DE68919282T2 - Verfahren zur Herstellung von Cephalosporin und Zwischenverbindungen. - Google Patents
Verfahren zur Herstellung von Cephalosporin und Zwischenverbindungen.Info
- Publication number
- DE68919282T2 DE68919282T2 DE68919282T DE68919282T DE68919282T2 DE 68919282 T2 DE68919282 T2 DE 68919282T2 DE 68919282 T DE68919282 T DE 68919282T DE 68919282 T DE68919282 T DE 68919282T DE 68919282 T2 DE68919282 T2 DE 68919282T2
- Authority
- DE
- Germany
- Prior art keywords
- cephalosporin
- intermediates
- preparation
- production
- antiobiotics
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/587—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with aliphatic hydrocarbon radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms, said aliphatic radicals being substituted in the alpha-position to the ring by a hetero atom, e.g. with m >= 0, Z being a singly or a doubly bound hetero atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Communicable Diseases (AREA)
- Pharmacology & Pharmacy (AREA)
- Oncology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Cephalosporin Compounds (AREA)
- Thiazole And Isothizaole Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
ES8801910A ES2006988A6 (es) | 1988-06-20 | 1988-06-20 | Procedimiento de preparar hidrocloruro cloruro-2-(2-aminotiazol-4-il)-2-metoxiiminoacetil-sulfito-dimetilformiminio y procedimiento de utilizacion del mismo para obtencion de amidas. |
Publications (2)
Publication Number | Publication Date |
---|---|
DE68919282D1 DE68919282D1 (de) | 1994-12-15 |
DE68919282T2 true DE68919282T2 (de) | 1995-05-24 |
Family
ID=8256891
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE68919282T Expired - Fee Related DE68919282T2 (de) | 1988-06-20 | 1989-06-16 | Verfahren zur Herstellung von Cephalosporin und Zwischenverbindungen. |
Country Status (6)
Country | Link |
---|---|
US (1) | US5037988A (de) |
EP (1) | EP0347777B1 (de) |
JP (1) | JPH0245478A (de) |
AT (1) | ATE113939T1 (de) |
DE (1) | DE68919282T2 (de) |
ES (2) | ES2006988A6 (de) |
Families Citing this family (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB9423459D0 (en) * | 1994-11-21 | 1995-01-11 | Biochemie Gmbh | Silylation process |
AT402928B (de) * | 1994-12-23 | 1997-09-25 | Biochemie Gmbh | Neues verfahren zur herstellung von cefotaxim |
IN181459B (de) * | 1995-12-26 | 1998-06-20 | Lupin Lab Ltd | |
EP0791597B1 (de) * | 1996-02-21 | 2000-07-12 | Lupin Laboratories Limited | Verfahren zur Herstellung von Cephalosporinderivaten und Zwischenverbindungen |
EP0791596A1 (de) * | 1996-02-21 | 1997-08-27 | Lupin Laboratories Limited | Verfahren zur Herstellung von Cephalosporinen und seine Zwischenverbindungen |
US6610845B1 (en) | 2002-01-04 | 2003-08-26 | Orchid Chemicals & Pharmaceuticals Limited, India | Thioester derivatives of thiazolyl acetic acid and their use in the preparation of cephalosporin compounds |
AU2002368505A1 (en) * | 2002-12-26 | 2004-07-22 | Lupin Limited | Novel intermediates for synthesis of cephalosporins and process for preparation of such intermediates |
WO2005076694A2 (en) * | 2004-01-16 | 2005-08-25 | Wockhardt Limited | Improved process for the production of cefotaxime sodium |
CN102702233A (zh) * | 2012-05-18 | 2012-10-03 | 苏州中联化学制药有限公司 | 头孢曲松钠的制备方法 |
CN109503630A (zh) * | 2018-12-14 | 2019-03-22 | 河北合佳医药科技集团股份有限公司 | 一种去乙酰头孢噻肟的制备方法 |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2060460A5 (de) * | 1968-12-21 | 1971-06-18 | Coll Antonio | |
US4871860A (en) * | 1976-04-12 | 1989-10-03 | Fujisawa Pharmaceutical Co., Ltd. | Syn-isomer of 3,7-disubstituted-3-cephem-4-caroxylic acid compounds and processes for the preparation thereof |
FR2462439A1 (fr) * | 1979-07-26 | 1981-02-13 | Roussel Uclaf | Nouveau procede de preparation de produits derives de l'acide 7-/(2-aryl) 2-hydroxyimino acetamido/cephalosporanique |
DE3419015A1 (de) * | 1984-05-22 | 1985-11-28 | Bayer Ag, 5090 Leverkusen | Verfahren zur herstellung von cephalosporinen |
DE3542644A1 (de) * | 1985-12-03 | 1987-06-04 | Hoechst Ag | Verfahren zur herstellung von cefodizim |
-
1988
- 1988-06-20 ES ES8801910A patent/ES2006988A6/es not_active Expired
-
1989
- 1989-06-16 EP EP89111004A patent/EP0347777B1/de not_active Expired - Lifetime
- 1989-06-16 AT AT89111004T patent/ATE113939T1/de not_active IP Right Cessation
- 1989-06-16 DE DE68919282T patent/DE68919282T2/de not_active Expired - Fee Related
- 1989-06-16 ES ES89111004T patent/ES2065944T3/es not_active Expired - Lifetime
- 1989-06-19 US US07/367,656 patent/US5037988A/en not_active Expired - Fee Related
- 1989-06-19 JP JP1158126A patent/JPH0245478A/ja active Pending
Also Published As
Publication number | Publication date |
---|---|
EP0347777B1 (de) | 1994-11-09 |
ES2006988A6 (es) | 1989-05-16 |
DE68919282D1 (de) | 1994-12-15 |
ES2065944T3 (es) | 1995-03-01 |
EP0347777A3 (de) | 1991-08-28 |
EP0347777A2 (de) | 1989-12-27 |
JPH0245478A (ja) | 1990-02-15 |
ATE113939T1 (de) | 1994-11-15 |
US5037988A (en) | 1991-08-06 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition | ||
8339 | Ceased/non-payment of the annual fee |