werkwijze voor de verestering van aminozuren en peptiden. |
PCT/NL1998/000227 WO1998049133A1 (en) | 1997-04-25 | 1998-04-23 | Process for esterification of amino acids and peptides |
Publications (2)
Publication Number | Publication Date |
---|---|
DE69806747D1 DE69806747D1 (de) | 2002-08-29 |
DE69806747T2 true DE69806747T2 (de) | 2003-03-06 |
Family
ID=19764855
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69806747T Expired - Fee Related DE69806747T2 (de) | 1997-04-25 | 1998-04-23 | Verfahren zur veresterung von aminosäuren und proteinen |
Country Status (8)
Country | Link |
---|---|
US (1) | US6222013B1 (de) |
EP (1) | EP0977726B1 (de) |
JP (1) | JP2001524107A (de) |
AU (1) | AU7085398A (de) |
DE (1) | DE69806747T2 (de) |
ES (1) | ES2178204T3 (de) |
NL (1) | NL1005901C2 (de) |
WO (1) | WO1998049133A1 (de) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2007045470A1 (en) * | 2005-10-20 | 2007-04-26 | Dsm Ip Assets B.V. | Enzymatic conversion of oligopeptide amides to oligopeptide alkylesters |
CN102216324B (zh) * | 2008-11-19 | 2014-02-12 | 帝斯曼知识产权资产管理有限公司 | 使用酶促反应和偶联反应的肽合成 |
WO2011113486A1 (en) | 2010-03-17 | 2011-09-22 | Deretil, S.A. | Process for the synthesis of hydroxyphenylglycine esters |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2501677A1 (fr) * | 1981-03-11 | 1982-09-17 | Flork Michel | Nouveau procede d'esterification d'amino-acides |
PL159729B1 (pl) * | 1989-04-10 | 1993-01-29 | Sposób wytwarzania estru metylowego kwasu 3-aminopirazynokarboksylowego-2 PL | |
JPH05148199A (ja) * | 1991-11-28 | 1993-06-15 | Ajinomoto Co Inc | アミノ酸エステルの製造法 |
-
1997
- 1997-04-25 NL NL1005901A patent/NL1005901C2/nl not_active IP Right Cessation
-
1998
- 1998-04-23 EP EP98917795A patent/EP0977726B1/de not_active Expired - Lifetime
- 1998-04-23 AU AU70853/98A patent/AU7085398A/en not_active Abandoned
- 1998-04-23 JP JP54684798A patent/JP2001524107A/ja not_active Withdrawn
- 1998-04-23 DE DE69806747T patent/DE69806747T2/de not_active Expired - Fee Related
- 1998-04-23 ES ES98917795T patent/ES2178204T3/es not_active Expired - Lifetime
- 1998-04-23 WO PCT/NL1998/000227 patent/WO1998049133A1/en active IP Right Grant
-
1999
- 1999-10-25 US US09/425,023 patent/US6222013B1/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
NL1005901C2 (nl) | 1998-10-27 |
EP0977726B1 (de) | 2002-07-24 |
AU7085398A (en) | 1998-11-24 |
JP2001524107A (ja) | 2001-11-27 |
ES2178204T3 (es) | 2002-12-16 |
EP0977726A1 (de) | 2000-02-09 |
DE69806747D1 (de) | 2002-08-29 |
WO1998049133A1 (en) | 1998-11-05 |
US6222013B1 (en) | 2001-04-24 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition | ||
8327 | Change in the person/name/address of the patent owner |
Owner name: DSM IP ASSETS B.V., HEERLEN, NL |
|
8339 | Ceased/non-payment of the annual fee |