DE69736838D1 - Herpesvirus saimiri als viraler vektor - Google Patents
Herpesvirus saimiri als viraler vektorInfo
- Publication number
- DE69736838D1 DE69736838D1 DE69736838T DE69736838T DE69736838D1 DE 69736838 D1 DE69736838 D1 DE 69736838D1 DE 69736838 T DE69736838 T DE 69736838T DE 69736838 T DE69736838 T DE 69736838T DE 69736838 D1 DE69736838 D1 DE 69736838D1
- Authority
- DE
- Germany
- Prior art keywords
- herpesvirus saimiri
- viral vector
- genes
- essential
- viral
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
- 241000701062 Saimiriine gammaherpesvirus 2 Species 0.000 title abstract 2
- 239000013603 viral vector Substances 0.000 title 1
- 108700039887 Essential Genes Proteins 0.000 abstract 3
- 108700005077 Viral Genes Proteins 0.000 abstract 1
- 230000037431 insertion Effects 0.000 abstract 1
- 238000003780 insertion Methods 0.000 abstract 1
- 230000035772 mutation Effects 0.000 abstract 1
- 108090000623 proteins and genes Proteins 0.000 abstract 1
- 102000004169 proteins and genes Human genes 0.000 abstract 1
- 230000010076 replication Effects 0.000 abstract 1
- 230000005727 virus proliferation Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
- C12N15/86—Viral vectors
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/16011—Herpesviridae
- C12N2710/16411—Rhadinovirus, e.g. human herpesvirus 8
- C12N2710/16422—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/16011—Herpesviridae
- C12N2710/16411—Rhadinovirus, e.g. human herpesvirus 8
- C12N2710/16441—Use of virus, viral particle or viral elements as a vector
- C12N2710/16443—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Genetics & Genomics (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Biomedical Technology (AREA)
- Biophysics (AREA)
- Virology (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- General Health & Medical Sciences (AREA)
- Plant Pathology (AREA)
- Microbiology (AREA)
- Physics & Mathematics (AREA)
- Medicinal Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB9618477 | 1996-09-04 | ||
| GBGB9618477.5A GB9618477D0 (en) | 1996-09-04 | 1996-09-04 | Gene therapy |
| PCT/GB1997/002371 WO1998010083A1 (en) | 1996-09-04 | 1997-09-04 | Herpesvirus saimiri as viral vector |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DE69736838D1 true DE69736838D1 (de) | 2006-11-30 |
| DE69736838T2 DE69736838T2 (de) | 2007-10-31 |
Family
ID=10799414
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE69736838T Expired - Fee Related DE69736838T2 (de) | 1996-09-04 | 1997-09-04 | Herpesvirus saimiri als viraler vektor |
Country Status (18)
| Country | Link |
|---|---|
| US (1) | US6379967B1 (de) |
| EP (1) | EP0939828B1 (de) |
| JP (1) | JP2000517191A (de) |
| KR (1) | KR20000068461A (de) |
| CN (1) | CN1237209A (de) |
| AT (1) | ATE342997T1 (de) |
| AU (1) | AU737197B2 (de) |
| BR (1) | BR9711998A (de) |
| CA (1) | CA2264956A1 (de) |
| CZ (1) | CZ69799A3 (de) |
| DE (1) | DE69736838T2 (de) |
| ES (1) | ES2274541T3 (de) |
| GB (1) | GB9618477D0 (de) |
| HU (1) | HUP9904329A3 (de) |
| IL (1) | IL128635A0 (de) |
| NZ (1) | NZ334323A (de) |
| SG (1) | SG91252A1 (de) |
| WO (1) | WO1998010083A1 (de) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9826069D0 (en) * | 1998-11-28 | 1999-01-20 | Univ Leeds | HIV vaccine |
| GB9903694D0 (en) | 1999-02-19 | 1999-04-14 | Univ Leeds | Latency-associated regulatory region |
| US7198924B2 (en) | 2000-12-11 | 2007-04-03 | Invitrogen Corporation | Methods and compositions for synthesis of nucleic acid molecules using multiple recognition sites |
| US7754208B2 (en) | 2001-01-17 | 2010-07-13 | Trubion Pharmaceuticals, Inc. | Binding domain-immunoglobulin fusion proteins |
| US7829084B2 (en) * | 2001-01-17 | 2010-11-09 | Trubion Pharmaceuticals, Inc. | Binding constructs and methods for use thereof |
| AU2003253992A1 (en) * | 2002-07-18 | 2004-02-09 | Robert P. Bennett | Viral vectors containing recombination sites |
| EP1687323A4 (de) | 2003-08-08 | 2009-08-12 | Life Technologies Corp | Verfahren und zusammensetzungen zum nahtlosen klonieren von nukleinsäuremolekülen |
| EP1697534B1 (de) | 2003-12-01 | 2010-06-02 | Life Technologies Corporation | Rekombinationsstellen enthaltende nukleinsäuremoleküle und verfahren zur verwendung davon |
| ES2460517T3 (es) | 2005-07-25 | 2014-05-13 | Emergent Product Development Seattle, Llc | Reducción de células b mediante el uso de moléculas de unión específica a cd37 y de unión específica a cd20 |
| KR101571027B1 (ko) | 2006-06-12 | 2015-11-23 | 이머전트 프로덕트 디벨롭먼트 시애틀, 엘엘씨 | 효과기 기능을 갖는 단일쇄 다가 결합 단백질 |
| AU2008287195A1 (en) * | 2007-07-06 | 2009-02-19 | Emergent Product Development Seattle, Llc | Binding peptides having a C-terminally disposed specific binding domain |
| CN102099377A (zh) * | 2008-04-11 | 2011-06-15 | 新兴产品开发西雅图有限公司 | Cd37免疫治疗剂及其与双功能化学治疗剂的联合 |
| CA2999138C (en) | 2015-09-21 | 2024-05-21 | Aptevo Research And Development Llc | Cd3 binding polypeptides |
| WO2018048869A1 (en) * | 2016-09-06 | 2018-03-15 | Bioventures, Llc | Compositions and methods for generating reversion free attenuated and/or replication incompetent vaccine vectors |
| CN107653345B (zh) * | 2017-11-08 | 2021-04-27 | 中国人民解放军军事医学科学院野战输血研究所 | 猴b病毒实时荧光定量pcr方法及其通用引物、mgb探针与试剂盒 |
| RU2771081C2 (ru) * | 2020-08-25 | 2022-04-26 | Федеральное государственное бюджетное учреждение науки институт биоорганической химии им. академиков М.М. Шемякина и Ю.А. Овчинникова Российской академии наук (ИБХ РАН) | Рекомбинантный штамм Herpesvirus saimiri для получения популяций иммортализованных аутологичных Т-лимфоцитов, экспрессирующих парные химерные рецепторы против опухолевых антигенов CD44 и CD133 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5672344A (en) * | 1987-12-30 | 1997-09-30 | The Regents Of The University Of Michigan | Viral-mediated gene transfer system |
| EP0437516A4 (en) * | 1988-10-06 | 1991-09-25 | Dana Farber Cancer Institute | H. saimiri-htlv-x region vector |
| DE3834157A1 (de) * | 1988-10-07 | 1990-04-19 | Behringwerke Ag | Selektionierbare vektoren fuer humane t-zellen |
-
1996
- 1996-09-04 GB GBGB9618477.5A patent/GB9618477D0/en active Pending
-
1997
- 1997-09-04 HU HU9904329A patent/HUP9904329A3/hu unknown
- 1997-09-04 SG SG200000410A patent/SG91252A1/en unknown
- 1997-09-04 CN CN97199571A patent/CN1237209A/zh active Pending
- 1997-09-04 BR BR9711998-9A patent/BR9711998A/pt not_active Application Discontinuation
- 1997-09-04 CZ CZ99697A patent/CZ69799A3/cs unknown
- 1997-09-04 KR KR1019997001842A patent/KR20000068461A/ko not_active Application Discontinuation
- 1997-09-04 IL IL12863597A patent/IL128635A0/xx unknown
- 1997-09-04 EP EP97919133A patent/EP0939828B1/de not_active Expired - Lifetime
- 1997-09-04 AU AU43071/97A patent/AU737197B2/en not_active Ceased
- 1997-09-04 ES ES97919133T patent/ES2274541T3/es not_active Expired - Lifetime
- 1997-09-04 NZ NZ334323A patent/NZ334323A/en unknown
- 1997-09-04 JP JP10512354A patent/JP2000517191A/ja active Pending
- 1997-09-04 AT AT97919133T patent/ATE342997T1/de not_active IP Right Cessation
- 1997-09-04 WO PCT/GB1997/002371 patent/WO1998010083A1/en active IP Right Grant
- 1997-09-04 US US09/254,326 patent/US6379967B1/en not_active Expired - Fee Related
- 1997-09-04 CA CA002264956A patent/CA2264956A1/en not_active Abandoned
- 1997-09-04 DE DE69736838T patent/DE69736838T2/de not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| HUP9904329A3 (en) | 2002-01-28 |
| CZ69799A3 (cs) | 1999-08-11 |
| JP2000517191A (ja) | 2000-12-26 |
| BR9711998A (pt) | 2000-01-18 |
| NZ334323A (en) | 2000-06-23 |
| KR20000068461A (ko) | 2000-11-25 |
| CN1237209A (zh) | 1999-12-01 |
| EP0939828A1 (de) | 1999-09-08 |
| DE69736838T2 (de) | 2007-10-31 |
| CA2264956A1 (en) | 1998-03-12 |
| EP0939828B1 (de) | 2006-10-18 |
| SG91252A1 (en) | 2002-09-17 |
| AU4307197A (en) | 1998-03-26 |
| US6379967B1 (en) | 2002-04-30 |
| WO1998010083A1 (en) | 1998-03-12 |
| HUP9904329A2 (hu) | 2000-04-28 |
| ES2274541T3 (es) | 2007-05-16 |
| IL128635A0 (en) | 2000-01-31 |
| GB9618477D0 (en) | 1996-10-16 |
| ATE342997T1 (de) | 2006-11-15 |
| AU737197B2 (en) | 2001-08-09 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 8364 | No opposition during term of opposition | ||
| 8339 | Ceased/non-payment of the annual fee |