DE69738656D1 - Cyclosporin enthaltende Präparate - Google Patents

Cyclosporin enthaltende Präparate

Info

Publication number
DE69738656D1
DE69738656D1 DE69738656T DE69738656T DE69738656D1 DE 69738656 D1 DE69738656 D1 DE 69738656D1 DE 69738656 T DE69738656 T DE 69738656T DE 69738656 T DE69738656 T DE 69738656T DE 69738656 D1 DE69738656 D1 DE 69738656D1
Authority
DE
Germany
Prior art keywords
fatty acid
composition
cyclosporin
peg
containing preparations
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69738656T
Other languages
English (en)
Other versions
DE69738656T2 (de
Inventor
Jong Soo Woo
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novartis AG
Original Assignee
Novartis AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from KR1019960022417A external-priority patent/KR0183449B1/ko
Priority claimed from KR1019970008750A external-priority patent/KR19980073479A/ko
Application filed by Novartis AG filed Critical Novartis AG
Application granted granted Critical
Publication of DE69738656D1 publication Critical patent/DE69738656D1/de
Publication of DE69738656T2 publication Critical patent/DE69738656T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4858—Organic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/12—Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
    • A61K38/13—Cyclosporins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
    • A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • A61P33/06—Antimalarials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/10—Anthelmintics
    • A61P33/12—Schistosomicides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
DE69738656T 1996-06-19 1997-06-19 Cyclosporin enthaltende Präparate Expired - Fee Related DE69738656T2 (de)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
KR9622417 1996-06-19
KR1019960022417A KR0183449B1 (ko) 1996-06-19 1996-06-19 사이클로스포린-함유 연질캅셀제
KR1019970008750A KR19980073479A (ko) 1997-03-14 1997-03-14 사이클로스포린-함유 연질캅셀제
KR9708750 1997-03-14

Publications (2)

Publication Number Publication Date
DE69738656D1 true DE69738656D1 (de) 2008-06-05
DE69738656T2 DE69738656T2 (de) 2009-06-04

Family

ID=26631929

Family Applications (2)

Application Number Title Priority Date Filing Date
DE69738656T Expired - Fee Related DE69738656T2 (de) 1996-06-19 1997-06-19 Cyclosporin enthaltende Präparate
DE69731072T Expired - Fee Related DE69731072T2 (de) 1996-06-19 1997-06-19 Cyclosporin enthaltende weichkapselpräparate

Family Applications After (1)

Application Number Title Priority Date Filing Date
DE69731072T Expired - Fee Related DE69731072T2 (de) 1996-06-19 1997-06-19 Cyclosporin enthaltende weichkapselpräparate

Country Status (28)

Country Link
EP (2) EP0869810B1 (de)
JP (2) JP3519414B2 (de)
KR (2) KR20000016761A (de)
CN (2) CN1494920A (de)
AT (2) ATE278412T1 (de)
AU (1) AU719251B2 (de)
BR (2) BR9713811A (de)
CA (2) CA2240705C (de)
CY (1) CY2549B1 (de)
CZ (2) CZ291641B6 (de)
DE (2) DE69738656T2 (de)
DK (1) DK0869810T3 (de)
ES (2) ES2305396T3 (de)
HK (1) HK1010492A1 (de)
HU (1) HUP9801109A3 (de)
IL (5) IL123840A (de)
MX (2) MX9804414A (de)
MY (1) MY117765A (de)
NO (2) NO321921B1 (de)
NZ (1) NZ330062A (de)
PL (1) PL188500B1 (de)
PT (2) PT1413297E (de)
RU (2) RU2181055C2 (de)
SG (1) SG88752A1 (de)
SI (2) SI9720011A (de)
SK (2) SK283361B6 (de)
TR (2) TR199800525T2 (de)
WO (1) WO1997048410A1 (de)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU722285B2 (en) * 1996-06-19 2000-07-27 Novartis Ag Cyclosporin-containing soft capsule preparations
KR19980073479A (ko) * 1997-03-14 1998-11-05 한스루돌프하우스, 니콜케르커 사이클로스포린-함유 연질캅셀제
CZ291641B6 (cs) * 1996-06-19 2003-04-16 Novartis Ag Přípravek obsahující cyklosporin
US6187747B1 (en) 1997-09-08 2001-02-13 Panacea Biotech Limited Pharmaceutical composition comprising cyclosporin
US6346511B1 (en) 1997-09-08 2002-02-12 Panacea Biotec Limited Pharmaceutical composition comprising cyclosporin
US6008191A (en) * 1997-09-08 1999-12-28 Panacea Biotec Limited Pharmaceutical compositions containing cyclosporin
NZ329929A (en) * 1998-03-09 1999-10-28 Bernard Charles Sherman Pharmaceutical emulsion preconcentrate containing cyclosporin in a solvent system containing glycerides, propylene or polyethylene glycol, a surfactant and a co-surfactant
AU2001225459B2 (en) 2000-09-18 2005-12-22 Rpg Life Sciences Limited Selfemulsifiable formulation having enhanced bioabsorption and immunosuppression activities
EP1453544A2 (de) 2001-06-21 2004-09-08 Pfizer Products Inc. Selbstemulgierbare zubereitungen enthaltend cholesterolester transfer-protein inhibitoren
FR2838349B1 (fr) * 2002-04-15 2004-06-25 Laurence Paris Compositions liquides pour capsules molle a liberation prolongee et leur procede de fabrication
KR100533460B1 (ko) * 2002-07-20 2005-12-08 대화제약 주식회사 난용성 약물의 가용화용 점막흡착성 조성물, 이를 이용한난용성 약물의 가용화용 제형 및 이들의 제조 방법
US20070092559A1 (en) * 2005-10-24 2007-04-26 Jinghua Yuan Liquid dosage forms having enteric properties of delayed and then sustained release
FR3029792B1 (fr) * 2014-12-15 2018-01-26 Societe D'exploitation De Produits Pour Les Industries Chimiques Seppic Liberation maitrisee de substances actives.
KR20170001569U (ko) 2015-10-27 2017-05-10 이제홍 쑥뜸장치

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH05505807A (ja) * 1990-03-30 1993-08-26 アルザ・コーポレーション 細胞毒性物質と透過促進剤を含む混合物
GB9113872D0 (en) * 1991-06-27 1991-08-14 Sandoz Ag Improvements in or relating to organic compounds
HU215966B (hu) * 1994-11-21 1999-07-28 BIOGAL Gyógyszergyár Rt. Orálisan alkalmazható, ciklosporint tartalmazó, összetett emulzió-előkoncentrátum
KR0167613B1 (ko) * 1994-12-28 1999-01-15 한스 루돌프 하우스, 니콜 케르커 사이클로스포린-함유 연질캅셀제 조성물
NZ280689A (en) * 1995-12-15 1997-08-22 Bernard Charles Sherma Sherman Pharmaceutical composition comprising a cyclosporipharmaceutical composition comprising a cyclosporin; a tocol, tocopherol or tocotrienol; and propylen; a tocol, tocopherol or tocotrienol; and propylene carbonate or polyethylene glycol ne carbonate or polyethylene glycol
CZ291641B6 (cs) * 1996-06-19 2003-04-16 Novartis Ag Přípravek obsahující cyklosporin

Also Published As

Publication number Publication date
CZ292378B6 (cs) 2003-09-17
IL147369A (en) 2002-12-01
HK1010492A1 (en) 1999-06-25
DE69731072T2 (de) 2005-10-06
PT1413297E (pt) 2008-07-28
IL123676A0 (en) 1998-10-30
ATE392891T1 (de) 2008-05-15
NO981200D0 (no) 1998-03-17
CZ83498A3 (cs) 1998-07-15
JP2000505480A (ja) 2000-05-09
SK283216B6 (sk) 2003-03-04
RU2181055C2 (ru) 2002-04-10
CA2226091A1 (en) 1997-12-24
EP1413297B1 (de) 2008-04-23
ES2227700T3 (es) 2005-04-01
DE69738656T2 (de) 2009-06-04
CN1207044A (zh) 1999-02-03
NO982382L (no) 1998-05-26
CN1494920A (zh) 2004-05-12
AU719251B2 (en) 2000-05-04
ES2305396T3 (es) 2008-11-01
SK283361B6 (sk) 2003-06-03
SI9720010A (sl) 1998-10-31
MX9804414A (es) 1998-09-30
IL123676A (en) 2002-02-10
EP0869810B1 (de) 2004-10-06
JP3519414B2 (ja) 2004-04-12
SG88752A1 (en) 2002-05-21
SI9720011A (sl) 1998-10-31
IL123840A0 (en) 1998-10-30
AU3341197A (en) 1998-01-07
EP1413297A1 (de) 2004-04-28
NZ330062A (en) 2000-01-28
CZ291641B6 (cs) 2003-04-16
PT869810E (pt) 2005-01-31
SK37298A3 (en) 1998-10-07
SI9720010B (sl) 2009-10-31
CA2226091C (en) 1999-02-09
CN1127350C (zh) 2003-11-12
MX9804442A (es) 1998-09-30
NO981200L (no) 1998-03-17
KR20040000379A (ko) 2004-01-03
CZ83598A3 (cs) 1998-07-15
PL325832A1 (en) 1999-01-04
TR199800526T2 (xx) 1999-02-22
MY117765A (en) 2004-08-30
CA2240705A1 (en) 1997-12-24
CY2549B1 (en) 2008-07-02
SK37198A3 (en) 1998-10-07
ATE278412T1 (de) 2004-10-15
CA2240705C (en) 2007-07-31
NO321921B1 (no) 2006-07-24
IL147369A0 (en) 2002-08-14
NO982382D0 (no) 1998-05-26
TR199800525T2 (xx) 1999-02-22
IL123840A (en) 2002-07-25
JP2004043511A (ja) 2004-02-12
EP0869810A1 (de) 1998-10-14
BR9706804A (pt) 1999-11-03
KR20000016761A (ko) 2000-03-25
RU2185187C2 (ru) 2002-07-20
HUP9801109A3 (en) 2000-06-28
PL188500B1 (pl) 2005-02-28
DE69731072D1 (de) 2004-11-11
BR9713811A (pt) 2004-03-02
NO323816B1 (no) 2007-07-09
DK0869810T3 (da) 2005-02-07
WO1997048410A1 (en) 1997-12-24
HUP9801109A2 (hu) 1999-08-30

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8328 Change in the person/name/address of the agent

Representative=s name: KROHER, STROBEL RECHTS- UND PATENTANWAELTE, 80336

8339 Ceased/non-payment of the annual fee