DE69728802D1 - Wirkstoffimmobilisierte Partikel und Verfahren zur Reinigung von Proteinen - Google Patents

Wirkstoffimmobilisierte Partikel und Verfahren zur Reinigung von Proteinen

Info

Publication number
DE69728802D1
DE69728802D1 DE69728802T DE69728802T DE69728802D1 DE 69728802 D1 DE69728802 D1 DE 69728802D1 DE 69728802 T DE69728802 T DE 69728802T DE 69728802 T DE69728802 T DE 69728802T DE 69728802 D1 DE69728802 D1 DE 69728802D1
Authority
DE
Germany
Prior art keywords
particle
protein purification
immobilized particles
immobilized
particles
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69728802T
Other languages
English (en)
Other versions
DE69728802T2 (de
Inventor
Hiroshi Handa
Haruma Kawaguchi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Application granted granted Critical
Publication of DE69728802D1 publication Critical patent/DE69728802D1/de
Publication of DE69728802T2 publication Critical patent/DE69728802T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54313—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54353—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals with ligand attached to the carrier via a chemical coupling agent
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/94—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving narcotics or drugs or pharmaceuticals, neurotransmitters or associated receptors
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/803—Physical recovery methods, e.g. chromatography, grinding
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/814—Enzyme separation or purification
    • Y10S435/815—Enzyme separation or purification by sorption
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/81—Carrier - bound or immobilized peptides or proteins and the preparation thereof, e.g. biological cell or cell fragment as carrier
    • Y10S530/812—Peptides or proteins is immobilized on, or in, an organic carrier
    • Y10S530/815—Carrier is a synthetic polymer
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/81—Carrier - bound or immobilized peptides or proteins and the preparation thereof, e.g. biological cell or cell fragment as carrier
    • Y10S530/812—Peptides or proteins is immobilized on, or in, an organic carrier
    • Y10S530/815—Carrier is a synthetic polymer
    • Y10S530/816—Attached to the carrier via a bridging agent

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Cell Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Biotechnology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biophysics (AREA)
  • Zoology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Toxicology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Peptides Or Proteins (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
DE69728802T 1996-02-05 1997-02-05 Wirkstoffimmobilisierte Partikel und Verfahren zur Reinigung von Proteinen Expired - Lifetime DE69728802T2 (de)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
JP1882796 1996-02-05
JP1882796 1996-02-05
JP26671196 1996-09-17
JP26671196 1996-09-17

Publications (2)

Publication Number Publication Date
DE69728802D1 true DE69728802D1 (de) 2004-06-03
DE69728802T2 DE69728802T2 (de) 2005-03-31

Family

ID=26355561

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69728802T Expired - Lifetime DE69728802T2 (de) 1996-02-05 1997-02-05 Wirkstoffimmobilisierte Partikel und Verfahren zur Reinigung von Proteinen

Country Status (4)

Country Link
US (2) US5986072A (de)
EP (1) EP0787988B1 (de)
JP (1) JP2000351814A (de)
DE (1) DE69728802T2 (de)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6545132B1 (en) * 1996-02-05 2003-04-08 Hiroshi Handa Microsphere containing glycidyl methacrylate covered polymer and spacer coupled compound for isolating substances
US6703207B2 (en) * 1996-02-05 2004-03-09 Hiroshi Handa Method of screening substances with a glycidyl methacrylate covered styrene-glycidyl methacrylate polymer
US6342561B1 (en) * 1999-11-17 2002-01-29 3M Innovative Properties Company Organic particulate-filled adhesive
US7732404B2 (en) 1999-12-30 2010-06-08 Dexcel Ltd Pro-nanodispersion for the delivery of cyclosporin
US20040115726A1 (en) * 2001-09-14 2004-06-17 Renpei Nagashima Method, system, apparatus and device for discovering and preparing chemical compounds for medical and other uses.
KR20070058463A (ko) * 2004-08-30 2007-06-08 도레이 가부시끼가이샤 분획 장치
JP2006131771A (ja) * 2004-11-05 2006-05-25 Tokyo Institute Of Technology ポリマー被覆磁性ビーズおよびその製造方法
DE602006012040D1 (de) 2005-11-01 2010-03-18 Jsr Corp Organische Polymerpartikel und Herstellungsverfahren dafür, magnetische Partikel zur Diagnose, Partikel mit einer Carboxylgruppe und Herstellungsverfahren dafür sowie sondengebundene Partikel und Herstellungsverfahren dafür
JP2009292804A (ja) * 2007-11-28 2009-12-17 Canon Inc リガンド分子固定ポリマー、リガンド分子固定粒子、標的物質の検出方法および標的物質の分離方法
EP2697645A1 (de) * 2011-04-15 2014-02-19 VivaBioCell SpA Immundiagnostisches verfahren zur diagnose der autoimmunerkrankungen systemische sklerose (ssc) und systemischer lupus erythematodes (sle)
WO2015119288A1 (ja) 2014-02-10 2015-08-13 Jsr株式会社 標的物質捕獲方法、標的物質捕獲用の固相担体及び当該固相担体の製造方法
JP7406327B2 (ja) 2019-08-23 2023-12-27 キヤノン株式会社 粒子、凝集法用粒子、及び、これを含む試薬、キット、並びに検出方法
JP7384594B2 (ja) * 2019-08-23 2023-11-21 キヤノン株式会社 粒子、アフィニティー粒子、及び、これを含む試薬、キット、並びに検出方法
EP4023682A4 (de) 2019-08-30 2023-11-08 Canon Kabushiki Kaisha Partikel, affinitätspartikel mit ligand für zielsubstanz, in-vitro-diagnostisches reagenz und kit damit und verfahren zum nachweis einer zielsubstanz
JP7399675B2 (ja) * 2019-10-25 2023-12-18 キヤノン株式会社 粒子およびその製造方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6317692A (ja) * 1986-07-09 1988-01-25 Japanese Res & Dev Assoc Bio Reactor Syst Food Ind マルトオリゴ糖生成アミラ−ゼの固定化方法
JP2739068B2 (ja) * 1988-09-24 1998-04-08 春馬 川口 Ｄｎａ固定ミクロスフェア及びそれを用いるｄｎａ転写制御因子精製法
JP2753762B2 (ja) * 1990-06-08 1998-05-20 春馬 川口 Ｄｎａ固定ミクロスフェア及びそれを用いるｄｎａ転写制御因子精製法
JPH04218772A (ja) * 1991-03-30 1992-08-10 Tokuyama Soda Co Ltd 診断用試薬

Also Published As

Publication number Publication date
DE69728802T2 (de) 2005-03-31
EP0787988A3 (de) 2000-10-04
JP2000351814A (ja) 2000-12-19
US5986072A (en) 1999-11-16
EP0787988A2 (de) 1997-08-06
US20020160472A1 (en) 2002-10-31
EP0787988B1 (de) 2004-04-28

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