DE69804421D1 - Verfahren zur Herstellung von Rhein und seinen Diacylderivaten - Google Patents

Verfahren zur Herstellung von Rhein und seinen Diacylderivaten

Info

Publication number
DE69804421D1
DE69804421D1 DE69804421T DE69804421T DE69804421D1 DE 69804421 D1 DE69804421 D1 DE 69804421D1 DE 69804421 T DE69804421 T DE 69804421T DE 69804421 T DE69804421 T DE 69804421T DE 69804421 D1 DE69804421 D1 DE 69804421D1
Authority
DE
Germany
Prior art keywords
rhine
production
diacyl derivatives
derivatives
rhein
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69804421T
Other languages
English (en)
Other versions
DE69804421T2 (de
Inventor
Napoli Guido Di
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Laboratoire Medidom SA
Original Assignee
Laboratoire Medidom SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Laboratoire Medidom SA filed Critical Laboratoire Medidom SA
Application granted granted Critical
Publication of DE69804421D1 publication Critical patent/DE69804421D1/de
Publication of DE69804421T2 publication Critical patent/DE69804421T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/16—Preparation of carboxylic acids or their salts, halides or anhydrides by oxidation
    • C07C51/27—Preparation of carboxylic acids or their salts, halides or anhydrides by oxidation with oxides of nitrogen or nitrogen-containing mineral acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C67/00—Preparation of carboxylic acid esters
    • C07C67/08—Preparation of carboxylic acid esters by reacting carboxylic acids or symmetrical anhydrides with the hydroxy or O-metal group of organic compounds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2603/00—Systems containing at least three condensed rings
    • C07C2603/02—Ortho- or ortho- and peri-condensed systems
    • C07C2603/04—Ortho- or ortho- and peri-condensed systems containing three rings
    • C07C2603/22—Ortho- or ortho- and peri-condensed systems containing three rings containing only six-membered rings
    • C07C2603/24—Anthracenes; Hydrogenated anthracenes

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
DE69804421T 1997-12-30 1998-12-23 Verfahren zur Herstellung von Rhein und seinen Diacylderivaten Expired - Lifetime DE69804421T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT97MI002899A IT1297038B1 (it) 1997-12-30 1997-12-30 Procedimento per la preparazione di reina e suoi diacilderivati

Publications (2)

Publication Number Publication Date
DE69804421D1 true DE69804421D1 (de) 2002-05-02
DE69804421T2 DE69804421T2 (de) 2002-11-07

Family

ID=11378477

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69804421T Expired - Lifetime DE69804421T2 (de) 1997-12-30 1998-12-23 Verfahren zur Herstellung von Rhein und seinen Diacylderivaten

Country Status (5)

Country Link
EP (1) EP0928781B1 (de)
AT (1) ATE215060T1 (de)
DE (1) DE69804421T2 (de)
ES (1) ES2172857T3 (de)
IT (1) IT1297038B1 (de)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AR026801A1 (es) 2000-01-12 2003-02-26 Medidom Lab Sustancias para uso en el tratamiento de la psoriasis
IT1318574B1 (it) * 2000-06-13 2003-08-27 Synteco Spa Procedimento per la purificazione di diacereina.
EP1666446A1 (de) * 2004-11-12 2006-06-07 Laboratoire Medidom S.A. Verfahren zur Herstellung von Rhein und Diacerhein
CN100351222C (zh) * 2006-02-16 2007-11-28 江阴南极星生物制品有限公司 大黄酸的制备方法
CN101104583B (zh) * 2006-07-13 2010-06-02 上海朴颐化学科技有限公司 两步氧化法制备双醋瑞因的工艺
ITMI20080011A1 (it) * 2008-01-04 2009-07-05 Chimico Internaz S P A Procedimento per la preparazione di diacereina
WO2009106910A1 (en) 2008-02-29 2009-09-03 Laboratoire Medidom S.A. Process for the preparation of aloe-emodin
WO2009106908A1 (en) 2008-02-29 2009-09-03 Laboratoire Medidom S.A. Process for preparing rhein
EP2218707A1 (de) * 2009-02-16 2010-08-18 Evultis S.A. Verfahren zur Herstellung eines nicht genotoxischen Diacetylrheins (Diacerein)
BRPI0917627A2 (pt) * 2008-12-09 2015-11-17 Evultis Sa "processo para produzir diacereína não genotóxica, diacereína não genotíxica, cápsulas e formulações farmacêuticas"
ITTO20110120A1 (it) 2011-02-11 2012-08-12 Icrom Spa Un nuovo processo di purificazione per derivati antrachinonici
CN103360250B (zh) * 2012-03-30 2016-06-01 常州靶点医药科技有限公司 一种高收率的双醋瑞因合成方法
CN103127252B (zh) * 2013-03-13 2015-03-11 四川省中医药科学院 用于男性性功能保健的组合物
CN103694114A (zh) * 2013-12-09 2014-04-02 台州海辰药业有限公司 一种大黄酸的合成方法
CN104262147A (zh) * 2014-08-25 2015-01-07 台州海辰药业有限公司 4,5-二乙酰氧-9,10-二氧-9,10-二氢-2-蒽羧酸的晶型及其制备方法
CN104292101A (zh) * 2014-09-18 2015-01-21 上海慈瑞医药科技有限公司 一种二乙酰大黄酸的制备方法
CN104897839B (zh) * 2015-06-12 2017-02-08 中国人民解放军第三〇二医院 一种多组分综合量化的中药质量评控方法及应用
CN105044300B (zh) * 2015-06-18 2017-07-07 中国人民解放军第三〇二医院 一种基于抗痢疾杆菌效应当量因子调节黄连药材用量的方法
CN110105202B (zh) * 2019-05-16 2021-09-03 北京中医药大学 一种高效、快速分离制备大黄酸衍生物的方法
CN114874171B (zh) * 2022-05-17 2023-05-23 华南理工大学 一种芦荟苷酯及其制备方法与应用

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3678107A (en) * 1969-03-15 1972-07-18 Mitsubishi Edogawa Kagaku Kk Process for the production of oxalic acid
GB1503649A (en) * 1974-06-28 1978-03-15 Glaxo Lab Ltd Process for the preparation of alpha-keto acids
IT1264545B1 (it) * 1993-07-30 1996-10-02 Medidom Lab Procedimento per la preparazione della diacereina

Also Published As

Publication number Publication date
ATE215060T1 (de) 2002-04-15
EP0928781B1 (de) 2002-03-27
DE69804421T2 (de) 2002-11-07
EP0928781A1 (de) 1999-07-14
ITMI972899A1 (it) 1999-06-30
ES2172857T3 (es) 2002-10-01
IT1297038B1 (it) 1999-08-03

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Legal Events

Date Code Title Description
8328 Change in the person/name/address of the agent

Representative=s name: SEITZ, R., DIPL.-ING.UNIV., PAT.-ANW., 80538 MUENC